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KR890001942A - (±)-시스 또는 (±)-트란스-퍼메트르산의 광학 분할법 - Google Patents

(±)-시스 또는 (±)-트란스-퍼메트르산의 광학 분할법 Download PDF

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Publication number
KR890001942A
KR890001942A KR1019880008556A KR880008556A KR890001942A KR 890001942 A KR890001942 A KR 890001942A KR 1019880008556 A KR1019880008556 A KR 1019880008556A KR 880008556 A KR880008556 A KR 880008556A KR 890001942 A KR890001942 A KR 890001942A
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South Korea
Prior art keywords
cis
optically active
trans
acid
permethic
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KR1019880008556A
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English (en)
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KR0147834B1 (ko
Inventor
히로유끼 노히라
신이찌 요시다
Original Assignee
나까무라 히사오
가부시끼가이샤 구라레
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Priority claimed from JP62173563A external-priority patent/JPH0694435B2/ja
Priority claimed from JP62218336A external-priority patent/JPH0720915B2/ja
Application filed by 나까무라 히사오, 가부시끼가이샤 구라레 filed Critical 나까무라 히사오
Publication of KR890001942A publication Critical patent/KR890001942A/ko
Application granted granted Critical
Publication of KR0147834B1 publication Critical patent/KR0147834B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C61/00—Compounds having carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C61/16—Unsaturated compounds
    • C07C61/40—Unsaturated compounds containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00—Separation of optically-active compounds

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)

Abstract

내용없음

Description

(±)-시스 또는 (±)-트란스-퍼메트르산의 광합 분할법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (4)

  1. 분할제로서 광학적 활성의 1-(P-톨릴)에틸아민 또는 광학적 활성의 시스-N-벤질-2-(하이드록시메틸)사이클로헥실아민을 사용하여 (±)-시스-퍼메트르산과 반응시키거나, 분할제로서 광학적 활성의 1-(P-에소프로필페닐)에틸아민, 광학적 활성의 1-에틸벤질아민 또는 광학적 활성의 시스-N-베질-2-(하이드록시메틸)사이클로헥실아민을 사용하여 (±)-트란스-퍼메트르산과 반응시킴을 포함하여, (±)-시스 또는 (±)-트란스-퍼메트르산을 광학 분할하는 방법.
  2. 제 1 항에 있어서, 반응을 용매중에서 수행하는 방법.
  3. 제 2 항에 있어서,상기 용매가 저급 알콜, 저급알킬 메틸 케톤 및 물로 구성된 그룹으로부터 선택되는 방법.
  4. 제 1 항에 있어서, (±)-시스 또는 (±)-트란스-퍼메트르산을 분할제와 반응시키고 ; 생성된 부분입체 이성체염을 반응 혼합물로부터 분리시키고 ; 분리된 부분 이비체 이성체를 먼저 염기로 처리하고 이어서 산으로 처리하여 광학적으로 활성인 시스 또는 트란스-퍼메트르산을 수득하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019880008556A 1987-07-10 1988-07-09 (+-)-시스 또는 (+-)-트란스-퍼메트르산의 광학 분할법 KR0147834B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP62173563A JPH0694435B2 (ja) 1987-07-10 1987-07-10 （±）−シス−ペルメトリン酸の光学分割法
JP62-173563 1987-07-10
JP62-218336 1987-08-31
JP62218336A JPH0720915B2 (ja) 1987-08-31 1987-08-31 （±）−トランス−ペルメトリン酸の光学分割法

Publications (2)

Publication Number Publication Date
KR890001942A true KR890001942A (ko) 1989-04-06
KR0147834B1 KR0147834B1 (ko) 1998-08-17

Family

ID=26495493

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880008556A KR0147834B1 (ko) 1987-07-10 1988-07-09 (+-)-시스 또는 (+-)-트란스-퍼메트르산의 광학 분할법

Country Status (9)

Country Link
US (1) US4845272A (ko)
EP (1) EP0298480B1 (ko)
KR (1) KR0147834B1 (ko)
CN (1) CN1022482C (ko)
AT (1) ATE81497T1 (ko)
CZ (2) CZ277746B6 (ko)
DE (1) DE3875291T2 (ko)
ES (1) ES2052643T3 (ko)
HU (1) HU203518B (ko)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU662299B2 (en) * 1990-09-21 1995-08-31 Smithkline Beecham Corporation Crystallization of optical isomers of leukotriene antagonists
US5214201A (en) * 1991-12-12 1993-05-25 Smithkline Beecham Corporation Crystallization of optical isomers of leukotriene antagonists
DE69213916T2 (de) * 1991-12-29 1997-03-06 Kuraray Co Verfahren zur Herstellung von L-Ambrox
US5280122A (en) * 1992-07-01 1994-01-18 Pfizer Inc. Resolution of 2-benzyl-4-piperidone-succinic acid
JPH06116217A (ja) * 1992-10-02 1994-04-26 Kuraray Co Ltd （±）−シス−４−アミノシクロペント−２−エンカルボン酸誘導体の光学分割法
US5756862A (en) * 1995-08-26 1998-05-26 Nihon Nohyaku Co., Ltd. Production of optically active 2-halo-1-(substituted phenyl)ethanol and substituted styrene oxide
IN183408B (ko) * 1996-11-20 1999-12-25 Kuraray Co
KR19990084855A (ko) * 1998-05-12 1999-12-06 성재갑 시스-퍼메스린산의 광학적 분할방법
AU2001282565A1 (en) * 2000-09-05 2002-03-26 Ajinomoto Co. Inc. Process for preparing optically active carboxylic acid derivative
CN114478230B (zh) * 2020-10-28 2024-04-16 中国科学院大连化学物理研究所 一种3-乙酰基-2,2-二甲基环丙烷羧酸的拆分方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5123497B2 (ko) * 1972-01-07 1976-07-17
US4289711A (en) * 1975-09-05 1981-09-15 Burroughs Wellcome Co. Ester synthesis
DE2800922A1 (de) * 1978-01-10 1979-07-19 Bayer Ag Verfahren zur trennung stereoisomerer vinylcyclopropancarbonsaeuren
EP0010874B1 (en) * 1978-10-27 1983-06-22 Imperial Chemical Industries Plc Process for separating optical isomers of substituted cyclopropane carboxylic acids; amine salts of substituted cyclopropane carboxylic acids; a substituted cyclopropane carboxylic acid
EP0012722B1 (de) * 1978-12-15 1981-12-09 Ciba-Geigy Ag Verfahren zur Herstellung von optisch aktiven, in 3-Stellung substituierten 2-(2',2'-Dihalogenvinyl)-cyclopropan-1-carbonsäuren und deren Derivaten; 4-(2',2',2'-Trihalogenäthyl)-cyclobutan-1-sulfonsäuresalze und deren Herstellung
JPS56108737A (en) * 1980-01-31 1981-08-28 Sumitomo Chem Co Ltd Method for obtaining optically active 2*22dimethyll33 2*22 dichlorovinyl cyclopropanecarboxylic acid
US4542235A (en) * 1982-04-12 1985-09-17 Sumitomo Chemical Company, Limited Method for producing an optically active 2,2-dimethylcyclopropanecarboxylic acid
HU188335B (en) * 1982-11-25 1986-04-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu Process for preparing optically active derivatives of cyclopropane-carboxylic acid
HU188255B (en) * 1983-02-17 1986-03-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu Process for separation of izomers of derivates of cycloprophane carbonic acid

Also Published As

Publication number Publication date
CZ277746B6 (en) 1993-04-14
EP0298480B1 (en) 1992-10-14
DE3875291D1 (de) 1992-11-19
KR0147834B1 (ko) 1998-08-17
HU203518B (en) 1991-08-28
CN1031221A (zh) 1989-02-22
ES2052643T3 (es) 1994-07-16
EP0298480A1 (en) 1989-01-11
CS489888A3 (en) 1992-12-16
DE3875291T2 (de) 1993-05-19
CN1022482C (zh) 1993-10-20
US4845272A (en) 1989-07-04
ATE81497T1 (de) 1992-10-15
HUT47522A (en) 1989-03-28
CZ277908B6 (en) 1993-06-16
CZ173790A3 (en) 1993-02-17

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