KR20210120456A - Chronic throat disease preventive or therapeutic compositions and methods of manufacture - Google Patents

Abstract

The present invention relates to an extract of at least one or more of plums, quince, Heotgae tree, jujube, pear, pine needles, radish juice, and apple; and a mixture comprising an extract of at least one of dietary sulfur, magnesium sulfate, vitamin D-mixture, soybean lecithin, L-arginine, vitamin C, ornithine, and D-sorbitol. A composition is provided.

Description

Chronic throat disease prevention or treatment composition and manufacturing method

The present invention relates to a composition for alleviating chronic throat disease or irritation of the throat, particularly a composition for preventing or treating a chronic throat disease, and a method for preparing the same.

The common cold is generally considered the most common human disease, affecting people and social contexts in all countries. The common cold and flu are viral diseases limited to the upper respiratory tract. The cause of infection is usually 40% rhinovirus, 10% coronavirus, and a small proportion of adenovirus, parainfluenza virus, bacterial infection.

Cold symptoms can be associated with symptoms such as nasopharyngeal disease, pharyngeal disease, elevated temperature, ear and throat complications, and respiratory disease. Common symptoms include cough (a few days after onset), sore throat, runny nose and fever. Symptoms disappear after 5-10 days. In some cases, especially in the elderly, high-risk group, residual symptoms may persist for up to 3 weeks. The frequency of common cold symptoms tends to increase in older and at-risk patients, mainly due to deterioration of the immune system. Influenza is particularly dangerous for the elderly due to its frequent severity and debilitating complications that increase the risk of death.

In industrialized countries, especially in congested communities, 30% of the population can be affected by colds each winter. The costs of lost work hours, medications, complications and altered social interactions are substantial. Cold illness is sometimes accompanied by complications from the development of bacterial infections that cause fever and pain. In this case, not only symptomatic treatment, but also antibiotic or bacteriostatic treatment is required. Antibiotics lower the body's defenses, causing frequent relapses, especially in children. Cough and cold medicines in children (under 6 years of age) are generally not recommended as they can cause side effects and complications and may provide unproven benefits. About 30% of elderly patients may develop complications (upper respiratory infection, bronchitis, pneumonia). In high-risk groups (severe-risk conditions, heavy smokers, diabetics, persons with physical disabilities, and patients with previous chronic cardiovascular or pulmonary disease), complications can be severe, resulting in increased social/labor costs and hospital admissions.

These cold diseases can develop into chronic pharyngitis, such as chronic inflammation of the throat mucosa, submucosal layer, and lymphoid tissues, which are part of chronic upper respiratory inflammation. The etiological causes of chronic throat disease may include poor diet factors such as overnutrition, overstimulation, and peripheral infectious agents. Clinically, chronic throat diseases due to diseases of the adjacent throat organs are not uncommon. For example, acute or chronic rhinitis/rhinosinusitis, nasal polyps, nasal septal prolapse, allergic rhinitis, adenoid hypertrophy and acute or chronic tonsillitis can cause chronic throat disease.

However, for chronic throat diseases caused by one of the above factors, the therapeutic effect of existing therapies is not satisfactory. In addition, since current drugs have different toxicities and side effects, the development of appropriate new drugs for the prevention and treatment of chronic throat diseases is urgently required.

The present invention has been devised to solve the above-mentioned problems of the prior art.

Accordingly, the present invention is further improved to solve the problems of the prior art as described above, and in particular, to provide a composition for preventing or treating chronic throat disease and a method for preparing the same.

Various problems to be solved by the present invention are not limited to the above-mentioned problems, and other problems not mentioned will be clearly understood by those skilled in the art from the following description.

An embodiment of the present invention provides a composition for preventing or treating a chronic throat disease, and as an example, at least one of plum, quince, heotgae tree, jujube, pear, pine needles, radish juice, and apple. or more extracts; Olive leaf, propolis, and extracts of at least one or more of Nahanaceae; blackcurrant extract; And a composition for preventing or treating chronic throat disease comprising a mixture comprising an extract of at least one of dietary sulfur, magnesium sulfate, vitamin D-mixture, soybean lecithin, L-arginine, vitamin C, ornithine, and D-sorbitol provides

Another embodiment of the present invention provides a composition for preventing or treating chronic throat disease further comprising at least one of mint flavor and lemon flavor as an additive to the composition.

In another embodiment of the present invention, at least one of erythritol, xylitol, apple juice, and enzyme-treated stevia as a sweetener in the composition, DL-malic acid as an antioxidant, citrus extract as a preservative, propylene glycol as a stabilizer, and at least one of an antifoaming agent And, it provides a chronic throat disease prevention or treatment composition further comprising polysorbate-20 as an emulsifier.

Another embodiment of the present invention contains 4.5 to 9% of extracts of at least one or more of plums, quince, heotgae tree, jujube, pear, pine needles, radish juice, and apples in an equal ratio, olive leaf, propolis and 0.15 to 0.2% of at least one or more extracts of Nahan, and 1 to 2% of blackcurrant extract, dietary sulfur, magnesium sulfate, vitamin D-mixture, soybean lecithin, L- Arginine, vitamin C, ornithine, and 0.5 to 1% of extracts of at least one or more of D-sorbitol in an equal ratio, and 0.05 to 0.1% of at least one of mint flavor and lemon flavor as an additive, As an additive of, 0.1 to 0.2% of at least one of erythritol, xylitol, apple juice, and enzyme-treated stevia as a sweetener, 0.1% of DL-malic acid as an antioxidant, 0.1% of citrus extract as a preservative, propylene glycol and an antifoaming agent as a stabilizer It provides a composition for preventing or treating chronic throat disease, comprising at least one of 0.1 to 0.2%, 2 to 5% of polysorbate-20 as an emulsifier, and 93.4 to 81.1% of purified water.

Another embodiment of the present invention is a method for producing the composition, as a raw material for extracting the extract constituting the composition, comprising the steps of: wearing a raw material that is of good quality and does not deteriorate, and has no foreign matter; adding purified water to the raw material 10 times the raw material, and extracting at 30-100 ° C for 1 to 5 hours; Filtering the extract extracted by the extracting with a filter cloth or a stainless steel mesh; Heating the extract filtered by the filtration step to 90 ~ 100 °C in a tank to sterilize for 30 minutes ~ 1 hour; microfiltration of the extract sterilized by the sterilization step with a 0.2 μm filter pad; arbitrarily collecting a sample of the extract filtered by the microfiltration step and inspecting the quality; mixing the purified water with additives and additional additives in a predetermined ratio to the extract, which has been inspected for quality by the step of testing; And it provides a method for preventing or treating chronic throat disease comprising the step of filling and packaging the composition prepared by the mixing step to a predetermined standard.

In another embodiment of the present invention, the packaging unit of the composition packaged by the step of filling and packaging the composition to a predetermined standard may be 1 g, 5 g, 10 g, 20 g, or 200 g.

The present invention has an effect of alleviating a chronic throat disease or throat irritation, in particular, preventing a chronic throat disease or treating a throat disease.

It will be fully understood that embodiments of the present invention may provide various effects not specifically mentioned.

1 depicts a method for preparing one embodiment of a composition of the present invention.

The etiological causes of chronic throat disease may include poor diet factors such as overnutrition, overstimulation, and peripheral infectious agents. Clinically, chronic throat diseases due to diseases of the adjacent throat organs are not uncommon. For example, acute or chronic rhinitis/rhinosinusitis, nasal polyps, nasal septal prolapse, allergic rhinitis, adenoid hypertrophy and acute or chronic tonsillitis can cause chronic throat disease.

However, for chronic throat diseases caused by one of the above factors, the therapeutic effect of existing therapies is not satisfactory.

The present invention relates to a composition effective for preventing and treating chronic throat diseases in which the therapeutic effect of conventional therapies is not satisfactory, and a method for preparing the same.

The main raw materials used for the composition of the present invention are as follows.

Park Ha-hyang

Peppermint flavor is extracted from mint used as a herbal spice. It is characterized by a refreshing and transparent flavor, and it is derived from the main ingredient, menthol. Peppermint is effective in improving various respiratory diseases, including bronchitis, as it has an excellent antibacterial action to remove harmful inflammation in the bronchial tubes.

lemon flavor

Drinking lemons when you have a fever due to a cold or flu will increase your resistance and lower your fever. Lemon, which is good for the respiratory system, cleans the airways, boosts immunity, and has an antibacterial effect, so a sore throat can be treated using lemon.

plum

Plums reduce heat and eliminate inflammation. It is also good when you have a fever due to a cold.

Quince

The medicinal effect of quince is generally good for colds, bronchial diseases, phlegm, and asthma .

hawthorn tree

The fruit, root, and eggplant leaves contain beneficial ingredients such as glucose, malic acid, calcium, furanguranin, hobenin, hobenecid, and habenic acid, which are beneficial for detoxification of alcohol, recovery from fatigue, hangover, and thirst. It helps.

Jujube

It helps the heart, improves blood circulation, and stabilizes nerves.

ship

Although pears are 80-90% water, they are alkaline foods and are rich in vitamins and fiber. It is famous as a fruit that helps the bronchial tubes, and the luteolin component removes phlegm and relieves cough. It is good for asthma and bronchitis, and it is also good for colds, but it can be consumed as pear juice. In addition, it is good for hangover relief because it contains aspartic acid and is rich in sugar and moisture, as it contains many antioxidants such as polyphenols, which helps to improve anticancer effect and immunity.

pine needles

Pine leaves are also helpful in preventing and treating colds. Consistent intake of pine needles has an excellent effect on excreting harmful toxins, inflammation, and waste products from the body.

radish juice

Radish also has high anticancer properties. Indole and glucosinolate, components of radish roots and leaves, have the effect of eliminating the toxicity of carcinogens that have entered the body. Radish is rich in dietary fiber, carotene, iron, calcium, etc., so its calcium content is about 4 times that of radish (root), and radish is rich in vitamin C.

apologize

Apples strengthen the lungs and reduce asthma. The polyphenols rich in apples have the effect of removing free radicals and reducing cholesterol to rejuvenate blood vessels.

olive leaf

Olive leaves have a strong oxidative action to treat skin wound infections, strengthen the immune system, and show excellent efficacy against respiratory and bronchial diseases such as colds. It also controls cholesterol and blood sugar, and improves overall body energy and health.

propolis

Because propolis is effective in antioxidant and antibacterial action, it is nicknamed natural penicillin, and is effective in relieving inflammation and pain. Therefore, it is effective for rhinitis, stomatitis, and inflammation caused by fine dust.

Nahan and

With its excellent anti-inflammatory effect, it is also effective in suppressing inflammation of the lungs and bronchial tubes. In addition, frequent coughing?

blackcurrant

Blackcurrants are rich in vitamins A, B, C, and zinc, which help prevent the intrusion of viruses from the outside and boost immunity to help prevent colds and flu.

dietary sulfur

Dietary sulfur has anti-inflammatory and sterilizing effects, so it is effective against various cold viruses.

magnesium sulfate

Magnesium sulfate can provide immediate relief by inducing relaxation of asthma, one of the respiratory diseases defined by shortness of breath, coughing, wheezing and chest tightness.

Vitamin D-mixture

Vitamin D-compound helps to boost immunity.

Soy Lecithin

The amount of lecithin in the lungs of a smoker is 1/7 less than that of a non-smoker.

Exercising or working makes you tired easily, but taking lecithin helps relieve fatigue by supplying the smoker with insufficient nutrients.

L-Arginine

L-Arginine has the effect of dilating blood vessels and smoothing blood flow.

vitamin C

Vitamin C helps to boost immunity. As the amount of activity increases, the amount of free radicals in the body also increases.

ornithine

Ornithine removes ammonia harmful to the human body, improves liver function, and prevents cough and sore throat.

D-Sorbitol

D-Sorbitol is an excipient and sweetener to neutralize odors in products.

Embodiments of the present invention are manufactured according to the manufacturing method of FIG.

Example 1

As raw materials of good quality, no deterioration, and no foreign substances, each of plum, quince, sagebrush, jujube, pear, pine needles, radish juice, apple, olive leaf, propolis, Nahangwa, and blackcurrant is added in a predetermined amount to the extractor. put in

Purified water is added to the extractor 10 times the amount of the raw material, and the extract is extracted from the raw material for 1 to 5 hours at 30 to 100 ° C. Then, dietary sulfur, magnesium sulfate, vitamin D-mixture, soybean lecithin, L -Arginine, vitamin C, ornithine, and at least one or more extracts of D-sorbitol are mixed to make a mixture, and the mixture is filtered through a filter cloth or stainless steel mesh.

Then, the filtered mixture is heated to 90-100 ° C in a tank to sterilize for 30 minutes to 1 hour, and the sterilized mixture is micro-filtered with a 0.2 μm filter pad, and then a sample of the micro-filtered mixture is collected. Randomly collected and inspected for quality.

The mixture that has passed the quality inspection is mixed with an additive and additional additives and purified water in a predetermined ratio to produce a composition, and then the composition is filled and packaged according to a predetermined standard to provide the consumer for the prevention or treatment of chronic throat disease. is supplied

Example 2

By further including at least one of mint flavor and lemon flavor as an additive to the composition, the effect of preventing or treating chronic throat disease is enhanced.

Example 3

The composition further contains at least one of mint flavor and lemon flavor as an additive, and as an additional additive, at least one of erythritol, xylitol, apple juice, and enzyme-treated stevia as a sweetener, DL-malic acid as an antioxidant, citrus extract as a preservative, and a stabilizer Propylene glycol also increases the effectiveness of preventing or treating chronic throat disease, and adds flavor and preservation.

Example 4

The composition contains, as a component, 4.5 to 9% of at least one or more extracts of plum, quince, honeysuckle, jujube, pear, pine needle, radish juice, and apple in an equal ratio, olive leaf, propolis, and Contains 0.15~0.2% of extracts of at least one or more of Nahanwagae in an equal ratio, contains 1~2% of blackcurrant extract, dietary sulfur, magnesium sulfate, vitamin D-mixture, soybean lecithin, L-arginine, At least one or more extracts of vitamin C, ornithine, and D-sorbitol are contained in an equal ratio in 0.5 to 1%, and as an additive, at least one of mint flavor and lemon flavor is included in 0.05 to 0.1%, and additional additives As a sweetener, 0.1 to 0.2% of at least one of erythritol, xylitol, apple juice, and enzyme-treated stevia, 0.1% of DL-malic acid as an antioxidant, 0.1% of citrus extract as a preservative, At least one of propylene glycol and an antifoaming agent as a stabilizer One contained 0.1 to 0.2%, and 2 to 5% of polysorbate-20 as an emulsifier, and 93.4 to 81.1% of purified water.

Through the inventor's clinical experiments on the embodiments of the present invention, it was found that the present invention has an effect of alleviating chronic throat disease or throat irritation, in particular, the effect of preventing chronic throat disease or treating throat disease.

The embodiment of the present invention may be modified in various forms, and the same members in each drawing are denoted by the same reference numerals, and detailed descriptions of well-known functions and configurations determined to unnecessarily obscure the gist of the present invention are omitted. It should be noted that

The embodiment of the present invention is only one example, and may be modified in various forms without departing from the spirit of the present invention.

In the above, the present invention has been described in detail with reference to specific examples, but since the examples are only for illustrating the present invention, substituted, added and modified embodiments are also provided below without departing from the technical spirit of the present invention. It should be regarded as belonging to the protection scope of the present invention as determined by the claims attached to the

Claims (5)

extracts of at least one or more of apricots, quince, quince, jujube, pear, pine needles, radish juice, and apple;
Olive leaf, propolis, and extracts of at least one or more of Nahanaceae;
blackcurrant extract; and
Dietary sulfur, magnesium sulfate, vitamin D-mixture, soybean lecithin, L-arginine, vitamin C, ornithine, and a mixture comprising an extract of at least one or more of D-sorbitol
A composition for preventing or treating chronic throat disease. The method of claim 1, wherein the composition further comprises at least one of mint flavor and lemon flavor as an additive.
A composition for preventing or treating chronic throat disease. The composition according to claim 2, wherein the composition comprises at least one of erythritol, xylitol, apple juice, and enzyme-treated stevia as a sweetener, DL-malic acid as an antioxidant, citrus extract as a preservative, propylene glycol as a stabilizer, and at least one of an antifoaming agent, and an emulsifier further comprising rhopolysorbate-20
A composition for preventing or treating chronic throat disease. The method according to claim 3, wherein the composition contains 4.5 to 9% of at least one or more extracts of plums, quince, sagebrush, jujube, pear, pine needles, radish juice, and apples in an equal ratio, olive leaf, propolis and 0.15-0.2% of at least one or more extracts of Nahan, and blackcurrant extract, in an equal ratio, containing 1-2%, dietary sulfur, magnesium sulfate, vitamin D-mixture, soybean lecithin, L- At least one or more extracts of arginine, vitamin C, ornithine, and D-sorbitol are contained in an equal ratio in 0.5 to 1%, and at least one of mint flavor and lemon flavor is added as an additive by 0.05 to 0.1%, and erythritol as a sweetener , at least one of xylitol, apple juice, and enzyme-treated stevia in 0.1 to 0.2%, DL-malic acid as an antioxidant 0.1%, citrus extract 0.1% as a preservative, and at least one of propylene glycol and an antifoaming agent as a stabilizer 0.1 to 0.2 %, vegetable glycerin, or 4~5.5% of antifoaming agent, 2~5% of polysorbate-20 as emulsifier, and 93.4~81.1% of purified water.
A composition for preventing or treating chronic throat disease. A method for preparing the composition of claim 1 or 4, comprising:
a. Putting raw materials of good quality, no deterioration, and no foreign substances into the extractor;
b. adding purified water to the extractor at 10 times the amount of the raw material, and extracting the extract from the raw material at 30 to 100°C for 1 to 5 hours;
c. filtering the extract extracted by the extracting with a filter cloth or a stainless mesh network;
d. Heating the extract filtered by the filtration step to 90 ~ 100 °C in a tank to sterilize for 30 minutes ~ 1 hour;
e. microfiltration of the extract sterilized by the sterilization step with a 0.2 μm filter pad;
f. arbitrarily collecting a sample of the extract filtered by the microfiltration step and inspecting the quality;
g. mixing the purified water with additives and additional additives in a predetermined ratio to the extract, which has been inspected for quality by the step of testing; and
h. Comprising the step of filling and packaging the composition prepared by the mixing step to a predetermined standard
A method for preparing a composition for preventing or treating chronic throat disease.

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