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KR840003260A - [(3-아미노-3-카르복시)-프로필-1]포스핀산 유도체의 제조법 - Google Patents

[(3-아미노-3-카르복시)-프로필-1]포스핀산 유도체의 제조법 Download PDF

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Publication number
KR840003260A
KR840003260A KR1019830000039A KR830000039A KR840003260A KR 840003260 A KR840003260 A KR 840003260A KR 1019830000039 A KR1019830000039 A KR 1019830000039A KR 830000039 A KR830000039 A KR 830000039A KR 840003260 A KR840003260 A KR 840003260A
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atom
compound
formula
aryl
aralkyl group
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KR1019830000039A
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KR890001825B1 (ko
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노부토 미노와 (외 3)
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나카가와타케시
메이지제과 주식회사
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/44—Amides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/32—Esters thereof
    • C07F9/3205—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/3217—Esters of acyclic unsaturated acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
    • C07F9/32—Esters thereof
    • C07F9/3205—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/3211—Esters of acyclic saturated acids which can have further substituents on alkyl

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

내용 없음

Description

[(3-아미노-3-카르복시)-프로필-1]포스핀산 유도체의 제조법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (3)

  1. 다음식(Ⅰ) 화합물과 다음식(Ⅱ) 화합물을 반응하여 다음식(Ⅲ) 화합물을 생성하여 식(Ⅲ) 화합물과 다음식(Ⅳ) 화합물을 알칼리 존재하에서 반응시켜 생성된 화합물을 가수분해함을 특징으로 하는 다음식(Ⅴ)으로 나타낸[(3-아미노-3-카르복시)-프로필-1]포스핀산 유도체의 제조법
    위 식에서, R1및 R2는 동일하거나 다르며 각각 탄소수 1-5의 직쇄상 또는 분기상의 알킬기, 아릴기 또는 아랄킬기이며 R3및 R4는 동일하거나 다르며 R3,R4및 R5는 각각 수소원자, 탄소수 1-5의 직쇄상 또는 분기상의 알킬기, 아릴기 또는 아랄킬기이며 다만 R3및 R4가 같이 수소원자인 경우에는 제외한다. R6는 수소원자, 탄소수, 1-5의 직쇄상 또는 분기상의 알킬기, 아릴기, 또는 아랄킬기이다. X는 클로린 (Cl)원자 또는 브롬원자(Br)이며, X'는염소(Cl)원자 또는 브롬원자(Br)를 나타낸다.
  2. 다음식(Ⅲ) 화합물과 다음식 화합물(Ⅳ)을 알칼리 존재하에서 반응시켜 생성한 화합물을 가수분해시킴을 특징으로 하는 다음식(Ⅴ)으로 나타낸[(3-아미노-3-카르복시)-프로필-1]포스핀산 유도체의 제조법
    위 식에서, R1및 R2는 같거나 다르며 각각 탄소수 1-5의 직쇄상 또는 분기상의 알킬기, 아릴기 또는 아랄킬기이고 R3및 R4는 같거나 다르며 R3, R4및 R5는 각각 수소원자 , 탄소수 1-5의 직쇄상 또는 분기상의 알킬기, 아릴기 또는 아랄킬기이며, R3및 R4같이 수소원자인 경우는 제외한다. R6는 수소원자, 탄소수 1-5의 직쇄상 또는 분기상의 알킬기, 아릴기 또는 아랄킬기이다.
  3. 다음식(Ⅰ) 화합물과 다음식(Ⅱ) 화합물을 반응시킴을 특징으로 하는 다음식(Ⅲ)으로 나타나는 비닐포스핀 유도체의 제조법
    위 식에서, R1및 R2는 같거나 다르며 각각 탄소수 1-5의 직쇄상 또는 분기상의 알킬기, 아릴기 또는 아랄킬기이며, X는 염소(Cl)원자 또는 브롬(Br)원자이고, X'는 염소(Cl)원자 또는 브롬(Br)원자를 나타낸다.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019830000039A 1982-01-29 1983-01-07 [(3-아미노-3-카르복시)-프로필-1]포스핀산 유도체의 제조법 KR890001825B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP13985 1982-01-29
JP57-13985 1982-01-29
JP57013985A JPS58131993A (ja) 1982-01-29 1982-01-29 ビニルホスフィン酸誘導体の製造法

Publications (2)

Publication Number Publication Date
KR840003260A true KR840003260A (ko) 1984-08-20
KR890001825B1 KR890001825B1 (ko) 1989-05-25

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KR1019830000039A KR890001825B1 (ko) 1982-01-29 1983-01-07 [(3-아미노-3-카르복시)-프로필-1]포스핀산 유도체의 제조법

Country Status (8)

Country Link
US (1) US4510102A (ko)
EP (1) EP0085391B1 (ko)
JP (1) JPS58131993A (ko)
KR (1) KR890001825B1 (ko)
CA (1) CA1212120A (ko)
DE (1) DE3361808D1 (ko)
DK (1) DK166087C (ko)
PL (1) PL137684B1 (ko)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58131993A (ja) * 1982-01-29 1983-08-06 Meiji Seika Kaisha Ltd ビニルホスフィン酸誘導体の製造法
JPS59219297A (ja) * 1983-05-27 1984-12-10 Meiji Seika Kaisha Ltd 光学活性な〔（３−アミノ−３−カルボキシ）プロピル−１〕−ホスフイン酸誘導体の製造法
DE3508573A1 (de) * 1985-03-11 1986-09-11 Hoechst Ag, 6230 Frankfurt Phosphorhaltige (alpha)-aminonitrile und verfahren zu ihrer herstellung
DE3544376A1 (de) * 1985-12-14 1987-06-19 Hoechst Ag Dipeptide mit c-terminalem phosphinothricin, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung unerwuenschten pflanzenwuchses
DE3777325D1 (de) * 1986-10-24 1992-04-16 Monsanto Co 2-amino-4-phosphonyl-buttersaeurederivate und herstellung von 2-amino-4-phosphinyl-butter-saeuren.
US4715994A (en) * 1986-11-05 1987-12-29 Merck & Co., Inc. Novel antibacterial agents and potentiators of carbapenem antibiotics
JP2615777B2 (ja) * 1987-05-26 1997-06-04 日産化学工業株式会社 ホスフィニルアミノ酸誘導体の製造方法
US5300679A (en) * 1987-12-04 1994-04-05 Ciba-Geigy Corporation Substituted propane-phosphinic acid compounds
JP3777397B2 (ja) * 2001-03-08 2006-05-24 独立行政法人科学技術振興機構 光学活性アルケニルホスフィン酸エステル類及びその製造方法
US20090170813A1 (en) * 2005-10-18 2009-07-02 Francine Acher Hypophosphorous Acid Derivatives and their Therapeutical Applications
JP5084014B2 (ja) * 2007-03-19 2012-11-28 Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 リン含有スルホン、スルホキシド誘導体およびそれを中間体としたリン含有α−ケト酸の製造法
DE102008056235A1 (de) * 2008-11-06 2010-05-12 Clariant International Limited Verfahren zur Herstellung von monovinylfunktionalisierten Dialkylphosphinsäuren, deren Salze und Ester und ihre Verwendung
JP2012116776A (ja) * 2010-11-30 2012-06-21 Kyoto Univ ホスホン酸ジエステル誘導体の製造法
CN104262392A (zh) * 2014-10-08 2015-01-07 云南大学 一种乙烯基甲基膦酸酯的合成方法
CN105131032A (zh) * 2015-07-28 2015-12-09 西安近代化学研究所 一种合成l-草铵膦的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5484529A (en) * 1977-12-19 1979-07-05 Meiji Seika Kaisha Ltd Production of d,l-2-amino-4-methylphosphinobutyric acid
DE2963836D1 (en) * 1978-05-25 1982-11-18 Meiji Seika Kaisha Process for producing alkyl 4-(alkoxy methyl phosphinoyl)butyrates and alkyl-(2-amino-4-(alkoxy methyl phosphinoyl)) butyrates
JPS58131993A (ja) * 1982-01-29 1983-08-06 Meiji Seika Kaisha Ltd ビニルホスフィン酸誘導体の製造法

Also Published As

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DK166087C (da) 1993-08-23
DK166087B (da) 1993-03-08
PL240317A1 (en) 1984-05-21
EP0085391A1 (en) 1983-08-10
PL137684B1 (en) 1986-07-31
CA1212120A (en) 1986-09-30
EP0085391B1 (en) 1986-01-15
DK32383A (da) 1983-07-30
JPS6261595B2 (ko) 1987-12-22
DK32383D0 (da) 1983-01-27
JPS58131993A (ja) 1983-08-06
DE3361808D1 (en) 1986-02-27
US4510102A (en) 1985-04-09
KR890001825B1 (ko) 1989-05-25

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