KR870008511A - 지효성 거환(巨丸) 배합물의 제조방법 - Google Patents
지효성 거환(巨丸) 배합물의 제조방법 Download PDFInfo
- Publication number
- KR870008511A KR870008511A KR870002083A KR870002083A KR870008511A KR 870008511 A KR870008511 A KR 870008511A KR 870002083 A KR870002083 A KR 870002083A KR 870002083 A KR870002083 A KR 870002083A KR 870008511 A KR870008511 A KR 870008511A
- Authority
- KR
- South Korea
- Prior art keywords
- mixture
- mold
- preparing
- dry
- antibiotic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 title claims 7
- 150000002678 macrocyclic compounds Chemical class 0.000 title claims 2
- 239000000203 mixture Substances 0.000 claims 8
- 241000238631 Hexapoda Species 0.000 claims 2
- HLFSDGLLUJUHTE-SNVBAGLBSA-N Levamisole Chemical group C1([C@H]2CN3CCSC3=N2)=CC=CC=C1 HLFSDGLLUJUHTE-SNVBAGLBSA-N 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 2
- 230000003115 biocidal effect Effects 0.000 claims 2
- 239000000945 filler Substances 0.000 claims 2
- 239000003630 growth substance Substances 0.000 claims 2
- WJFKNYWRSNBZNX-UHFFFAOYSA-N 10H-phenothiazine Chemical compound C1=CC=C2NC3=CC=CC=C3SC2=C1 WJFKNYWRSNBZNX-UHFFFAOYSA-N 0.000 claims 1
- AZSNMRSAGSSBNP-UHFFFAOYSA-N 22,23-dihydroavermectin B1a Natural products C1CC(C)C(C(C)CC)OC21OC(CC=C(C)C(OC1OC(C)C(OC3OC(C)C(O)C(OC)C3)C(OC)C1)C(C)C=CC=C1C3(C(C(=O)O4)C=C(C)C(O)C3OC1)O)CC4C2 AZSNMRSAGSSBNP-UHFFFAOYSA-N 0.000 claims 1
- SPBDXSGPUHCETR-JFUDTMANSA-N 8883yp2r6d Chemical compound O1[C@@H](C)[C@H](O)[C@@H](OC)C[C@@H]1O[C@@H]1[C@@H](OC)C[C@H](O[C@@H]2C(=C/C[C@@H]3C[C@@H](C[C@@]4(O[C@@H]([C@@H](C)CC4)C(C)C)O3)OC(=O)[C@@H]3C=C(C)[C@@H](O)[C@H]4OC\C([C@@]34O)=C/C=C/[C@@H]2C)/C)O[C@H]1C.C1C[C@H](C)[C@@H]([C@@H](C)CC)O[C@@]21O[C@H](C\C=C(C)\[C@@H](O[C@@H]1O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C1)[C@@H](C)\C=C\C=C/1[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\1)O)C[C@H]4C2 SPBDXSGPUHCETR-JFUDTMANSA-N 0.000 claims 1
- 239000005893 Diflubenzuron Substances 0.000 claims 1
- 239000004606 Fillers/Extenders Substances 0.000 claims 1
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 claims 1
- 239000004721 Polyphenylene oxide Substances 0.000 claims 1
- 239000004098 Tetracycline Substances 0.000 claims 1
- TZCXTZWJZNENPQ-UHFFFAOYSA-L barium sulfate Chemical group [Ba+2].[O-]S([O-])(=O)=O TZCXTZWJZNENPQ-UHFFFAOYSA-L 0.000 claims 1
- 229910052601 baryte Inorganic materials 0.000 claims 1
- 239000010428 baryte Substances 0.000 claims 1
- 238000001816 cooling Methods 0.000 claims 1
- 125000004122 cyclic group Chemical group 0.000 claims 1
- QQQYTWIFVNKMRW-UHFFFAOYSA-N diflubenzuron Chemical group FC1=CC=CC(F)=C1C(=O)NC(=O)NC1=CC=C(Cl)C=C1 QQQYTWIFVNKMRW-UHFFFAOYSA-N 0.000 claims 1
- 229940019503 diflubenzuron Drugs 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 238000001746 injection moulding Methods 0.000 claims 1
- 150000002500 ions Chemical class 0.000 claims 1
- 229960002418 ivermectin Drugs 0.000 claims 1
- 229960001614 levamisole Drugs 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000003204 osmotic effect Effects 0.000 claims 1
- 239000000575 pesticide Substances 0.000 claims 1
- 229950000688 phenothiazine Drugs 0.000 claims 1
- 229920000570 polyether Polymers 0.000 claims 1
- 239000005871 repellent Substances 0.000 claims 1
- 230000002940 repellent Effects 0.000 claims 1
- 229960002135 sulfadimidine Drugs 0.000 claims 1
- ASWVTGNCAZCNNR-UHFFFAOYSA-N sulfamethazine Chemical compound CC1=CC(C)=NC(NS(=O)(=O)C=2C=CC(N)=CC=2)=N1 ASWVTGNCAZCNNR-UHFFFAOYSA-N 0.000 claims 1
- 238000013268 sustained release Methods 0.000 claims 1
- 239000012730 sustained-release form Substances 0.000 claims 1
- 229960002180 tetracycline Drugs 0.000 claims 1
- 229930101283 tetracycline Natural products 0.000 claims 1
- 235000019364 tetracycline Nutrition 0.000 claims 1
- 150000003522 tetracyclines Chemical class 0.000 claims 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 claims 1
- 229960004441 tyrosine Drugs 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0068—Rumen, e.g. rumen bolus
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
- A01N25/34—Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pest Control & Pesticides (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Dentistry (AREA)
- Toxicology (AREA)
- Plant Pathology (AREA)
- Environmental Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measurement Of Radiation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Description
Claims (7)
- (a) 활성 성분 1 내지 20중량% ; 왁스 또는 왁스 혼합물 1.0 내지 40 중량% ; 지방 0 내지 23중량% ; 및 약리학 및 제약학적으로 허용될 수 있는 고밀도의 충전제 20 내지 85중량%로 되어 있는 연화된 건조 혼합물 또는 펠릿화된 건조 혼합물을 주형에 사출시키고, (b) 주형을 냉각해서 거환을 고체화시키고, (c) 성형된 거환을 주형으로부터 제거하는 단계들로 이루어진 지효성 거환 배합물의 제조방법.
- 제 1 항에 있어서, 단계(a)의 사출 성형 공정이, 제 1 항의 건조혼합물 또는 펠릿화된 건조 혼합물을 약 60℃이하의 온도에서 스크루로 공급하고, 혼합물을 혼합물의 연화점 이상의 온도로 점차 가열하고, 연화된 혼합물을 주형에 밀어 넣는 것으로 이루어진 방법.
- 제 2 항에 있어서, 활성 성분이 곤충 성장 조절제, 항생 물질 또는 구충제인 방법.
- 제 3 항에 있어서, 곤충성장 조절제가 디플루벤주론인 방법.
- 제 3 항에 있어서, 항생물질이 아보파르신, 설파메타진, 테트라사이클린, 티로신 또는 폴리에테르 이온 삼투체인 방법.
- 제 3 항에 있어서, 구충제가 레바미솔, 테트라미솔, 이베르멕틴 또는 페노티아진인 방법.
- 제 3,4,5 또는 6항에 있어서, 증량제 또는 충전제가 중정석인 방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83763686A | 1986-03-10 | 1986-03-10 | |
US837636 | 1986-03-10 | ||
US06/837,636 | 1986-03-10 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR870008511A true KR870008511A (ko) | 1987-10-19 |
KR950007203B1 KR950007203B1 (ko) | 1995-07-04 |
Family
ID=25275025
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019870002083A Expired - Fee Related KR950007203B1 (ko) | 1986-03-10 | 1987-03-09 | 지효성 거환(巨丸) 배합물의 제조방법 |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0236901B1 (ko) |
JP (1) | JP2512736B2 (ko) |
KR (1) | KR950007203B1 (ko) |
AT (1) | ATE66600T1 (ko) |
AU (1) | AU596401B2 (ko) |
CA (1) | CA1297019C (ko) |
DD (1) | DD258940A5 (ko) |
DE (1) | DE3772415D1 (ko) |
DK (1) | DK166946B1 (ko) |
ES (1) | ES2024444B3 (ko) |
FI (1) | FI87314C (ko) |
GR (1) | GR3002614T3 (ko) |
HU (1) | HU199284B (ko) |
IE (1) | IE59745B1 (ko) |
IL (1) | IL81750A (ko) |
NO (1) | NO172728C (ko) |
NZ (1) | NZ219493A (ko) |
PT (1) | PT84433B (ko) |
ZA (1) | ZA871694B (ko) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA89135B (en) * | 1988-01-11 | 1989-10-25 | Duphar Int Res | Method of treating hematologic diseases and pharmaceutical composition to be used therefor |
US5322692A (en) * | 1989-02-28 | 1994-06-21 | American Cyanamid Company | Sustained release bolus effective for the prolonged prevention, treatment or control of nematode, acarid and endo- and ectoparasitic infestations of ruminants |
EP0385106B1 (en) * | 1989-02-28 | 1994-03-23 | American Cyanamid Company | Sustained release bolus effective for the prolonged prevention, treatment or control of nematode, acarid and endo- and ectoparasitic infestations of ruminants |
MX9200339A (es) * | 1991-01-28 | 1992-08-01 | Hoechst Ag | Preparado para la liberacion controlada de sustancias activas, que son apropiadas como terapeuticos o para mejorar el crecimiento y el aprovechamiento de los piensos en rumiantes |
GB9306106D0 (en) * | 1993-03-24 | 1993-05-12 | Norbrook Lab Ltd | Sustained release veterinary composition |
WO1995028835A1 (fr) * | 1994-04-21 | 1995-11-02 | Nippon Shinyaku Co., Ltd. | Procede pour produire une matrice de cire contenant un pesticide, et preparation utilisable en agriculture |
SI4037666T1 (sl) | 2020-12-08 | 2024-09-30 | Ruminant Biotech Corp Limited | Izboljšave naprav in postopkov za dostavo snovi živalim |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3535419A (en) * | 1965-12-15 | 1970-10-20 | Syntex Corp | Veterinary compositions and methods |
US4166107A (en) * | 1978-07-25 | 1979-08-28 | The United States Of America As Represented By The Secretary Of Agriculture | Sustained release bolus formulations containing insect growth regulators for control of livestock pests |
EG16027A (en) * | 1982-03-26 | 1986-12-30 | Warner Lambert Co | Hydrophilic polymer composition for injection molding |
EP0201792A3 (en) * | 1985-05-09 | 1988-07-20 | American Cyanamid Company | Larvicidal compositions |
-
1987
- 1987-03-02 ES ES87102920T patent/ES2024444B3/es not_active Expired - Lifetime
- 1987-03-02 DE DE8787102920T patent/DE3772415D1/de not_active Expired - Fee Related
- 1987-03-02 AT AT87102920T patent/ATE66600T1/de not_active IP Right Cessation
- 1987-03-02 EP EP87102920A patent/EP0236901B1/en not_active Expired - Lifetime
- 1987-03-03 IL IL81750A patent/IL81750A/xx not_active IP Right Cessation
- 1987-03-04 NZ NZ219493A patent/NZ219493A/xx unknown
- 1987-03-06 DK DK116587A patent/DK166946B1/da not_active IP Right Cessation
- 1987-03-06 CA CA000531313A patent/CA1297019C/en not_active Expired - Fee Related
- 1987-03-09 ZA ZA871694A patent/ZA871694B/xx unknown
- 1987-03-09 AU AU69819/87A patent/AU596401B2/en not_active Ceased
- 1987-03-09 IE IE59287A patent/IE59745B1/en not_active IP Right Cessation
- 1987-03-09 NO NO870971A patent/NO172728C/no unknown
- 1987-03-09 FI FI871016A patent/FI87314C/fi not_active IP Right Cessation
- 1987-03-09 HU HU87993A patent/HU199284B/hu not_active IP Right Cessation
- 1987-03-09 PT PT84433A patent/PT84433B/pt unknown
- 1987-03-09 KR KR1019870002083A patent/KR950007203B1/ko not_active Expired - Fee Related
- 1987-03-10 JP JP62053187A patent/JP2512736B2/ja not_active Expired - Fee Related
- 1987-03-10 DD DD87300634A patent/DD258940A5/de unknown
-
1991
- 1991-08-29 GR GR91400178T patent/GR3002614T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DK116587A (da) | 1987-09-11 |
ATE66600T1 (de) | 1991-09-15 |
JPS62265217A (ja) | 1987-11-18 |
DK166946B1 (da) | 1993-08-09 |
AU6981987A (en) | 1987-09-17 |
PT84433B (pt) | 1989-10-04 |
NO172728C (no) | 1993-09-01 |
NO172728B (no) | 1993-05-24 |
ES2024444B3 (es) | 1992-03-01 |
DK116587D0 (da) | 1987-03-06 |
CA1297019C (en) | 1992-03-10 |
HUT43949A (en) | 1988-01-28 |
NZ219493A (en) | 1990-09-26 |
DD258940A5 (de) | 1988-08-10 |
EP0236901B1 (en) | 1991-08-28 |
IL81750A (en) | 1990-08-31 |
EP0236901A3 (en) | 1988-01-27 |
IE59745B1 (en) | 1994-03-23 |
EP0236901A2 (en) | 1987-09-16 |
PT84433A (en) | 1987-04-01 |
HU199284B (en) | 1990-02-28 |
NO870971L (no) | 1987-09-11 |
DE3772415D1 (de) | 1991-10-02 |
FI871016L (fi) | 1987-09-11 |
IE870592L (en) | 1987-09-10 |
NO870971D0 (no) | 1987-03-09 |
JP2512736B2 (ja) | 1996-07-03 |
FI871016A0 (fi) | 1987-03-09 |
FI87314B (fi) | 1992-09-15 |
GR3002614T3 (en) | 1993-01-25 |
FI87314C (fi) | 1992-12-28 |
IL81750A0 (en) | 1987-10-20 |
ZA871694B (en) | 1987-08-28 |
AU596401B2 (en) | 1990-05-03 |
KR950007203B1 (ko) | 1995-07-04 |
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Legal Events
Date | Code | Title | Description |
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PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19870309 |
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A201 | Request for examination | ||
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Patent event code: PA02012R01D Patent event date: 19920220 Comment text: Request for Examination of Application Patent event code: PA02011R01I Patent event date: 19870309 Comment text: Patent Application |
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Comment text: Notification of reason for refusal Patent event date: 19950222 Patent event code: PE09021S01D |
|
G160 | Decision to publish patent application | ||
PG1605 | Publication of application before grant of patent |
Comment text: Decision on Publication of Application Patent event code: PG16051S01I Patent event date: 19950609 |
|
E701 | Decision to grant or registration of patent right | ||
PE0701 | Decision of registration |
Patent event code: PE07011S01D Comment text: Decision to Grant Registration Patent event date: 19950928 |
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