KR890000093A - 건선의 치료방법 및 치료용 조성물 - Google Patents
건선의 치료방법 및 치료용 조성물 Download PDFInfo
- Publication number
- KR890000093A KR890000093A KR1019880006883A KR880006883A KR890000093A KR 890000093 A KR890000093 A KR 890000093A KR 1019880006883 A KR1019880006883 A KR 1019880006883A KR 880006883 A KR880006883 A KR 880006883A KR 890000093 A KR890000093 A KR 890000093A
- Authority
- KR
- South Korea
- Prior art keywords
- azidothymidine
- medicament
- topical
- composition
- use according
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract 11
- 201000004681 Psoriasis Diseases 0.000 title claims abstract 5
- 238000000034 method Methods 0.000 title abstract 2
- HBOMLICNUCNMMY-XLPZGREQSA-N zidovudine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](N=[N+]=[N-])C1 HBOMLICNUCNMMY-XLPZGREQSA-N 0.000 claims abstract 13
- 229960002555 zidovudine Drugs 0.000 claims abstract 13
- 239000003795 chemical substances by application Substances 0.000 claims abstract 3
- 239000002674 ointment Substances 0.000 claims abstract 3
- 230000000699 topical effect Effects 0.000 claims abstract 3
- 239000003246 corticosteroid Substances 0.000 claims abstract 2
- 239000006071 cream Substances 0.000 claims abstract 2
- 239000006210 lotion Substances 0.000 claims abstract 2
- 239000003814 drug Substances 0.000 claims 6
- 238000009472 formulation Methods 0.000 claims 4
- 239000012049 topical pharmaceutical composition Substances 0.000 claims 3
- QTWJRLJHJPIABL-UHFFFAOYSA-N 2-methylphenol;3-methylphenol;4-methylphenol Chemical compound CC1=CC=C(O)C=C1.CC1=CC=CC(O)=C1.CC1=CC=CC=C1O QTWJRLJHJPIABL-UHFFFAOYSA-N 0.000 claims 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical class [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 claims 1
- NUZWLKWWNNJHPT-UHFFFAOYSA-N anthralin Chemical compound C1C2=CC=CC(O)=C2C(=O)C2=C1C=CC=C2O NUZWLKWWNNJHPT-UHFFFAOYSA-N 0.000 claims 1
- 229930003836 cresol Natural products 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 238000007911 parenteral administration Methods 0.000 claims 1
- 239000006072 paste Substances 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 150000002989 phenols Chemical class 0.000 claims 1
- 239000011593 sulfur Chemical class 0.000 claims 1
- 229910052717 sulfur Inorganic materials 0.000 claims 1
- 239000003860 topical agent Substances 0.000 claims 1
- 239000006208 topical dosage form Substances 0.000 abstract 2
- 206010061218 Inflammation Diseases 0.000 abstract 1
- 230000002682 anti-psoriatic effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000004054 inflammatory process Effects 0.000 abstract 1
- 230000007794 irritation Effects 0.000 abstract 1
- 239000003410 keratolytic agent Substances 0.000 abstract 1
- 230000003902 lesion Effects 0.000 abstract 1
- 239000006186 oral dosage form Substances 0.000 abstract 1
- 239000006201 parenteral dosage form Substances 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/04—Sulfur, selenium or tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
- A61K35/04—Tars; Bitumens; Mineral oils; Ammonium bituminosulfonate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
Claims (13)
- 건선 치료용 약제 제조에 있어서의 아지도티미딘의 용도.
- 제1항에 있어서, 약제가 경구 토여 제제인 용도.
- 제2항에 있어서, 약제가 약 400 내지 2000mg 아지도티미딘/ 일로 경구토여할 수 있는 양의 아지도티미딘을 함유하는 용도.
- 제1항에 있어서, 약제가 비경구 투여 제제인 용도.
- 제4항에 있어서, 약제가 약 100 내지 2000mg인 아지도티미딘/ 일로 비경구 투여할 수 있는 양의 아지도티미딘을 함유하는 용도.
- 제1항에 있어서, 약제가 국소 투여 제제인 용도.
- 제6항에 있어서, 국소투여 제제가 약 0.25 내지 10%농도의 아지도티미딘을 함유하는 용도.
- 제7항에 있어서, 국소 투여 제제가 약 1내지 5%농도의 아지도티미딘을 함유하는 용도.
- 고약, 크림, 연고, 로숀, 페이스트 또는 겔로부터 선택된, 약학적으로 허용되는 국소투여 제제로 아지도티미딘을 함유하는 약학 조성물.
- 제9항에 있어서, 국소투여제제가 약 0.25 내지 10% 아지도 티미딘을 함유하는 조성물.
- 제10항에 있어서, 국소투여 제제가 1 내지 약 5% 아지도 티미딘을 함유하는 조성물.
- 제9항에 있어서, 유효량의 코르티코스테로이드 또는 피부표면-작용 건선치료제를 또한 함유하는 조성물.
- 제9항에 있어서, 피부표면-작용 건선치료제가 치환된 페놀, 타르, 황, 이크탐몰, 크레졸 또는 안트랄린인 조성물.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/059,907 US4804651A (en) | 1987-06-09 | 1987-06-09 | Methods and compositions for the treatment of psoriasis |
US059,907 | 1987-06-09 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR890000093A true KR890000093A (ko) | 1989-03-11 |
KR950014447B1 KR950014447B1 (ko) | 1995-11-28 |
Family
ID=22026060
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019880006883A KR950014447B1 (ko) | 1987-06-09 | 1988-06-09 | 유효 성분으로 아지도티미딘을 함유하는 건선 치료용 약제 |
Country Status (15)
Country | Link |
---|---|
US (1) | US4804651A (ko) |
EP (1) | EP0301206B1 (ko) |
JP (1) | JP2510675B2 (ko) |
KR (1) | KR950014447B1 (ko) |
AT (1) | ATE71301T1 (ko) |
AU (1) | AU606423B2 (ko) |
DE (1) | DE3867560D1 (ko) |
DK (1) | DK310188A (ko) |
ES (1) | ES2038716T3 (ko) |
GR (1) | GR3003785T3 (ko) |
HU (1) | HU200693B (ko) |
IE (1) | IE61091B1 (ko) |
MY (1) | MY103734A (ko) |
PH (1) | PH26517A (ko) |
ZA (1) | ZA884056B (ko) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5527779A (en) * | 1988-03-23 | 1996-06-18 | Top Gold Pty Limited | Topically applied gold organic complex |
JPH0618777B2 (ja) * | 1988-05-27 | 1994-03-16 | アメリカ合衆国 | 精神神経性欠損症の治療に用いられる組成物 |
US5098899A (en) * | 1989-03-06 | 1992-03-24 | Trustees Of Boston University | Method for therapeutically treating psoriatic arthritis using vitamin D analogues and metabolites |
JP2831030B2 (ja) * | 1989-05-12 | 1998-12-02 | 学校法人城西大学 | 3’‐アジド‐3’デオキシチミジンを有効成分とする経皮投与製剤用組成物 |
US5021422A (en) * | 1989-06-08 | 1991-06-04 | Senetek Plc | Method and composition for treating hyperproliferative skin diseases using 6-aminopurine cytokinins |
US5162361A (en) * | 1990-04-10 | 1992-11-10 | The United States Of America As Represented By The Secretary, Department Of Health And Human Services | Method of treating diseases associated with elevated levels of interleukin 1 |
DK0663831T3 (da) * | 1991-12-13 | 1995-07-26 | Searle & Co | Transdermal azidothymidin |
US5654286A (en) * | 1993-05-12 | 1997-08-05 | Hostetler; Karl Y. | Nucleotides for topical treatment of psoriasis, and methods for using same |
US5973010A (en) * | 1998-05-15 | 1999-10-26 | Crawford; Robert L. | Composition for healing skin wounds |
GR1003491B (el) * | 1999-12-21 | 2000-11-30 | Μεθοδος παρασκευης φαρμακοτεχνικου σκευασματος, αλοιφης η κρεμασκαι χρηση του στην αντιμετωπιση και θεραπεια της ψωριασεως και του εκζεματος | |
AU2007223560A1 (en) * | 2006-03-01 | 2007-09-13 | Tristrata, Inc. | Composition and method for topical treatment of tar-responsive dermatological disorders |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0199451B1 (en) * | 1985-03-16 | 1996-03-06 | The Wellcome Foundation Limited | Therapeutic nucleosides |
EP0287215B1 (en) * | 1987-03-16 | 1992-06-17 | The Wellcome Foundation Limited | Therapeutic nucleosides |
-
1987
- 1987-06-09 US US07/059,907 patent/US4804651A/en not_active Expired - Lifetime
-
1988
- 1988-06-07 EP EP88109039A patent/EP0301206B1/en not_active Expired - Lifetime
- 1988-06-07 ZA ZA884056A patent/ZA884056B/xx unknown
- 1988-06-07 DE DE8888109039T patent/DE3867560D1/de not_active Expired - Lifetime
- 1988-06-07 ES ES88109039T patent/ES2038716T3/es not_active Expired - Lifetime
- 1988-06-07 AT AT88109039T patent/ATE71301T1/de not_active IP Right Cessation
- 1988-06-08 IE IE170888A patent/IE61091B1/en not_active IP Right Cessation
- 1988-06-08 MY MYPI88000622A patent/MY103734A/en unknown
- 1988-06-08 AU AU17510/88A patent/AU606423B2/en not_active Expired
- 1988-06-08 DK DK310188A patent/DK310188A/da not_active Application Discontinuation
- 1988-06-09 JP JP63142729A patent/JP2510675B2/ja not_active Expired - Lifetime
- 1988-06-09 HU HU882990A patent/HU200693B/hu not_active IP Right Cessation
- 1988-06-09 KR KR1019880006883A patent/KR950014447B1/ko active IP Right Grant
- 1988-08-08 PH PH37032A patent/PH26517A/en unknown
-
1992
- 1992-02-11 GR GR920400211T patent/GR3003785T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
PH26517A (en) | 1992-08-07 |
US4804651A (en) | 1989-02-14 |
GR3003785T3 (ko) | 1993-03-16 |
IE881708L (en) | 1988-12-09 |
AU1751088A (en) | 1988-12-15 |
EP0301206B1 (en) | 1992-01-08 |
DE3867560D1 (de) | 1992-02-20 |
DK310188D0 (da) | 1988-06-08 |
ES2038716T3 (es) | 1995-04-01 |
DK310188A (da) | 1988-12-12 |
IE61091B1 (en) | 1994-09-21 |
ATE71301T1 (de) | 1992-01-15 |
EP0301206A2 (en) | 1989-02-01 |
JP2510675B2 (ja) | 1996-06-26 |
KR950014447B1 (ko) | 1995-11-28 |
HUT47853A (en) | 1989-04-28 |
EP0301206A3 (en) | 1989-09-06 |
JPS6470417A (en) | 1989-03-15 |
ZA884056B (en) | 1989-06-28 |
AU606423B2 (en) | 1991-02-07 |
MY103734A (en) | 1993-09-30 |
HU200693B (en) | 1990-08-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19880609 |
|
PG1501 | Laying open of application | ||
A201 | Request for examination | ||
PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 19921023 Comment text: Request for Examination of Application Patent event code: PA02011R01I Patent event date: 19880609 Comment text: Patent Application |
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E902 | Notification of reason for refusal | ||
PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 19950713 Patent event code: PE09021S01D |
|
G160 | Decision to publish patent application | ||
PG1605 | Publication of application before grant of patent |
Comment text: Decision on Publication of Application Patent event code: PG16051S01I Patent event date: 19951106 |
|
E701 | Decision to grant or registration of patent right | ||
PE0701 | Decision of registration |
Patent event code: PE07011S01D Comment text: Decision to Grant Registration Patent event date: 19960222 |
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NORF | Unpaid initial registration fee | ||
PC1904 | Unpaid initial registration fee |