KR20200074569A - Dental functional natural gel composition for companion animal and Dental functional silicone material play equipment - Google Patents
Dental functional natural gel composition for companion animal and Dental functional silicone material play equipment Download PDFInfo
- Publication number
- KR20200074569A KR20200074569A KR1020180163113A KR20180163113A KR20200074569A KR 20200074569 A KR20200074569 A KR 20200074569A KR 1020180163113 A KR1020180163113 A KR 1020180163113A KR 20180163113 A KR20180163113 A KR 20180163113A KR 20200074569 A KR20200074569 A KR 20200074569A
- Authority
- KR
- South Korea
- Prior art keywords
- dental
- silicone material
- dental functional
- plaque
- companion animal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 229920001296 polysiloxane Polymers 0.000 title claims abstract description 14
- 239000000463 material Substances 0.000 title claims description 10
- 241001465754 Metazoa Species 0.000 title abstract description 23
- 239000000203 mixture Substances 0.000 title abstract description 20
- 239000004615 ingredient Substances 0.000 claims description 7
- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims 1
- 229910052710 silicon Inorganic materials 0.000 claims 1
- 239000010703 silicon Substances 0.000 claims 1
- 206010006326 Breath odour Diseases 0.000 abstract description 4
- 208000025157 Oral disease Diseases 0.000 abstract description 4
- 208000002925 dental caries Diseases 0.000 abstract description 4
- 208000030194 mouth disease Diseases 0.000 abstract description 4
- 208000014151 Stomatognathic disease Diseases 0.000 abstract description 3
- 201000010099 disease Diseases 0.000 abstract description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 3
- 208000006558 Dental Calculus Diseases 0.000 abstract description 2
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 description 12
- RADKZDMFGJYCBB-UHFFFAOYSA-N pyridoxal hydrochloride Natural products CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 description 9
- 239000000047 product Substances 0.000 description 8
- 229940034610 toothpaste Drugs 0.000 description 6
- 239000000606 toothpaste Substances 0.000 description 6
- 229940011671 vitamin b6 Drugs 0.000 description 6
- 241000241413 Propolis Species 0.000 description 5
- 229940069949 propolis Drugs 0.000 description 5
- 235000019158 vitamin B6 Nutrition 0.000 description 5
- 239000011726 vitamin B6 Substances 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 4
- TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 description 4
- 150000001413 amino acids Chemical class 0.000 description 4
- 235000013376 functional food Nutrition 0.000 description 4
- HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 description 4
- 208000028169 periodontal disease Diseases 0.000 description 4
- 239000000811 xylitol Substances 0.000 description 4
- 229960002675 xylitol Drugs 0.000 description 4
- 235000010447 xylitol Nutrition 0.000 description 4
- HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 description 4
- 241000282472 Canis lupus familiaris Species 0.000 description 3
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 3
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 3
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 3
- 229930003471 Vitamin B2 Natural products 0.000 description 3
- 230000001055 chewing effect Effects 0.000 description 3
- 239000005417 food ingredient Substances 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 210000000214 mouth Anatomy 0.000 description 3
- 210000002200 mouth mucosa Anatomy 0.000 description 3
- 229960002477 riboflavin Drugs 0.000 description 3
- 235000019164 vitamin B2 Nutrition 0.000 description 3
- 239000011716 vitamin B2 Substances 0.000 description 3
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- SRBFZHDQGSBBOR-IOVATXLUSA-N D-xylopyranose Chemical compound O[C@@H]1COC(O)[C@H](O)[C@H]1O SRBFZHDQGSBBOR-IOVATXLUSA-N 0.000 description 2
- 206010012735 Diarrhoea Diseases 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 description 2
- 125000003277 amino group Chemical group 0.000 description 2
- 239000005515 coenzyme Substances 0.000 description 2
- 239000000306 component Substances 0.000 description 2
- 230000006378 damage Effects 0.000 description 2
- 230000006806 disease prevention Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000000796 flavoring agent Substances 0.000 description 2
- 235000013355 food flavoring agent Nutrition 0.000 description 2
- 239000008103 glucose Substances 0.000 description 2
- 229940094952 green tea extract Drugs 0.000 description 2
- 235000020688 green tea extract Nutrition 0.000 description 2
- 238000001727 in vivo Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 230000005012 migration Effects 0.000 description 2
- 238000013508 migration Methods 0.000 description 2
- 229960003512 nicotinic acid Drugs 0.000 description 2
- 235000001968 nicotinic acid Nutrition 0.000 description 2
- 239000011664 nicotinic acid Substances 0.000 description 2
- 239000003755 preservative agent Substances 0.000 description 2
- 230000002335 preservative effect Effects 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 229960003581 pyridoxal Drugs 0.000 description 2
- 235000008164 pyridoxal Nutrition 0.000 description 2
- 239000011674 pyridoxal Substances 0.000 description 2
- NGVDGCNFYWLIFO-UHFFFAOYSA-N pyridoxal 5'-phosphate Chemical compound CC1=NC=C(COP(O)(O)=O)C(C=O)=C1O NGVDGCNFYWLIFO-UHFFFAOYSA-N 0.000 description 2
- NHZMQXZHNVQTQA-UHFFFAOYSA-N pyridoxamine Chemical compound CC1=NC=C(CO)C(CN)=C1O NHZMQXZHNVQTQA-UHFFFAOYSA-N 0.000 description 2
- MGSRCZKZVOBKFT-UHFFFAOYSA-N thymol Chemical compound CC(C)C1=CC=C(C)C=C1O MGSRCZKZVOBKFT-UHFFFAOYSA-N 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 239000000080 wetting agent Substances 0.000 description 2
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-catechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 description 1
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 description 1
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 description 1
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 description 1
- CWVRJTMFETXNAD-FWCWNIRPSA-N 3-O-Caffeoylquinic acid Natural products O[C@H]1[C@@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-FWCWNIRPSA-N 0.000 description 1
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 description 1
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 description 1
- 208000019901 Anxiety disease Diseases 0.000 description 1
- PZIRUHCJZBGLDY-UHFFFAOYSA-N Caffeoylquinic acid Natural products CC(CCC(=O)C(C)C1C(=O)CC2C3CC(O)C4CC(O)CCC4(C)C3CCC12C)C(=O)O PZIRUHCJZBGLDY-UHFFFAOYSA-N 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- 229920001661 Chitosan Polymers 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
- 208000018035 Dental disease Diseases 0.000 description 1
- 229920001875 Ebonite Polymers 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 241000282326 Felis catus Species 0.000 description 1
- 244000043261 Hevea brasiliensis Species 0.000 description 1
- 239000004354 Hydroxyethyl cellulose Substances 0.000 description 1
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 208000000913 Kidney Calculi Diseases 0.000 description 1
- 208000007101 Muscle Cramp Diseases 0.000 description 1
- CWVRJTMFETXNAD-KLZCAUPSSA-N Neochlorogenin-saeure Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O CWVRJTMFETXNAD-KLZCAUPSSA-N 0.000 description 1
- 206010029148 Nephrolithiasis Diseases 0.000 description 1
- 239000005642 Oleic acid Substances 0.000 description 1
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 description 1
- 241001135221 Prevotella intermedia Species 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 239000005844 Thymol Substances 0.000 description 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 229960000458 allantoin Drugs 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 229940024606 amino acid Drugs 0.000 description 1
- -1 and additionally Substances 0.000 description 1
- 208000007502 anemia Diseases 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000001093 anti-cancer Effects 0.000 description 1
- 230000000845 anti-microbial effect Effects 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 230000036506 anxiety Effects 0.000 description 1
- PYMYPHUHKUWMLA-UHFFFAOYSA-N arabinose Natural products OCC(O)C(O)C(O)C=O PYMYPHUHKUWMLA-UHFFFAOYSA-N 0.000 description 1
- SRBFZHDQGSBBOR-UHFFFAOYSA-N beta-D-Pyranose-Lyxose Natural products OC1COC(O)C(O)C1O SRBFZHDQGSBBOR-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 239000004227 calcium gluconate Substances 0.000 description 1
- 229960004494 calcium gluconate Drugs 0.000 description 1
- 235000013927 calcium gluconate Nutrition 0.000 description 1
- NEEHYRZPVYRGPP-UHFFFAOYSA-L calcium;2,3,4,5,6-pentahydroxyhexanoate Chemical compound [Ca+2].OCC(O)C(O)C(O)C(O)C([O-])=O.OCC(O)C(O)C(O)C(O)C([O-])=O NEEHYRZPVYRGPP-UHFFFAOYSA-L 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- ADRVNXBAWSRFAJ-UHFFFAOYSA-N catechin Natural products OC1Cc2cc(O)cc(O)c2OC1c3ccc(O)c(O)c3 ADRVNXBAWSRFAJ-UHFFFAOYSA-N 0.000 description 1
- 235000005487 catechin Nutrition 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 229940045110 chitosan Drugs 0.000 description 1
- CWVRJTMFETXNAD-JUHZACGLSA-N chlorogenic acid Chemical compound O[C@@H]1[C@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-JUHZACGLSA-N 0.000 description 1
- 229940074393 chlorogenic acid Drugs 0.000 description 1
- FFQSDFBBSXGVKF-KHSQJDLVSA-N chlorogenic acid Natural products O[C@@H]1C[C@](O)(C[C@@H](CC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O FFQSDFBBSXGVKF-KHSQJDLVSA-N 0.000 description 1
- 235000001368 chlorogenic acid Nutrition 0.000 description 1
- 235000019219 chocolate Nutrition 0.000 description 1
- 229950001002 cianidanol Drugs 0.000 description 1
- BMRSEYFENKXDIS-KLZCAUPSSA-N cis-3-O-p-coumaroylquinic acid Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)cc2)[C@@H]1O)C(=O)O BMRSEYFENKXDIS-KLZCAUPSSA-N 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 229960005188 collagen Drugs 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 210000003298 dental enamel Anatomy 0.000 description 1
- 238000001784 detoxification Methods 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000015872 dietary supplement Nutrition 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 210000004709 eyebrow Anatomy 0.000 description 1
- 239000000576 food coloring agent Substances 0.000 description 1
- 239000005428 food component Substances 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 230000020169 heat generation Effects 0.000 description 1
- 235000012907 honey Nutrition 0.000 description 1
- 239000003906 humectant Substances 0.000 description 1
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 description 1
- 150000004715 keto acids Chemical class 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000002075 main ingredient Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 230000007659 motor function Effects 0.000 description 1
- 229920003052 natural elastomer Polymers 0.000 description 1
- 239000000974 natural food coloring agent Substances 0.000 description 1
- 229920001194 natural rubber Polymers 0.000 description 1
- 235000021062 nutrient metabolism Nutrition 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000009965 odorless effect Effects 0.000 description 1
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
- 229960002969 oleic acid Drugs 0.000 description 1
- 235000021313 oleic acid Nutrition 0.000 description 1
- 230000003239 periodontal effect Effects 0.000 description 1
- 201000001245 periodontitis Diseases 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 230000007505 plaque formation Effects 0.000 description 1
- 239000004302 potassium sorbate Substances 0.000 description 1
- 235000010241 potassium sorbate Nutrition 0.000 description 1
- 229940069338 potassium sorbate Drugs 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 235000007682 pyridoxal 5'-phosphate Nutrition 0.000 description 1
- 239000011589 pyridoxal 5'-phosphate Substances 0.000 description 1
- 229960001327 pyridoxal phosphate Drugs 0.000 description 1
- 235000008151 pyridoxamine Nutrition 0.000 description 1
- 239000011699 pyridoxamine Substances 0.000 description 1
- 235000008160 pyridoxine Nutrition 0.000 description 1
- 239000011677 pyridoxine Substances 0.000 description 1
- 230000003252 repetitive effect Effects 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- WXMKPNITSTVMEF-UHFFFAOYSA-M sodium benzoate Chemical compound [Na+].[O-]C(=O)C1=CC=CC=C1 WXMKPNITSTVMEF-UHFFFAOYSA-M 0.000 description 1
- 239000004299 sodium benzoate Substances 0.000 description 1
- 235000010234 sodium benzoate Nutrition 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 229960000790 thymol Drugs 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 description 1
- 235000005282 vitamin D3 Nutrition 0.000 description 1
- 239000011647 vitamin D3 Substances 0.000 description 1
- 229940021056 vitamin d3 Drugs 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
- 230000004580 weight loss Effects 0.000 description 1
- 208000016261 weight loss Diseases 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K15/00—Devices for taming animals, e.g. nose-rings or hobbles; Devices for overturning animals in general; Training or exercising equipment; Covering boxes
- A01K15/02—Training or exercising equipment, e.g. mazes or labyrinths for animals ; Electric shock devices ; Toys specially adapted for animals
- A01K15/025—Toys specially adapted for animals
- A01K15/026—Chewable toys, e.g. for dental care of pets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K6/00—Preparations for dentistry
- A61K6/15—Compositions characterised by their physical properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Environmental Sciences (AREA)
- Veterinary Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Public Health (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Physical Education & Sports Medicine (AREA)
- Dentistry (AREA)
- Epidemiology (AREA)
- Fodder In General (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
본 기술은 반려동물의 구강 및 치아 질환, 질병 (치아 우식증, 치석,치태,플라크 제거, 구취)을 예방함으로서 원인을 근본적으로 제거하기 위한 조성물과 놀이기구에 관한 것이다. The present technology relates to compositions and rides for fundamentally eliminating causes by preventing oral and dental diseases, diseases (tooth caries, plaque, plaque, plaque removal, bad breath) in companion animals.
최근 고령화와 1인 가구 증가에 따라 각종 동물이 사람들의 반려동물로서 대중화 되고 있다. 반려동물 시장은 2010년 이후 매년 20 ~ 25% 성장하고 있으며, 반려동물 용품의 소비역시 증가하고 있다. 치아 상태의 관리와 치주 질환 치료의 중요성이 점차 증진되고 있다. 반려견은 성장할 수록 강아지는 약 80%, 고양이는 약 70%가 다양한 형태의 치주 질환에 걸리는 것으로 알려져 있다. Recently, with the aging population and the increase of single-person households, various animals have become popular as companion animals. The companion animal market has grown 20 to 25% annually since 2010, and consumption of companion animal products has also increased. The importance of managing dental conditions and treating periodontal disease is gradually increasing. It is known that as dogs grow, about 80% of puppies and about 70% of cats develop various types of periodontal disease.
이러한 치주 질환은 치아 표면에 형성되는 치태 (입 안에 살고 있는 수많은 세균들이 타액 내의 특정 성분과 서로 엉겨 붙어서 형성), 치석 (시간이 경과함에 따라 치태가 굳어져 형성) 등에 의해 주로 야기되는 바, 반려동물의 건강과 직결되는 치주 질환의 예방과 구강 건강을 위한 보조제품의 필요성이 대두되고 있는 실정이다.This periodontal disease is mainly caused by plaque formed on the surface of the teeth (a large number of bacteria living in the mouth are stuck to each other with certain components in saliva), tartar (formed by hardening of the plaque over time), etc. There is a growing need for supplements for the prevention of periodontal disease and oral health that are directly related to animal health.
특히, 구강 및 치아 질환과 질병을 예방에 관해 진행되는 기존의 연구 활동은 제품의 성분에 치약 또는 다른 약제 성분을 포함하여 겔이나 치태, 치석을 제거하는 기술에 주로 초점이 맞추어져 있었으며, 추가적으로 치약이나 다른 약제 성분을 제품에 도포하여 제품이 반려동물의 저작시에 치아와 마찰하여 치태, 치석의 제거에 도움이 되며 천연 기능성 식품 성분을 섭취하면서 반려동물의 건강을 돌보는 것을 제시하고 있다. In particular, existing research activities conducted on oral and dental disease and disease prevention focused mainly on the technology of removing gel, plaque, and calculus, including toothpaste or other pharmaceutical ingredients in the components of the product, and additionally, toothpaste However, it is suggested that by applying other pharmaceutical ingredients to the product, the product rubs against the teeth when the pet is chewing, helps to remove plaque and plaque, and takes care of the health of the companion animal while consuming natural functional food ingredients.
본 발명에서는 반려동물의 구강 건강의 향상을 위해 반복적인 치아관리가 필요하나 바쁜 일상과 반려동물의 선호도 차이에 의하여 발생할 수 있는 관리의 부재와 어려움으로 생성되는 치석, 치태, 구취의 문제와 반려동물의 성장기에 발생하는 이갈이로 인한 가구등의 손상을 방지하고자 한다.In the present invention, repetitive dental care is required to improve the oral health of a companion animal, but problems of plaque, plaque, bad breath and companion animals generated due to lack of management and difficulties that can occur due to differences in the preferences of the busy animal and the companion animal In order to prevent damage to furniture, etc., caused by migrating during the growing season.
이에 본 발명은 천연유래 기능성 식품성분을 첨가한 덴탈 케어 겔을 내부에 포함한 다공성 실리콘 재질의 놀이기구로서 반려동물들에게 호기심을 자극하여 기존의 놀이의 기능과 건강보조식품의 기능을 결합한 조성물을 개발하게 되었다. Accordingly, the present invention is a porous silicone material play equipment containing a dental care gel containing natural functional food ingredients inside, which stimulates curiosity to companion animals and develops a composition that combines the functions of the existing play with the functions of a health supplement. Was done.
위에서 언급한 조성물과 수많은 돌기를 외부로 가지는 실리콘소재의 놀이기구는 반려동물의 저작 작용을 기초로 치태 및 치석 제거에 보다 효과적이며, 치아 및 치주의 질환을 유발하는 뮤탄스 균을 제거하는데 도움을 줄 수 있도록 하였다.The above-mentioned composition and rides made of silicone with numerous protrusions outside are more effective in removing plaque and plaque based on the chewing action of companion animals, and help to remove the mutans bacteria that cause diseases of teeth and periodontal periods. To give.
또한, 성장기의 반려동물의 이갈이를 돕기 위해 제품 내부에 뼈모양의 단단한 고무를 삽입하여 좀더 내구성을 더하며 이갈이로 인한 여러 제품들의 손상을 방지하고자 한다.In addition, in order to assist the migration of companion animals during the growing season, the bone-like hard rubber is inserted into the product to add more durability and to prevent damage to various products due to the migration.
본 발명의 실시 예에 따르면, 특유 형상의 (다공형 모양) 실리콘 재질의 놀이기구와 마찰작용에 따른 구강기능성 식품성분을 포함한 겔이 분사되어 반려동물이 스트레스를 받지 않고, 보조기구를 씹으면서 건강한 구강을 유지할 수 있도록 도움을 주며, 스스로 제거하지 못하는 치태 및 치석을 자연스럽게 제거하는 효과를 얻을 수 있다. According to an embodiment of the present invention, a gel having a unique shape (porous shape) silicone play equipment and oral functional food ingredients due to friction action is sprayed so that the companion animal is not stressed and healthy while chewing the auxiliary equipment. It helps to maintain the oral cavity and can effectively remove plaque and plaque that cannot be removed by themselves.
또, 본 발명에 따르면 겔에 포함된 기능성 식품 성분에 의해 반려동물의 항산화 효과, 장 운동 기능성 및 면역, 변비예방에 도움을 줄 수 있다. In addition, according to the present invention, the functional food component contained in the gel can help the pet's antioxidant effect, intestinal motor function and immunity, and prevent constipation.
도 1은 본 발명의 일 실시 예에 따른 반려동물용 구강건강 기능성 실리콘소재 놀이기구를 개략적으로 도시한다.
도 2는 실리콘 소재의 놀이기구 제품내에 투여된 구강 기능성 천연성분 겔 조성물이 실리콘소재의 놀이기구 내에서 외부압력이나 반려 동물의 저작시의 흐름을 나타내는 이미지이다.1 schematically shows an oral health functional silicone material play equipment for a companion animal according to an embodiment of the present invention.
Figure 2 is an image showing the flow of the oral functional natural ingredient gel composition administered in a silicone material ride product during external authoring or companion animal authoring in a silicone material ride.
전술한 바와 같이, 본 발명에 따른 애완동물의 구강 및 치아 보호 액상조성물은 자일리톨, 키토산, 비타민 B2, 비타민 B6, 비타민 D3, 알란토인, 글루콘산칼슘, 아미노산, 콜라겐으로 이루어진 군으로부터 하나 또는 그 이상 선택된 성분 을 필수 성분으로 함유하고, 밸런스 성분으로 물을 포함하며, 습윤제, 향료 또는 천연 식용 색소를 더욱 포함 할 수 있다.As described above, the liquid composition for oral and dental protection of pets according to the present invention is one or more selected from the group consisting of xylitol, chitosan, vitamin B2, vitamin B6, vitamin D3, allantoin, calcium gluconate, amino acid and collagen. It contains ingredients as essential ingredients, contains water as a balance ingredient, and may further contain a wetting agent, flavoring agent or natural food coloring.
한편, 본 발명에 포함되는 반려동물은 사람이 애완을 적으로 집에서 기르는 동물을 총칭하며, 대표적으로 개와 고양이, 이에 한정되는 것은 아니다. On the other hand, the companion animal included in the present invention generally refers to an animal that a person keeps at home as a pet, and is not limited to a dog and a cat.
본 발명에 포함되는 자일리톨은 키실리톨이라 부르기도 하며 키실로오스를 환원하여 얻는 5탄당 알콜로서 흰색의 결정 성 분말로무취이며 물에 잘 녹는다. 최근에 무설탕 과자나 초콜릿 등의 제조에 사되는 신규 감미료 중의 하나이며 구강 미생물에 의해 발효하지 않기 때문에 치아우식증을 일으키지 않는다. 설탕의 0.9∼1.0배 정도의 단맛을 가지며 청량감이있다. 독성은 거의 없고(포도당과 같은 수준) 과다 섭취할 경우에는 설사를 하는 수가 있으며 1g당 3.57kcal의 열량을 발 생한다. 또한 치균의 성장을 억제해 프라그의 형성을 감소시키고 프라그에서 산의 생산을 억제하기도 하며 법랑질에서 광물질이 이탈하는 현상을 방지하는 작을 하여 준다. Xylitol, which is included in the present invention, is also called xylitol and is a five-carbon alcohol obtained by reducing xylose. It is a white crystalline powder, odorless and soluble in water. Recently, it is one of the new sweeteners used in the production of sugar-free confectionery and chocolate, and does not cause dental caries because it is not fermented by oral microorganisms. It has a sweetness of 0.9 to 1.0 times that of sugar and has a refreshing feeling. It has little toxicity (same level as glucose) and can cause diarrhea when consumed excessively, producing 3.57 kcal of calories per gram. In addition, it inhibits the growth of tooth bacteria, reduces the formation of plaque, suppresses the production of acid in the plaque, and works to prevent the phenomenon of mineral separation from enamel.
본 발명에 있어서, 상기 자일리톨의 사량은 10 내지 50중량부가 바람직한데, 10중량부 미만이면 본래 적하는 약리 효과가 발휘 될 수 없으며, 50중량부를 초과하면 과다한 단맛과 열량발생 및 설사를 초래하는 경향이 있다. In the present invention, the amount of xylitol used is preferably 10 to 50 parts by weight, and if less than 10 parts by weight, the inherent pharmacological effect cannot be exerted, and when it exceeds 50 parts by weight, tendency to cause excessive sweetness and heat generation and diarrhea There is this.
벌꿀 추출물인 프로폴리스의 강력한 항균 작용을 통해 구강 질환을 억제할 수 있다. Propolis, a honey extract, can suppress oral diseases through its strong antibacterial action.
공개번호 특1996-0003712에는 프로폴리스를 함유한 치약조성물에 관한 것으로 프로폴리스를 0.01 내지 5.0중량%, 바람직하게는 0.1 내지 1.0% 포함하는 치약조성물이 기재되어 있고, 공개번호 특1997-0009782호에는 프로폴리스가 함유된 치약조성물에 관한 것으로 일반치약조성물에 프로폴리스의 알코올성 추출물 및 수용성 추출물을 5~15중량% 포함한 것이 있다Publication No. 1996-0003712 relates to a toothpaste composition containing a propolis, and a toothpaste composition containing 0.01 to 5.0% by weight of propolis, preferably 0.1 to 1.0%, is disclosed, and Publication No. 1997-0009782 Regarding toothpaste composition containing propolis, there are 5~15% by weight of alcohol extract and water-soluble extract of propolis in general toothpaste composition.
녹차 추출물은 항암효과, 노화 억제, 성인병 예방, 해독작용, 충치 예방 및 입냄세 제거 효과를 가지는 것으로 알려져 있으며. 주요 성분으로 카테킨, 클로로겐산, 니아신, 올레산, 티몰등이 함유 되어있다.Green tea extract is known to have anti-cancer effect, anti-aging, adult disease prevention, detoxification, tooth decay prevention and bad breath removal. The main ingredients are catechin, chlorogenic acid, niacin, oleic acid, and thymol.
특히 녹차 추출물은 호르면 관련성 치주염을 유발하며 복합 감염을 촉진하는 역할을 하는 세균인 Prevotella intermedia에 대한 효과적인 항균 작용이 보고되어 있으며, 천연 방부제로서의 기능도 보고되어 있다.In particular, green tea extract has been reported to have an effective antimicrobial effect against Prevotella intermedia, a bacterium that induces related periodontitis and promotes complex infections, and also functions as a natural preservative.
비타민 B6은 비타민 B6의 효력을 나타내는 든 물질을 총칭하는 이름으로서 피리독신(pyridoxine), 피리독살 (pyridoxal) 및 피리독사민(pyridoxamine)이 여기에 속한다. 생체내에서 비타민 B6는 피리독살이 한 분자의 인산과 결합 한 형태인 피리독살인산으로 되어 영양소대사에 조효소로 작한다. 특히 아미노산으로부터 다른 케토산으로의 아미노기 의 전이, 황을 함유하는 아미노산으로부터 SH군의 제거, 아미노산으로부터 이산화탄소의 제거 및 아미노기의 제거 등 생 체 내 반응의 효소에 대한 조효소로 아미노산과 단백질대사에 광범위하게 작한다. 결핍증세는 니코틴산이나 비타민 B2 결핍증세와 비슷하다. 즉, 초기에는 눈 주위·눈썹·입가장자리·혀의 염증으로 시작하여 현기증·구토·체중감소·정신불안·빈 혈·신석·경련 등의 증세로 진행된다.Vitamin B6 is a generic name for all substances that have the effect of vitamin B6, and includes pyridoxine, pyridoxal, and pyridoxamine. In vivo, vitamin B6 becomes pyridoxal phosphate, a form in which pyridoxal is combined with a molecule of phosphoric acid, and acts as a coenzyme in nutrient metabolism. In particular, it is a coenzyme for enzymes in reactions in vivo, such as the transfer of amino groups from amino acids to other keto acids, the removal of SH groups from amino acids containing sulfur, the removal of carbon dioxide from amino acids, and the removal of amino groups. It works. The deficiency is similar to that of nicotinic acid or vitamin B2. That is, in the beginning, it starts with inflammation around the eyes, eyebrows, edges, and tongue, and progresses to symptoms such as dizziness, vomiting, weight loss, anxiety, anemia, kidney stones, and cramps.
이와 같이, 본 발명의 조성물은 치아 및 구강점막의 영양공급원으로 비타민 B6 및/또는 비타민 B2을 포함한다. As such, the composition of the present invention includes vitamin B6 and/or vitamin B2 as a nutrient supply source for teeth and oral mucosa.
본 발명에 따르면, 상기 조성물은 구강 점막내 보습의 적으로 솔비톨, 글루코스, 글리세린 및 이들의 혼합물로 이루어 진 군으로부터 선택된 습윤제를 더욱 포함할 수 있다. 상기 습윤제의 사량은 구강 점막보호 및 건조증 예방의 적으로 상기 조성물 100중량부에 대하여 1 내지 20중량부가 바람직하다. 또한, 본 발명의 조성물은 식 색소 및/또는 식향료 를 더욱 포함하여 색상 및 냄새로 애완동물의 유도할 수 있다.According to the present invention, the composition may further include a humectant selected from the group consisting of sorbitol, glucose, glycerin and mixtures thereof as a moisturizing enemy in the oral mucosa. The amount of the wetting agent is preferably 1 to 20 parts by weight based on 100 parts by weight of the composition for the purpose of protecting the oral mucosa and preventing dryness. In addition, the composition of the present invention may further include a food coloring and/or a flavoring agent to induce pets with color and smell.
한편, 본 발명의 조성물은 방부제로는 안식향산나트륨, 소르빈산칼륨 및 이의 혼합물을 선택적으로 사할 수 있으며, 점 도조정을 위하여 셀룰로오스검, 산탄검, 하이드록시에칠셀룰로오스 및 이의 혼합물을 선택적으로 사할 수 있으며, pH조 정제를 더욱 포함할 수 있는데 이들 두는 식이성을 전제로 하여야 한다. Meanwhile, the composition of the present invention may selectively use sodium benzoate, potassium sorbate, and a mixture thereof as a preservative, and selectively use cellulose gum, xanthan gum, hydroxyethyl cellulose, and a mixture thereof for viscosity adjustment. , pH tank tablets may be further included, these two should be premised on the diet.
전술한바와 같은 조성물을 실리콘 소재의 다공성 구조물에 투여하여 반려동물이 저작시 실리콘소재의 여러 구멍을 통해 흘러나오게 되며, 실리콘 소재의 복수의 외부 돌기와 함께 반려동물의 치아와 마찰되게 되며 이를 통해 치태와 치석을 제거하고자 한다.When the composition as described above is administered to a porous structure made of silicone material, when the animal is chewed, it flows through various holes in the silicone material, and it rubs against the pet's teeth along with a plurality of external protrusions of the silicone material, through which plaque and plaque I want to remove calculus.
또한, 중,대형견의 경우 구강 구조가 크며 성장시에 이갈이를 위해 단단한 부분에 이를 가는 경우가 있어 집안의 가구나 벽에 상처를 남기는 경우를 방지하지 위하여 다.In addition, in the case of medium and large dogs, the oral cavity structure is large, and when it grows, it may go to the hard part for migrating.
본 제품 내에 경도가 단단한 뼈모양의 천연 고무 막대를 삽입하여 반려동물의 성장시, 이갈이로 인하여 발생하는 문제 역시 해결하고자 한다. We also try to solve the problem caused by molting during the growth of companion animals by inserting a bone-shaped natural rubber rod with hard hardness into this product.
Claims (3)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020180163113A KR20200074569A (en) | 2018-12-17 | 2018-12-17 | Dental functional natural gel composition for companion animal and Dental functional silicone material play equipment |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020180163113A KR20200074569A (en) | 2018-12-17 | 2018-12-17 | Dental functional natural gel composition for companion animal and Dental functional silicone material play equipment |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20200074569A true KR20200074569A (en) | 2020-06-25 |
Family
ID=71400042
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020180163113A Ceased KR20200074569A (en) | 2018-12-17 | 2018-12-17 | Dental functional natural gel composition for companion animal and Dental functional silicone material play equipment |
Country Status (1)
| Country | Link |
|---|---|
| KR (1) | KR20200074569A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220087224A1 (en) * | 2019-02-15 | 2022-03-24 | John Henry Gallagher | Oral Hygiene Appliance |
| KR20230075961A (en) | 2021-11-23 | 2023-05-31 | 주식회사 어바웃펫 | Chewing brush for pet |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20030027292A (en) | 2001-09-28 | 2003-04-07 | 윤철기 | A device for pasting and drying a plurality of a thin paper in a form of a layer |
| KR101009987B1 (en) | 2010-05-26 | 2011-01-21 | 주식회사 포켄스 | Dental gum for pets |
| KR20150016199A (en) | 2012-05-25 | 2015-02-11 | 파나소닉 주식회사 | Image encoding method, image encoding device, image decoding method, image decoding device, and image encoding/decoding device |
| KR20160029511A (en) | 2014-09-05 | 2016-03-15 | 에스케이하이닉스 주식회사 | Stack package and system in package including the same |
| KR20170018500A (en) | 2015-08-10 | 2017-02-20 | 박종용 | Flaming Coal Liquefying Device and Methode of Oil Extracting by Thermal Cracking from Flaming Coal |
-
2018
- 2018-12-17 KR KR1020180163113A patent/KR20200074569A/en not_active Ceased
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20030027292A (en) | 2001-09-28 | 2003-04-07 | 윤철기 | A device for pasting and drying a plurality of a thin paper in a form of a layer |
| KR101009987B1 (en) | 2010-05-26 | 2011-01-21 | 주식회사 포켄스 | Dental gum for pets |
| KR20150016199A (en) | 2012-05-25 | 2015-02-11 | 파나소닉 주식회사 | Image encoding method, image encoding device, image decoding method, image decoding device, and image encoding/decoding device |
| KR20160029511A (en) | 2014-09-05 | 2016-03-15 | 에스케이하이닉스 주식회사 | Stack package and system in package including the same |
| KR20170018500A (en) | 2015-08-10 | 2017-02-20 | 박종용 | Flaming Coal Liquefying Device and Methode of Oil Extracting by Thermal Cracking from Flaming Coal |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220087224A1 (en) * | 2019-02-15 | 2022-03-24 | John Henry Gallagher | Oral Hygiene Appliance |
| US11730144B2 (en) * | 2019-02-15 | 2023-08-22 | Clean Bite, Llc | Oral hygiene appliance |
| KR20230075961A (en) | 2021-11-23 | 2023-05-31 | 주식회사 어바웃펫 | Chewing brush for pet |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102026617B (en) | For preventing the confection product containing algae of oral cavity-infected tooth | |
| US6503483B2 (en) | Dental formulation | |
| CN102548526B (en) | Dentifrice composition | |
| CN106963662B (en) | Color-changing toothpaste for children and preparation method and application thereof | |
| US8435499B2 (en) | Toothpowder composition containing wheat flour and bamboo salt | |
| KR102196120B1 (en) | Toys for pets plaque removal | |
| US20090269288A1 (en) | Black pearl toothpaste | |
| CN101321537A (en) | Confectionary compositions with magnolia bark extract | |
| CN101939057A (en) | Use of cationic surfactants for the protection against tooth erosion | |
| US4022879A (en) | Oral hygiene product for animals | |
| CN105997615A (en) | Natural and edible children's mouthwash and preparation method thereof | |
| KR20200074569A (en) | Dental functional natural gel composition for companion animal and Dental functional silicone material play equipment | |
| US6071500A (en) | Breath spray with tooth decay and halitosis prevention characteristics | |
| US20050139167A1 (en) | Chewable toy for animals | |
| KR100513117B1 (en) | Toy for protecting an oral cavity and a teeth of a pet animal | |
| EP1379223A1 (en) | Dental formulation | |
| US11723847B2 (en) | Dual component oral composition for enhancing remineralization of teeth | |
| CN107441019B (en) | Toothpaste for pets and preparation method thereof | |
| DE10258659B4 (en) | Use of Salvadora persica in oral and dental care for pets and pets | |
| WO2004010962A1 (en) | Liquid composition for protecting oral cavities and teeth of pet animals and use thereof in plaything for pet animals | |
| KR20070043174A (en) | Toothpaste composition containing mastic | |
| US20240148619A1 (en) | Dual component oral composition for enhancing remineralization of teeth | |
| KR102247672B1 (en) | Companion animal dental functional play | |
| KR102365265B1 (en) | Mouthwash composition for animals and manufacturing method thereof | |
| CN110801417A (en) | Toothpaste for children |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 20181217 |
|
| PA0201 | Request for examination | ||
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20200602 Patent event code: PE09021S01D |
|
| PG1501 | Laying open of application | ||
| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
Patent event date: 20200903 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 20200602 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |
|
| E601 | Decision to refuse application | ||
| PE0601 | Decision on rejection of patent |
Patent event date: 20200918 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 20200602 Comment text: Notification of reason for refusal Patent event code: PE06011S01I |