KR102695533B1 - Vacuum collection tube manufacturing device and vacuum collection tube manufacturing method using the same - Google Patents

Abstract

The present invention relates to a vacuum blood collection tube manufacturing device and a vacuum blood collection tube manufacturing method using the same.
More specifically, the present invention relates to a vacuum blood collection tube manufacturing device for manufacturing a vacuum blood collection tube, comprising: a chamber portion having one or more tubes accommodated therein; a vacuum pump for discharging air inside the chamber portion to the outside of the chamber portion so that the inside of the chamber portion becomes a vacuum state; a connecting portion comprising a chamber pump pipe configured to connect the chamber portion and the vacuum pump; and an injection portion configured to inject a reagent into one or more tubes accommodated in the chamber portion. According to the present invention, the present invention has the effect of preventing the generation of air bubbles in the process of injecting the reagent into the tube by allowing the injection portion to inject the reagent into the tube while the inside air of the chamber portion becomes a vacuum state by discharging the inside air of the chamber portion to the outside of the chamber portion by the vacuum pump.

Description

{VACUUM COLLECTION TUBE MANUFACTURING DEVICE AND VACUUM COLLECTION TUBE MANUFACTURING METHOD USING THE SAME}

The present invention relates to a vacuum blood collection tube manufacturing device and a vacuum blood collection tube manufacturing method using the same.

More specifically, the present invention relates to a vacuum blood collection tube manufacturing device configured to prevent the generation of air bubbles in the process of injecting a reagent into a tube by allowing reagent to be injected into a tube by an injection unit while the inside of the chamber is in a vacuum state by exhausting the inside air of the chamber to the outside of the chamber by a vacuum pump, and a vacuum blood collection tube manufacturing method using the same.

As interest in health increases and health screening technology rapidly advances, a wide range of blood tests, including serum biochemical tests, serum immunoassays, and blood cell tests, are contributing greatly to the prevention and early diagnosis of diseases.

These blood tests, regardless of the subject or type of test, involve collecting a certain amount of blood and placing it in a specific container during the storage, transport, and processing process.

The most common container used at this time is a blood collection tube, and some of these blood collection tubes are provided as vacuum blood collection tubes by forming a vacuum inside, thereby allowing blood to be easily drawn into the container during the blood collection process.

These blood collection tubes come in several types depending on their intended use and size, but are generally composed of a tube with an open top and a cap that is inserted or placed over the opening of the tube to seal the inside of the tube. The inside of the tube is filled with a liquid filler such as a gel or reagent that prevents or promotes blood clotting.

At this time, in the process of filling the inside of the vacuum blood collection tube with liquid fillers such as gels and reagents, if the filling process is carried out without separate equipment, there is a problem that air bubbles are generated in the liquid fillers such as gels and reagents filled inside the vacuum blood collection tube, causing issues such as weak vacuum or insufficient amount of fillers during distribution. Therefore, general vacuum blood collection tube manufacturers fill the inside of the vacuum blood collection tube with liquid fillers such as gels and reagents, and then heat the vacuum blood collection tube using a deaerator to remove air bubbles inside the vacuum blood collection tube before delivery.

However, this method of removing air bubbles inside a vacuum blood collection tube using a degassing device is very inefficient in terms of cost and time because it requires an additional process, and this reduces the productivity of the product, which can even lower the reliability of the product, which is very important especially for medical equipment.

As a technology related to this, Korean Patent No. 10-1617623 discloses a manufacturing facility and a manufacturing method for a vacuum blood collection tube equipped with a crack inspection device and a reagent injection device.

The above-described conventional vacuum blood collection tube manufacturing facility and manufacturing method equipped with a crack inspection device and a reagent injection device relate to a vacuum blood collection tube manufacturing facility and manufacturing method, and more specifically, to a vacuum blood collection tube manufacturing facility and manufacturing method equipped with a crack inspection device and a reagent injection device capable of inspecting the presence of cracks in the tube of a vacuum blood collection tube that separates components while storing collected blood, thereby eliminating the defect rate of the vacuum blood collection tube, ensuring that a reagent that promotes separation of blood components is applied evenly, and maintaining the vacuum level inside each vacuum blood collection tube evenly.

However, the above-mentioned conventional technology is configured to preheat a tube coated with a reagent by providing a separate preheating device and then combine the cap in a vacuum state, or to combine the cap in a state including bubbles and then preheat in a separate preheating space for a certain period of time to remove the bubbles. In this case, as described above, there is a problem that not only is it inefficient in terms of cost and time required to use the preheating device and location, but even the reliability of the product may decrease.

Korean Patent Publication No. 10-1617623 (April 27, 2016) Korean Patent Publication No. 10-2169712 (November 20, 2020)

The present invention has been made to solve the above problems, and the problem to be solved by the present invention is to provide a vacuum blood collection tube manufacturing device configured to prevent the generation of air bubbles during the process of injecting a reagent into a tube by injecting a reagent into the tube through an injection unit while the inside of the chamber is in a vacuum state by exhausting the inside of the chamber to the outside of the chamber by a vacuum pump, and a vacuum blood collection tube manufacturing method using the same.

In order to solve the above-mentioned problem, according to one embodiment of the present invention, a vacuum blood collection tube manufacturing device for manufacturing a vacuum blood collection tube is characterized by including: a chamber portion having one or more tubes accommodated therein; a vacuum pump for exhausting air inside the chamber portion to the outside of the chamber portion so that the inside of the chamber portion becomes a vacuum state; a connecting portion including a chamber pump pipe configured to connect the chamber portion and the vacuum pump; and an injection portion configured to inject a reagent into one or more tubes accommodated in the chamber portion.

Meanwhile, in order to solve the above-mentioned problem, according to another embodiment of the present invention, a vacuum blood collection tube manufacturing device for manufacturing a vacuum blood collection tube is characterized by including: a chamber part having one or more tubes accommodated therein; a tank part provided at a position connected to the chamber part; a vacuum pump for discharging air inside the tank part to the outside of the tank part so that the inside of the tank part is in a vacuum state; a connection part including a chamber tank pipe configured to connect the chamber part and the tank part, a tank pump pipe configured to connect the tank part and the vacuum pump, and a valve member installed in the chamber tank pipe to open and close the chamber tank pipe; and an injection part configured to inject a reagent into one or more tubes accommodated in the chamber part.

In addition, the present invention is characterized by further including a transport section for transporting a tray containing one or more tubes; and an elevating section for elevating the chamber section to open and close the interior of the chamber section.

In addition, it is characterized in that it further includes a control unit configured to control the operation of the vacuum pump, valve member, and injection unit.

In addition, the control unit is characterized in that it controls the vacuum pump when first driven so that the inside of the tank part changes into a vacuum state, and when one or more tubes are accommodated inside the chamber part, it controls the valve member to open the chamber tank pipe so that the inside of the chamber part changes into a vacuum state.

In addition, the control unit includes a first detection sensor configured to detect and transmit an internal pressure of the chamber portion; and a second detection sensor configured to detect and transmit an internal pressure of the tank portion, and the control unit is characterized in that it is configured to determine the vacuum state of each of the chamber portion and the tank portion through the internal pressure of the chamber portion transmitted from the first detection sensor and the internal pressure of the tank portion transmitted from the second detection sensor.

Meanwhile, a vacuum blood collection tube manufacturing method according to an embodiment of the present invention for solving the above-mentioned problem is characterized by including a first receiving step in which one or more tubes are received inside a chamber part, a first pump driving step in which a vacuum pump is driven to discharge air inside the chamber part to the outside of the chamber part, thereby lowering the internal pressure of the chamber part and changing into a vacuum state, and a first reagent injection step in which a reagent is injected into one or more tubes received in the chamber part after the inside of the chamber part is changed into a vacuum state.

Meanwhile, a vacuum blood collection tube manufacturing method according to another embodiment of the present invention for solving the above-mentioned problem is characterized by including a second pump driving step for driving a vacuum pump to discharge air inside the tank to the outside of the tank to thereby lower the internal pressure of the tank and change it into a vacuum state; a second receiving step for accommodating one or more tubes inside the chamber; a valve opening step for controlling a valve member configured to open and close the chamber tank tube to an open state so that the internal pressure of the tank part changed into the vacuum state and the internal pressure of the chamber part are fused to thereby change the internal pressure of the chamber part into a vacuum state; and a second reagent injection step for injecting a reagent into one or more tubes accommodated in the chamber part after the inside of the chamber part is changed into a vacuum state.

In addition, the invention is characterized in that it further includes a third pump driving step of controlling the valve member to a sealed state and driving the vacuum pump to lower the internal pressure of the tank part by discharging the air inside the tank part to the outside of the tank part after the inside of the chamber part has been changed to a vacuum state.

In addition, it is characterized in that the internal pressure of the tank in the second pump driving stage and the third pump driving stage is at least lower than the internal pressure of the tank in the valve opening stage.

According to the vacuum blood collection tube manufacturing device and the vacuum blood collection tube manufacturing method using the same according to the present invention, the air inside the chamber is discharged to the outside of the chamber by a vacuum pump, and the inside of the chamber is in a vacuum state, and then the reagent is injected into the tube by the injection unit, thereby preventing the generation of air bubbles during the process of injecting the reagent into the tube.

In addition, according to the present invention, when the inside of the tank provided between the chamber and the vacuum pump is made into a vacuum state by the vacuum pump, and then one or more tubes are accommodated inside the chamber, and the valve member is controlled to an open state, the inside of the chamber is quickly made into a vacuum state, thereby saving the time for making the inside of the chamber into a vacuum state.

Figure 1 is a drawing showing a vacuum blood collection tube manufacturing device according to one embodiment of the present invention.
FIGS. 2A to 2C are side views of a vacuum blood collection tube manufacturing device according to one embodiment of the present invention.
FIG. 3 is a drawing showing a vacuum blood collection tube manufacturing device according to another embodiment of the present invention.
FIG. 4 is a block diagram showing a method for manufacturing a vacuum blood collection tube using a vacuum blood collection tube manufacturing device according to one embodiment of the present invention.
FIG. 5 is a block diagram showing a method for manufacturing a vacuum blood collection tube using a vacuum blood collection tube manufacturing device according to another embodiment of the present invention.
FIG. 6 is a block diagram showing a state in which a third pump driving step is added to a method for manufacturing a vacuum blood collection tube using a vacuum blood collection tube manufacturing device according to another embodiment of the present invention.

The present invention can have various modifications and various embodiments, and specific embodiments are illustrated in the drawings and described in detail. However, this is not intended to limit the present invention to specific embodiments, but should be understood to include all modifications, equivalents, or substitutes included in the spirit and technical scope of the present invention.

When it is said that a component is "connected" or "connected" to another component, it should be understood that it may be directly connected or connected to that other component, but there may also be other components present in between.

On the other hand, when it is said that a component is "directly connected" or "directly connected" to another component, it should be understood that there are no other components in between.

The terminology used herein is only used to describe particular embodiments and is not intended to limit the present invention. The singular expression includes the plural expression unless the context clearly indicates otherwise. In this application, it should be understood that the terms "comprises" or "has" and the like are intended to specify the presence of a feature, number, process, operation, component, part or combination thereof described in the specification, but do not exclude in advance the possibility of the presence or addition of one or more other features, numbers, processes, operations, components, parts or combinations thereof.

Unless otherwise defined, all terms used herein, including technical or scientific terms, have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. Terms defined in commonly used dictionaries, such as those defined in common dictionaries, should be interpreted as having a meaning consistent with the meaning they have in the context of the relevant art, and shall not be interpreted in an idealized or overly formal sense, unless expressly defined in this application.

Hereinafter, the present invention will be described in more detail with reference to the attached drawings. Prior to this, the terms or words used in this specification and claims should not be interpreted as limited to their conventional or dictionary meanings, and should be interpreted as meanings and concepts that conform to the technical idea of the present invention based on the principle that the inventor can appropriately define the concept of the term in order to explain his or her own invention in the best way. In addition, if there is no other definition for the technical and scientific terms used, they have the meanings commonly understood by those with ordinary knowledge in the technical field to which this invention belongs, and the description of well-known functions and configurations that may unnecessarily obscure the gist of the present invention in the following description and the attached drawings will be omitted. The drawings introduced below are provided as examples so that those skilled in the art can sufficiently convey the idea of the present invention. Therefore, the present invention is not limited to the drawings presented below and may be embodied in other forms. In addition, the same reference numerals represent the same components throughout the specification. It should be noted that the same components in the drawings are represented by the same symbols wherever possible.

The present invention relates to a vacuum blood collection tube manufacturing device configured to prevent the generation of air bubbles during the process of injecting a reagent into a tube by allowing a reagent to be injected into a tube by an injection unit while the inside of the chamber is in a vacuum state by exhausting the internal air of the chamber to the outside of the chamber by a vacuum pump, and a vacuum blood collection tube manufacturing method using the same.

Hereinafter, with reference to the attached drawings, a vacuum blood collection tube manufacturing device according to the present invention and a vacuum blood collection tube manufacturing method using the same will be described in detail.

FIG. 1 is a drawing showing a vacuum blood collection tube manufacturing device according to an embodiment of the present invention, and FIGS. 2a to 2c are drawings showing side views of the vacuum blood collection tube manufacturing device according to an embodiment of the present invention.

According to the attached drawings 1 to 2c, a vacuum blood collection tube manufacturing device according to an embodiment of the present invention includes a chamber portion (100) in which one or more tubes (10) are accommodated therein, a vacuum pump (200) for discharging air inside the chamber portion (100) to the outside of the chamber portion (100) so that the inside of the chamber portion (100) becomes a vacuum state, a connecting portion (300) formed by a chamber pump pipe (310) configured to connect the chamber portion (100) and the vacuum pump (200), and an injection portion (400) configured to inject a reagent into one or more tubes (10) accommodated in the chamber portion (100).

A vacuum blood collection tube manufacturing device according to one embodiment of the present invention may further include a transport unit (600) for transporting a tray (200) containing one or more tubes (10) and an elevating unit (700) for elevating the chamber unit (100) to open and close the interior of the chamber unit (100).

The vacuum blood collection tube manufacturing device according to one embodiment of the present invention is configured to prevent problems such as the generation of bubbles in the one or more tubes (10) by allowing the one or more tubes (10) to be transferred to the lower portion of the chamber portion (100) by the transfer portion (600), and to lower the chamber portion (100) by the elevating portion (700) so that the one or more tubes (10) are accommodated in the chamber portion (100) and the interior of the chamber portion (100) is sealed, and then the vacuum pump (200) is driven to change the interior of the chamber portion (100) to a vacuum state, and then the reagent is injected by the injection portion (400).

That is, the vacuum blood collection tube manufacturing device according to one embodiment of the present invention is configured to prevent the problem of air bubbles being generated inside the one or more tubes (10) during the process of injecting the reagent into the one or more tubes (10) by making the environment for injecting the reagent into the one or more tubes (10) a vacuum state by the chamber part (100) and the vacuum pump (200).

FIG. 3 is a drawing showing a vacuum blood collection tube manufacturing device according to another embodiment of the present invention.

According to the attached drawing 3, a vacuum blood collection tube manufacturing device according to another embodiment of the present invention includes a chamber part (100) in which one or more tubes (10) are accommodated inside, a tank part (500) provided at a position connected to the chamber part (100), a vacuum pump (200) for discharging air inside the tank part (500) to the outside of the tank part (500) so that the inside of the tank part (500) becomes a vacuum state, a chamber tank pipe (320) configured to connect the chamber part (100) and the tank part (500), a tank pump pipe (330) configured to connect the tank part (500) and the vacuum pump (200), and a connection part (300) including a valve member (340) installed in the chamber tank pipe (320) to open and close the chamber tank pipe (320), and a valve member (340) configured to inject a reagent into one or more tubes (10) accommodated in the chamber part (100). An injection unit (400) is included.

A vacuum blood collection tube manufacturing device according to another embodiment of the present invention may further include a transport unit (600) for transporting a tray (200) containing one or more tubes (10) and an elevating unit (700) for elevating the chamber unit (100) to open and close the interior of the chamber unit (100).

According to another embodiment of the present invention, a vacuum blood collection tube manufacturing device is configured to prevent problems such as the generation of bubbles in the one or more tubes (10), by allowing the vacuum pump (200) to be driven so that the inside of the tank (500) changes into a vacuum state, allowing the one or more tubes (10) to be transferred to the lower part of the chamber (100) by the transfer unit (600), allowing the elevating unit (700) to lower the chamber (100) so that the one or more tubes (100) are accommodated in the chamber (100) and the inside of the chamber (100) is sealed, and then controlling the valve member (340) of the connecting unit (300) to be open so that the inside of the chamber (100) becomes a vacuum state, and then allowing the injection of a reagent by the injection unit (400).

That is, a vacuum blood collection tube manufacturing device according to another embodiment of the present invention is configured to prevent the problem of air bubbles being generated inside the one or more tubes (10) during the process of injecting a reagent into the one or more tubes (10) by making the environment for injecting a reagent into the one or more tubes (10) a vacuum state by the chamber portion (100), the tank portion (500) and the vacuum pump (200).

A vacuum blood collection tube manufacturing device according to another embodiment of the present invention may further include a control unit configured to control the operation of the vacuum pump (200), valve member (340), and injection unit (400).

That is, the control unit can control the vacuum pump (200) at the time of initial operation so that the interior of the tank unit (500) changes to a vacuum state, and when one or more tubes (10) are accommodated inside the chamber unit (100), the control unit can control the valve member (340) to open the chamber tank pipe (320) so that the interior of the chamber unit (100) changes to a vacuum state, and after the interior of the chamber unit (100) changes to a vacuum state, the control unit can control the injection of a reagent by the injection unit (400).

In addition, the process of controlling the vacuum pump (200) to change the inside of the tank part (500) into a vacuum state can be configured to be performed simultaneously with the process of injecting the reagent into one or more adjacent tubes into which the reagent has already been injected. To explain this in more detail, the control unit first controls the vacuum pump (200) to control the inside of the tank part (500) to change into a vacuum state, and when the inside of the chamber part (100) is sealed while one or more tubes (10) are accommodated inside the chamber part (100), the valve member (340) is controlled to an open state to control the inside of the chamber part (100) to change into a vacuum state. When the inside of the chamber part (100) is changed into a vacuum state, the valve member (340) is controlled to a closed state again and the vacuum pump (200) and the injection part (400) are controlled to change the inside of the tank part (500) into a vacuum state, and at the same time, the It is configured to inject a reagent into one or more tubes (10) located inside the chamber (100).

In this process, the internal pressure of the tank portion (500) when the valve member (340) is closed can be configured to be at least lower than the internal pressure of the tank portion (500) when the valve member (340) is open, and this can be understood as a phenomenon that occurs when the lowered pressure of the tank portion (500) by the vacuum pump (200) is shared with the pressure of the chamber portion (100) by opening the valve member (340), thereby changing the inside of the chamber portion (100) into a vacuum state.

In addition, the control unit may include a first detection sensor configured to detect and transmit the internal pressure of the chamber unit (100) and a second detection sensor configured to detect and transmit the internal pressure of the tank unit (500), and the control unit may be configured to determine the vacuum state of each of the chamber unit (100) and the tank unit (500) through the internal pressure of the chamber unit (100) transmitted from the first detection sensor and the internal pressure of the tank unit (500) transmitted from the second detection sensor.

The above control unit may be configured to determine whether it is okay to inject a reagent through the injection unit (400) through the internal pressure of the chamber unit (100) detected by the first detection sensor, and may be configured to determine whether the pressure of the tank unit (500) is transmitted to the chamber unit (100) to a level that can convert the internal pressure of the chamber unit (100) into a vacuum state when the chamber tank pipe (320) is opened by controlling the valve member (340) to an open state through the internal pressure of the tank unit (500) detected by the second detection sensor.

In other words, the control unit may be configured to allow reagent injection by the injection unit (400) after detecting whether the air pressure inside the chamber unit (100) detected by the first detection sensor is lower than a preset value, and may be configured to control the vacuum pump (200) to lower the air pressure inside the tank unit (500) at the same time as the reagent injection, and may be configured to lower the air pressure inside the tank unit (500) until the air pressure inside the tank unit (500) detected by the second detection sensor reaches a preset value.

That is, the control unit is configured to control the vacuum pump (200), the valve member (340), and the injection unit (400) based on the pressure of the chamber unit (100) and the tank unit (500) detected by the first detection sensor and the second detection sensor, thereby preventing the generation of air bubbles during the process of injecting a reagent into the tube (10) due to the vacuum state inside the chamber unit (100) not reaching an appropriate level.

FIG. 4 is a block diagram showing a method for manufacturing a vacuum blood collection tube using a vacuum blood collection tube manufacturing device according to one embodiment of the present invention.

According to the attached drawing 4, a method for manufacturing a vacuum blood collection tube using a vacuum blood collection tube manufacturing device according to one embodiment of the present invention may include a first receiving step (S11), a first pump driving step (S13), and a first reagent injection step (S15).

The first receiving step (S11) is a step in which one or more tubes (10) are received inside the chamber part (100). A separately configured transfer part (600) transfers a tray (200) containing the one or more tubes (10) to the lower part of the chamber part (100), and while the tray (200) is transferred to the lower part of the chamber part (100), a separately configured elevating part (700) lowers the chamber part (100) so that the inside of the chamber part (100) is sealed, thereby allowing one or more tubes (10) to be received inside the chamber part (100).

Since the first acceptance step (S11) is a step prior to changing the inside of the chamber part (100) into a vacuum state in the first pump driving step (S13), the chamber part (100) may be configured to further include a sealing detection sensor to detect the sealing state of the chamber part (100), and a method for manufacturing a vacuum blood collection tube according to an embodiment of the present invention may further include a step of detecting the sealing state of the chamber part (100) by the sealing detection sensor.

The above first pump driving step (S13) is a step in which the vacuum pump (200) is driven to cause the air inside the chamber part (100) to be discharged to the outside of the chamber part (100), thereby lowering the internal pressure of the chamber part (100) and changing it into a vacuum state.

Since the first pump driving step (S13) is a previous step for injecting a reagent into one or more tubes (10) accommodated inside the chamber part (100) in the first reagent injection step (S15), the control part configured to control the vacuum pump (200) may further include a first detection sensor configured to detect the internal air pressure of the chamber part (100), and the method for manufacturing a vacuum blood collection tube according to an embodiment of the present invention may further include a step configured to detect the internal air pressure of the chamber part (100) through the first detection sensor to determine whether the air pressure is appropriate for injecting a reagent into the one or more tubes (10).

The above first reagent injection step (S15) is a step of injecting a reagent into one or more tubes (10) accommodated in the chamber (100) after the interior of the chamber (100) has been changed to a vacuum state.

At this time, if one or more tubes (10) accommodated in the chamber portion (100) are configured in multiples, the injection portion (400) of the present invention is provided with a nozzle member to enable a certain amount of reagent to be evenly injected into the multiple tubes (10), so that the reagent can be configured to be evenly injected into the one or more tubes (10).

FIG. 5 is a block diagram showing a method for manufacturing a vacuum blood collection tube using a vacuum blood collection tube manufacturing device according to another embodiment of the present invention, and FIG. 6 is a block diagram showing a state in which a third pump driving step is added to a method for manufacturing a vacuum blood collection tube using a vacuum blood collection tube manufacturing device according to another embodiment of the present invention.

According to the attached drawings 5 and 6, a method for manufacturing a vacuum blood collection tube using a vacuum blood collection tube manufacturing device according to another embodiment of the present invention may include a second pump driving step (S21), a second receiving step (S23), a valve opening step (S25), and a second reagent injection step (S27).

The second pump driving step (S21) is a step of driving the vacuum pump (200) to discharge air inside the tank part (500) into the tank part (500), thereby lowering the internal pressure of the tank part (500) and changing it into a vacuum state. In the second pump driving step (S21), since the chamber part (100) configured to accommodate one or more tubes is in an open state, the valve member (340) configured to open and close the chamber tank pipe (320) connecting the chamber part (100) and the tank part (500) can be configured to be driven in a closed state.

The second receiving step (S23) is a step in which one or more tubes (10) are received inside the profit chamber part (100). A separately configured transfer part (600) transfers a tray (200) containing the one or more tubes (10) to the lower part of the chamber part (100), and while the tray (200) is transferred to the lower part of the chamber part (100), a separately configured elevating part (700) lowers the chamber part (100) so that the inside of the chamber part (100) is sealed, thereby allowing one or more tubes (10) to be received inside the chamber part (100).

Since the second acceptance step (S23) is a step prior to changing the inside of the chamber part (100) into a vacuum state in the valve opening step (S25), the chamber part (100) may be configured to further include a sealing detection sensor to detect the sealing state of the chamber part (100), and a method for manufacturing a vacuum blood collection tube according to another embodiment of the present invention may further include a step of detecting the sealing state of the chamber part (100) by the sealing detection sensor.

The above valve opening step (S25) is a step in which the internal pressure of the tank portion (500) changed to a vacuum state and the internal pressure of the chamber portion (100) are fused by controlling the valve member (340) configured to open and close the chamber tank pipe (320) to an open state, thereby changing the internal pressure of the chamber portion (100) to a vacuum state.

This valve opening step (S25) is to control the valve member (340) to open while the pressure of the tank part (500) is lowered in advance, thereby opening the chamber tank pipe (320) connecting the chamber part (100) and the tank part (500), thereby rapidly changing the inside of the chamber part (100) into a vacuum state.

The second reagent injection step (S27) is a step of injecting a reagent into one or more tubes (10) accommodated in the chamber (100) after the interior of the chamber (100) has been changed to a vacuum state.

At this time, if one or more tubes (10) accommodated in the chamber portion (100) are configured in multiples, the injection portion (400) of the present invention is provided with a nozzle member to enable a certain amount of reagent to be evenly injected into the multiple tubes (10), so that the reagent can be configured to be evenly injected into the one or more tubes (10).

A method for manufacturing a vacuum blood collection tube according to another embodiment of the present invention may further include a third pump driving step (S29) of controlling the valve member (340) to a sealed state and driving the vacuum pump (200) to allow air inside the tank part (500) to be discharged to the outside of the tank part (500) after the inside of the chamber part (100) has been changed to a vacuum state, thereby lowering the internal pressure of the tank part (500).

That is, the third pump driving step (S29) is to lower the pressure inside the tank section (500) to create a vacuum state before changing the inside of the chamber section (100) to a vacuum state, like the second pump driving step (S21).

Accordingly, the third pump driving step (S29) may be configured to proceed together with the second reagent injection step (S27), and in this case, the vacuum blood collection tube manufacturing method according to another embodiment of the present invention may be configured to be repeatedly driven in the order of the second pump driving step (S21), the second receiving step (S23), the valve opening step (S25), the second reagent injection step (S27), the third pump driving step (S29), the second receiving step (S23), the valve opening step (S25), the second reagent injection step (S27), and the third pump driving step (S29).

In other words, the second pump driving step (S21) may be configured to be performed only when the vacuum blood collection tube manufacturing device according to another embodiment of the present invention is first driven, and the second receiving step (S23), the valve opening step (S25), the second reagent injection step (S27), and the third pump driving step (S29) may be configured to be performed repeatedly.

Meanwhile, the air pressure inside the tank part (500) in the second pump driving step (S21) and the third pump driving step (S29) may be configured to have the same air pressure, but may be configured to be at least lower than the air pressure inside the tank part (500) in the valve opening step (S25).

This is because, in the valve opening step (S25), the valve member (340) is opened, and the chamber part (100) and the tank part (500) share their respective air pressures through the chamber tank pipe (320).

According to the present invention, the air inside the chamber is discharged to the outside of the chamber by a vacuum pump, and the inside of the chamber is in a vacuum state, and the reagent is injected into the tube by the injection unit, thereby preventing the generation of air bubbles during the process of injecting the reagent into the tube.

Although the above description has presented and described various embodiments of the present invention, the present invention is not necessarily limited thereto, and it will be apparent to those skilled in the art that various substitutions, modifications, and changes can be made without departing from the technical spirit of the present invention.

10: Tube 20: Tray
100: Chamber 200: Vacuum pump
300 : Connection
310: Chamber pump pipe 320: Chamber tank pipe
330: Tank pump pipe 340: Valve member
400 : Injection part 500 : Tank part
600: Transport section 700: Lift section

Claims (10)

delete In a vacuum blood collection tube manufacturing device for manufacturing a vacuum blood collection tube,
A chamber portion (100) in which one or more tubes (10) are accommodated inside;
A tank section (500) provided at the above chamber section (100) and the contact position;
A vacuum pump (200) that discharges air inside the tank (500) to the outside of the tank (500) so that the inside of the tank (500) becomes a vacuum state;
A chamber tank pipe (320) configured to connect the chamber part (100) and the tank part (500), a tank pump pipe (330) configured to connect the tank part (500) and the vacuum pump (200), and a connecting part (300) including a valve member (340) installed in the chamber tank pipe (320) to open and close the chamber tank pipe (320); and
An injection unit (400) configured to inject a reagent into one or more tubes (10) accommodated in the chamber unit (100);
Includes,
It includes a control unit configured to control the operation of the above vacuum pump (200), valve member (340) and injection unit (400).
The above control unit,
At the first operation, the vacuum pump (200) is controlled so that the inside of the tank part (500) changes to a vacuum state.
A vacuum blood collection tube manufacturing device characterized in that when one or more tubes (10) are accommodated inside the chamber part (100), the valve member (340) is controlled to open the chamber tank pipe (320) so that the inside of the chamber part (100) changes to a vacuum state, and then a reagent is injected.
In the second paragraph,
A transport unit (600) for transporting a tray (200) containing one or more tubes (10); and
A lifting unit (700) that lifts the chamber unit (100) to open and close the interior of the chamber unit (100);
A vacuum blood collection tube manufacturing device characterized by further including:
delete delete In the second paragraph,
In the above control unit,
A first detection sensor configured to detect and transmit the internal pressure of the chamber (100); and
A second detection sensor configured to detect and transmit the internal pressure of the tank portion (500);
Includes:
The above control unit,
A vacuum blood collection tube manufacturing device characterized in that it is configured to detect the vacuum state of each of the chamber part (100) and the tank part (500) through the internal pressure of the chamber part (100) transmitted from the first detection sensor and the internal pressure of the tank part (500) transmitted from the second detection sensor.
delete In a method for manufacturing a vacuum blood collection tube using a vacuum blood collection tube manufacturing device comprising the second clause,
A second pump driving step (S21) for driving a vacuum pump (200) to discharge air inside the tank part (500) to the outside of the tank part (500), thereby lowering the internal pressure of the tank part (500) and changing it into a vacuum state;
A second receiving step (S23) in which one or more tubes (10) are received inside the chamber portion (100);
A valve opening step (S25) in which the internal pressure of the tank portion (500) changed to a vacuum state and the internal pressure of the chamber portion (100) are fused by controlling the valve member (340) configured to open and close the chamber tank pipe (320) to an open state so that the internal pressure of the chamber portion (100) is changed to a vacuum state;
After the interior of the chamber part (100) is changed to a vacuum state, a second reagent injection step (S27) for injecting a reagent into one or more tubes (10) accommodated in the chamber part (100); and
After the inside of the chamber part (100) is changed to a vacuum state, the valve member (340) is controlled to a sealed state and the vacuum pump (200) is driven to lower the internal pressure of the tank part (500) by causing the air inside the tank part (500) to be discharged to the outside of the tank part (500), thereby a third pump driving step (S29);
A method for manufacturing a vacuum blood collection tube, characterized in that it includes:
delete In Article 8,
The internal pressure of the tank part (500) of the second pump driving stage (S21) and the third pump driving stage (S29) is
A method for manufacturing a vacuum blood collection tube, characterized in that the vacuum blood collection tubes are configured to have the same pressure, but are at least lower than the pressure inside the tank portion (500) of the valve opening step (S25).

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