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KR910021361A - Anti-ulcer substance - Google Patents

Anti-ulcer substance Download PDF

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Publication number
KR910021361A
KR910021361A KR1019910002916A KR910002916A KR910021361A KR 910021361 A KR910021361 A KR 910021361A KR 1019910002916 A KR1019910002916 A KR 1019910002916A KR 910002916 A KR910002916 A KR 910002916A KR 910021361 A KR910021361 A KR 910021361A
Authority
KR
South Korea
Prior art keywords
trimethyl
cyclohepten
dihydroxy
ulcer
substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
KR1019910002916A
Other languages
Korean (ko)
Other versions
KR0169492B1 (en
Inventor
기요까즈 무라까미
스스무 요꾸라
Original Assignee
노베 고지
도오꾜다나베세이야꾸 가부시끼가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 노베 고지, 도오꾜다나베세이야꾸 가부시끼가이샤 filed Critical 노베 고지
Publication of KR910021361A publication Critical patent/KR910021361A/en
Application granted granted Critical
Publication of KR0169492B1 publication Critical patent/KR0169492B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/32—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by aldehydo- or ketonic radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A61K31/125—Camphor; Nuclear substituted derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/78—Separation; Purification; Stabilisation; Use of additives
    • C07C45/79—Separation; Purification; Stabilisation; Use of additives by solid-liquid treatment; by chemisorption
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/717—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups a keto group being part of a seven- to twelve-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

내용 없음No content

Description

항궤양 물질Anti-ulcer substance

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음Since this is an open matter, no full text was included.

Claims (4)

4, 5-디히드록시-2, 6, 6-트리메틸-2-시클로헵텐-1-온.4, 5-dihydroxy-2, 6, 6-trimethyl-2-cyclohepten-1-one. 사이신을 유기용매로 추출하고, 이추출물을 용리액으로서 적당한 혼합용매를 사용하여 컬럼크로마토그래피하여 추출물을 정재하는 것을 특징을 하는 4. 5-디해드록시-2, 6, 6-트리메틸-2-시클로헵텐-1-온의 제조방법.4. 5-Dihaxoxy-2, 6, 6-trimethyl-2-cyclo Method for preparing hepten-1-one. 2, 6, 6-트리메틸시클로헵타-2, 4-디엔-1-온을 산화시켜 모노에폭사이드를 수득한후고리열림반응을 행하는 것을 특징으로 하는 4, 5-디히드록시-2, 6, 6-트리메틸-2-시클로헵텐-1-온의 제조방법.2, 6, 6-trimethylcyclohepta-2, 4-dien-1-one is oxidized to obtain a monoepoxide, and then the ring-opening reaction is carried out. 4, 5-dihydroxy-2, 6 , 6-trimethyl-2-cyclohepten-1-one. 유효성분으로서 4, 5-디히록시-2, 6, 6-트리메틸-2-시클로헵텐-1-온을 함유하는 방법.A method containing 4, 5-dihydroxy-2, 6, 6-trimethyl-2-cyclohepten-1-one as an active ingredient. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019910002916A 1990-02-22 1991-02-22 Anti-ulcer substance Expired - Fee Related KR0169492B1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP39663/1990 1990-02-22
JP3966390 1990-02-22
JP39663/90 1990-02-22
JP325333/90 1990-11-29
JP2325333A JPH0745426B2 (en) 1990-02-22 1990-11-29 New anti-ulcer substance
JP325333/1990 1990-11-29

Publications (2)

Publication Number Publication Date
KR910021361A true KR910021361A (en) 1991-12-20
KR0169492B1 KR0169492B1 (en) 1999-03-20

Family

ID=26379045

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019910002916A Expired - Fee Related KR0169492B1 (en) 1990-02-22 1991-02-22 Anti-ulcer substance

Country Status (8)

Country Link
EP (1) EP0443848B1 (en)
JP (1) JPH0745426B2 (en)
KR (1) KR0169492B1 (en)
AT (1) ATE111883T1 (en)
AU (1) AU633402B2 (en)
DE (1) DE69104083T2 (en)
DK (1) DK0443848T3 (en)
ES (1) ES2060293T3 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2076362A1 (en) * 1991-08-21 1993-02-22 Susumu Yokura Saishin n derivatives, process for preparing same and untiulcer agents containing same
US5610294A (en) 1991-10-11 1997-03-11 The Du Pont Merck Pharmaceutical Company Substituted cyclic carbonyls and derivatives thereof useful as retroviral protease inhibitors
USRE37781E1 (en) 1991-10-11 2002-07-02 Dupont Pharmaceuticals Company Substituted cyclic carbonyls and derivatives thereof useful as retroviral protease inhibitors
US5616578A (en) * 1993-08-26 1997-04-01 The Dupont Merck Pharmaceutical Company Method of treating human immunodeficiency virus infection using a cyclic protease inhibitor in combination with a reverse transcriptase inhibitor
AU696576B2 (en) * 1995-04-12 1998-09-10 Mitsubishi-Tokyo Pharmaceuticals, Inc. 4-amino-5-oxy-2,6,6-trimethyl-2-cycloheptene compounds
US6313110B1 (en) 1999-06-02 2001-11-06 Dupont Pharmaceuticals Company Substituted 2H-1,3-diazapin-2-one useful as an HIV protease inhibitor
US6737087B2 (en) * 2001-03-13 2004-05-18 Sung-jin Kim Composition containing Asiasari Radix extracts for protecting brain cells and improving memory
KR20030012002A (en) * 2001-07-30 2003-02-12 진양제약주식회사 Soft capsule containing Asiasari Radix extract
KR100462788B1 (en) 2001-11-06 2004-12-20 김성진 Composition containing an extract of pericarpium zanthoxyli for protecting brain cells and improving memory
JP4973210B2 (en) * 2006-11-14 2012-07-11 東亞合成株式会社 New synthesis method
JP6454217B2 (en) * 2014-05-13 2019-01-16 積水化学工業株式会社 Modified dialkylaminobenzoic acid-based compound, modified thioxanthone derivative, photocurable resin composition, liquid crystal display element sealing agent, vertical conduction material, and liquid crystal display element

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4749681A (en) * 1986-05-22 1988-06-07 International Flavors & Fragrances Inc. Polyalkyl-substituted oxocycloheptane derivatives, organoleptic uses thereof and processes for preparing same

Also Published As

Publication number Publication date
ES2060293T3 (en) 1994-11-16
DE69104083D1 (en) 1994-10-27
ATE111883T1 (en) 1994-10-15
KR0169492B1 (en) 1999-03-20
JPH03275640A (en) 1991-12-06
EP0443848B1 (en) 1994-09-21
DK0443848T3 (en) 1994-10-17
DE69104083T2 (en) 1995-06-22
AU7125991A (en) 1991-08-29
JPH0745426B2 (en) 1995-05-17
AU633402B2 (en) 1993-01-28
EP0443848A1 (en) 1991-08-28

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