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Priority to KR7702973ApriorityCriticalpatent/KR790000068B1/en
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Publication of KR790000068B1publicationCriticalpatent/KR790000068B1/en
Organic Low-Molecular-Weight Compounds And Preparation Thereof
(AREA)
Abstract
Guanidines (I; R, R1 = C1-4 alkyl, Het-(CH2)m-z-(CH2)n-,here, Het is alkyl, hydroxyalkyl, hydroxy, halogen, amino substituted or unsubstituted imidazole, pyridine, thiadiazole, Z = O, S, amino or methylene, m=0,1,2,3 integer, n = 1,2,3 integer), useful antagonist to H2 receptor, were prepd. by treatment of alkylisothiocyanates with metallic cyanamide salts. The resulting carbodiimides were reacted with amine to give I.
KR7702973A1977-12-201977-12-20Process for preparation of guanidine derivatives
ExpiredKR790000068B1
(en)