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KR830007545A - 프로스타글란딘의 제조방법 - Google Patents

프로스타글란딘의 제조방법 Download PDF

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Publication number
KR830007545A
KR830007545A KR1019810003810A KR810003810A KR830007545A KR 830007545 A KR830007545 A KR 830007545A KR 1019810003810 A KR1019810003810 A KR 1019810003810A KR 810003810 A KR810003810 A KR 810003810A KR 830007545 A KR830007545 A KR 830007545A
Authority
KR
South Korea
Prior art keywords
producing prostaglandins
hydrogen
compound
formula
prostaglandins
Prior art date
Application number
KR1019810003810A
Other languages
English (en)
Other versions
KR880000892B1 (ko
Inventor
윌리암 홀란드 죠지
페리로젠
갈로-토레스 휴고
Original Assignee
쿠르트 네셀보쉬, 한스 스튀클린
에프, 호프만-롯슈 앤드 캄파니 아크티엔 게젤샤프트
한스 스튀클린
에프, 호프만-라롯슈 앤드 캄파니 아크티엔 게젤샤프트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 쿠르트 네셀보쉬, 한스 스튀클린, 에프, 호프만-롯슈 앤드 캄파니 아크티엔 게젤샤프트, 한스 스튀클린, 에프, 호프만-라롯슈 앤드 캄파니 아크티엔 게젤샤프트 filed Critical 쿠르트 네셀보쉬, 한스 스튀클린
Publication of KR830007545A publication Critical patent/KR830007545A/ko
Application granted granted Critical
Publication of KR880000892B1 publication Critical patent/KR880000892B1/ko

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

내용 없음

Description

프로스타글란딘의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (3)

  1. 다음, 일반식( II )의 화합물을 아세틸화시약으로 처리하여 다음 일반식( I )의 화합물 및 이들의 약학적으로 무독한 염을 제조하는 방법.
    상기식에서, R은 수소 또는 저급알킬이다.
  2. 제 1 항에 있어서, R이 수소인 방법.
  3. 제 1 항에 있어서, R이 메틸인 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019810003810A 1980-10-09 1981-10-08 프로스타글란딘의 제조방법 KR880000892B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/195,576 US4325970A (en) 1980-10-09 1980-10-09 15-Acetyl-prostaglandins
US195,576 1980-10-09

Publications (2)

Publication Number Publication Date
KR830007545A true KR830007545A (ko) 1983-10-21
KR880000892B1 KR880000892B1 (ko) 1988-05-30

Family

ID=22721938

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019810003810A KR880000892B1 (ko) 1980-10-09 1981-10-08 프로스타글란딘의 제조방법

Country Status (26)

Country Link
US (1) US4325970A (ko)
EP (1) EP0049853B1 (ko)
JP (1) JPS5793956A (ko)
KR (1) KR880000892B1 (ko)
AR (1) AR228758A1 (ko)
AT (1) ATE11772T1 (ko)
AU (1) AU548782B2 (ko)
BR (1) BR8106518A (ko)
CA (1) CA1222512A (ko)
CS (1) CS221993B2 (ko)
CU (1) CU35543A1 (ko)
DE (1) DE3168920D1 (ko)
DK (1) DK442981A (ko)
ES (1) ES506097A0 (ko)
FI (1) FI70884C (ko)
GR (1) GR75074B (ko)
HU (1) HU187376B (ko)
IE (1) IE51638B1 (ko)
IL (1) IL63962A (ko)
MC (1) MC1425A1 (ko)
NO (1) NO813411L (ko)
NZ (1) NZ198521A (ko)
PH (1) PH16418A (ko)
PT (1) PT73793B (ko)
ZA (1) ZA816202B (ko)
ZW (1) ZW21881A1 (ko)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0591532A4 (en) * 1991-04-22 1994-11-09 Taisho Pharmaceutical Co Ltd ANALOG OF PROSTAGLANDIN E 1 ?.
DE60234952D1 (de) * 2001-09-10 2010-02-11 Tibotec Pharm Ltd VERFAHREN ZUR HERSTELLUNG VON HEXAHYDROFUROc2,3-BÜFURAN-3-OL
AR038681A1 (es) * 2002-02-14 2005-01-26 Solvay Pharm Bv Formulacion oral de solucion solida de una sustancia activa pobremente soluble en agua

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4141914A (en) * 1972-07-24 1979-02-27 American Cyanamid Company Novel 11-deoxy-11-substituted prostaglandins of the E and F series
GB1440361A (en) * 1972-07-24 1976-06-23 American Cyanamid Co 11-deoxyprostaglandins of the e and f series and the preparation thereof
US4052446A (en) * 1973-08-06 1977-10-04 Hoffmann-La Roche Inc. 11,16-substituted prostaglandins

Also Published As

Publication number Publication date
DE3168920D1 (en) 1985-03-28
CS221993B2 (en) 1983-04-29
ZA816202B (en) 1982-09-29
KR880000892B1 (ko) 1988-05-30
MC1425A1 (fr) 1982-10-18
EP0049853A1 (de) 1982-04-21
JPH039105B2 (ko) 1991-02-07
NZ198521A (en) 1984-04-27
CU35543A1 (es) 1983-05-05
ES8300321A1 (es) 1982-11-01
HU187376B (en) 1985-12-28
ES506097A0 (es) 1982-11-01
IE51638B1 (en) 1987-01-21
FI70884C (fi) 1986-10-27
PT73793A (en) 1981-11-01
AR228758A1 (es) 1983-04-15
PT73793B (en) 1983-10-31
US4325970A (en) 1982-04-20
DK442981A (da) 1982-04-10
IL63962A (en) 1985-05-31
GR75074B (ko) 1984-07-13
NO813411L (no) 1982-04-13
ATE11772T1 (de) 1985-02-15
BR8106518A (pt) 1982-06-29
JPS5793956A (en) 1982-06-11
IL63962A0 (en) 1981-12-31
AU7602481A (en) 1982-04-22
AU548782B2 (en) 1986-01-02
EP0049853B1 (de) 1985-02-13
IE812355L (en) 1982-04-09
CA1222512A (en) 1987-06-02
FI70884B (fi) 1986-07-18
FI813140L (fi) 1982-04-10
ZW21881A1 (en) 1982-05-05
PH16418A (en) 1983-09-29

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