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KR880701552A - Penetration enhancer for transdermal administration of systemic drugs - Google Patents

Penetration enhancer for transdermal administration of systemic drugs

Info

Publication number
KR880701552A
KR880701552A KR1019880700635A KR880700635A KR880701552A KR 880701552 A KR880701552 A KR 880701552A KR 1019880700635 A KR1019880700635 A KR 1019880700635A KR 880700635 A KR880700635 A KR 880700635A KR 880701552 A KR880701552 A KR 880701552A
Authority
KR
South Korea
Prior art keywords
transdermal administration
penetration enhancer
systemic drugs
systemic
drugs
Prior art date
Application number
KR1019880700635A
Other languages
Korean (ko)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of KR880701552A publication Critical patent/KR880701552A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019880700635A 1986-10-07 1988-06-04 Penetration enhancer for transdermal administration of systemic drugs KR880701552A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91640286A 1986-10-07 1986-10-07
PCT/US1987/002582 WO1988002626A1 (en) 1986-10-07 1987-10-07 Penetration enhancers for transdermal delivery of systemic agents

Publications (1)

Publication Number Publication Date
KR880701552A true KR880701552A (en) 1988-11-03

Family

ID=25437215

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019880700635A KR880701552A (en) 1986-10-07 1988-06-04 Penetration enhancer for transdermal administration of systemic drugs

Country Status (7)

Country Link
EP (1) EP0325616B1 (en)
JP (1) JPH0729940B2 (en)
KR (1) KR880701552A (en)
AU (1) AU609429B2 (en)
CA (1) CA1319613C (en)
DE (1) DE3750264T2 (en)
WO (1) WO1988002626A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1223327B (en) * 1987-10-28 1990-09-19 Mediolanum Farmaceutici Srl ALIPHATIC HETEROCYCLIC COMPOUNDS N SUBSTITUTED TO FACILITATE THE PASSAGE OF ACTIVE SUBSTANCES THROUGH PHYSIOLOGICAL BARRIERS
CA1334646C (en) * 1988-04-08 1995-03-07 James Vanolden Peck Transdermal penetration enhancers
US9511016B2 (en) * 2007-06-12 2016-12-06 Epicentrx, Inc. Topical composition for treating pain

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3157641A (en) * 1960-05-06 1964-11-17 Dow Chemical Co Preparation of nu, nu'-ethylidene bis (nu-heterocyclic) compounds
US3306910A (en) * 1964-09-14 1967-02-28 Phillips Petroleum Co Production of thiolactam compounds
US3306911A (en) * 1965-08-30 1967-02-28 Phillips Petroleum Co Method for preparing thiolactams
US3823152A (en) * 1970-07-30 1974-07-09 Fujisawa Pharmaceutical Co 3-substituted-2-piperidinethiones and homologues thereof
CH573404A5 (en) * 1972-07-28 1976-03-15 Inventa Ag
US4562075A (en) * 1982-05-20 1985-12-31 Nelson Research & Development Co. Penetration enhancers for transdermal drug delivery of systemic agents
US3991203A (en) * 1975-06-19 1976-11-09 Nelson Research & Development Company Vehicle composition containing 1-substituted azacyclopentan-2-ones
US3989815A (en) * 1975-06-19 1976-11-02 Nelson Research & Development Company Novel N-bis-azacyclopentan-2-onyl alkanes
US4525199A (en) * 1981-05-04 1985-06-25 Nelson Research & Development Co. Method of improved pest control
US4405616A (en) * 1975-06-19 1983-09-20 Nelson Research & Development Company Penetration enhancers for transdermal drug delivery of systemic agents
US4316893A (en) * 1975-06-19 1982-02-23 Nelson Research & Development Co. Vehicle composition containing 1-substituted azacycloalkan-2-ones
BE843140A (en) * 1975-06-19 1976-10-18 AAZACYCLOALCAN-2-ONES 1-SUBSTITUTES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AS EXCIPIENTS
US3989816A (en) * 1975-06-19 1976-11-02 Nelson Research & Development Company Vehicle composition containing 1-substituted azacycloheptan-2-ones
DE2947649A1 (en) * 1979-11-27 1981-08-06 C.F. Spiess & Sohn GmbH & Co, 6719 Kleinkarlbach INSECTICIDES
US4415563A (en) * 1980-04-04 1983-11-15 Nelson Research & Development Company Vehicle composition containing 1-substituted azacyclononan-2-ones
US4444762A (en) * 1980-04-04 1984-04-24 Nelson Research & Development Company Vehicle composition containing 1-substituted azacyclopentan-2-ones
US4424210A (en) * 1980-04-04 1984-01-03 Nelson Research & Development Company Vehicle composition containing 1-substituted azacycloalkan-2-ones
US4423040A (en) * 1980-04-04 1983-12-27 Nelson Research & Development Company Vehicle composition containing 1-substituted azacyclohexan-2-ones
US4311481A (en) * 1981-01-23 1982-01-19 Nelson Research & Development Company Method for improved dyeing
US4310525A (en) * 1981-01-23 1982-01-12 Nelson Research & Development Company Method of treatment of inflammation
FR2519549A1 (en) * 1982-01-08 1983-07-18 Besins Jean Ointments contg. two per cent nitroglycerin - for percutaneous treatment of coronary and cardiac insufficiency
US4552872A (en) * 1983-06-21 1985-11-12 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing corticosteroids
US4557934A (en) * 1983-06-21 1985-12-10 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one
US4537776A (en) * 1983-06-21 1985-08-27 The Procter & Gamble Company Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone
US4605670A (en) * 1984-02-01 1986-08-12 Nitto Electric Industrial Co., Ltd. Method for percutaneously administering metoclopramide
US4637930A (en) * 1984-02-08 1987-01-20 Yamanouchi Pharmaceutical Co, Ltd. Transdermal formulation of nicardipine hydrochloride
US4626539A (en) * 1984-08-10 1986-12-02 E. I. Dupont De Nemours And Company Trandermal delivery of opioids
US4620949A (en) * 1985-04-05 1986-11-04 Texaco Inc. Process for amidocarbonylation of cyclic amides
DE3779833T2 (en) * 1986-01-31 1993-02-04 Whitby Research Inc COMPOSITIONS CONTAINING 1-SUBSTITUTED AZACYCLOALKANES AND THEIR USE.
US4801586A (en) * 1986-04-23 1989-01-31 Nelson Research & Development Co. Penetration enhancers for transdermal delivery of systemic agents
ATE75620T1 (en) * 1986-11-19 1992-05-15 Whitby Research Inc PENETRATION ENHANCERS FOR TRANSDERMAL DELIVERY OF SYSTEMIC DRUGS.
EP0268219A1 (en) * 1986-11-19 1988-05-25 Whitby Research Incorporated Penetration enhancers for transdermal delivery of systemic agents

Also Published As

Publication number Publication date
EP0325616B1 (en) 1994-07-20
JPH02501303A (en) 1990-05-10
JPH0729940B2 (en) 1995-04-05
DE3750264D1 (en) 1994-08-25
AU8151587A (en) 1988-05-06
WO1988002626A1 (en) 1988-04-21
AU609429B2 (en) 1991-05-02
CA1319613C (en) 1993-06-29
EP0325616A4 (en) 1989-12-12
DE3750264T2 (en) 1994-11-17
EP0325616A1 (en) 1989-08-02

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Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19880604

PG1501 Laying open of application
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PA0201 Request for examination

Patent event code: PA02012R01D

Patent event date: 19920918

Comment text: Request for Examination of Application

Patent event code: PA02011R01I

Patent event date: 19880604

Comment text: Patent Application

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 19950601

Patent event code: PE09021S01D

E601 Decision to refuse application
PE0601 Decision on rejection of patent

Patent event date: 19950818

Comment text: Decision to Refuse Application

Patent event code: PE06012S01D

Patent event date: 19950601

Comment text: Notification of reason for refusal

Patent event code: PE06011S01I