KR20160003090U - Apparatus for Collecting vital tissue - Google Patents

Abstract

The present invention provides a tissue harvesting device including a collecting part and a handle part. Unlike conventional biopsy devices, tissue collection devices of this invention can be useful for collecting and storing large amounts of animal tissue required for meat quality evaluation. In addition, the apparatus for tissue harvesting of the present invention can be applied to the sampling of tissue samples of all mammals, including human specimen or lesion tissue isolated in vitro.

Description

Apparatus for collecting vital tissue [0002]

This invention relates to an apparatus for tissue harvesting. More particularly, the present invention relates to an apparatus for sample-tissue-collecting from fresh meat.

Tissue biopsy, also called biopsy or biopsy, is widely used to diagnose the presence or absence of a disease by collecting a part of the body tissue and then examining it with a microscope or the like. Such a tissue biopsy can be applied not only to humans but also to all living organisms. Especially for livestock such as cattle, pigs, horses, sheep, etc., tissue biopsy is used to evaluate the meat quality.

Biopsy samples used in tissue biopsy can be obtained using a variety of devices. A biopsy device used in humans can be fully operable by a user using a single hand as a single insert to capture one or more biopsy samples from a human. Some biopsy devices may be tethered to a vacuum module and / or a control module for delivery of fluids (e.g., compressed air, saline, air, vacuum, etc.) or delivery of power. Needle biopsy is the most widely used method of biopsy applied to humans. This needle biopsy is a step of inserting a test needle made of double structure of a call part and an acupuncture part into the body to extract the body tissue of the lesion . Thus, the tissue biopsy device that can be used in humans is intended to perform a simple biopsy without a skin incision with a thin needle, and it is difficult to use it in tissue sampling for quality evaluation of slaughtered livestock animals.

That is, tissue biopsy devices available to humans are sold as disposable products such as sterilized syringes, and since only a small amount of tissue samples can be sampled, tissue samples required for meat quality evaluation can be quickly obtained from slaughtered animals and stored It is not possible to use a tissue biopsy device which can be used for the human. In general, biopsies in slaughtered animals are made in large quantities, and tissue samples taken from each individual must be stored for a certain period of time.

For example, the Livestock Products Quality Assurance Institute is required to store tissue samples for a certain period of time to evaluate the quality of livestock products. The equipment for dealing with these laboratory animal tissue specimens includes a medical tissue specimen for histopathology examination and a cassette for laboratory test and plant study tissue specimen. This cassette is a synthetic resin storage case for treating and storing tissue specimens. A sample packaged in an oil film is stored in the rectangular storage case. However, such a cassette has a disadvantage in additionally requiring a step of sampling the tissue separately. Since each cassette requires a large volume of sampler depending on the type and number of slaughtered cattle and the number and location of slaughtered cattle, It was required to secure space for

Therefore, the inventors developed a tissue harvesting device capable of sampling and storing a large amount of tissue from slaughtered livestock, which is easier to sample in tissue than conventional instruments and is designed to save storage space.

Numerous papers and patent documents are referenced and cited throughout this specification. The disclosures of the cited papers and patent documents are incorporated herein by reference in their entirety to state the level of the art to which this invention pertains and the contents of this invention are more clearly described.

In view of the difficulty in collecting the animal tissues required for meat quality assessment using existing tissue harvesting devices, the present inventors have been able to quickly collect tissue suitable for meat quality evaluation from a large number of individuals and save storage space And to develop a tissue harvesting device. As a result, a device capable of collecting tissue of an animal by forming a plurality of grooves capable of accommodating a tissue sample collected from the living tissue at the fore-end of the conical collection unit has been developed.

Therefore, the purpose of this design is to provide an organization for tissue harvesting.

Other objects and advantages of the present invention will become more apparent from the following detailed description of the invention, the claims and drawings.

According to one aspect of the present invention, the present design provides a tissue harvesting device that includes:

(a) a horn-like collecting portion for scratching a surface of a living tissue to collect a tissue sample, wherein a fore end of the horn-like collecting portion is provided with a plurality of Grooves are formed, the cross section of the collecting section is elliptical, and a groove is formed to receive a tissue sample in a groove in the long axis direction of the ellipse; And

(b) a bar shaped handle formed on one side of the collecting portion, for handling the collecting portion.

In view of the difficulty in collecting the animal tissues required for meat quality assessment using existing tissue harvesting devices, the present inventors have been able to quickly collect tissue suitable for meat quality evaluation from a large number of individuals and save storage space And to develop a tissue harvesting device. As a result, a device capable of collecting tissue of an animal by forming a plurality of grooves capable of accommodating a tissue sample collected from the living tissue at the fore-end of the conical collection unit has been developed.

The tissue sampling device of the present invention includes a horn-shaped " collecting part (100) " having a plurality of grooves (110) capable of receiving a tissue sample collected from a living tissue at a fore- It is a device that can scratch the surface of the tissue and collect the tissue sample. The "horn shape" means a shape in which the diameter decreases toward one end of the collecting part.

The tissue sample housed in the groove of the collecting part may be stored as it is, or may be provided with a cap 300 or an external cover that can house the collecting part.

The tissue harvesting apparatus of the present invention can be applied to all organisms that can utilize the Needle Biopsy method and can be applied to collecting tissue samples of all mammals, including human specimen or lesion tissue isolated in vitro, Preferably to fresh meat of livestock such as cattle, pigs, horses, sheep, rabbits, dogs and the like. As used herein, the term " living tissue " is used interchangeably with a tissue sample of a mammal.

According to the present invention, the apparatus for tissue collection of this invention comprises (i) a collection unit; And (ii) a handle.

Hereinafter, the mechanism for tissue collection of the present invention will be described in detail.

Configuration (a): Collecting unit (100)

The tissue sampling device of the present invention includes a generally conical collection portion for scratching the surface of a living tissue to collect a tissue sample. A plurality of grooves 110 are formed at the fore end of the conical collection unit to receive a tissue sample collected from the living tissue.

The collecting section may have an elliptical, circular or polygonal cross section, and according to the present invention, the cross section of the collecting section is elliptical. On the other hand, when the cross section of the collecting part is elliptical, grooves may be formed to accommodate the tissue sample in the grooves of the elliptical long axis direction. When sampling the tissue in the long axis direction of the collection part, the tissue surface can be scratched with a wider area.

According to the present invention, the overall shape of the collecting part is a substantially conical shape and a shape in which the width (or radius) becomes narrower toward the apex or the distal end of the conical shape.

The number, spacing, and size of the grooves that can be formed in the collecting part are not limited. For example, the grooves may be formed to have a certain interval and size as in the apparatus for collecting tissue of the present invention, .

According to the present invention, a connecting groove can be formed on one side of the collecting part so as to be connectable with the handle 200. In this case, the connecting groove 210 of the handle is inserted into the connecting groove 120 of the collecting part. . Meanwhile, the collecting part and the handle may be integrally formed.

Configuration (b): Handling unit (200)

The apparatus for collecting tissue of the present invention is connectable or attachable to one side of the collecting part and includes a bar shaped handle for handling of the collecting part.

The handle may be integrally formed with the collecting part or may be detachable from the collecting part. When the handle portion is formed in a detachable manner, the handle portion and the collecting portion can be engaged and disengaged by a fitting method or a cutting method. For example, in the case of the fitting type, the handle and the collecting portion may be formed with threads or grooves that can be engaged with each other. In case of the cutting method, a force of a predetermined magnitude is applied on the boundary line between the handle and the collecting portion, A straight groove can be formed. Alternatively, the handle portion and the collecting portion may be connected using a separate connecting member.

The handle may be a rectangular parallelepiped or a cylindrical shape rather than a cylindrical shape or a cylindrical shape having a concave central portion (concave portion) 220 rather than a cylindrical shape. For example, when the cross section of the collecting part is elliptical, the tissue surface is scratched by the surface in the major axis direction. In order to efficiently transmit the force in the long axis direction, the shape of the handle is also formed in a concave or flat shape Reference).

Meanwhile, the apparatus for collecting tissue of the present invention may further include a removable cap-like cap 300 having the collection unit built therein. The cap is used to cover the collecting part and is useful when a sample needs to be stored for a certain period of time. The distal end of the cap may be formed with an exposure hole 310 through which air can enter and there is no particular limitation on the number of exposed holes. According to the present invention, the plurality of exposure holes may be formed. The moisture contained in the tissue sample is evaporated through the exposed hole and dried. Conventionally, in order to store a tissue sample, a drying process for removing water contained in the tissue has been essential. However, the apparatus for collecting tissue of the present invention is more useful because it can be dried together with storage.

Meanwhile, the cap may be formed in a shape that the width becomes narrower toward the distal end (concave portion 320), in order to facilitate operation when the cap is detached.

When the cap is coupled to the collecting part, a space is required to be large enough to accommodate the tissue sample in the inside of the cap other than the space of the collecting part itself, so that the diameter of the cap is made larger than the diameter of the collecting part.

Meanwhile, the apparatus for collecting tissues of the present invention may be fabricated as a multifunctional or disposable material. The material may be made of a biocompatible alloy or a heat-resistant synthetic resin. Examples thereof include thermoplastic resins (polycarbonate, polystyrene, polyvinyl chloride, polyethylene, (Phenol resin, amino resin, epoxy resin) or ABS resin (acrylonitrile-butadiene-styrene resin). The above-described synthetic resin is heat-resistant at a temperature of about 100 캜 or lower.

In the case where the tissue harvesting device of the present invention is manufactured in a disposable form, the collecting portion, the handle portion and the cap may be all made of synthetic resin, or the collection portion may be made of a biocompatible alloy.

The features and advantages of the present invention are summarized as follows:

(a) The present invention provides a tissue harvesting device including a collecting part and a handle part.

(b) Unlike conventional biopsy devices, tissue harvesting devices of this invention can be useful for collecting and storing large amounts of animal tissue required for meat quality evaluation.

(c) The apparatus for tissue harvesting of the present invention may be applied to the sampling of tissue samples of all mammals, including human specimens or lesion tissues separated from the body.

Fig. 1 shows a perspective view of a tissue harvesting device according to the present invention.
2A shows a perspective view of a collecting part in a tissue collecting instrument according to the present invention. The cross section of the collecting portion in Figure 2a is elliptical.
FIG. 2B shows a front view of the collecting part in the tissue sampling apparatus according to the present invention. FIG. The cross section of the collecting portion of Fig. 2B is an elliptical shape, showing a long axis or a major radius direction.
2C shows a side view of the collecting part in the tissue collecting instrument according to the present invention. The cross section of the collecting portion in Fig. 2 (c) is elliptical in shape, showing a short axis or a radial direction.
FIG. 3A shows a front view of the handle in the tissue sampling device according to the present invention. FIG. 3A, grooves are formed in the upper part of the handle for engaging the catching part and the handle part.
FIG. 3B shows a side view of the grip portion in the tissue sampling device according to the present invention. FIG. The handle of FIG. 3B has a concave middle portion, which facilitates handling, and the groove formed in the handle and the groove formed in the collecting portion can be fitted to each other.
4A is a perspective view of a cap in a tissue sampling apparatus according to the present invention.
Figure 4b shows a front view of the cap in a tissue harvesting device according to the present invention. The cap of the collecting portion of Fig. 4B is substantially cylindrical in shape and has a plurality of exposure holes for air in and out.
Figure 4c shows a side view of the cap in a tissue harvesting device according to the present invention. The shape becomes narrower toward the distal end of the cap.

Hereinafter, the present invention will be described in more detail by way of examples. It will be apparent to those skilled in the art that these embodiments are only for describing the present invention in more detail and that the scope of the present invention is not limited by these embodiments in accordance with the gist of the present invention .

Example

The apparatus for collecting tissue of the present invention includes a collecting part 100 having a substantially conical shape, a handle 200 having a substantially bar shape, and a cap 300 having a substantially cylindrical shape (see FIG. 1). The handle is formed on one side of the collecting part in the axial direction, and the cap has a space formed therein for accommodating the collecting part and the tissue sample therein.

A plurality of grooves 110 are formed at the fore end of the conical shape collecting part to receive a tissue sample collected from the living tissue.

The collector may have an elliptical cross section and a groove may be formed to receive a tissue sample in a groove in the long axis direction of the ellipse. When sampling the tissue in the long axis direction of the collection part, the tissue surface can be scratched with a wider area.

The overall shape of the collecting part is a substantially conical shape and has a shape in which the width (or radius) becomes narrower toward the apex or distal end of the conical shape, so that when the cap is used to accommodate or store the tissue sample Sufficient space can be secured.

At the distal end of the collecting part, 4-5 grooves are formed at regular intervals. When the living tissue is scratched by the collecting part, the tissue is accommodated in the concave part of the groove.

A connecting groove is formed at one side of the collecting part so as to be connected to the handle 200 so that the connecting groove 210 of the handle is fitted and coupled to the connecting groove 120 of the collecting part 1).

On the other hand, the apparatus for collecting tissue of the present invention includes a bar-shaped handle for connection with or coupling with one side of the collecting part and for handling of the collecting part. The handle may be integrally formed with the collecting part or may be detachable from the collecting part. When the handle portion is formed in a detachable manner, the handle portion and the collecting portion can be engaged and disengaged by a fitting method or a cutting method. For example, in the case of the fitting type, the handle and the collecting portion may be formed with threads or grooves that can be engaged with each other. In case of the cutting method, a force of a predetermined magnitude is applied on the boundary line between the handle and the collecting portion, A straight groove can be formed. Alternatively, the handle portion and the collecting portion may be connected using a separate connecting member.

The grip portion is a portion in which pressure is to be transmitted to the collecting portion at the time of tissue sampling, and is a rectangular parallelepiped shape having a concave central portion (concave portion) 220 rather than a complete rectangular parallelepiped. For example, when the cross section of the collecting part is elliptical, the tissue surface is scratched by the surface in the major axis direction. In order to efficiently transmit the force in the long axis direction, the shape of the handle is also formed in a concave or flat shape Reference).

The apparatus for collecting tissue according to the present invention includes a removable cap-like cap 300 having the collecting part built therein. The cap is used as a cover for covering the collecting part, and when the sample needs to be stored for a predetermined period of time, the sample can be preserved from contamination of the external environment. A plurality of exposure holes 310 are formed in the distal end of the cap to allow air to flow in and out.

Meanwhile, the cap may be formed in a shape that the width becomes narrower toward the distal end (concave portion, 320). The concave portion is useful when manually detaching the cap.

When the cap is coupled to the collecting part, a space is required to be large enough to accommodate the tissue sample outside the space of the collecting part itself, so that the diameter of the cap is made larger than the diameter of the collecting part.

The material for the tissue harvesting apparatus of the present invention may be made of thermoplastic resin, polycarbonate, polystyrene, or an ABS resin (acrylonitrile-butadiene-styrene resin) which is a new material.

Having described specific portions of the invention in detail, those skilled in the art will appreciate that these specific embodiments are merely preferred embodiments and that the scope of the present invention is not limited thereto. Accordingly, the actual scope of the present invention will be defined by the appended claims and their equivalents.

The collecting unit (100)
Grooves 110
A connecting groove 120,
In the handle 200,
Connecting groove 210,
In the recess 220,
In the cap 300,
Exposure Balls (310)
The concave portion 320,

Claims (5)

Equipment for tissue harvesting, including:
(a) a horn-like collecting portion for scratching a surface of a living tissue to collect a tissue sample, wherein a fore end of the horn-like collecting portion is provided with a plurality of Grooves are formed, the cross section of the collecting section is elliptical, and a groove is formed to receive a tissue sample in a groove in the long axis direction of the ellipse; And
(b) a bar shaped handle formed on one side of the collecting portion, for handling the collecting portion.
The tissue harvesting device according to claim 1, wherein the handle is detachable from the collecting part.
The tissue harvesting device according to claim 1, wherein the tissue harvesting mechanism further comprises a removable cylindrical cap with the collecting part embedded therein.
4. The apparatus for collecting tissue according to claim 3, wherein the cap is formed with an exposure hole through which air can enter and exit.
4. The apparatus for collecting tissue according to claim 3, wherein the cap has a shape narrower toward the distal end.

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