KR880701552A - Penetration enhancer for transdermal administration of systemic drugs - Google Patents
Penetration enhancer for transdermal administration of systemic drugsInfo
- Publication number
- KR880701552A KR880701552A KR1019880700635A KR880700635A KR880701552A KR 880701552 A KR880701552 A KR 880701552A KR 1019880700635 A KR1019880700635 A KR 1019880700635A KR 880700635 A KR880700635 A KR 880700635A KR 880701552 A KR880701552 A KR 880701552A
- Authority
- KR
- South Korea
- Prior art keywords
- transdermal administration
- penetration enhancer
- systemic drugs
- systemic
- drugs
- Prior art date
Links
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 239000003961 penetration enhancing agent Substances 0.000 title 1
- 230000009885 systemic effect Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US91640286A | 1986-10-07 | 1986-10-07 | |
PCT/US1987/002582 WO1988002626A1 (en) | 1986-10-07 | 1987-10-07 | Penetration enhancers for transdermal delivery of systemic agents |
Publications (1)
Publication Number | Publication Date |
---|---|
KR880701552A true KR880701552A (en) | 1988-11-03 |
Family
ID=25437215
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019880700635A KR880701552A (en) | 1986-10-07 | 1988-06-04 | Penetration enhancer for transdermal administration of systemic drugs |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0325616B1 (en) |
JP (1) | JPH0729940B2 (en) |
KR (1) | KR880701552A (en) |
AU (1) | AU609429B2 (en) |
CA (1) | CA1319613C (en) |
DE (1) | DE3750264T2 (en) |
WO (1) | WO1988002626A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1223327B (en) * | 1987-10-28 | 1990-09-19 | Mediolanum Farmaceutici Srl | ALIPHATIC HETEROCYCLIC COMPOUNDS N SUBSTITUTED TO FACILITATE THE PASSAGE OF ACTIVE SUBSTANCES THROUGH PHYSIOLOGICAL BARRIERS |
CA1334646C (en) * | 1988-04-08 | 1995-03-07 | James Vanolden Peck | Transdermal penetration enhancers |
US9511016B2 (en) * | 2007-06-12 | 2016-12-06 | Epicentrx, Inc. | Topical composition for treating pain |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3157641A (en) * | 1960-05-06 | 1964-11-17 | Dow Chemical Co | Preparation of nu, nu'-ethylidene bis (nu-heterocyclic) compounds |
US3306910A (en) * | 1964-09-14 | 1967-02-28 | Phillips Petroleum Co | Production of thiolactam compounds |
US3306911A (en) * | 1965-08-30 | 1967-02-28 | Phillips Petroleum Co | Method for preparing thiolactams |
US3823152A (en) * | 1970-07-30 | 1974-07-09 | Fujisawa Pharmaceutical Co | 3-substituted-2-piperidinethiones and homologues thereof |
CH573404A5 (en) * | 1972-07-28 | 1976-03-15 | Inventa Ag | |
US4562075A (en) * | 1982-05-20 | 1985-12-31 | Nelson Research & Development Co. | Penetration enhancers for transdermal drug delivery of systemic agents |
US3991203A (en) * | 1975-06-19 | 1976-11-09 | Nelson Research & Development Company | Vehicle composition containing 1-substituted azacyclopentan-2-ones |
US3989815A (en) * | 1975-06-19 | 1976-11-02 | Nelson Research & Development Company | Novel N-bis-azacyclopentan-2-onyl alkanes |
US4525199A (en) * | 1981-05-04 | 1985-06-25 | Nelson Research & Development Co. | Method of improved pest control |
US4405616A (en) * | 1975-06-19 | 1983-09-20 | Nelson Research & Development Company | Penetration enhancers for transdermal drug delivery of systemic agents |
US4316893A (en) * | 1975-06-19 | 1982-02-23 | Nelson Research & Development Co. | Vehicle composition containing 1-substituted azacycloalkan-2-ones |
BE843140A (en) * | 1975-06-19 | 1976-10-18 | AAZACYCLOALCAN-2-ONES 1-SUBSTITUTES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS AS EXCIPIENTS | |
US3989816A (en) * | 1975-06-19 | 1976-11-02 | Nelson Research & Development Company | Vehicle composition containing 1-substituted azacycloheptan-2-ones |
DE2947649A1 (en) * | 1979-11-27 | 1981-08-06 | C.F. Spiess & Sohn GmbH & Co, 6719 Kleinkarlbach | INSECTICIDES |
US4415563A (en) * | 1980-04-04 | 1983-11-15 | Nelson Research & Development Company | Vehicle composition containing 1-substituted azacyclononan-2-ones |
US4444762A (en) * | 1980-04-04 | 1984-04-24 | Nelson Research & Development Company | Vehicle composition containing 1-substituted azacyclopentan-2-ones |
US4424210A (en) * | 1980-04-04 | 1984-01-03 | Nelson Research & Development Company | Vehicle composition containing 1-substituted azacycloalkan-2-ones |
US4423040A (en) * | 1980-04-04 | 1983-12-27 | Nelson Research & Development Company | Vehicle composition containing 1-substituted azacyclohexan-2-ones |
US4311481A (en) * | 1981-01-23 | 1982-01-19 | Nelson Research & Development Company | Method for improved dyeing |
US4310525A (en) * | 1981-01-23 | 1982-01-12 | Nelson Research & Development Company | Method of treatment of inflammation |
FR2519549A1 (en) * | 1982-01-08 | 1983-07-18 | Besins Jean | Ointments contg. two per cent nitroglycerin - for percutaneous treatment of coronary and cardiac insufficiency |
US4552872A (en) * | 1983-06-21 | 1985-11-12 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing corticosteroids |
US4557934A (en) * | 1983-06-21 | 1985-12-10 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing 1-dodecyl-azacycloheptan-2-one |
US4537776A (en) * | 1983-06-21 | 1985-08-27 | The Procter & Gamble Company | Penetrating topical pharmaceutical compositions containing N-(2-hydroxyethyl) pyrrolidone |
US4605670A (en) * | 1984-02-01 | 1986-08-12 | Nitto Electric Industrial Co., Ltd. | Method for percutaneously administering metoclopramide |
US4637930A (en) * | 1984-02-08 | 1987-01-20 | Yamanouchi Pharmaceutical Co, Ltd. | Transdermal formulation of nicardipine hydrochloride |
US4626539A (en) * | 1984-08-10 | 1986-12-02 | E. I. Dupont De Nemours And Company | Trandermal delivery of opioids |
US4620949A (en) * | 1985-04-05 | 1986-11-04 | Texaco Inc. | Process for amidocarbonylation of cyclic amides |
DE3779833T2 (en) * | 1986-01-31 | 1993-02-04 | Whitby Research Inc | COMPOSITIONS CONTAINING 1-SUBSTITUTED AZACYCLOALKANES AND THEIR USE. |
US4801586A (en) * | 1986-04-23 | 1989-01-31 | Nelson Research & Development Co. | Penetration enhancers for transdermal delivery of systemic agents |
ATE75620T1 (en) * | 1986-11-19 | 1992-05-15 | Whitby Research Inc | PENETRATION ENHANCERS FOR TRANSDERMAL DELIVERY OF SYSTEMIC DRUGS. |
EP0268219A1 (en) * | 1986-11-19 | 1988-05-25 | Whitby Research Incorporated | Penetration enhancers for transdermal delivery of systemic agents |
-
1987
- 1987-10-02 CA CA000548460A patent/CA1319613C/en not_active Expired - Fee Related
- 1987-10-07 EP EP87907073A patent/EP0325616B1/en not_active Expired - Lifetime
- 1987-10-07 DE DE3750264T patent/DE3750264T2/en not_active Expired - Fee Related
- 1987-10-07 AU AU81515/87A patent/AU609429B2/en not_active Ceased
- 1987-10-07 JP JP62506430A patent/JPH0729940B2/en not_active Expired - Lifetime
- 1987-10-07 WO PCT/US1987/002582 patent/WO1988002626A1/en active IP Right Grant
-
1988
- 1988-06-04 KR KR1019880700635A patent/KR880701552A/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP0325616B1 (en) | 1994-07-20 |
JPH02501303A (en) | 1990-05-10 |
JPH0729940B2 (en) | 1995-04-05 |
DE3750264D1 (en) | 1994-08-25 |
AU8151587A (en) | 1988-05-06 |
WO1988002626A1 (en) | 1988-04-21 |
AU609429B2 (en) | 1991-05-02 |
CA1319613C (en) | 1993-06-29 |
EP0325616A4 (en) | 1989-12-12 |
DE3750264T2 (en) | 1994-11-17 |
EP0325616A1 (en) | 1989-08-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19880604 |
|
PG1501 | Laying open of application | ||
A201 | Request for examination | ||
PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 19920918 Comment text: Request for Examination of Application Patent event code: PA02011R01I Patent event date: 19880604 Comment text: Patent Application |
|
E902 | Notification of reason for refusal | ||
PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 19950601 Patent event code: PE09021S01D |
|
E601 | Decision to refuse application | ||
PE0601 | Decision on rejection of patent |
Patent event date: 19950818 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 19950601 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |