KR860003247A - 티아디아진 화합물 및 그 염의 제조방법 - Google Patents
티아디아진 화합물 및 그 염의 제조방법 Download PDFInfo
- Publication number
- KR860003247A KR860003247A KR1019850008015A KR850008015A KR860003247A KR 860003247 A KR860003247 A KR 860003247A KR 1019850008015 A KR1019850008015 A KR 1019850008015A KR 850008015 A KR850008015 A KR 850008015A KR 860003247 A KR860003247 A KR 860003247A
- Authority
- KR
- South Korea
- Prior art keywords
- compound
- preparing
- formula
- salts
- thiadiazine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Abstract
Description
Claims (1)
- 하기식(II)의 화합물과 하기식(III)의 화합물을 반응시킴을 특징으로 하는 하기식 (I)의 티아디아진 화합물 및 약학적으로 허용 가능한 그 염의 제조방법식중, X는 탄소수 1 내지 3의 알킬기로 임의 치환 가능한 메틸렌이고 ; Y는 활성원자 또는 기이고 ; R은 수소원자 또는 메틸기이고 ; R1은 수소원자 또는 탄소수 1 내지 3의 알킬이고 ; R2는 알킬기, 암모늄이온 또는 알칼리이온이고 ; n은 1 또는 2의 정수이다.※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP227300/84 | 1984-10-29 | ||
JP59227300A JPS61106574A (ja) | 1984-10-29 | 1984-10-29 | オキサ(またはチア)ジアジン誘導体 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR860003247A true KR860003247A (ko) | 1986-05-21 |
KR880002086B1 KR880002086B1 (ko) | 1988-10-15 |
Family
ID=16858652
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1019850008015A KR880002086B1 (ko) | 1984-10-29 | 1985-10-29 | 티아디아진 화합물 및 그 염의 제조방법 |
Country Status (8)
Country | Link |
---|---|
US (1) | US4678785A (ko) |
EP (1) | EP0180158B1 (ko) |
JP (1) | JPS61106574A (ko) |
KR (1) | KR880002086B1 (ko) |
AT (1) | ATE37369T1 (ko) |
CA (1) | CA1246065A (ko) |
DE (1) | DE3565104D1 (ko) |
ES (1) | ES8701174A1 (ko) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1986007059A2 (en) * | 1985-05-25 | 1986-12-04 | Yoshitomi Pharmaceutical Industries, Ltd. | Oxodiazine compounds |
AU614965B2 (en) * | 1987-06-06 | 1991-09-19 | Merck Patent Gesellschaft Mit Beschrankter Haftung | Thiadiazinones |
EP0303418A3 (en) * | 1987-08-11 | 1990-11-07 | Smithkline Beecham Laboratoires Pharmaceutiques | Substituted indolones, useful in the treatment of heart or asthmatic diseases |
GB8816944D0 (en) * | 1988-07-15 | 1988-08-17 | Sobio Lab | Compounds |
GB8901836D0 (en) * | 1989-01-27 | 1989-03-15 | Sobio Lab | Compounds |
JPH02279685A (ja) * | 1989-04-18 | 1990-11-15 | Yoshitomi Pharmaceut Ind Ltd | 新規な結晶構造を有するチアジアジン化合物およびその製造法 |
US5179203A (en) * | 1990-07-31 | 1993-01-12 | Yoshitomi Pharmaceutical Industries Ltd. | Thiadiazine compound with a novel crystalline form |
DE4041074A1 (de) * | 1990-12-21 | 1992-06-25 | Merck Patent Gmbh | Thiadiazinonderivate |
US6703537B1 (en) * | 1997-11-15 | 2004-03-09 | The Procter & Gamble Company | Absorbent article having improved fecal storage structure |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3172252D1 (en) * | 1980-11-14 | 1985-10-17 | Ici Plc | Heterocyclic compounds |
US4495185A (en) * | 1981-11-12 | 1985-01-22 | Imperial Chemical Industries, Plc | 1,2,4-Triazin-3(2H) ones |
CA1199027A (en) * | 1981-11-12 | 1986-01-07 | Stuart D. Mills | Heterocyclic derivatives of pyridazinone, thiadiazinone, oxadiazinone and triazinone |
-
1984
- 1984-10-29 JP JP59227300A patent/JPS61106574A/ja active Granted
-
1985
- 1985-10-22 CA CA000493512A patent/CA1246065A/en not_active Expired
- 1985-10-25 EP EP85113590A patent/EP0180158B1/en not_active Expired
- 1985-10-25 AT AT85113590T patent/ATE37369T1/de not_active IP Right Cessation
- 1985-10-25 DE DE8585113590T patent/DE3565104D1/de not_active Expired
- 1985-10-29 KR KR1019850008015A patent/KR880002086B1/ko not_active IP Right Cessation
- 1985-10-29 US US06/792,402 patent/US4678785A/en not_active Expired - Fee Related
- 1985-10-29 ES ES548330A patent/ES8701174A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ES548330A0 (es) | 1986-11-16 |
ES8701174A1 (es) | 1986-11-16 |
DE3565104D1 (en) | 1988-10-27 |
CA1246065A (en) | 1988-12-06 |
EP0180158A1 (en) | 1986-05-07 |
JPH0129190B2 (ko) | 1989-06-08 |
KR880002086B1 (ko) | 1988-10-15 |
JPS61106574A (ja) | 1986-05-24 |
US4678785A (en) | 1987-07-07 |
ATE37369T1 (de) | 1988-10-15 |
EP0180158B1 (en) | 1988-09-21 |
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Legal Events
Date | Code | Title | Description |
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PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 19851029 |
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A201 | Request for examination | ||
PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 19871028 Comment text: Request for Examination of Application Patent event code: PA02011R01I Patent event date: 19851029 Comment text: Patent Application |
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G160 | Decision to publish patent application | ||
PG1605 | Publication of application before grant of patent |
Comment text: Decision on Publication of Application Patent event code: PG16051S01I Patent event date: 19880914 |
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E701 | Decision to grant or registration of patent right | ||
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Patent event code: PE07011S01D Comment text: Decision to Grant Registration Patent event date: 19890104 |
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Comment text: Registration of Establishment Patent event date: 19890123 Patent event code: PR07011E01D |
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