KR20010005746A - 화학적, 열적으로 안정적인 노라스테미졸 조성물 - Google Patents

화학적, 열적으로 안정적인 노라스테미졸 조성물 Download PDF

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Publication number: KR20010005746A
Authority: KR; South Korea
Prior art keywords: lactose; pharmaceutically acceptable; pharmaceutical composition; nolastemizol; composition
Prior art date: 1997-03-26
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

KR1019997008817A

Other languages

English (en)

Korean (ko)

Inventor

마틴피. 레드몬

할티. 버틀러

스테판에이. 왈드

Original Assignee

더글라스이.리디치

세프라코 아이엔시.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-03-26

Filing date

1998-03-25

Publication date

2001-01-15

1998-03-25 Application filed by 더글라스이.리디치, 세프라코 아이엔시. filed Critical 더글라스이.리디치

2001-01-15 Publication of KR20010005746A publication Critical patent/KR20010005746A/ko

Status Ceased legal-status Critical Current

Links

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229920000523 polyvinylpolypyrrolidone Polymers 0.000 description 1
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239000011591 potassium Substances 0.000 description 1
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239000004302 potassium sorbate Substances 0.000 description 1
235000010241 potassium sorbate Nutrition 0.000 description 1
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229920001592 potato starch Polymers 0.000 description 1
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CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
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VILMUCRZVVVJCA-UHFFFAOYSA-M sodium glycolate Chemical compound [Na+].OCC([O-])=O VILMUCRZVVVJCA-UHFFFAOYSA-M 0.000 description 1
235000019333 sodium laurylsulphate Nutrition 0.000 description 1
JXKPEJDQGNYQSM-UHFFFAOYSA-M sodium propionate Chemical compound [Na+].CCC([O-])=O JXKPEJDQGNYQSM-UHFFFAOYSA-M 0.000 description 1
235000010334 sodium propionate Nutrition 0.000 description 1
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ISXSCDLOGDJUNJ-UHFFFAOYSA-N tert-butyl prop-2-enoate Chemical compound CC(C)(C)OC(=O)C=C ISXSCDLOGDJUNJ-UHFFFAOYSA-N 0.000 description 1
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AOBORMOPSGHCAX-DGHZZKTQSA-N tocofersolan Chemical compound OCCOC(=O)CCC(=O)OC1=C(C)C(C)=C2O[C@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C AOBORMOPSGHCAX-DGHZZKTQSA-N 0.000 description 1
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MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 description 1
FGQOOHJZONJGDT-UHFFFAOYSA-N vanillin Natural products COC1=CC(O)=CC(C=O)=C1 FGQOOHJZONJGDT-UHFFFAOYSA-N 0.000 description 1
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239000001993 wax Substances 0.000 description 1
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XOOUIPVCVHRTMJ-UHFFFAOYSA-L zinc stearate Chemical compound [Zn+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O XOOUIPVCVHRTMJ-UHFFFAOYSA-L 0.000 description 1
UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
239000002076 α-tocopherol Substances 0.000 description 1
235000004835 α-tocopherol Nutrition 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

KR1019997008817A 1997-03-26 1998-03-25 화학적, 열적으로 안정적인 노라스테미졸 조성물 Ceased KR20010005746A (ko)

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US82447797A	1997-03-26	1997-03-26
US8/824,477		1997-03-26
US85178697A	1997-05-06	1997-05-06
US8/851,786		1997-05-06
PCT/US1998/005701 WO1998042379A2 (en)	1997-03-26	1998-03-25	Chemically and thermally stable norastemizole formulations

Publications (1)

Publication Number	Publication Date
KR20010005746A true KR20010005746A (ko)	2001-01-15

Family

ID=27124816

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
KR1019997008817A Ceased KR20010005746A (ko)	1997-03-26	1998-03-25	화학적, 열적으로 안정적인 노라스테미졸 조성물

Country Status (13)

Country	Link
EP (1)	EP1035869A1 (ru)
JP (1)	JP2002512614A (ru)
KR (1)	KR20010005746A (ru)
CN (1)	CN1257431A (ru)
AR (1)	AR012187A1 (ru)
BR (1)	BR9808428A (ru)
CA (1)	CA2284705A1 (ru)
HU (1)	HUP0001823A3 (ru)
NO (1)	NO994655L (ru)
NZ (3)	NZ527200A (ru)
RU (1)	RU2214245C2 (ru)
WO (1)	WO1998042379A2 (ru)
ZA (1)	ZA982562B (ru)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CZ289261B6 (cs) *	2000-07-11	2001-12-12	Léčiva, A.S.	Tableta vyrobitelná přímým tabletováním, obsahující aktivní látku kyselinu 4-amino-1-hydroxybutyliden-1,1-bisfosfonovou, a způsob její výroby
EP2201982A1 (en) *	2008-12-24	2010-06-30	INSERM (Institut National de la Santé et de la Recherche Médicale)	Histamine H4 receptor antagonists for the treatment of vestibular disorders
ES2736155T3 (es) *	2009-08-24	2019-12-26	Abdi Ibrahim Ilac Sanayi Ve Ticaret Anonim Sirketi	Comprimidos de otilonio por compresión directa

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3781173T2 (de) *	1986-02-03	1992-12-17	Janssen Pharmaceutica Nv	N-heterozyklische-4-piperidinamine enthaltende anti-histaminische zusammensetzungen.
DE4037426A1 (de) *	1990-11-24	1992-05-27	Kali Chemie Pharma Gmbh	Piperidinoalkylbenzoxazin- und -thiazin-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
CA2143610C (en) *	1992-09-03	2004-08-24	Raymond L. Woosley	Use of norastemizole for the treatment of allergic disorders
AU703701B2 (en) *	1995-11-17	1999-04-01	Aventis Pharmaceuticals Inc.	Substituted 4-(1H-benzimidazol-2-YL-amino)piperidines useful for the treatment of allergic diseases
AR008293A1 (es) *	1996-08-16	1999-12-29	Schering Corp	Composicion que comprende una cantidad antihistaminica para el tratamiento de las respuestas alergicas de las vias respiratorias superiores

1998
- 1998-03-25 EP EP98914283A patent/EP1035869A1/en not_active Withdrawn
- 1998-03-25 CA CA002284705A patent/CA2284705A1/en not_active Abandoned
- 1998-03-25 KR KR1019997008817A patent/KR20010005746A/ko not_active Ceased
- 1998-03-25 WO PCT/US1998/005701 patent/WO1998042379A2/en not_active Application Discontinuation
- 1998-03-25 NZ NZ52720098A patent/NZ527200A/xx unknown
- 1998-03-25 RU RU99122607/14A patent/RU2214245C2/ru not_active IP Right Cessation
- 1998-03-25 CN CN98805457A patent/CN1257431A/zh active Pending
- 1998-03-25 BR BR9808428-3A patent/BR9808428A/pt not_active IP Right Cessation
- 1998-03-25 JP JP54589398A patent/JP2002512614A/ja active Pending
- 1998-03-25 HU HU0001823A patent/HUP0001823A3/hu unknown
- 1998-03-25 NZ NZ527201A patent/NZ527201A/xx unknown
- 1998-03-25 NZ NZ517472A patent/NZ517472A/en unknown
- 1998-03-26 ZA ZA982562A patent/ZA982562B/xx unknown
- 1998-03-26 AR ARP980101398A patent/AR012187A1/es unknown
1999
- 1999-09-24 NO NO994655A patent/NO994655L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
NO994655D0 (no)	1999-09-24
EP1035869A1 (en)	2000-09-20
NZ527200A (en)	2004-12-24
RU2214245C2 (ru)	2003-10-20
HUP0001823A2 (hu)	2001-04-28
AU735257B2 (en)	2001-07-05
ZA982562B (en)	1998-10-01
NZ527201A (en)	2004-12-24
WO1998042379A3 (en)	2001-03-01
NO994655L (no)	1999-11-15
CN1257431A (zh)	2000-06-21
AU6868098A (en)	1998-10-20
HUP0001823A3 (en)	2002-04-29
AR012187A1 (es)	2000-09-27
JP2002512614A (ja)	2002-04-23
BR9808428A (pt)	2000-05-23
WO1998042379A2 (en)	1998-10-01
NZ517472A (en)	2003-08-29
CA2284705A1 (en)	1998-10-01

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Date	Code	Title	Description
1999-09-27	PA0105	International application	Patent event date: 19990927 Patent event code: PA01051R01D Comment text: International Patent Application
2001-01-15	PG1501	Laying open of application
2003-01-21	A201	Request for examination
2003-01-21	PA0201	Request for examination	Patent event code: PA02012R01D Patent event date: 20030121 Comment text: Request for Examination of Application
2004-11-30	E902	Notification of reason for refusal
2004-11-30	PE0902	Notice of grounds for rejection	Comment text: Notification of reason for refusal Patent event date: 20041130 Patent event code: PE09021S01D
2005-07-28	E601	Decision to refuse application
2005-07-28	PE0601	Decision on rejection of patent	Patent event date: 20050728 Comment text: Decision to Refuse Application Patent event code: PE06012S01D Patent event date: 20041130 Comment text: Notification of reason for refusal Patent event code: PE06011S01I