KR102233917B1 - Endometrial suction biopsy sampler - Google Patents

Abstract

The present invention relates to an endometrial suction biopsy sampler, comprising: a sampler body having an insertion end inserted into the uterine cavity and mounted therein, at least one specimen recovery hole penetrating around the insertion end, and a passage communicating with the specimen recovery hole therein; a guide rod that reciprocates to be inserted or withdrawn toward the insertion end along the passage of the sampler body, and generates negative pressure in the passage of the insertion end to suck the specimen of the endometrium recovered in the passage of the insertion end; and a stopper locking or unlocking the guide rod to and from the sampler body.

Description

Endometrial aspiration biopsy sampler {ENDOMETRIAL SUCTION BIOPSY SAMPLER}

The present invention relates to an endometrial aspiration biopsy sampler.

Due to the Westernized lifestyle pattern, the incidence of endometrial cancer in Korea is similar to that of Western countries.

Many middle-aged women have metabolic syndrome diseases that are combined with obesity, high blood pressure, and diabetes, and it has been reported that the incidence of endometrial endometrial hyperplasia and endometrial cancer in these women is quite high.

In gynecology, the endometrial examination is conducted in two ways: an ultrasound examination and a biopsy. The ultrasound examination is an imaging examination that estimates the state of the endometrium based on the thickness and shape of the endometrium. If an endometrial abnormality is suspected A confirmation test is required, and a biopsy is performed through endometrial sofa surgery.

Endometrial sofa surgery does not perform general anesthesia, but requires a certain degree of anesthesia, and it is somewhat burdensome for patients to test without discomfort. As an alternative method, a relatively accurate and safe minimally invasive test has been devised and used. This is a biopsy method.

There are several types of endometrial aspiration samplers used for this aspiration endometrial biopsy. However, many types of endometrial aspiration samplers are currently being developed and used, but the currently commercialized products require considerable improvement and are uncomfortable.

For example, in the conventional endometrial suction sampler, negative pressure is generated in the sampler by the sampler and the guide rod to collect a sample of the lumen of the uterus, but when the guide rod inserted into the sampler is pulled out from the sampler to create negative pressure, the negative pressure generated in the sampler is As a result, there is a problem that the guide rod returns to its original position, so that the sample cannot be collected well.In this case, the sampler body must be rotated or moved back and forth while pulling the guide rod in the withdrawal direction, making the collection process difficult.

In addition, in the conventional endometrial suction sampler, since the sampler body in which the guide rod is provided to be inserted or withdrawn has a linear shape, the sampler must be mounted in the lumen according to the linear shape of the sampler itself. Therefore, when the uterine lumen has a structure that is inclined back and forth, such as anterior or posterior conduit, it is difficult to properly mount the sampler, and there is a fear of causing damage to the anterior or posterior wall of the uterus.

US Patent Publication US6,042,552

The present invention is to solve the above problems, and an object of the present invention is to provide an endometrial aspiration biopsy sampler capable of easily collecting a specimen, thereby improving the convenience of a practitioner, and safely performing an examination.

In addition, another object of the present invention is to bend or unfold the insertion end of the sampler body in response to the shape of the uterine lumen, thereby minimizing the incidence of intrauterine damage due to biopsy, and being able to safely insert and mount in the uterine lumen. To provide an endometrial aspiration biopsy sampler.

An object of the present invention is a sampler body having an insertion end inserted and mounted into the uterine lumen, at least one specimen recovery hole formed through the circumference of the insertion end, and a passage communicating with the specimen recovery hole therein; A guide rod which reciprocates along the passage of the sampler body so as to be inserted or withdrawn toward the insertion end, and generates a negative pressure in the passage of the insertion end to suck a sample of the endometrial recovered through the passage of the insertion end; And a stopper that locks or unlocks the guide rod to the sampler body, and may be achieved by an endometrial suction biopsy sampler.

Here, the stopper may include a locking groove formed through a predetermined length in an outer periphery of the sampler body along a moving direction of the guide rod; And a locker provided to be retractable in the guide rod and locked or unlocked in the locking groove.

In the locking groove, a circumference of the locking groove in the direction of insertion of the guide rod is formed perpendicular to the insertion direction of the guide rod, and a circumference of the locking groove in the withdrawal direction of the guide rod is of the guide rod. It may be formed to be inclined toward the drawing direction.

The rocker includes: a rocker body having a locking jaw formed perpendicular to an insertion direction of the guide rod, and a curved portion formed to be curved in an arc shape from the locking jaw toward a drawing direction of the guide rod; And a support rib for stationery the locker main body to the guide rod so that the locker main body is caught or released from the locking groove.

It is mounted on the outer periphery of the guide rod, it may further include a packing member for packing between the guide rod and the sampler body.

It may further include a guide wire provided on the sampler body and configured to change the shape of the insertion end corresponding to the shape of the uterine lumen.

The sampler body may include a flexible material.

It may further include a blade provided in at least one area around the circumference of the specimen recovery hole, and for collecting a specimen from the lumen of the uterus.

The specimen recovery holes are provided in a pair, and the pair of specimen recovery holes are arranged at a certain angle around the insertion end, and a blade provided in one specimen recovery hole and a blade provided in the other specimen recovery hole are Each of them may be disposed around a circumference positioned in opposite directions between one specimen recovery hole and the other specimen recovery hole.

A plurality of scales displayed at regular intervals along the longitudinal direction of the sampler body may be further included on the outer periphery of the sampler body.

According to the present invention, since a specimen can be easily collected, the convenience of the operator can be improved, and the inspection can be performed safely.

In addition, the insertion end of the sampler body can be bent or unfolded according to the shape of the uterine lumen to minimize the incidence of intrauterine damage due to a biopsy, and can be safely inserted and mounted in the uterine lumen.

1 is an exploded perspective view of an endometrial suction biopsy sampler according to an embodiment of the present invention,
FIG. 2 is a cross-sectional view showing a state before negative pressure is maintained in the endometrial aspiration biopsy sampler of FIG. 1;
3 is a cross-sectional view showing a state in which the sampler body and the guide rod are locked by the stopper of FIG. 1;
4 is a cross-sectional view taken along line AA′ of FIG. 1;
FIG. 5A is an enlarged plan view of part “B” of FIG. 1, and FIG. 5B is an enlarged plan view of part “C” of FIG. 1.

Advantages and features of the present invention, and a method of achieving them will become apparent with reference to the embodiments described below in detail together with the accompanying drawings. However, the present invention is not limited to the embodiments disclosed below, but may be implemented in a variety of different forms. It is provided to fully inform the skilled person of the scope of the present invention, and the present invention is only defined by the scope of the claims.

The terms used in the present specification are for describing exemplary embodiments and are not intended to limit the present invention. In this specification, the singular form also includes the plural form unless specifically stated in the phrase. As used herein, “comprises” and/or “comprising” do not exclude the presence or addition of one or more other elements other than the mentioned elements. Throughout the specification, the same reference numerals refer to the same elements, and "and/or" includes each and all combinations of one or more of the mentioned elements. Although "first", "second", and the like are used to describe various elements, it goes without saying that these elements are not limited by these terms. These terms are only used to distinguish one component from another component. Therefore, it goes without saying that the first component mentioned below may be the second component within the technical idea of the present invention.

Unless otherwise defined, all terms (including technical and scientific terms) used in the present specification may be used with meanings that can be commonly understood by those of ordinary skill in the art to which the present invention belongs. In addition, terms defined in a commonly used dictionary are not interpreted ideally or excessively unless explicitly defined specifically.

Hereinafter, embodiments of the present invention will be described in detail with reference to the accompanying drawings.

1 to 5 illustrate an endometrial suction biopsy sampler according to an embodiment of the present invention.

As shown in these figures, the endometrial suction biopsy sampler 1 according to an embodiment of the present invention includes a sampler body 10, a guide rod 40, and a stopper 50.

The sampler body 10 forms a passage 11 therein, and has a hollow tube shape in which an opening on one side is blocked.

The sampler body 10 includes a flexible material to be bent or unfolded in a desired shape.

The sampler body 10 may have a length greater than or equal to a distance from the vagina to the lumen of the uterus in consideration that the operator must hold the sampler body 10 outside the vagina and perform an insertion procedure.

The sampler body 10 may have a circular cross-sectional shape so as not to damage the lumen of the uterus when inserted, and to minimize foreign body sensation.

Further, on the outer periphery of the sampler main body 10, a scale 13 is displayed so that the operator can easily visually grasp how much of the sampler main body 10 has been inserted into the body. The scales 13 are displayed at regular intervals along the longitudinal direction of the sampler body 10.

In addition, the insertion end 15 in which the opening on one side of the sampler body 10 is blocked is inserted into the uterine lumen and mounted.

A pair of specimen collection holes 21a and 21b are formed around the insertion end 15 so as to communicate with the passage 11 at a predetermined angle.

The specimen collection holes 21a and 21b have a rectangular cross-sectional shape.

Here, in the present embodiment, it is shown that a pair of specimen recovery holes 21a and 21b are provided, but one or three or more specimen recovery holes may be provided. In addition, in the present embodiment, although the specimen recovery holes 21a and 21b are shown to have a rectangular cross-sectional shape, the present invention is not limited thereto, and the specimen recovery hole may have a polygonal cross-sectional shape other than a circle, an ellipse, and a square.

Further, around the specimen collection holes 21a and 21b, planer knife-shaped blades 25a and 25b for collecting specimens from the uterine lumen are provided.

In this way, by providing the blades 25a and 25b around the specimen collection holes 21a and 21b, as the sampler body 10 is rotated or moved in the front and rear direction, more specimens can be scraped and collected. There will be.

And, the blade (25a) provided in the one side specimen recovery hole (21a) and the blade (25b) provided in the other side specimen recovery hole (21b) are, respectively, one side as shown in Figure 5 (a) and (b) It is located around the opposite direction of the specimen recovery hole 21a and the other specimen recovery hole 21b.

As described above, by arranging the blades 25a and 25b provided in the specimen recovery holes 21a and 21b in opposite directions, the recovery rate of the specimen can be improved.

Here, although not shown, the blade may be provided along the entire circumference of the specimen recovery hole.

In addition, the endometrial suction biopsy sampler 1 according to an embodiment of the present invention further includes a pair of guide wires 30.

A pair of guide wires 30 face each other with the passage 11 interposed therebetween, and are built in along the longitudinal direction of the sampler body 10. The pair of guide wires 30 has a length greater than or equal to the length of the sampler body 10 so that the operator can hold it by hand.

Accordingly, as the operator holds the pair of guide wires 30 from the outside of the vagina with hands and tensions or relaxes, the insertion end 15 is bent or unfolded at a desired angle in response to the shape of the uterine lumen. You can transform it.

Here, in the present embodiment, although it is shown that a pair of guide wires 30 are provided, the present invention is not limited thereto, and one or three or more guide wires may be provided.

The guide rod 40 has a rod shape of a circular cross-section, and moves reciprocally along the passage 11 of the sampler body 10 so as to be inserted or withdrawn toward the insertion end 15.

The guide rod 40 is inserted into the passage 11 of the insertion end 15 and generates a negative pressure in the passage 11 between the insertion end 15 and the tip end of the guide rod 40. Accordingly, when the guide rod 40 is withdrawn from the sampler body 10, the uterus recovered in the passage 11 between the insertion end 15 and the tip end of the guide rod 40 through the specimen collection holes 21a and 21b It can be obtained by aspirating a sample of the inner membrane.

Meanwhile, the endometrial suction biopsy sampler 1 according to an embodiment of the present invention may further include a packing member 45.

The packing member 45 has an O-ring shape and is mounted on the outer periphery of the guide rod 40. The packing member 45 is slidably in close contact with the inner circumference of the sampler body 10 to pack between the guide rod 40 and the sampler body 10.

In this way, by further including the packing member 45, it is possible to more reliably form a negative pressure in the passage 11 between the insertion end 15 and the guide rod 40.

The stopper 50 locks or unlocks the guide rod 40 inserted into the sampler body 10 to limit the insertion of the guide rod 40. The stopper 50 includes a locking groove 51 and a rocker 61.

Hereinafter, for convenience of explanation, a direction in which the guide rod 40 is inserted into the sampler body 10 is referred to as an insertion direction, and a direction in which the guide rod 40 is drawn out from the sampler body 10 is referred to as a drawing direction.

The locking groove 51 has a rectangular cross-sectional shape, and is formed through the outer periphery of the sampler body 10 in a predetermined length and width along the moving direction of the guide rod 40, for example, the insertion direction and the withdrawal direction.

As shown in FIG. 3, the circumference of the locking groove 51 facing the insertion direction of the guide rod 40 is formed with a vertical portion 53 perpendicular to the insertion direction of the guide rod 40.

In addition, the circumference of the locking groove 51 facing the withdrawal direction of the guide rod 40 is formed with an inclined portion 55 inclined toward the withdrawal direction of the guide rod 40.

The locker 61 is provided in the guide rod 40 so as to be able to be pulled in and out, and is jammed or released from the locking groove 51. The rocker 61 includes a rocker body 63 and a support rib 69.

The rocker body 63 has a size smaller than the width and length of the locking groove 51. The rocker body 63 includes a locking projection 65 formed perpendicular to the insertion direction of the guide rod 40, and a curved portion formed to be curved in an arc shape from the locking projection 65 toward the withdrawal direction of the guide rod 40 ( 67). The locking protrusion 65 of the rocker body 63 is disposed toward the insertion end 15, and the curved portion 67 is disposed toward the opposite direction of the insertion end 15.

Accordingly, when the locking projection 65 of the locker 61 is held in the vertical portion 53 of the locking groove 51, the guide rod 40 is locked while restricting movement in the insertion direction. On the contrary, when the guide rod 40 is moved in the withdrawal direction while the rocker 61 is held in the locking groove 51, the curved portion 67 of the rocker 61 becomes the inclined portion 55 of the locking groove 51. ), and the rocker 61 is disengaged from the locking groove 51 while approaching the guide rod 40, so that the guide rod 40 smoothly moves along the inner circumference of the sampler body 10 in the drawing direction. Will move.

The support rib 69 has the shape of a cantilevered beam and is stationary to the guide rod 40. In this embodiment, the support rib 69 is stationery around one side of the recessed groove 43 formed in the outer circumference of the guide rod 40. The support rib 69 generates an elastic force so that its free end is spaced apart from the guide rod 40.

Meanwhile, a rocker body 63 is provided at the free end of the support rib 69. Accordingly, when no external force acts on the rocker body 63, the rocker body 63 is held in the locking groove by the elastic force of the support rib 69. Conversely, when an external force acts on the rocker body 63, the support rib 69 pivots toward the recess groove 43 and is released from the locking groove.

In this way, by including the stopper 50, the guide rod 40 is drawn out from the sampler body 10 in the withdrawal direction, and the passage 11 between the insertion end 15 of the sampler body 10 and the guide rod 40 ) After the negative pressure is formed, and the rocker 61 is held in the locking groove 51, the guide rod 40 does not move in the insertion direction, and the insertion end 15 and the guide rod of the sampler body 10 The negative pressure is maintained in the passage 11 between the distal ends of the 40, and the sampler body 10 is rotated in the uterine lumen or moved forward and backward, so that the specimen can be easily collected.

According to this configuration, after grasping the shape of the uterine lumen using ultrasound or the like, the pair of guide wires 30 are tensioned or relaxed to form the sampler body 10 in a shape corresponding to the target portion of the uterine lumen photographed by ultrasound. ) Of the insertion end 15 is deformed.

Then, in a state in which the guide rod 40 is inserted into the sampler body 10 so that the tip end of the guide rod 40 is located in the passage 11 of the insertion end 15 of the sampler body 10, the sampler body 10 ) Of the insertion end 15 is inserted into the target site of the uterine lumen. In this case, the rocker 61 may be positioned between the insertion end 15 of the sampler body 10 and the locking groove 51 as shown in FIG. 2. In addition, the operator can easily grasp the insertion depth of the sampler body 10 through the scale 13 displayed on the sampler body 10.

Subsequently, when the guide rod 40 is pulled out from the sampler body 10 in the withdrawal direction and the rocker 61 is held in the locking groove 51 as shown in FIG. 3, the guide rod 40 is provided on the outer circumference of the guide rod 40. A negative pressure is formed in the passage 11 between the insertion end 15 of the sampler body 10 and the tip end of the guide rod 40 by the packing member 45.

When negative pressure is formed in the passage 11 between the insertion end 15 of the sampler body 10 and the tip end of the guide rod 40, when the sampler body 10 is rotated or moved in the forward and backward directions, each specimen is collected. The blades 25a and 25b provided in the balls 21a and 21b collect samples from the target area of the uterine lumen. At this time, as the rocker 61 is held in the locking groove 51, the guide rod 40 does not move in the insertion direction, so that between the insertion end 15 of the sampler body 10 and the guide rod 40 It is possible to easily collect a sample while the negative pressure is maintained in the passage 11 of the.

The specimens collected by the blades 25a and 25b are collected through the respective specimen collection holes 21a and 21b into the passage 11 between the insertion end 15 of the sampler body 10 and the guide rod 40.

When the collection of the specimen is complete, the sampler body 10 is withdrawn from the uterine lumen, and the guide rod 40 is separated from the sampler body 10, so that the recovered specimen can be obtained in the sampler body 10.

As described above, according to the present invention, by including the stopper 50 for locking the guide rod 40 to the sampler body 10, the passage between the insertion end 15 of the sampler body 10 and the guide rod 40 (11) The sampler body 10 is rotated in the lumen of the uterus or moved back and forth in the uterine lumen while the negative pressure is maintained, allowing the sample to be easily collected, improving the convenience of the operator and enabling safe testing. do.

In addition, by providing a guide wire 30 on the sampler body 10, the insertion end 15 of the sampler body 10 is bent or unfolded in response to the shape of the uterine lumen, thereby minimizing the incidence of intrauterine damage due to biopsy. And, it can be safely inserted into the lumen of the uterus at a desired location.

In the above, embodiments of the present invention have been described with reference to the accompanying drawings, but those of ordinary skill in the art to which the present invention pertains can be implemented in other specific forms without changing the technical spirit or essential features. You will be able to understand. Therefore, the embodiments described above are illustrative in all respects, and should be understood as non-limiting.

1: Endometrial suction tissue spot sampler
10: sampler body
11: passage
13: graduation
15: insertion end
21a, 21b: sample recovery hole
25a, 25b: blade
30: guide wire
40: guide rod
45: packing member
50: stopper
51: locking groove
61: locker

Claims (10)

A sampler body having an insertion end inserted into and mounted into the uterine lumen, at least one specimen recovery hole formed through the circumference of the insertion end, and having a passage communicating with the specimen recovery hole therein;
A guide rod that reciprocates along the passage of the sampler body so as to be inserted or withdrawn toward the insertion end, and generates a negative pressure in the passage of the insertion end to suck a sample of the endometrial recovered through the passage of the insertion end; And
Endometrial suction biopsy sampler comprising a stopper for locking or unlocking the guide rod to the sampler body. The method of claim 1,
The stopper,
A locking groove formed through a predetermined length in an outer circumference of the sampler body along the moving direction of the guide rod; And
An endometrial suction biopsy sampler provided to be retractable in the guide rod and including a locker that is hooked or released from the locking groove. The method of claim 2,
The locking groove,
The circumference of the locking groove toward the insertion direction of the guide rod is formed perpendicular to the insertion direction of the guide rod, and the circumference of the locking groove toward the withdrawal direction of the guide rod is inclined toward the withdrawal direction of the guide rod. Formed, endometrial aspiration biopsy sampler. The method of claim 2,
The rocker,
A rocker body having a locking protrusion formed perpendicular to the insertion direction of the guide rod, and a curved portion formed to be curved in an arc shape from the locking protrusion toward a drawing direction of the guide rod; And
Endometrial suction biopsy sampler comprising a support rib for stationery the locker body to the guide rod so that the locker body is jammed or released from the locking groove. The method of claim 1,
Is mounted on the outer periphery of the guide rod, further comprising a packing member for packing between the guide rod and the sampler body, endometrial suction biopsy sampler. The method of claim 1,
Provided in the sampler body, the endometrial suction biopsy sampler further comprising a guide wire for deforming the shape of the insertion end corresponding to the shape of the uterine lumen. The method of claim 1,
The sampler body comprises a flexible material, endometrial suction biopsy sampler. The method of claim 1,
An endometrial suction biopsy sampler provided in at least one area around the sample recovery hole and further comprising a blade for collecting a sample from the lumen of the uterus. The method of claim 8,
The sample recovery hole is provided in a pair,
The pair of specimen recovery holes are arranged at a certain angle around the insertion end, and a blade provided in one specimen recovery hole and a blade provided in the other specimen recovery hole are respectively formed of a specimen recovery hole on one side and a specimen recovery hole on the other side. Endometrial aspiration biopsy sampler disposed around the periphery located in opposite directions. The method of claim 1,
Endometrial suction biopsy sampler further comprising a plurality of scales displayed at regular intervals along the longitudinal direction of the sampler body on the outer periphery of the sampler body.

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