KR890012621A - 함수성 젤라틴계 인공피부 및 그 제조방법 - Google Patents
함수성 젤라틴계 인공피부 및 그 제조방법 Download PDFInfo
- Publication number
- KR890012621A KR890012621A KR1019880002104A KR880002104A KR890012621A KR 890012621 A KR890012621 A KR 890012621A KR 1019880002104 A KR1019880002104 A KR 1019880002104A KR 880002104 A KR880002104 A KR 880002104A KR 890012621 A KR890012621 A KR 890012621A
- Authority
- KR
- South Korea
- Prior art keywords
- gelatin
- artificial skin
- polyvinyl alcohol
- weight ratio
- water
- Prior art date
Links
- 108010010803 Gelatin Proteins 0.000 title claims 6
- 229920000159 gelatin Polymers 0.000 title claims 6
- 239000008273 gelatin Substances 0.000 title claims 6
- 235000019322 gelatine Nutrition 0.000 title claims 6
- 235000011852 gelatine desserts Nutrition 0.000 title claims 6
- 238000002360 preparation method Methods 0.000 title 1
- 239000004599 antimicrobial Substances 0.000 claims description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 2
- 238000000034 method Methods 0.000 claims 10
- 239000000203 mixture Substances 0.000 claims 5
- 239000004372 Polyvinyl alcohol Substances 0.000 claims 4
- 229920002451 polyvinyl alcohol Polymers 0.000 claims 4
- 239000000178 monomer Substances 0.000 claims 3
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 claims 3
- 229920002554 vinyl polymer Polymers 0.000 claims 3
- 239000003505 polymerization initiator Substances 0.000 claims 2
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims 1
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 claims 1
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 claims 1
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical group C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims 1
- 238000012644 addition polymerization Methods 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 150000002978 peroxides Chemical class 0.000 claims 1
- 238000006116 polymerization reaction Methods 0.000 claims 1
- 229910052700 potassium Inorganic materials 0.000 claims 1
- 239000011591 potassium Substances 0.000 claims 1
- 229960003600 silver sulfadiazine Drugs 0.000 claims 1
- UEJSSZHHYBHCEL-UHFFFAOYSA-N silver(1+) sulfadiazinate Chemical group [Ag+].C1=CC(N)=CC=C1S(=O)(=O)[N-]C1=NC=CC=N1 UEJSSZHHYBHCEL-UHFFFAOYSA-N 0.000 claims 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/60—Materials for use in artificial skin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Dermatology (AREA)
- Medicinal Chemistry (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Materials For Medical Uses (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
내용 없음.
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 수증기 투과장치의 개략도.
제2도는 산소투과장치의 개략도.
제3도는 실험 1에 따른 항균제 방출기동.
Claims (11)
- pH가 1 내지 6인 수용액에 젤라틴과 폴리비닐 알코올을 중량비로 약 1:0.5 내지 1:3의 비율로 혼합하여 균일의 혼합체를 형성하고, 50-70℃의 온도하에 상기 젤라틴 및 폴리비닐알코올과 수용성 비닐 모노머를 중량비로 약 1:0.2 내지 약 1:1로 소량의 중합개시제의 존재하에 부가중합시켜 고함수성 젤라틴계 조성물을 제조하는 방법.
- 제1항에 있어서, 수용성 비닐계 모노머가 N-비닐피롤리돈, 2-히드록시에틸 메타크릴레이트, 아크릴아미드 또는 아크릴산인 것을 특징으로하는 제조방법.
- 제1항에 있어서, pH가 1-3인 것을 특징으로 하는 제조방법.
- 제1항에 있어서, 중합온도가 약 70℃인 것을 특징으로하는 제조방법.
- 제1항에 있어서, 젤라틴대 폴리비닐알코올의 중량비가 1:0.67 내지 1:1인 것을 특징으로하는 제조방법.
- 제1항 또는 제5항에 있어서, 젤라틴 및 폴리비닐알코올 대 수용성비닐계 모노머의 중량비가 1:0.2 내지 1:0.5인 것을 특징으로하는 제조방법.
- 제1항에 있어서, 중합개시제로 약 0.01몰%의 과산화이중황산칼륨이 사용되는 것을 특징으로하는 제조방법.
- 제1항의 방법에 의해 제조된 인공피부용 조성물.
- 제1항의 방법에 의해 제조된 조성물을 100-500㎛로 박막화된 인공피부.
- 제1항의 방법에 의해 제조된 조성물에 1-10중량%의 항균제를 혼합하여 100-500㎛로 박막화된 인공피부.
- 제9항에 있어서, 항균제가 실버설파다이아진인 것을 특징으로하는 인공피부.※ 참고사항:최초출원 내용에 의하여 공개하는 것임.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019880002104A KR900006892B1 (ko) | 1988-02-29 | 1988-02-29 | 함수성 젤라틴계 인공피부 및 그 제조방법 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1019880002104A KR900006892B1 (ko) | 1988-02-29 | 1988-02-29 | 함수성 젤라틴계 인공피부 및 그 제조방법 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR890012621A true KR890012621A (ko) | 1989-09-18 |
| KR900006892B1 KR900006892B1 (ko) | 1990-09-24 |
Family
ID=19272547
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019880002104A KR900006892B1 (ko) | 1988-02-29 | 1988-02-29 | 함수성 젤라틴계 인공피부 및 그 제조방법 |
Country Status (1)
| Country | Link |
|---|---|
| KR (1) | KR900006892B1 (ko) |
-
1988
- 1988-02-29 KR KR1019880002104A patent/KR900006892B1/ko active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| KR900006892B1 (ko) | 1990-09-24 |
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