[go: up one dir, main page]

KR830003410A - Method for preparing aminoaryl-β-sulfato ethyl sulfone - Google Patents

Method for preparing aminoaryl-β-sulfato ethyl sulfone

Info

Publication number
KR830003410A
KR830003410A KR1019800002852A KR800002852A KR830003410A KR 830003410 A KR830003410 A KR 830003410A KR 1019800002852 A KR1019800002852 A KR 1019800002852A KR 800002852 A KR800002852 A KR 800002852A KR 830003410 A KR830003410 A KR 830003410A
Authority
KR
South Korea
Prior art keywords
acid
reaction
sulfuric acid
iii
mixture
Prior art date
Application number
KR1019800002852A
Other languages
Korean (ko)
Other versions
KR840001235B1 (en
Inventor
노부지 니시무라
우다지 사와
다께미 도끼에다
슌이찌 하야가와
야스오 데즈까
Original Assignee
히지가따 다께시
스미또모 가가꾸 고오교 가부시끼 가이샤
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 히지가따 다께시, 스미또모 가가꾸 고오교 가부시끼 가이샤 filed Critical 히지가따 다께시
Priority to KR1019800002852A priority Critical patent/KR840001235B1/en
Publication of KR830003410A publication Critical patent/KR830003410A/en
Priority to KR1019840004289A priority patent/KR840001343B1/en
Application granted granted Critical
Publication of KR840001235B1 publication Critical patent/KR840001235B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C07C315/04—Preparation of sulfones; Preparation of sulfoxides by reactions not involving the formation of sulfone or sulfoxide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C315/00—Preparation of sulfones; Preparation of sulfoxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/28—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/48—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C07C317/50—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

내용 없음No content

Description

아미노아릴-β-술파토 에틸술폰의 제조방법Method for preparing aminoaryl-β-sulfato ethyl sulfone

본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음As this is a public information case, the full text was not included.

Claims (7)

하기 일반식(II) 또는(III)으로 표시되는 화합물과 산과의 혼합물을 반응시킴과 동시에 산으로서 황산 및 (또는) 아미도 술폰산을 사용하여 유기용매와 함께 공비, 증발 또는 기화에 의해 휘발성 물질을 제거(1) 시킬 수 있거나, 또는 산으로서 황산, 아미도 술폰산, 클로로술폰산 또는 황산과 아미도술폰산, 클로로술폰산 또는 3 산화 황과의 혼합물을 사용하여 상기의 혼화물을 혼연(2) 시킬 수 있는 반응 대역내에서 반응계로부터 휘발성 물질을 제거시킴을 특징으로 하기 일반식(I)로 표시되는 황산 반에스테르의 제조방법.By reacting a mixture of the compound represented by the following general formula (II) or (III) with an acid and using sulfuric acid and / or amido sulfonic acid as an acid, a volatile substance is azeotropically, evaporated or vaporized with an organic solvent. The above admixture may be removed (1), or the mixture may be kneaded (2) using sulfuric acid, amido sulfonic acid, chlorosulfonic acid or a mixture of sulfuric acid with amidosulfonic acid, chlorosulfonic acid or sulfur trioxide as an acid. A method for producing a sulfuric acid semiester represented by the following general formula (I), wherein the volatile substance is removed from the reaction system in the reaction zone. NH2-A-(-SO2CH2CH2OSO3H)n(I)NH 2 -A-(-SO 2 CH 2 CH 2 OSO 3 H) n (I) (식중, A는 치환, 비치환 방향족 또는 복소환식기이고 n는 1 또는 2의 정수임)(Wherein A is a substituted, unsubstituted aromatic or heterocyclic group and n is an integer of 1 or 2) B-NH-A-(-SO2CH2CH2OH)n(II)B-NH-A-(-SO 2 CH 2 CH 2 OH) n (II) CO(NH-A-SO2CH2CH2OH)2(III)CO (NH-A-SO 2 CH 2 CH 2 OH) 2 (III) (식중, A와 n는 상기에서 정의한 바와 같고, B는 수소원자 또는 산에 의해 가수분해될 수 있는 기임)Wherein A and n are as defined above and B is a group that can be hydrolyzed by a hydrogen atom or an acid. 반응을 40 내지 250℃에서 수행함을 특징으로 하는 특허청구의 범위 제1항 기재의 방법.Method according to claim 1, characterized in that the reaction is carried out at 40 to 250 ℃. 산의 사용량이 일반식(II) 또는 (III)의 화합물중에 있어서의 β-히드록시에틸술포닐기에 대하여 1 내지 3몰임을 특징으로 하는 특허청구의 범위 제1항 기재의 방법.The method according to claim 1, wherein the amount of acid used is 1 to 3 moles with respect to the β-hydroxyethylsulfonyl group in the compound of the formula (II) or (III). 산이 황산임을 특징으로 하는 특허청구의 범위 제1항 기재의 방법.The method according to claim 1, wherein the acid is sulfuric acid. 반응계에 있어서의 황산의 농도가 20 내지 100중량% 임을 특징으로 하는 특허청구의 범위 제4항 기재의 방법.The method according to claim 4, wherein the concentration of sulfuric acid in the reaction system is 20 to 100% by weight. 반응을 규조토, 활성점토, 활성판, 실리카겔, 갈탄 또는 반응 생성물에 상응하는 아미노아릴-β-술파토에틸술폰의 존재하에 수행함을 특징으로 하는 특허청구의 범위 제1항 기재의 방법.The method according to claim 1, wherein the reaction is carried out in the presence of diatomaceous earth, activated clay, active plate, silica gel, lignite or aminoaryl-β-sulfatoethylsulfone corresponding to the reaction product. 반응을 불활성 가스의 존재하 또는 감압하에 수행함을 특징으로 하는 특허청구의 범위 제1항 기재의 방법.Process according to claim 1, characterized in that the reaction is carried out in the presence of an inert gas or under reduced pressure. ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.※ Note: The disclosure is based on the initial application.
KR1019800002852A 1980-07-18 1980-07-18 Method for preparing aminoaryl-β-sulfato ethyl sulfone KR840001235B1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
KR1019800002852A KR840001235B1 (en) 1980-07-18 1980-07-18 Method for preparing aminoaryl-β-sulfato ethyl sulfone
KR1019840004289A KR840001343B1 (en) 1980-07-18 1984-07-20 Process for the preparation of aminoaryl-sulfatoethylsulfone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019800002852A KR840001235B1 (en) 1980-07-18 1980-07-18 Method for preparing aminoaryl-β-sulfato ethyl sulfone

Related Child Applications (1)

Application Number Title Priority Date Filing Date
KR1019840004289A Division KR840001343B1 (en) 1980-07-18 1984-07-20 Process for the preparation of aminoaryl-sulfatoethylsulfone

Publications (2)

Publication Number Publication Date
KR830003410A true KR830003410A (en) 1983-06-20
KR840001235B1 KR840001235B1 (en) 1984-08-23

Family

ID=19217183

Family Applications (2)

Application Number Title Priority Date Filing Date
KR1019800002852A KR840001235B1 (en) 1980-07-18 1980-07-18 Method for preparing aminoaryl-β-sulfato ethyl sulfone
KR1019840004289A KR840001343B1 (en) 1980-07-18 1984-07-20 Process for the preparation of aminoaryl-sulfatoethylsulfone

Family Applications After (1)

Application Number Title Priority Date Filing Date
KR1019840004289A KR840001343B1 (en) 1980-07-18 1984-07-20 Process for the preparation of aminoaryl-sulfatoethylsulfone

Country Status (1)

Country Link
KR (2) KR840001235B1 (en)

Also Published As

Publication number Publication date
KR840001343B1 (en) 1984-09-19
KR840001235B1 (en) 1984-08-23

Similar Documents

Publication Publication Date Title
KR920701104A (en) Method for preparing α, β-unsaturated ketone
Eberson et al. Studies on monoamine oxidase inhibitors. I. The autoxidation of β-phenylisopropylhydrazine as a model reaction for irreversible monoamine oxidase inhibition
D'Souza et al. Thiol-olefin cooxidation (TOCO) reaction. 8. Solvent effects in the oxidation of some thiols with molecular oxygen
DE69636402D1 (en) Reagent and process for the synthesis of organic oxysulfated and fluorinated derivatives
KR940000409A (en) Alkenic acid derivative manufacturing method
RU95117119A (en) METHOD FOR RESTORING SULFUR AND HYDROGEN FROM HYDROGEN SULPHIDE
KR830003410A (en) Method for preparing aminoaryl-β-sulfato ethyl sulfone
KR830010059A (en) Method for preparing aromatic aminosulfonic acid
KR830005191A (en) Method for producing furan derivative
KR900000334A (en) Method for preparing polyarylene sulfide sulfone
ES483249A1 (en) Process for the preparation of dicyclopentylene [2,2'-bis(4-alkyl-6-t-butylphenols)]
FR2373586A1 (en) PREPARATION OF LIQUID COLORANT AND IMPROVED PROCESS FOR THE PRODUCTION OF THE LATTER
KR830005165A (en) Method for preparing alkyl sulfone
KR940011467A (en) N- (2-selphatoethyl) piperazine sulfate and preparation method thereof
GB1425295A (en) Alpha-aminoylidenephthalides and processes for their preparation
KR860003204A (en) Method for preparing diphenylmethylimine derivative
Matsuyama et al. Mechanism of Transylidation of Stable Sulfonium Ylids with Alkyl Sulfides in the Presence of Catalytic Disulfides
KR880007571A (en) Method of Making Modified Elastomers
KR910021360A (en) Hydroxycarbonyl derivative and preparation method thereof
US4420431A (en) Salts of 3-cyano-3-alkene-sulfinic acids and salts of 3-carbamoyl-3-alkene sulfonic acids and preparations thereof
KR910016673A (en) Method for preparing hydroxyphenyl propionate
KR830007605A (en) Method for preparing 2-substituted-phenyl-1,3-perhydrothiazin-4-one
KR850006428A (en) Method for preparing erythromycin acetate
KR850002457A (en) 6-Demethyl-6-deoxy-6-methylene-5-oxytetracycline and 11a-chloro derivative thereof
SU586167A1 (en) Method of preparing alkylsulphoxides

Legal Events

Date Code Title Description
PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19800718

PG1501 Laying open of application
PE0902 Notice of grounds for rejection

Comment text: Notification of reason for refusal

Patent event date: 19830827

Patent event code: PE09021S01D

PG1605 Publication of application before grant of patent

Comment text: Decision on Publication of Application

Patent event code: PG16051S01I

Patent event date: 19840728

PE0701 Decision of registration

Patent event code: PE07011S01D

Comment text: Decision to Grant Registration

Patent event date: 19841030

PR0701 Registration of establishment

Comment text: Registration of Establishment

Patent event date: 19841226

Patent event code: PR07011E01D

PR1002 Payment of registration fee

Payment date: 19841226

End annual number: 3

Start annual number: 1

PR1001 Payment of annual fee

Payment date: 19870710

Start annual number: 4

End annual number: 4

PR1001 Payment of annual fee

Payment date: 19880705

Start annual number: 5

End annual number: 5

PR1001 Payment of annual fee

Payment date: 19890627

Start annual number: 6

End annual number: 6

PR1001 Payment of annual fee

Payment date: 19900703

Start annual number: 7

End annual number: 7

PR1001 Payment of annual fee

Payment date: 19910706

Start annual number: 8

End annual number: 8

PR1001 Payment of annual fee

Payment date: 19920729

Start annual number: 9

End annual number: 9

PC1903 Unpaid annual fee