KR860008779A - 항체 형성 화합물의 제조방법 - Google Patents
항체 형성 화합물의 제조방법 Download PDFInfo
- Publication number
- KR860008779A KR860008779A KR1019860003420A KR860003420A KR860008779A KR 860008779 A KR860008779 A KR 860008779A KR 1019860003420 A KR1019860003420 A KR 1019860003420A KR 860003420 A KR860003420 A KR 860003420A KR 860008779 A KR860008779 A KR 860008779A
- Authority
- KR
- South Korea
- Prior art keywords
- carrier molecule
- forming compound
- antigenic reagent
- producing antibody
- antibody forming
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title claims 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 claims 7
- 230000000890 antigenic effect Effects 0.000 claims 4
- 239000003153 chemical reaction reagent Substances 0.000 claims 4
- 239000000427 antigen Substances 0.000 claims 2
- 102000036639 antigens Human genes 0.000 claims 2
- 108091007433 antigens Proteins 0.000 claims 2
- 150000004676 glycans Chemical class 0.000 claims 2
- 229920001282 polysaccharide Polymers 0.000 claims 2
- 239000005017 polysaccharide Substances 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 241000894006 Bacteria Species 0.000 claims 1
- 229930186217 Glycolipid Natural products 0.000 claims 1
- 102000003886 Glycoproteins Human genes 0.000 claims 1
- 108090000288 Glycoproteins Proteins 0.000 claims 1
- 241001465754 Metazoa Species 0.000 claims 1
- 102000007562 Serum Albumin Human genes 0.000 claims 1
- 108010071390 Serum Albumin Proteins 0.000 claims 1
- 239000007822 coupling agent Substances 0.000 claims 1
- 239000005556 hormone Substances 0.000 claims 1
- 229940088597 hormone Drugs 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 244000005700 microbiome Species 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6081—Albumin; Keyhole limpet haemocyanin [KLH]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
내용 없음
Description
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 TNP-β-갈락토 시다제 접합물로 피복시킨 플레이트를 사용한 분석결과이다.
제2도는 TNP-오브알부민 접합물로 피복시킨 플레이트를 사용한 분석결과이다.
제3도는 TNP/MSA 접합물로 피복시킨 플레이트를 사용한 분석결과이다.
Claims (7)
- 단독으로 성숙한 대상에 투여할 때 면역 반응을 개시하지 않는 담체 분자에 항원성 시약을 결합시킴을 특징으로 하는, 투여에 의해 항원성 시약에 대한 항체의 형성을 유발시키는 화합물의 제조방법.
- 제1항에 있어서, 담체 분자는 동일한 동물중의 개체, 또는 인체에서 유발시키는 경우 인체로부터 수득하는 방법.
- 제1항에 있어서, 담체 분자가 단백질인 방법.
- 제3항에 있어서, 담체 분자가 혈청 알부민인 방법.
- 제1항에 있어서, 항원성 시약이 펩티드, 다당류, 호르몬 등에서 선택된 합텐인 방법.
- 제1항에 있어서, 항원성 시약이 미생물, 박테리아 또는 마루스 등의 특정 항원이거나, 다당류, 당지질, 당단백질 및 단백질 등의 가용성 항원인 방법.
- 제1항에 있어서, 항원성 시약과 담체 분자의 결합이 커플링제를 통하여 이루어지는 방법.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR06679 | 1985-05-02 | ||
| FR8506679A FR2581313A1 (fr) | 1985-05-02 | 1985-05-02 | Composes suscitant la formation d'anticorps, compositions immunogeniques et compositions immunoprotectrices les contenant et procede d'obtention d'anticorps les mettant en oeuvre |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR860008779A true KR860008779A (ko) | 1986-12-18 |
Family
ID=9318890
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019860003420A KR860008779A (ko) | 1985-05-02 | 1986-05-01 | 항체 형성 화합물의 제조방법 |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0201413A1 (ko) |
| JP (1) | JPS6230727A (ko) |
| KR (1) | KR860008779A (ko) |
| AU (1) | AU5701786A (ko) |
| DK (1) | DK201386A (ko) |
| FR (1) | FR2581313A1 (ko) |
| GR (1) | GR861170B (ko) |
| OA (1) | OA08234A (ko) |
| PT (1) | PT82482B (ko) |
| ZA (1) | ZA863093B (ko) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4004979A (en) * | 1968-03-29 | 1977-01-25 | Agence Nationale De Valorisation De La Recherche (Anvar) | Preparation of active proteins cross-linked to inactive proteins |
| GB1303802A (ko) * | 1969-01-16 | 1973-01-24 | ||
| JPS51101120A (en) * | 1975-02-28 | 1976-09-07 | Dai Ichi Kogyo Seiyaku Co Ltd | Kogen oyobi kotainoseiho |
| CA1075600A (en) * | 1976-07-28 | 1980-04-15 | Gideon Goldstein | Immunoassay for thymopoietin |
| FR2527447A1 (fr) * | 1982-05-27 | 1983-12-02 | Leguern Jacques | Procede d'amelioration metabolique par autohemostimulation potentialisee |
| JPS59186924A (ja) * | 1983-04-08 | 1984-10-23 | Kureha Chem Ind Co Ltd | ヒト免疫グロブリン結合抗腫瘍剤 |
-
1985
- 1985-05-02 FR FR8506679A patent/FR2581313A1/fr not_active Withdrawn
-
1986
- 1986-04-24 ZA ZA863093A patent/ZA863093B/xx unknown
- 1986-04-29 PT PT82482A patent/PT82482B/pt unknown
- 1986-04-29 EP EP86400940A patent/EP0201413A1/fr not_active Withdrawn
- 1986-04-30 OA OA58850A patent/OA08234A/xx unknown
- 1986-04-30 GR GR861170A patent/GR861170B/el unknown
- 1986-05-01 KR KR1019860003420A patent/KR860008779A/ko not_active Application Discontinuation
- 1986-05-01 AU AU57017/86A patent/AU5701786A/en not_active Abandoned
- 1986-05-01 DK DK201386A patent/DK201386A/da unknown
- 1986-05-02 JP JP61102931A patent/JPS6230727A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| GR861170B (en) | 1986-08-14 |
| ZA863093B (en) | 1986-12-30 |
| DK201386D0 (da) | 1986-05-01 |
| PT82482A (fr) | 1986-05-01 |
| DK201386A (da) | 1986-11-03 |
| JPS6230727A (ja) | 1987-02-09 |
| EP0201413A1 (fr) | 1986-12-17 |
| PT82482B (fr) | 1987-09-11 |
| AU5701786A (en) | 1986-11-06 |
| FR2581313A1 (fr) | 1986-11-07 |
| OA08234A (fr) | 1987-10-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19860501 |
|
| PG1501 | Laying open of application | ||
| PC1203 | Withdrawal of no request for examination | ||
| WITN | Application deemed withdrawn, e.g. because no request for examination was filed or no examination fee was paid |