KR102388173B1 - Composition for teeth whitening containing hydroxy apatite and lettuce extract - Google Patents

Abstract

The present invention relates to a tooth whitening composition comprising hydroxyapatite and lettuce extract, and the tooth whitening composition comprising hydroxyapatite and lettuce extract according to the present invention comprises a natural extract such as hydroxyapatite and lettuce extract. By using it, it can be useful as a composition for teeth whitening because not only human stability is excellent, but also a tooth whitening effect is excellent.

Description

Composition for teeth whitening containing hydroxy apatite and lettuce extract, comprising hydroxyapatite and lettuce extract

The present invention relates to a tooth whitening composition comprising hydroxyapatite and a lettuce extract.

As interest in beauty increases in modern society, interest in the aesthetic aspect of teeth, which determines a person's impression, is also increasing. In addition, as interest in aesthetic dentistry increases due to the development of dental technology and the prevention of two major oral diseases such as dental caries and periodontal disease, patients visiting the dentist have recently improved not only the treatment of oral diseases but also the aesthetics of teeth. I prefer tooth whitening that can be done.

The main factors for performing teeth whitening are tooth discoloration and discoloration. Among them, tooth discoloration is when the color of the teeth is outside the normal range. The causes of tooth discoloration can be divided into internal factors and external factors. Internal factors may occur due to discoloration due to tetracycline deposition, trauma, or age increase, and external factors may be caused by cigarettes, food, and beverages.

The type of teeth whitening is a professional whitening procedure performed by a professional in the dentist, who is trained by a professional and then directly performed, or a person who directly obtains a tooth whitening product from the market without receiving an expert's education or prescription and performs it at home It is divided into whitening, etc.

Early teeth whitening originated from the application of white material to the surface of innumerable teeth and filling the inner surface, and in 1868, the whitening of vital teeth was first known. Hydrogen peroxide was used. Materials such as hydrogen peroxide, urea peroxide, and sodium perborate are used as the main ingredients of the currently used tooth whitening agent. Among them, hydrogen peroxide plays a role in decomposing into water and active oxygen, and the active oxygen generated in this way is used as a coloring material that causes tooth discoloration and It causes a chemical reaction to show the effect of teeth whitening. However, while research on chemically synthesized tooth whitening agents is being actively conducted, there are few previous studies and verification of their effectiveness on natural tooth whitening to date.

Accordingly, the present inventors confirmed that hydroxyapatite and natural extracts have a tooth whitening effect and completed the present invention.

Korean Patent No. 10-1660467

An object of the present invention is to provide a composition for whitening teeth.

In order to achieve the above object,

The present invention is hydroxyapatite (hydroxy apatite); And it provides a composition for teeth whitening comprising a lettuce extract.

The composition for teeth whitening comprising hydroxyapatite and lettuce extract according to the present invention uses natural extracts such as hydroxyapatite and lettuce extract, so that not only human stability is excellent, but also teeth whitening effect is excellent. It may be useful as a composition for

Hereinafter, the present invention will be described in detail.

Composition for teeth whitening

The present invention is hydroxyapatite (hydroxy apatite); And it provides a composition for teeth whitening comprising a lettuce extract.

In the composition of the present invention, the composition may include a soybean hull extract or a dermis extract, respectively, or a mixture thereof.

In the composition of the present invention, the composition may contain 4 to 10 parts by weight of hydroxy apatite based on 100 parts by weight of the lettuce extract, and preferably 6 to 8 parts by weight of hydroxy apatite based on 100 parts by weight of the lettuce extract. It may contain parts by weight.

In the composition of the present invention, the composition may further include one or more extracts of 55 to 85 parts by weight of the bean pod extract and 25 to 60 parts by weight of the dermis extract based on 100 parts by weight of the lettuce extract, preferably 100 parts by weight of the lettuce extract It may further include at least one extract of 60 to 80 parts by weight of the bean pod extract and 35 to 50 parts by weight of the dermis extract.

In one embodiment of the present invention, the composition is toothpaste, mouthwash, mouthwash, gum, candy, mouth spray. It may be oral ointment, oral varnish or mouthwash, preferably toothpaste.

In the composition of the present invention, the extract may be extracted with water, an alcohol having 1 to 4 carbon atoms, or a mixed solvent thereof, preferably extracted with distilled water, but is not limited thereto.

In one embodiment of the present invention, the composition may further include a foaming agent, a wetting agent, a preservative, a sweetener, a flavoring agent, a thickener and a solvent.

In one embodiment of the present invention, sodium cocoyl glutamate, which is a natural plant extract derived from coconut, was used as the foaming agent, and it may be used as a foaming agent for cleaning and foaming in the oral cavity, but is not limited thereto.

In one embodiment of the present invention, vegetable glycerin is used as the wetting agent, prevents moisture evaporation, has strong moisture absorption, and has an effect of preventing dry mouth when used in the oral cavity, but is not limited thereto.

In one embodiment of the present invention, grapefruit seed extract having natural sterilization, disinfection, and preservative effects was used as the preservative, but is not limited thereto.

In one embodiment of the present invention, xylitol or enzyme-treated stevia, which is a naturally-derived sweetener, may be used alone or in combination instead of an artificial sweetener in order to sweeten the sweetener.

In one embodiment of the present invention, one or more of eucalyptus extract, pogongyeong extract, citrus mint flavor and peppermint oil may be used as the flavoring agent to give a natural taste and flavor.

In one embodiment of the present invention, the thickener is for maintaining a constant viscosity, and a thickener of a natural component may be used, preferably xanthan gum, but is not limited thereto.

In one embodiment of the present invention, purified water may be used as the solvent.

The present invention will be described in more detail through the following examples. However, the following examples are only intended to embody the contents of the present invention, and the present invention is not limited thereto.

<Preparation Example 1> Preparation of lettuce extract

After drying and pulverizing the lettuce, 15 times the volume of distilled water was used to 1 kg of the ground lettuce and extracted at 50° C. for 24 hours. After repeating the above process 3 times, the extract was filtered through Whatman No. 1 filter paper (GE Healthcare, Buckinghamshire, UK) and the sample was evaporated in a vacuum rotary evaporator. Then, the concentrated extract was freeze-dried in a freeze dryer to obtain a lettuce extract. The lettuce extract was stored at -20°C until use.

<Preparation Example 2> Preparation of bean pod extract

After drying and pulverizing the bean pods, 1 kg of the pulverized bean pods were extracted with 15 times the volume of distilled water at 50° C. for 24 hours. After repeating the above process 3 times, the extract was filtered through Whatman No. 1 filter paper (GE Healthcare, Buckinghamshire, UK) and the sample was evaporated in a vacuum rotary evaporator. Then, the concentrated extract was freeze-dried in a freeze dryer to obtain a bean pod extract. The bean pod extract was stored at -20°C until use.

<Preparation Example 3> Preparation of dermis (tangerine peel) extract

After drying and pulverizing the dermis, 1 kg of the pulverized dermis was extracted with 15 times the volume of distilled water at 50° C. for 24 hours. After repeating the above process 3 times, the extract was filtered through Whatman No. 1 filter paper (GE Healthcare, Buckinghamshire, UK) and the sample was evaporated in a vacuum rotary evaporator. Then, the concentrated extract was freeze-dried in a freeze dryer to obtain a dermis extract. Dermal extracts were stored at -20°C until use.

<Example> Preparation of a composition for teeth whitening

A composition for teeth whitening was prepared by preparing hydroxyapatite, lettuce extract, soybean pod extract and dermis extract with the composition shown in Table 1 below, and preparing the other ingredients shown in Table 2 below.

hydroxyapatite lettuce extract bean pod extract Dermal Extract Example 1 5g 70g - - Example 2 5g 70g 50g - Example 3 5g 70g - 30g Example 4 5g 70g 50g 30g Comparative Example 1 5g - - - Comparative Example 2 - 70g - - Comparative Example 3 - - 50 - Comparative Example 4 - - - 30g

division Raw material name purpose of mixing One Sodium Cocoyl Glutamate foaming agent 2 vegetable glycerin wetting agent 3 Grapefruit Seed Extract preservative 4 xylitol sweetener 5 Enzyme-treated Stevia sweetener 6 Eucalyptus Extract flavoring agent 7 Pogongyoung extract flavoring agent 8 Citrus mint flavor flavoring agent 9 peppermint oil flavoring agent 10 xanthan gum thickener 11 Purified water solvent

<Experimental Example 1> Teeth whitening effect test on tooth specimens

The gel-like mixture obtained by uniformly mixing tobacco dust, coffee, black tea powder and sugar, which can cause extrinsic discoloration of teeth, is placed in a container equipped with a rotating plate at the bottom, After the rotation plate was fixed, the rotation plate was rotated for 72 hours to induce staining of the tooth specimen. After that, after the staining-induced tooth specimen is dried in the shade for 2 days, the tooth whitening composition of Examples 1 to 4 and Comparative Examples 1 to 4 is used to reciprocate 90 times per minute. A fixed toothbrush was applied and the colored tooth specimen was artificially polished for 20 minutes. Before and after the artificial polishing, the whiteness was measured using a colorimeter (SZ, Nippon Denshoku), and the degree of whiteness increase (ΔL) before and after polishing is shown in Table 3 below.

Whiteness increase (ΔL) Comparative Example 1 26.9 Comparative Example 2 25.7 Comparative Example 3 24.5 Comparative Example 4 23.6 Example 1 59.7 Example 2 60.2 Example 3 60.8 Example 4 70.1

As a result of confirming the tooth whitening effect experiment on the tooth specimen, as shown in Table 3 above, the hydroxyapatite, lettuce extract, bean pod extract or dermis extract of Comparative Examples 1 to 4 was used alone, in Example 1 When one or more of the hydroxyapatite, lettuce extract, bean pod extract, and dermis extract of Example 4 were mixed and used, it was confirmed that the whiteness before and after polishing was significantly increased.

<Experimental Example 2> Teeth whitening effect test

The whitening effect was evaluated by directly using the tooth whitening compositions of Examples 1 to 4 and Comparative Examples 1 to 4 for 2 months. After selecting 80 people who had undergone extrinsic coloration, measure the color tone of the labial surface of the incisor using a colorimeter in a room with a constant lighting device before starting the experiment. By sorting, each toothpaste composition was dispensed and brushed according to the usual brushing habits. In order to confirm the increase in the brightness of teeth, 10 types that are easy to identify sensibly out of 24 standard standards for each brightness of the color scale were selected, and evaluation scores were added from 1 point to 10 points in the order of the brightness value to each. . Before using the toothpaste, the tooth brightness value for each group was evaluated to the first decimal place based on the above criteria, and after evaluating the brightness value after brushing for 2 months, the increase rate of the average brightness value compared to the brightness value before the experiment was calculated.

average value
(before experiment) average value
(after use) Brightness increase rate
(%) Comparative Example 1 3.7 5.3 43 Comparative Example 2 3.6 4.5 25 Comparative Example 3 3.8 4.8 26 Comparative Example 4 3.7 4.9 32 Example 1 3.7 6.3 70 Example 2 3.6 6.2 72 Example 3 3.7 6.4 73 Example 4 3.8 7.1 87

As a result of evaluating the whitening effect by directly using the tooth whitening compositions of Examples 1 to 4 and Comparative Examples 1 to 4 for 2 months, as shown in Table 4, hydroxyapatite and lettuce extracts of Comparative Examples 1 to 4 , when using a mixture of one or more of the hydroxyapatite, lettuce extract, bean pod extract and dermis extract of Examples 1 to 4, compared to the case of using the bean pod extract or the dermis extract alone, the brightness increase rate is significantly superior Confirmed.

So far, with respect to the present invention, the preferred embodiments have been looked at. Those of ordinary skill in the art to which the present invention pertains will understand that the present invention can be implemented in a modified form without departing from the essential characteristics of the present invention. Therefore, the disclosed embodiments are to be considered in an illustrative rather than a restrictive sense. The scope of the present invention is indicated in the claims rather than the foregoing description, and all differences within the scope equivalent thereto should be construed as being included in the present invention.

Claims (6)

hydroxy apatite; lettuce extract; soybean hull extract; And a tooth whitening composition comprising a dermis extract. delete The method of claim 1,
The composition for teeth whitening, characterized in that it contains 4.75-5.25 parts by weight of hydroxy apatite, 47.5-52.5 parts by weight of bean pod extract, and 28.5-31.5 parts by weight of dermis extract based on 70 parts by weight of the lettuce extract. delete The method of claim 1,
The composition is a tooth whitening composition, characterized in that at least one selected from the group consisting of toothpaste, mouthwash, mouthwash, gum, candy, mouth spray, oral ointment, oral varnish, and mouthwash. 6. The method of claim 5,
The composition is a tooth whitening composition, characterized in that the toothpaste.