KR20120106016A - Natural fermentation hair restorer and the manufacturing method thereof - Google Patents

Abstract

The present invention relates to a method for producing a composition such as natural fermented hair repellent 숙, Sukji sulfur, red ginseng, garlic, wolfberry, black soybean, etc., in the method for producing a hair repellent, after sterilizing the pulverized 톳 powder, 6 months at 35 ℃ 톳 fermentation extract manufacturing step of extracting by fermentation; After the sterilization treatment of Sukjihwang, red ginseng, garlic, wolfberry and black soybeans, fermented extract of the first herbal fermented extract prepared by fermentation for 3 months at 35 ℃; And a second herbal fermentation extract manufacturing step of fermenting the first fermented Sookji sulfur fermentation extract, gooseberry fermentation extract, garlic fermentation extract, goji berry fermentation extract and black soybean fermentation extract to ferment for 2 months at 30 ° C. for 2 months or more. It is characterized by.

Description

Natural fermentation hair restorer composition and manufacturing method thereof

The present invention relates to a natural hair regrowth composition and a method for producing the same, and more particularly, to a natural fermentation hair regrowth composition and a method for producing the same having an effect of improving the hair loss by using a fermented extract of fermented herbs and various herbal ingredients. .

The main causes of hair loss include the action of dihydrotestosterone (DHT), a waste product of male hormones, irritable scalp, fat-soluble scalp, decreased hair root blood flow, and stress. Therefore, hair removal can be promoted by eliminating such a cause.

On the other hand, a minoxidil-containing agent is a hair regrowth agent mainly used in the treatment and prevention of such alopecia. Minoxidil was a high blood pressure treatment drug developed for the purpose of lowering blood pressure, and as a side effect of use, hair growth phenomenon is now widely used as a hair growth agent.

Although the exact mechanism of the hair growth action of minoxidil is not known, it is generally known to promote hair growth by nourishing hair roots by increasing blood flow through vasodilation effect. However, the minoxidil has a problem that the fine hair is thickened, and when the use thereof is stopped, the effect is also stopped and returned to its original state.

In addition to minoxidil, a composition containing ginkgo extract and red ginseng extract as a hair regrowth agent (Korean Patent Publication No. 2000-38214), a composition containing an extract of orchid family (Korean Patent No. 157667), flour and mussel powder such as mung bean powder and soybean powder Etc. (Korean Patent No. 260673), and compositions containing juices such as baekbaekpi and baekyeop and ginger used in herbal medicine (Korean Patent No. 201589), etc. are known, but there is still a certain prevention of hair loss and hair growth Product development is not active.

In addition, these conventional hair regrowth agents do not show a significant effect on hair growth substantially because they have an improvement function for only one type of causes of the above-mentioned various hair loss.

The purpose of the present invention is to improve the fat-soluble scalp by inhibiting DHT action, a waste product of male hormones, inhibiting hypersensitivity reactions of the scalp, and inhibiting the excessive release of lipids of the scalp by using extracts fermented with bovine and various herbal ingredients. It is to provide a natural fermentation hair regrowth composition for promoting hair growth and a method for producing the same.

In addition, an object of the present invention is a natural fermented hair regrowth composition and method for producing the same, which promote hair growth by promoting the hair root activity by improving the amount of blood flow in the capillaries and the relaxation of the scalp tissue by using the extract fermented with 톳 and various herbal ingredients In providing.

In order to achieve the above object, the natural fermentation hair regrowth composition according to the present invention, in the composition of the hair regrowth, after the sterilization treatment of pulverized powder 톳, 추출물 fermented extract extracted by fermentation for at least 6 months at 35 ℃; Sukji sulfur fermented extract extracted by fermentation for three months after the sterilization of succinct; After sterilizing the ginseng, fermented extract extracted by fermentation for 3 months at 35 ℃; After the sterilization of garlic, garlic fermented extract extracted by fermentation for 3 months at 35 ℃; After sterilization of the wolfberry, fermented extract extracting fermented for 3 months at 35 ℃; And black soybean fermented extract extracted by fermentation at 35 ° C. for 3 months after sterilizing the black soybean; wherein, the ripening sulfur fermented extract, red ginseng fermented extract, garlic fermented extract, wolfberry fermented extract and black soybean fermented extract are mixed It is characterized in that the secondary fermentation for at least 3 months at 30 ℃.

At this time, the fermented extract is characterized in that the alginic acid is separated by freeze precipitation at -20 ℃ or less.

On the other hand, the method of fermenting each fermentation extract is characterized in that the fermentation tank is added to each fermented raw material with water, added to 5 to 10% by weight, and then fermented by inoculating Saccharomyces.spp strain.

In addition, the composition is characterized in that it further comprises aloe extract as a natural emulsifier olive liquid, vitamins as hair root cell metabolism promoter, scalp moisturizer.

In order to achieve the above object, the production method of the natural fermentation hair regrowth composition according to the present invention, in the production method of the hair regrowth, after the sterilized treatment of the ground powder 톳 fermentation, which is extracted by fermentation for 6 months or more at 35 ℃ Extract preparation step; After the sterilization treatment of Sukjihwang, red ginseng, garlic, wolfberry and black soybeans, fermented extract of the first herbal fermented extract prepared by fermentation for 3 months at 35 ℃; And a second herbal fermentation extract manufacturing step of fermenting the first fermented Sookji sulfur fermentation extract, gooseberry fermentation extract, garlic fermentation extract, goji berry fermentation extract and black soybean fermentation extract to ferment for 2 months at 30 ° C. for 2 months or more. It is characterized by.

At this time, the 톳 fermentation extract manufacturing step, the step of freezing precipitation the fermented 톳 extract at -20 ℃ below to separate the alginic acid; characterized in that it further comprises.

On the other hand, the primary herbal fermentation extract manufacturing step, the step of washing each raw material to remove impurities; Sterilizing the washed raw materials and then cooling them at room temperature; And injecting the sterilized raw materials into the fermenter together with water, and adding 5 to 10% by weight, inoculating the Saccharomyces.spp strain and fermenting the same.

In addition, the secondary herbal fermentation extract manufacturing step, the step of mixing each of the primary fermentation extract into a fermenter; Removing the microorganism from the fermented extract of the second fermentation and removing the alcohol component; And purifying the fermented extract by filtration with a filter.

At this time, the purification step, the step of leaving the sterilized fermentation extract in a 4 ℃ refrigerator for more than 3 days to precipitate a solid in the form of particles by the action of gravity; Transferring the supernatant to another vessel by using a siphon phenomenon to separate the clear supernatant from the solid, and removing the solid particles using a 5 μ filter on the residue and filtering the excess herbal extract to combine the separation solution into the vessel; And purifying the fermentation extract by removing dead microorganisms and fine impurities using a micro pore membrane filter.

The composition of the hair regrowth agent and the manufacturing method thereof according to the present invention has the following effects.

First, the present invention promotes hair growth by inhibiting DHT action, a waste product of male hormones.

Secondly, the present invention promotes hair growth by inhibiting hypersensitivity reactions of the scalp.

Third, it inhibits excessive release of lipids of the scalp to improve fat-soluble scalp and promote hair growth.

Fourth, to relax the scalp tissue and improve the amount of blood flow in the capillaries to promote hair root activity to promote hair growth.

1 is a view showing the clinical results according to an embodiment of the present invention.

Looking at a preferred embodiment of the present invention together with the accompanying drawings as follows, when it is determined that the detailed description of the known art or configuration related to the present invention may unnecessarily obscure the subject matter of the present invention The detailed description will be omitted, and the following terms are terms defined in consideration of functions in the present invention and may vary according to the intention or custom of the user or operator, and the definitions refer to the composition of the present invention and the preparation method thereof. It should be made based on the contents throughout the specification to be described.

Hereinafter, the components and features of the composition of the hair regrowth agent according to the preferred embodiment of the present invention will be described.

According to the present invention, the composition of the hair regrowth is composed of six kinds of compositions such as 톳, sukji sulfur, red ginseng, garlic, wolfberry, and black beans as raw materials. In addition, the spray-type scalp-coating hair regrowth formulations use olive liquid, a natural emulsifier, to promote hair root cell metabolism, in order to complete the absorption of the scalp by increasing the affinity of the fat-soluble, water-soluble extract and scalp lipid components in the six types of compositions. Add vitamins such as vitamin C, riboflavin and pyridoxine, and use aloe extract as a scalp moisturizer.

In the present invention, in order to prevent side effects caused by the use of chemicals and hormones of the existing hair regrowth agent, there is an advantage that it is harmless to the scalp because it uses a natural ingredient extracted from the herbal medicine.

On the other hand, brown algae containing fucoidan, fucosterol, fucoxanthine, gamma amino butyric acid are higher in the order of kelp and ,, but the alginate component of the mucopolysaccharide is less than that of kelp in the present invention, because the content of alginic acid is insoluble in kelp. Is used as the main ingredient.

Alginic acid is not toxic for oral administration, but vascular administration causes side effects, and is a macromolecular polysaccharide of high molecular weight, which is not suitable for scalp application and should be removed. Existing methods for removing alginic acid use a method of separating sediment by adding sulfuric acid, but since side effects occur in the scalp, the removal of alginic acid from fermented extract of 톳 uses a method of freezing precipitation below -20 ° C.

In addition, traces of harmful chemical residues are present in the extracts using organic solvent extraction, acid hydrolysis and heat extraction, which may cause irritation and damage to the skin and change and reduction of functional substances. In the present invention, the natural fermentation extraction method is used as a microbial fermentation method that can prevent the loss and change of functional substances.

At this time, the strain used for fermentation uses 'Saccharomyces.spp', and the fermented microorganism extract component is stabilized by fermentation with 5 ~ 10% amount as a nutrient source of the strain and the fermentation microorganism produces low-molecular substances. Conversion to the scalp increases the effective functionality.

In addition, in the fermentation process, the fermenter is sterilized by spraying 70% alcohol to remove unnecessary microorganisms harmful to fermentation. After the disinfection is completed, the heated extract and the extraction foil of each raw material are added together to introduce a complete fermentation extraction process at a temperature of 25 ~ 37 ℃ at room temperature to extract the maximum complete components in a small amount of raw materials.

Meanwhile, the fermentation process uses a secondary fermentation method for at least three months to achieve homogenization of the herbal components by mixing the fermented medicinal products except for 톳 in a large fermenter after the first fermentation for each raw material for three months.

At this time, a high-pressure sterilization method is used for 15 minutes at 121 ℃ 15 pound pressure as a method for removing the alcohol component produced in the fermentation process and killing the microorganisms that have grown in mass. In addition, by removing the microorganisms and the fine particles of the fermented extracts are killed using a negative pressure 'micro pore membrane filter' method.

When the second herbal fermented extract is prepared as described above, olive liquid is used as a natural emulsifier for the formulation of spray-type scalp-coated hair repellent. In other words, the olive liquid added to the formulation is used as a natural emulsifier to homogenize the fat-soluble component and the water-soluble component of the fermented extract, and also emulsifies the lipid component of the fat-soluble scalp to increase the permeability of the active ingredient.

In addition, vitamin C, riboflavin, pyridoxine, and the like are added as hair root cell metabolism promoting water, and aloe extract is used as a scalp moisturizer to prepare a natural fermenting hair growth agent for applying the scalp.

Hereinafter, each component and each manufacturing step of the hair regrowth agent according to the present invention described above will be described in more detail.

<톳 fermented extract preparation>

Brown algae containing 'fucoidan', which has excellent anticoagulant function, have high function in order of kelp and ,, but kelp has a high content of alginic acid, an insoluble and viscous substance of 20,000-240,000. Alginic acid is an unnecessary substance that prevents the penetration of the active ingredient into the scalp. As a method for removing the alginate, it is generally precipitated by sulfuric acid precipitation and purified. This has a disadvantage in that skin irritation occurs due to the use of strongly acidic chemicals.

In the present invention, it is used as a raw material having less alginic acid content than the kelp as a raw material, since there is a small amount of alginic acid in the algae, it is possible to remove alginic acid by low temperature filtration after freezing precipitation.

톳 contains ingredients such as Fucosterol, Fucoidan, Fucoxanthine, Gamma Amino Butyric Acid, minerals (K, Ca, Mg, Na, Fe, Mn, Zn, Cu,), vitamin C, beta-carotene, alpha-tocopherol, polyphenol The action of each component is as follows.

1) Fucosterol: improves blood lipids, improves blood flow, antioxidant activity, inhibits cholesterol and blood pressure rise.

2) Fucoidan: anticoagulant, anticoagulant, antioxidant, immune resilience, anti-tumor, anti-cancer, anti-viral function.

3) Fucoxanthine: A type of carotenoid contained in brown algae, fat burning, antioxidant and anticancer activity.

4) Gamma Amino Butyric Acid: Inhibitory neurotransmitter, cholesterol lowering, triglyceride lowering action.

5) Minerals: Catalytic acid equilibrium, enzyme activation, and protein synthesis in cell metabolism of hair root cells.

6) Vitamin C: Antioxidant, collagen fiber production, dermal papilla cells growth, hair shaft growth promoting action.

In addition, anticoagulant activity, anticoagulant, antioxidant, immune resiliency, anti-tumor, anti-cancer, anti-viral, blood flow improvement, neurotransmitter, cholesterol lowering, triglyceride lowering, hair follicle cells In metabolism, there are physiological activities such as acid group equilibrium, enzyme activation, catalysis of protein synthesis, collagen fiber production, growth of dermal papilla cells, and hair growth promotion.

Hereinafter, 톳 fermented extract manufacturing method will be described in detail.

1) fermentation extraction process

① Washing and grinding: 톳 Wash 40 ~ 60g in water to remove salt, and after 1st water drying, grind to 1-2mm size.

② Sterilization process: After grinding and extracting sterilized powder for 10 minutes in 100 ℃ water, and cooled to room temperature.

③ Fermentation process: The fermenter is sprayed with 70% alcohol and disinfected. 1kg of water and sterilized sesame extract are added together, fermented with 5-10% of the fermenter, and then inoculated with Saccharomyces.spp strain.

④ Fermentation temperature and duration: Extract fermentation for more than 6 months at 35 ℃.

⑤ sterilization and alcohol removal process; After the supernatant of the fermentation extract is separated, the solution is autoclaved at 121 ° C. 15 pounds pressure for 15 minutes to kill microorganisms, and volatilizes the alcohol component produced during the fermentation.

2) Alginic Acid Separation Process

① Sterilize 톳 extracts in freezer at -20 ℃ or lower for 3 days or more to ensure complete precipitation.

② thaw frozen extract 톳 at 4 ℃.

③ To separate alginic acid precipitated from the thawed extract and clear supernatant, transfer the supernatant to another vessel using siphon phenomenon, remove the alginic acid using a 25μ filter, and filter out the remaining extract. .

3) Purification Process

In order to increase the efficiency of the 'micro pore membrane filter', it is first separated by filtration with a 5μ filter and a second filtration process is introduced as a final purification process.

① 1st refining process: 알 Fermented extract separated from alginic acid is left in 4 ℃ refrigerator for more than 3 days to precipitate solids in the form of particles by the action of gravity. In order to separate the clear supernatant from the solid, the supernatant is transferred to another vessel using a siphon phenomenon, and the residue is combined with the vessel by removing the solid particles using a 5 μ filter and filtering the extra herbal extract.

② Secondary purification process: Purify fermented extract by removing dead microorganisms and fine impurities using 'micro pore membrane filter'.

As described above, 톳 fermented extract manufacturing method has been described, and then, the fermented extract manufacturing method for herbal ingredients such as sukji sulfur, red ginseng, garlic, wolfberry, black beans and the like.

<Preparation of primary herbal fermented extract>

1. Manufacture of Sookjihwang Fermented Extract

Sukjiwang contains catapol, rehmannin, aucubin, rehmannioside (A, B, C, D), leonuride, monomeltittoside, dihydrocatalpol, amino acid, and other trace elements.

In agreement, Sooji Hwang is said to be warm and have a sweet and bitter taste. Sukjiwang replenishes the blood and blackens the hair, fills the bone marrow and makes the muscles healthy. He also said that it strengthens bones, replenishes weaknesses, makes blood flow through, improves energy, and keeps ears and eyes healthy. In addition, it is recorded that the raw material of the hair is blood, and if the blood circulation to the scalp is smooth, the hair is glossy and thick, but if blood circulation is not possible, the hair becomes rough and thin and hair loss appears.

Lack of blood results in thinning hair, hair loss, and paleness and dizziness due to lack of color on the face. The eyes become tired and the hands and feet go away, and the nails become pale. The growth-promoting effect of Sukjiwang used for the treatment of cardiovascular and neurological diseases through the treatment of damaged spinal cord axon was verified.

In addition, succinate sulfur has physiological activities such as lowering total cholesterol and triglyceride, antioxidative effects such as increasing glutathione peroxidase activity, decreasing serum peroxide lipid content, and increasing super oxide dismutase activity.

-Sukjihwang 1st fermentation extract manufacturing process

① Washing: Wash 30 ~ 60g of Sukji sulfur with water to remove impurities.

② Sterilization process: After heating and extracting sterilized sulfuric acid in 100 ℃ water for 10 minutes, it is cooled to room temperature.

③ Fermentation process: The fermenter is sprayed with 70% alcohol and disinfected. 1 kg of water, sterilized sujihwang and extract are added together, fermented with 5-10% of the fermenter, and then inoculated with Saccharomyces.spp strain.

④ 1st fermentation temperature and period: Extract fermentation 3 months at 35 ℃.

2. Preparation of the First Fermented Extract of Ginseng

Ginseng is an alkaloid compound that contains matrine, matrin N-oxide, allomatrine, isomatrine, sophoranol, sophoranol N-oxide, sophoramine, N-methylcytisine, anagyrine, batifoline, and phytoestrogen. It is composed of such isoflvones compounds.

In addition, ginseng inhibits the activity of histamine, cytokine, and β-hexosaminidase in allergic hypersensitivity, and is effective in preventing hair loss, dermatitis such as eczema, skin itching, and antibacterial activity.

-Ginseng Fermented Extract Manufacturing Process

① Washing: Wash 30 ~ 60g of red ginseng in water to remove impurities.

② Sterilization process: The washed ginseng is extracted and sterilized by heating for 10 minutes in 100 ℃ water and cooled to room temperature.

③ Fermentation process: The fermenter is sprayed with 70% alcohol and disinfected. 1 kg of water and sterilized gourdaceae extract are added to the fermenter together. After fermentation with 5 ~ 10%, inoculate Saccharomyces.spp strain.

④ 1st fermentation temperature and period: Extract fermentation 3 months at 35 ℃.

3. Garlic primary fermentation extract manufacturing

Garlic contains alliin, allicin, ajoene, scordinin, fructooligosaccharide, allithiamine and essential oils such as citral, geraniol, linanol and α-β-phellandrene, as well as garlic vitamin B1 (altyamine).

Garlic is an antibacterial, insecticidal, triglyceride and cholesterol lowering agent, thrombolytic action to improve capillary blood circulation, lipid peroxidation inhibitory effect on vascular endothelial cell protection, antioxidant activity, anti-cancer effect. It acts to reduce lipids in the blood. This is because of arteriosclerosis. Spotlighted as a preventive and therapeutic agent for hypertension In addition, by expanding the peripheral blood vessels of the skin has a physiological activity that facilitates blood circulation.

-Garlic Fermented Extract Manufacturing Process

① Washing: Wash 50 ~ 100g of garlic with water to remove impurities and grind to 1-2mm size.

② Sterilization process: The washed garlic is extracted and sterilized by heating for 10 minutes in 100 ℃ water and cooled to room temperature.

③ Fermentation process: The fermenter is sprayed with 70% alcohol and sterilized. 1 kg of water, sterilized garlic and extracts are added together, and fermented with 5-10% of the fermenter, and then inoculated with Saccharomyces.spp strain.

④ 1st fermentation temperature and period: Extract fermentation 3 months at 35 ℃.

4. Preparation of Gojija Primary Fermentation Extract

Wolfberry contains betaine, rutin, diosgenin, physalien, zeaxanthin, uracil, β-sitosterol, palmitic acid, linolenic acid, cornin, morrnoniside, loganin, tanin, saponin, ascorbic acid, mineral, amino acid.

Gojija has a physiological activity such as anti-hair loss and hair growth effect, anti-aging, detoxification, cell replication function, capillary reinforcement, antioxidant activity, cholesterol reduction in blood, collagen synthesis by reducing DHT content by enhancing cellular immunity. .

In oriental medicine, it is used as a tonic or antipyretic and has excellent liver function protection, so there are few side effects. In addition, it improves vision and prevents adult diseases such as diabetes, improves the function of lungs and kidneys, and mixes with perilla oil to mature and then applied to the hair to prevent the occurrence of gray hair.

In addition, gojija hematopoietic action, cholesterol lowering action, anti-fatty liver action, blood pressure drop, hypoglycemia, growth growth, anti-cancer and other components such as betaine, beaxanthin, carotene, thiamine, vitamin A, B1, B2, C, etc. It contains. The effects of goji berries goji are used for backache as chronic hepatitis, cirrhosis, tonic, antipyretic. Gugijaroot skin is called Jigolpi (地骨皮) is used as an antipyretic such as beef, chills, etc. in Chinese medicine. In the Xinong main menarche, written about 1800 years ago in the Hanhan period, it contains herbs, or ginseng, which are poisonous. 『Bonchogyeong』 has been introduced that it takes a long time to harden the musculature, lighten the body, so that it does not grow old and does not burn hot and cold. In civilian use, we use it as a goji or goji

-Gojija Fermented Extract Manufacturing Process

① Washing: Wash 30 ~ 60g of wolfberry in water to remove impurities.

② Sterilization Process: After washing and sterilizing the heated wolfberry in 100 ℃ water for 10 minutes, cool it to room temperature.

③ Fermentation process: The fermenter is sprayed with 70% alcohol and disinfected. 1 kg of water, sterilized goji and extract are added together, and fermented with 5-10% of the fermenter. Inoculate Saccharomyces.spp strain.

④ 1st fermentation temperature and period: Extract fermentation 3 months at 35 ℃.

5. Preparation of Black Bean Primary Fermentation Extract

Black soybean contains ingredients such as isoflavine, stachyrose, raffinose, sucrose, saponin, phytic acid, essential amino acid, unsaturated fatty acid linoleic acid, oleic acid, palmitic acid, vitamin E and protein.

In addition, black beans have physiological activities such as antioxidant effect, vegetable estrogen effect, cholesterol lowering, chronic disease prevention, strengthening immune function, lowering lipid oxidation reaction, promoting blood circulation.

Herbal wood is written about the efficacy of black soybeans, "controls the kidneys, eliminates edema, activates blood circulation and releases the poison of all drugs." In addition, cysteine, an essential ingredient for hair growth, is also effective in preventing hair loss.

-Black bean fermented extract manufacturing process

① Washing and grinding: Wash 50 ~ 80g of black beans in water to remove impurities, dry moisture, and grind to 1 ~ 2mm.

② sterilization process: The black soybeans are extracted and sterilized by heating for 10 minutes in 100 ℃ water and cooled to room temperature.

③ Fermentation process: The fermenter is sprayed with 70% alcohol and disinfected. 1 kg of water and sterilized black soybeans and extracts are added together, and fermented with 5-10% of the fermenter, and then inoculated with Saccharomyces.spp strain. .

④ 1st fermentation temperature and period: Extract fermentation 3 months at 35 ℃.

In the above, the method for preparing primary herbal fermented extracts for herbal ingredients such as sukji sulfur, red ginseng, garlic, wolfberry, and black beans has been described. Next, the secondary fermentation manufacturing method for the first fermented herbal extract.

<Second Herbal Fermented Extract Preparation>

In order to achieve the component homogenization of the first fermented herbal extract as described above, the secondary fermentation process is further processed.

1. Second fermentation process

① Fermenter is sprayed with 70% alcohol and sterilized, and 5 kinds of primary fermentation products such as Sukjihwang fermentation extract, red ginseng fermentation extract, garlic fermentation extract, wolfberry fermentation extract and black soybean fermentation extract are mixed and mixed in a large fermenter.

② Second fermentation temperature and period: Extract fermentation for more than 3 months at 30 ℃.

2. Sterilization and Alcohol Removal Process

① Sterilization process and alcohol component removal process: After separating the supernatant of the fermentation extract, the solution is autoclaved at 121 ℃ 15 pounds pressure for 15 minutes to kill the microorganisms, alcohol components produced in the fermentation process and present in the fermentation broth Volatilize.

3. Purification Process

In order to increase the efficiency of the 'micro pore membrane filter', the filter is first separated by a 5μ filter and a second filtration process is introduced as a final purification process.

① First purification process: Sterilized fermented extract is left in the 4 ℃ freezer for more than 3 days to precipitate solids in the form of particles. In order to separate the clear supernatant from the solid, the supernatant is transferred to another vessel using a siphon phenomenon, and the residue is combined with the vessel by removing the solid particles using a 5 μ filter and filtering the extra herbal extract.

② Secondary purification process: Purify fermented extract by removing dead microorganisms and fine impurities using 'micro pore membrane filter'.

In the above, the method for producing a fermenting hair regrowth using the five components and the herbal medicine according to the present invention has been described. The content for the spray-type scalp-coated hair-repellent formulation using the prepared fermentation hair-repellent composition is as shown in Table 1, the content of these components can be changed according to the needs of the manufacturer.

Compositions Comprising Hair Regrowth Content (% by weight) Purified water 67 발효 and five herbal fermented extracts 30 Olive Liquid One Aloe extract One vitamin 0.5 Neutralization products 0.5 Spices a very small amount system 100

Clinical Example

Ten subjects were given a natural hair regrowth prepared by the microbial fermentation process according to the present invention, and then sprayed to the hair loss site once every morning and night, and then massaged lightly.

In order to increase the satisfaction of the subjects, self-assessment was conducted. For the self-evaluation, the hair loss site was selected based on the center point of the forehead, and the number of hairs generated in the area of 1 cm 2 was examined to examine the increase and decrease of the hair.

As a raw material, six kinds of herbal compositions such as 톳, succinate, red ginseng, garlic, wolfberry and black soybean were used as raw materials. To spray for 10 weeks to the scalp, the analysis of the results are shown in Table 2 below.

subject age gender Symptom Hair Loss Progress Period apply
term Numerical result by 1cm2 site Week 0 After 4 weeks 6 weeks later 8 weeks later 10 weeks later One 58 south Androgenetic alopecia 27 years 10 weeks 26 29 32 32 34 2 53 south Androgenetic alopecia 19 years 10 weeks 44 46 49 50 50 3 42 south Androgenetic alopecia 12 years 10 weeks 64 71 73 72 75 4 52 south Androgenetic alopecia 16 years 10 weeks 33 36 38 39 40 5 44 south Androgenetic alopecia 8 years 10 weeks 52 57 59 61 62 6 62 south Androgenetic alopecia 25 years 10 weeks 20 23 26 27 27 7 33 south Androgenetic alopecia 2 years 10 weeks 51 56 59 60 62 8 59 south Androgenetic alopecia 11 years 10 weeks 22 23 26 28 29 9 53 south Androgenetic alopecia 7 years 10 weeks 19 24 27 28 28 10 49 south Androgenetic alopecia 5 years 10 weeks 48 50 51 52 52

Figure 1 is a pre-clinical and post-clinical photograph of the seventh subject (age 33, male) out of 10 subjects, it was proved that a significant effect on the hair growth by using the hair regrowth agent according to the present invention.

As described above, various substitutions, modifications, and changes can be made by those skilled in the art without departing from the technical spirit of the present invention, and thus, the embodiments and the accompanying drawings are limited. It doesn't happen.

Claims (9)

In the composition of the hair regrowth agent,
톳 fermented extract extracted by fermentation at 35 ° C. for 6 months after sterilizing the pulverized powder;
Sukji sulfur fermented extract extracted by fermentation for three months after the sterilization of succinct;
After sterilizing the ginseng, fermented extract extracted by fermentation for 3 months at 35 ℃;
After the sterilization of garlic, garlic fermented extract extracted by fermentation for 3 months at 35 ℃;
After sterilization of the wolfberry, fermented extract extracting fermented for 3 months at 35 ℃; And
After sterilizing the black beans, fermented black bean extract extracted by fermentation for 3 months at 35 ℃; includes,
The fermented extract of Sukji sulfur, fermented ginseng extract, garlic fermented extract, goji berry fermented extract and black soybean fermented extract is a natural fermentation hair regrowth composition, characterized in that the secondary fermentation for at least 3 months at 30 ℃.
According to claim 1, wherein the fermented extract is fermented,
Natural fermentation hair regrowth composition, characterized in that the alginate is separated by freeze precipitation at -20 ℃ or less.
The method of claim 1, wherein the fermentation extract of each fermentation method,
A natural fermentation hair repellent composition, characterized in that the sterilized raw materials with water are added to a fermenter and added to 5 to 10% by weight, followed by inoculation of Saccharomyces.spp strains.
2. The composition of claim 1,
Natural liquid emulsifier olive liquid, hair follicle cell metabolism promoter, vitamin, scalp moisturizer, characterized in that it further comprises aloe extract as a moisturizer.
In the manufacturing method of the hair regrowth agent,
살균 fermented extract manufacturing step of sterilizing the pulverized 톳 powder, followed by extracting by fermentation for at least 6 months at 35 ℃;
After the sterilization treatment of Sookjihwang, gosam, garlic, wolfberry and black soybeans, the first herbal fermented extract manufacturing step of extracting by fermentation for 3 months at 35 ℃; And
It comprises a secondary fermentation extract manufacturing step of fermenting the first fermented Sookji sulfur fermentation extract, ginseng fermentation extract, garlic fermentation extract, goji berry fermentation extract and black soybean fermentation extract secondary fermentation for at least 3 months at 30 ℃; A method for producing a natural fermenting hair repellent composition characterized by the above.
The method of claim 5, wherein the fermented extract preparation step
The freeze precipitation of the fermented 톳 extract at -20 ° C or less to separate alginic acid; The method of producing a natural fermentation hair regrowth composition characterized in that it further comprises.
According to claim 5, The primary herbal fermentation extract manufacturing step,
Washing each raw material to remove impurities;
Sterilizing the washed raw materials and then cooling them at room temperature; And
Injecting the sterilized raw material into the fermenter together with water, and added to 5 to 10% by weight, inoculating the Saccharomyces.spp strain and fermentation; natural fermentation hair regrowth composition comprising a.
According to claim 5, The secondary herbal fermentation extract manufacturing step,
Adding each of the primary fermentation extracts to a fermenter and mixing them;
Removing the microorganism from the fermented extract of the second fermentation and removing the alcohol component; And
Purifying the fermented extract by filtration with a filter; Method of producing a natural fermentation hair regrowth composition characterized in that it further comprises.
The method of claim 8, wherein the purification step,
Leaving the sterilized fermentation extract in a 4 ° C. refrigerator for at least 3 days to precipitate solids in the form of particles by the action of gravity;
Transferring the supernatant to another vessel by using a siphon phenomenon to separate the clear supernatant from the solid, and removing the solid particles using a 5 μ filter on the residue and filtering the excess herbal extract to combine the separation solution into the vessel; And
Purifying the fermentation extract by removing the dead microorganisms and fine impurities using a micro pore membrane filter; Method of producing a natural fermentation hair regrowth composition comprising a.

Images