KR102185269B1 - Apparatus, method, computer-readable storage medium and computer program for personalized tinnitus treatments - Google Patents

Abstract

An apparatus for personalized tinnitus treatment according to various embodiments comprises: a speaker; a first electrode which comprises a discharge port formed to output a first sound stimulus through the speaker to the outside, has a shape that can be mounted on a part of a user′s ear, and can output a current stimulus; and at least one second electrodes for detecting a user′s bio-signal generated in response to the output of the first sound stimulus.

Description

Devices, methods, computer-readable recording media and computer programs for personalized tinnitus treatment {APPARATUS, METHOD, COMPUTER-READABLE STORAGE MEDIUM AND COMPUTER PROGRAM FOR PERSONALIZED TINNITUS TREATMENTS}

The present invention relates to an apparatus, a method, a computer-readable recording medium, and a computer program for personalized tinnitus treatment.

Conventional tinnitus treatment is mainly performed by masking using hearing aids and adaptive rehabilitation training, and there is no standard treatment for substantially reducing tinnitus. In addition, various treatments such as drugs such as betahistine and transcranial magnetic stimulation (TMS) have been proposed in the past, but their effectiveness has not been confirmed.

Recently, studies on the treatment of tinnitus using a neuromodulation technique that enhance brain plasticity by simultaneously applying sound and electrical stimulation have been actively conducted. Bimodal stimulation therapy, which is an invasive method requiring surgery or a non-invasive method that can be treated without surgery, has been proposed. For example, treatments that attempt to treat tinnitus in a patient by electrical stimulation of the vagus nerve and/or the trigeminal nerve simultaneously with sound stimulation have been proposed.

The proposed invasive or non-invasive treatment studies generally apply various stimulating conditions such as duration of treatment, intensity and time of sound/electrical stimulation to all tinnitus patients. According to the results of the study, the duration of the effect of tinnitus treatment differs for each patient, and the treatment may not be effective for some patients. Therefore, a personalized treatment that controls various stimulation conditions based on diagnosis while performing treatment during daily life is required, but the currently proposed tinnitus treatment devices do not include a structure for observing the treatment effect.

In addition, the invasive treatment method has a disadvantage in that a current stimulator must be implanted in the patient's body through surgery in order to directly stimulate the vagus nerve.

In addition, the non-invasive treatment method has the advantage of not performing surgery, but has a disadvantage in that the treatment must be performed for a relatively long time of 30 minutes or more per day in a situation where the patient's movement is restricted. For example, in the case of a non-invasive electric current stimulation method in which an electrode is placed under the tongue to stimulate the trigeminal nerve, the patient must keep holding the electrode, so movement is limited during the treatment period and daily activities are difficult. There are drawbacks.

US registration number US 9265660 (registration date 2016.02.23)

An embodiment of the present invention provides an apparatus, method, and computer-readable recording medium for personalized tinnitus treatment that can objectively monitor (diagnose tinnitus) and adjust stimulation time and intensity based on the change in a patient according to treatment. Computer programs can be provided.

For example, the present invention may diagnose tinnitus based on a response of an EEG according to a sound stimulus to enable personalized tinnitus treatment based on the tinnitus diagnosis.

An embodiment of the present invention may provide an apparatus, a method, a computer-readable recording medium, and a computer program for personalized tinnitus treatment in a non-invasive manner that can simultaneously apply sound and current stimuli.

For example, the present invention may provide a way to non-invasively stimulate a branch of the vagus nerve and/or trigeminal nerve in the ear or near the ear of a patient.

For example, the present invention can provide a personalized tinnitus treatment device in the form of a headset that is familiar to all patients and capable of treating tinnitus in daily life. The personalized tinnitus therapy device in the form of a headset may provide both electric current and sound stimulation at the ear or near the ear, thereby minimizing the patient's movement restrictions.

According to various embodiments, there is provided an apparatus for personalized tinnitus treatment, comprising: a speaker; A first electrode that includes a discharge port formed to output the first sound stimulus through the speaker to the outside, has a shape that can be mounted on a portion of the user's ear, and is capable of outputting a current stimulus; And the output of the first sound stimulus It may include one or more second electrodes for detecting a user's bio-signal generated in response to the response.

According to various embodiments, the device further includes a cable electrically connected to the speaker and the first electrode, wherein the at least one second electrode is positioned on at least a portion of the cable and is electrically connected to the cable. I can.

According to various embodiments, at least a portion of the cable on which the second electrode is located is a portion of an auricular branch of vagus nerve in the ear or a portion of an in-the-ear, ear canal, or a pinna. It may include a predetermined portion to correspond to the portion of the scalp behind the (behind-the-ear).

According to various embodiments, the user's biosignal includes the user's brainwave, and further includes a control unit electrically connected to the cable, and the control unit diagnoses the user's tinnitus based on the detected biosignal. And outputting a second sound stimulus through the speaker and a current stimulus through the first electrode based on the result of the user's tinnitus diagnosis.

According to various embodiments of the present disclosure, the device may include another speaker; A first additional electrode that includes a discharge hole formed to output the first sound stimulus through the other speaker to the outside, has a shape that can be mounted on a portion of the user's ear, and can output a current or voltage stimulus; Another cable electrically connected to the other speaker and the first additional electrode; And one or more second additional electrodes positioned on at least a portion of the other cable and electrically connected to the other cable to detect a user's bio-signal generated in response to the output of the first sound stimulus, the other The cable may be electrically connected to the control unit.

According to various embodiments, the first sound stimulus includes a first stimulus sound including a pulse noise and a first background noise, and a second background sound with a pulse sound and a silent gap. It may include a plurality of included second stimulus sounds.

According to various embodiments, the controller comprises: a first waveform of the user's hearing-producing potential according to the first stimulus sound and a plurality of second waveforms of the user’s hearing-producing potential according to the plurality of second stimulus sounds Is detected, and a plurality of GPI (gap prepulse inhibition) ratios, which is a ratio between the amplitude between poles of the first waveform and the amplitudes between poles of the plurality of second waveforms, may be calculated to diagnose the user's tinnitus.

According to various embodiments of the present disclosure, the control unit may output the second sound stimulus and the first electrode based on a sound stimulation parameter and a current stimulation parameter corresponding to each type of tinnitus stored in advance, and a result of the user's tinnitus diagnosis. The output of the current stimulus can be controlled.

According to various embodiments of the present disclosure, the device further includes an optical sensor, and the control unit, while outputting the second sound stimulus through the speaker and the current stimulus through the first electrode, The user's electrocardiogram (ECG) may be measured through the second electrode, and the user's photoplethysmogram (PPG) may be measured using the optical sensor.

According to various embodiments, the controller, based on the measured ECG and the measured optical volume pulse wave, checks the user's heart rate variability, and determines corresponding stress information for each preset heart rate variability and the checked heart rate variability. Based on the user's stress value can be determined

According to various embodiments, the controller determines the user's heart rate and respiration rate based on the measured electrocardiogram and the measured optical volumetric pulse wave, and when the determined heart rate and respiration rate exceed a preset threshold range, the The output of the second sound stimulus through the speaker and the current stimulus through the first electrode may be controlled to stop or decrease the output.

According to various embodiments of the present disclosure, the controller controls the output of the second sound stimulus and the output of the current stimulus through the first electrode to be terminated based on a designated reference time, and the output of the second sound stimulus and the second 1 After the output of the current stimulus through the electrode is terminated, the user's bio-signal is re-detected through the one or more second electrodes, and the user's tinnitus diagnosis is performed again based on the re-detected bio-signal. , The degree of effectiveness of the tinnitus treatment may be determined by comparing the result of the performed tinnitus diagnosis and the result of the re-performed tinnitus diagnosis.

According to various embodiments, the biosignal may further include an electrocardiogram.

According to various embodiments of the present disclosure, a method for personalized tinnitus treatment using a device, comprising: outputting a first sound stimulus through a speaker of the device; Detecting a user's bio-signal generated in response to an output of the first sound stimulus through a detection electrode of the device; Performing a tinnitus diagnosis of the user based on the EEG included in the detected biometric signal; And outputting a second sound stimulus through the speaker and outputting a current stimulus through at least one current stimulus applying electrode of the device, based on a result of the user's tinnitus diagnosis.

According to various embodiments of the present disclosure, there is provided a computer-readable recording medium storing a computer program, the computer program comprising: outputting a first sound stimulus through a speaker of the device when executed by a processor; Detecting a user's bio-signal generated in response to an output of the first sound stimulus through a detection electrode of the device; Performing a tinnitus diagnosis of the user based on the EEG included in the detected biometric signal; And outputting a second sound stimulus through the speaker and outputting a current stimulus through at least one current stimulus applying electrode of the device based on a result of the user's tinnitus diagnosis. It may contain instructions for.

According to various embodiments of the present disclosure, there is provided a computer program stored in a computer-readable recording medium, the computer program comprising: outputting a first sound stimulus through a speaker of the device when executed by a processor; Detecting a user's bio-signal generated in response to an output of the first sound stimulus through a detection electrode of the device; Performing a tinnitus diagnosis of the user based on the EEG included in the detected biometric signal; And outputting a second sound stimulus through the speaker and outputting a current stimulus through at least one current stimulus applying electrode of the device based on a result of the user's tinnitus diagnosis. It may contain instructions for.

According to various embodiments, there is provided an apparatus for personalized tinnitus treatment, comprising: a speaker; And a discharge port formed to output the first sound stimulus through the speaker to the outside, has a shape that can be mounted on a part of the user's ear, and outputs a current or voltage stimulus, and in response to the output of the first sound stimulus It may include an electrode for detecting the generated bio-signal of the user.

The apparatus, method, computer-readable recording medium, and computer program for personalized tinnitus treatment according to an embodiment of the present invention enable tinnitus diagnosis and treatment to be performed in one device so that the treatment effect can be tracked. It is possible to improve the efficiency of tinnitus treatment by applying personalized stimulation rather than giving the same stimulation to all patients.

For example, according to the present invention, a wearable type of tinnitus treatment device may be manufactured, and a patient in need of tinnitus treatment may be provided with tinnitus treatment for a required time without restriction of place and movement.

An apparatus, method, computer-readable recording medium and computer program for personalized tinnitus treatment according to an embodiment of the present invention, secure the patient's treatment safety by checking the patient's respiratory rate and/or heart rate information, and the patient's stress side. Can make it possible to evaluate the treatment of tinnitus in

1 is a block diagram of an apparatus for personalized tinnitus treatment according to an embodiment of the present invention.
2 and 3 are views for explaining the structure of a device for personalized tinnitus treatment according to an embodiment of the present invention.
4 is a view for explaining the operation of a device for personalized tinnitus treatment according to an embodiment of the present invention.
5 is a view for explaining a stimulation waveform provided for the treatment of tinnitus according to an embodiment of the present invention.
6 is a view for explaining a stimulation waveform provided for the treatment of tinnitus according to an embodiment of the present invention.
7 is a flowchart illustrating an operation and method of an apparatus for treating tinnitus according to an embodiment of the present invention.
8 is a flowchart of an operation for treating tinnitus according to an embodiment of the present invention.
9 is a block diagram of an apparatus for personalized tinnitus treatment according to an embodiment of the present invention.
10 and 11 are views for explaining the structure of a device for personalized tinnitus treatment according to an embodiment of the present invention.

First, the advantages and features of the present invention, and a method of achieving them will become apparent with reference to embodiments to be described later in detail together with the accompanying drawings. Here, the present invention is not limited to the embodiments disclosed below, but may be implemented in a variety of different forms, only the present embodiments are intended to complete the disclosure of the present invention, and are common in the technical field to which the present invention pertains. Since it is provided by way of example in order to allow a person skilled in the art to clearly understand the scope of the invention, the technical scope of the invention should be defined by the claims.

In addition, in the following description of the present invention, if it is determined that a detailed description of known functions or configurations may unnecessarily obscure the subject matter of the present invention, a detailed description thereof will be omitted. In addition, terms to be described later are terms defined in consideration of functions in the present invention, which may vary according to intentions or customs of users and operators. Therefore, the definition should be made based on the technical idea described throughout the specification.

Tinnitus refers to a symptom of hearing sound from the ear in the absence of external auditory stimulation. For the treatment of tinnitus, conventionally, a method of providing stimulation for treatment to all tinnitus patients collectively has been used, not customized tinnitus treatment based on tinnitus diagnosis. Accordingly, there are people who have no effect on treatment, and the duration of the effect also differs from person to person. An embodiment of the present invention provides a tinnitus diagnosis for a patient, provides tinnitus treatment based on tinnitus diagnosis, and provides a tinnitus treatment based on the tinnitus treatment so that the patient is provided with great convenience in the treatment of tinnitus by supplementing the conventional problem. We propose a patient-specific treatment that can control the stimulation time and stimulation intensity for tinnitus treatment by monitoring changes in

As an example of the tinnitus treatment, a method of stimulating the vagus nerve, the trigeminal nerve, and/or the cervical spinal cord simultaneously with sound stimulation may be used. Conventionally, an invasive method through surgery has been used to directly stimulate the vagus nerve, but an embodiment of the present invention proposes a method capable of non-invasive stimulation of a branch of the vagus nerve in the ear. In addition, in the related art, the user must hold the electrode so that the electrode is positioned under the tongue in order to stimulate the trigeminal nerve, but an embodiment of the present invention proposes a method of stimulating the branch of the trigeminal nerve in the ear. The embodiment of the present invention focuses on the fact that it is possible to manufacture an integrated tinnitus treatment device (device) in a very small form when a current stimulus is provided to the ear and sound stimulus is provided together. For example, the tinnitus treatment device in the form of a headset In the case of manufacturing, the user may be provided with stimulation for tinnitus treatment while performing daily life without restriction of movement.

Hereinafter, exemplary embodiments of the present invention will be described in detail with reference to the accompanying drawings.

1 is a block diagram of an apparatus for personalized tinnitus treatment according to an embodiment of the present invention.

Referring to FIG. 1, the device 100 may include a control unit 110, a measurement unit 150, a stimulation unit 130, a memory 170, and/or an optical sensor 390.

The control unit 110 (also referred to as a control device, a control circuit, or a process) includes at least one other component of the connected device 100 (eg, a hardware component (eg, a measurement unit 150), a magnetic pole unit 130, a memory). 170 and/or the optical sensor 190) or a software component (for example, the software 180) may be controlled, and various data processing and operations may be performed.

The stimulation unit 130 may include a first electrode 143, a digital analog converter (DAC) 131 and/or a current stimulation circuit 133. The signal transmitted from the control unit 110 may be transmitted to the first electrode 141 through the DAC 131 and the current stimulation circuit 133. The stimulation unit 130 may include a digital analog converter (DAC) 135, an audio amplifier 137, and/or a speaker 139. The signal transmitted from the controller 110 may be transmitted to the speaker 139 through the DAC 135 and the audio amplifier 137. The current stimulation circuit 133 may generate a current stimulation to be provided to a user through the first electrode 143 under the control of the controller 110. The speaker 139 may output (provide to a user) a sound stimulus under the control of the controller 110.

The measurement unit 150 may include a second electrode 143, an analog front-end 151 and/or an analog digital converter (ADC) 153. The signal detected through the second electrode 141 may be transmitted to the controller 110 through the analog front-end 151 and the ADC 153. The second electrode 143 may be used to detect (measure, confirm) a user's brain waves (reaction of brain waves) under the control of the controller 110. The second electrode 141 may be used to detect an electrocardiogram (ECG) or impedance of a user under the control of the controller 110.

The memory 170 includes various data used by at least one component of the device 100 (eg, the control unit 110, the measurement unit 150, the magnetic pole unit 130 and/or the optical sensor 190), For example, input data or output data for the software 180 (eg, a program) and commands related thereto may be stored. The memory 170 may include a volatile memory or a nonvolatile memory. The software 180 may be a software program for personalized tinnitus treatment according to an embodiment of the present invention.

The optical sensor 390 (also referred to as a PPG (photoplethysmogram) sensor) may detect a user's photoplethysmogram (PPG) signal.

Some of the constituent elements of FIG. 1 may be omitted (not included) or integrated into one entity to perform the same or similar functions performed by the respective constituent elements prior to integration, Other components can be added. For example, the device 100 may not include the optical sensor 390.

2 and 3 are views for explaining the structure of a device for personalized tinnitus treatment according to an embodiment of the present invention.

Referring to FIG. 2, the device 100 may be a headset (or earphone) type device (also referred to as a device) for the treatment of tinnitus that can measure bimodal stimulation and EEG as shown in FIG. 2A. The bimodal stimulation may include sound stimulation and current stimulation.

The device 100 focuses on the fact that a number of branches of the vagus nerve are distributed in the external acoustic meatus 11 as shown in FIG. 2(b), and the inner ear canal 11 It may be implemented as a structure 1400 including a current stimulation applying electrode (first electrode 143) and a reference electrode 144 capable of providing electrical stimulation to the ear canal 11 based on ear innervation). . The first electrode 143 may be referred to as a cathode, and the reference electrode 144 may be referred to as an anode. For example, the device 100 may include a structure 1400 including a first electrode 143 and a reference electrode 144 that may be mounted on a portion of a user's ear. The structure 1400 may have a shape as shown in FIG. 2(b) or 2(c). For example, referring to (b) of FIG. 2, each of the first electrode 143 and the reference electrode 144 included in the structure 1400 is a discharge hole ( 121) may be spaced apart from each other in a direction parallel to the position. 2(c), each of the first electrode 143 and the reference electrode 144 included in the structure 1400 is perpendicular to the position of the discharge port 121 as shown in FIG. 2(c). It can be located spaced apart from each other in the direction. In addition, the device 100 may further include one or more measuring electrodes (second electrodes 145) positioned on at least a portion of the cable 123 connected to a portion of the first electrode 143. When the user wears the device 100, the first electrode 143 may be positioned at a portion corresponding to the auricular branch of vagus nerve 13. The structure 1400 may include a discharge port 121 (also referred to as a hole) formed to output sound stimuli through the speaker 159 to the outside (formed to be output to the user's ear), and to apply a current stimulus. have. The one or more measurement electrodes may be positioned on a portion of an ear in which a branch of a person's vagus nerve or trigeminal nerve is distributed, or at least a portion of the cable 123 around the ear. For example, the one or more measurement electrodes may include a second electrode 145 and a third electrode 147 and a fourth electrode 149 that have the same function as the second electrode 145 and the third electrode 145. The electrode 147 and the fourth electrode 149 may be respectively positioned on a part of the cable 123 corresponding to the innervation of the external ear canal in which a number of branches of a person's vagus nerve or trigeminal nerve are distributed. For example, when the user wears the device 100, the third electrode 147 and the fourth electrode 149 may be located at a portion corresponding to the auticulotemporal nerve 15. .

The shape of the cable 123 is changed according to an external force, and the shape of the cable 123 is changed according to an element or an external force that can maintain the changed shape even when the external force is removed. It may be an elastic element that can return to its original shape.

Meanwhile, the shape of the device 100 as shown in FIG. 2A is an example, and may be changed and implemented (manufactured) into various shapes that can be attached to the user's ear. For example, referring to FIG. 3, the apparatus 100 for treating tinnitus may be in a form in which one or more electrodes are positioned so as to stimulate electric current in a concha. The device 100 may be implemented based on the structure of the user's pinna as shown in FIG. 3, and the device 100 includes a two-channel electrode, for example, a first electrode capable of providing current stimulation to the user. An electrode 143 and a fifth electrode 146 may be included. The first electrode 143 and the fifth electrode 146 may be referred to as a cathode. As an electrode that provides current stimulation, the first electrode 143 and the fifth electrode 146 can be changed according to the stimulation effect. In addition, the device 100 may include a reference electrode 144 for current stimulation and measurement of a user's biological signal. During current stimulation, the reference electrode 144 may be referred to as an anode. For example, when the user wears the device 100, the first electrode 143 and the fifth electrode 146 are in a portion (aVNS) corresponding to the auricular branch of vagus nerve. Can be located.

In addition, the structure 1400 including the first electrode 143 and the reference electrode 142 as shown in (b) and (c) of FIG. 2 described above is for example, the first electrode 143 and the reference electrode The 142 may be disposed in various positions on the structure 1400.

4 is a view for explaining the operation of a device for personalized tinnitus treatment according to an embodiment of the present invention.

Referring to FIG. 4, under the control of the controller 110, a gap-prepulse inhibition 1001 previously stored in the memory 170 or generated by the controller 110 is transmitted through the speaker 159. In this case, an auditory evoked potential of the user may be measured 1003 through the at least one electrode 145. The control unit 110 may diagnose the user's tinnitus (determining whether or not tinnitus, the degree of tinnitus (also referred to as the size of tinnitus), and the tinnitus frequency) based on the measured EEG response.

According to an embodiment, the control unit 110 provides a vagus nerve stimulation 1005 through the first electrode 143 and a sound stimulation 1007 through the speaker 159 based on the result of the tinnitus diagnosis. (neuromodulation) allows the user to treat tinnitus. For example, the controller 110 may enable personalized tinnitus treatment by adjusting treatment time and stimulation intensity based on the degree of tinnitus of the user.

According to an embodiment, the controller 110 may execute the software 180 to generate a pre-pulse spacing sound stimulus and output it through the speaker 159. For example, the pre-pulse spacing method sound stimulus includes a first stimulus sound including a background noise and a pluse noise, and a second stimulus sound including a background sound and a pulse sound having a silent gap. It may include a stimulus sound. The background sound represents a sound sustained for a predetermined time at a predetermined frequency and a predetermined amplitude, and the pulsed sound represents a sound having a greater intensity than the background sound for a period shorter than a predetermined time during which the background sound continues.

According to an embodiment, the control unit 110 may measure a response of a user's brain waves according to the pre-pulse interval method sound stimulus using the one or more measuring electrodes 145. For example, the controller 110 includes a first waveform of a user's auditory evoked potential (AEP) according to the first stimulus sound, and a second waveform of the user's auditory evoked potential according to the second stimulus sound Can be measured. The auditory-induced potential is a potential that occurs in the auditory pathway from the cochlea of the inner ear to the auditory cortex of the cerebrum after the occurrence of sound stimulation. It is distinguished. Among them, the electric potential that occurs in the brainstem within about 10 ms after the occurrence of the sound stimulus is called the auditory brainstem response, and in the auditory brainstem response, generally seven positive poles ranging from I to VII are appear. In addition, the response that occurs in the thalamo-cortical pathway between the brain stem and the cerebral auditory cortex can be referred to as the auditory middle-latency response and is named N0, P0, Na, Pa, Nb, and Pb. Pole points appear. Finally, the response that occurs in the cerebral auditory cortex can be referred to as the auditory late response, and typically includes poles called P1, N1, P2, and N2. The amplitude of the poles referred to in the exemplary embodiment of the present invention may mean the amplitude of one or more poles among a plurality of poles appearing in the hearing inducing potential, and is not limited to any pole. In addition, the amplitude may be the amplitude of the pole itself (baseline-to-peak) and may be the amplitude between the poles (peak-to-peak).

According to an embodiment, the control unit 110 determines whether the user is tinnitus by calculating a gap prepulse inhibition ratio (GPI), which is a ratio between the amplitude between poles of the first waveform and the amplitude between poles of the second waveform. , Diagnosis). For example, in the case of users with tinnitus symptoms, the GPI may be close to 1 because the difference between the hearing-induced potential according to the first and second stimulation sounds is small, and general users without tinnitus symptoms (general users group) The GPI of may appear smaller than that of users with tinnitus symptoms. For example, the control unit 110 receives the GPI, measured from a group of users with tinnitus symptoms and a group of general users without symptoms of tinnitus, and based on the reference GPI values previously stored in the memory 170, You can decide whether the user has a tinnitus.

According to an embodiment, the control unit 110 receives a plurality of GPI ratios determined by a user, and changes the amplitude or frequency of the background sound for the tinnitus user group and the general user group, based on the measured amplitude and GPI. Based on the derived and stored classification models, the degree of tinnitus and the tinnitus frequency of the user may be determined.

According to an embodiment, based on the user's tinnitus diagnosis (eg, tinnitus degree and tinnitus frequency) according to the above-described operations, the control unit 110 provides a treatment method (treatment time and stimulation (sound stimulation and / Or current stimulation) intensity, etc.) can be determined (set, check). For example, the memory 170 corresponds to a treatment method (treatment time and/or stimulation for treatment (sound stimulation and/or current stimulation) intensity) according to a plurality of tinnitus diagnosis types (tinnitus degree and/or tinnitus frequency) May be stored, and a treatment method for the user's tinnitus treatment may be determined according to the user's tinnitus diagnosis based on a treatment method corresponding to each of a plurality of tinnitus diagnosis types stored in the memory 170.

According to an embodiment, the control unit 110 may allow the user to receive tinnitus treatment based on the determined treatment method (treatment time and/or intensity of stimulation (sound stimulation and/or current stimulation) for treatment). . For example, the control unit 110 may provide sound stimulation through the speaker 159 and/or current stimulation through the first electrode 143.

According to an embodiment, according to the control of the controller 110, the biosignal of the user is detected through one or more electrodes 141 or a separate optical sensor 190, for example, an electrocardiogram (ECG), Impedance and/or photoplethysmogram (PPG) may be measured, and information on the user's respiration and heart rate may be determined (extracted) based on the biological signal.

For example, the at least one electrode 141 included in the measurement unit 150 detects a user's biosignal under the control of the control unit 110 (eg, an electrocardiogram (ECG) or an impedance measurement) )can do. For example, the optical sensor 190 may detect a user's bio-signal under the control of the controller 110, for example, measure a photoplethysmogram (PPG).

According to an embodiment, the controller 110 checks (extracts) the user's heart rate and/or respiration rate based on the biosignal detected through the measurement unit 150 and/or the optical sensor 190. can do.

For example, the controller 110 may extract a peak of the biosignal after filtering the biosignal of about 1 to 30Hz, and determine the user's heart rate based on the extracted peak. I can. For example, the controller 110 may detect a frequency of the biosignal and/or extract a peak after filtering the biosignal of about 0.1 to 2Hz, and the detected frequency and / Or the number of breaths of the user may be determined based on the extracted peak. The operation of determining the user's heart rate and/or respiration rate is already known in the art and a detailed description thereof will be omitted.

According to an embodiment, the control unit 110 may control one or more components of the device 100 to allow the user to receive tinnitus treatment. During the tinnitus treatment, the measurement unit 150 and/or the light The user's heart rate and/or respiration rate may be determined using the sensor 190. The control unit 110, in terms of the safety of the tinnitus treatment, when the user breathes excessively or the user's heart rate is rapidly changed (for example, the user's heart rate is changed to bradycardia), the tinnitus treatment Can be stopped. The control unit 110 may perform a quantitative evaluation of the user's stress for the tinnitus treatment by using heart rate variability (HRV), which is one of the chronic stress indicators.

For example, the control unit 110, during the output of the current stimulation through one or more electrodes 141 of the stimulation unit 150 and/or the sound stimulation through the speaker 159, the measurement unit ( 150) and/or the optical sensor 190 may detect the user's biosignal, and the user's heart rate and/or respiration rate may be determined based on the detected biosignal.

For example, the controller 110 checks whether the determined heart rate and/or respiration rate is out of a preset reference range (eg, a reference heart rate range and/or a reference respiration rate range), and the determined heart rate and/or respiration rate If it is out of the preset reference range, the output of the current stimulus through the one or more electrodes 141 of the stimulation unit 150 and/or the output of the sound stimulus through the speaker 159 may be stopped.

For example, the controller 110 may check the user's heart rate variability based on the detected bio-signals, for example, ECG and PPG, and the user receives tinnitus treatment based on the confirmed heart rate variability. During the stress can be quantitatively evaluated. For example, the control unit 110 may quantify and output the stress based on a result of comparing the identified heart rate variability and the reference heart rate variability (also referred to as a threshold value).

5 is a view for explaining a stimulation waveform provided for the treatment of tinnitus according to an embodiment of the present invention.

Referring to FIG. 5A, a device for treating tinnitus (for example, the device 100 or the controller 110 of the device 100) is based on a preset condition and/or a result of a previous tinnitus treatment, It is possible to determine (set, change) parameters of sound stimulation to be provided for tinnitus treatment. The parameters of the sound stimulus include the type of sound stimulus (tone, tone combination, white noise), the size of the sound stimulus (Amp1), and/or the output time of the sound stimulus (eg, one output time) (d1). can do. For example, the device for the treatment of tinnitus determines the type of the sound stimulus as white noise, the magnitude of the sound stimulus (Amp1) is determined as 90 dB SPL, and the output time of the sound stimulus once (d1) Can be determined from 20 to 500 ms.

Referring to FIG. 5B, the device for tinnitus treatment determines (set, change) parameters of current stimulation to be provided for tinnitus treatment based on a preset condition and/or a result of a previous tinnitus treatment. can do. The parameters of the current stimulation include the size of the current stimulation (Amp2), the width of the current stimulation (d2), the distance provided for each current stimulation (d3), and/or the output time of the current stimulation (e.g., one output time ) (d4) may be included. For example, the device for the treatment of tinnitus determines the size of the current stimulation to be less than 5 mA, the width d2 of the current stimulation to be 5 to 200us, and the provision distance d3 for each of the current stimulations. It may be determined as 2 to 50 ms, and one output time d4 of the current stimulation may be determined as 20 to 500 ms.

According to an embodiment, the sound stimulation and the current stimulation may be composed of a sound and current stimulation pair, and the device for treating tinnitus is based on a preset condition and/or a result of a previous tinnitus treatment. , It is possible to determine (set, change) an interval between the sound and current stimulation pairs and a total stimulation time.

For example, the apparatus for treating tinnitus may determine an interval between the sound and current stimulation pairs to be 100 ms or less, and an initial value of the total stimulation time to be 30 minutes or more. For example, the device for treating tinnitus may determine the timing of the output of sound and current stimuli in sound and current stimulus pairs.

The stimulation waveform provided for the tinnitus treatment of FIG. 5 described above may be variously changed as shown in FIG. 6 to be described later as an example.

6 is a view for explaining a stimulation waveform provided for the treatment of tinnitus according to an embodiment of the present invention.

Referring to FIG. 6A, the parameters of the sound stimulus to be provided for tinnitus treatment may include an output waveform of the sound stimulus in the form of a sine wave including an amplitude of A1 and a period of F1. In addition, the parameters of the sound stimulus to be provided for the treatment of tinnitus include a preset output time (for example, one output time) (T1, T2) of the output waveform of the sound stimulus and the output times of the output waveforms of the sound stimulus (T1 , T2) may include a preset silence interval T2.

Referring to (b) of FIG. 6, the parameter of the current stimulation for tinnitus treatment includes an output delay time (T4) for outputting the current stimulation after a preset time elapses after the sound stimulation is output. I can. In addition, the parameters of the current stimulation for the tinnitus treatment include a first waveform 61 including a square wave having one period P1 and a pause time P2 not outputting the current stimulation, and the first waveform ( 61) of the output time (T5).

7 is a flowchart illustrating an operation and method of an apparatus for treating tinnitus according to an embodiment of the present invention.

Referring to FIG. 7, in operation 701, a device for treating tinnitus (eg, the device 100 or the controller 110 of the device 100) may output a sound stimulus.

According to an embodiment, the device may output a pre-pulse spacing sound stimulus that is preset or generated according to the above-described embodiment through a speaker (eg, speaker 159).

In operation 703, the device may detect the user's EEG.

According to an embodiment, the device may detect a user's EEG through one or more electrodes (eg, electrode 145, electrode 147, electrode 149). For example, the device may detect the user's brain waves after or during the output of the sound stimulus.

In operation 705, the device may diagnose (determine) the degree and frequency of tinnitus of the user.

According to an embodiment, the device may diagnose a user's tinnitus degree and tinnitus frequency based on the detected brain waves.

For example, the device may extract preset features from the detected brain waves, and diagnose the degree of tinnitus and the tinnitus frequency of the user based on the extracted features. For example, the preset features may include N1_amp (gap), Delta_rel_power, N1P2_ratio, Theta_rel_power, N1P2_auc (gap), Alpha_rel_power, Total_auc (gap), Beta_rel_power, Total_auc (nogap), and/or Gamma_rel_power. Since the user's tinnitus degree and the operation of diagnosing the tinnitus frequency have been described above, detailed descriptions are omitted.

In operation 707, the device may output a stimulus for treating tinnitus of the user.

According to an embodiment, the device outputs sound stimulation through the speaker and current stimulation through one or more electrodes (eg, electrode 141 and electrode 143) based on the diagnosis of the tinnitus degree and tinnitus frequency. can do. Since the output operation of the sound and current stimulation has been described above, detailed descriptions are omitted.

In operation 709, the device may check whether the tinnitus treatment time exceeds a preset threshold time (N).

If the tinnitus treatment time exceeds a preset threshold time, operation 717 may be performed. Otherwise, operation 711 may be continuously performed.

In operation 711, the device may check the user's respiratory rate and heart rate.

According to an embodiment, the device may measure an electrocardiogram and a photovoltaic pulse wave, and check the user's respiration rate and heart rate based on the measurement.

In operation 713, the device may check whether a result value according to the check exceeds a preset normal range (also referred to as a threshold range).

If the result value according to the check is out of a preset normal range, operation 715 may be performed. Otherwise, operation 707 may be continued.

In operation 715, the device may output information indicating that a result value according to the check is out of a normal range.

According to an embodiment, the device transmits the information to the display device and/or outputs the information as a voice through a speaker of the device so that the information is visually output to a display device communicating with the device. I can.

After operation 715, the operation of the present embodiment may be terminated.

In operation 717, the device may detect the user's EEG.

According to an embodiment, the device may detect a user's EEG through one or more electrodes (eg, electrode 141 and electrode 145).

In operation 719, the device may diagnose the degree and frequency of tinnitus of the user.

According to an embodiment, the device may diagnose a user's tinnitus degree and tinnitus frequency based on the detected brain waves.

In operation 721, the device may determine the effect of the tinnitus treatment.

According to an embodiment, the device may determine the effect of the tinnitus treatment based on the diagnosis of the tinnitus degree and tinnitus frequency. For example, the device may determine the effect of the tinnitus treatment by comparing the degree and tinnitus frequency diagnosed in operation 705 with the degree and tinnitus frequency diagnosed in operation 713. For example, the device may digitize and output the effect of the tinnitus treatment, and determine the effect of the tinnitus treatment based on a value according to the digitization.

In the embodiment of FIG. 7 described above, the device additionally outputs visual information corresponding to the effect of the tinnitus treatment through a display unit (not shown) of the device and/or audio information corresponding to the effect of the tinnitus treatment. Is output through the speaker of the device, so that the user can confirm.

8 is a flowchart of an operation for treating tinnitus according to an embodiment of the present invention.

Referring to FIG. 8, in operation 801, a device for treating tinnitus (for example, the device 100 or the controller 110 of the device 100) provides a first sound through a speaker (for example, the speaker 159) of the device. Can output stimulation.

According to an embodiment, the device includes the speaker and a discharge port formed to output sound stimuli through the speaker to the outside, and a first electrode (eg, a first electrode) that can be mounted on a portion of a user's ear. (143)), a cable (for example, a cable 123) electrically connected to the speaker and the first electrode, and at least one second electrode (for example, one or more second electrodes located on at least a portion of the cable and electrically connected to the cable) One or more second electrodes 145) may be included. For example, at least a portion of the cable on which the second electrode is located is a part of the auricular branch of vagus nerve in the ear or in the in-the-ear (ear canal) part or behind the auricle. (behind-the-ear) It may include a predetermined portion to correspond to the scalp portion.

According to an embodiment, the first sound stimulus includes a first stimulus sound including a pulse noise and a first background noise, and a second background sound with a pulse sound and a silent gap. It may include a plurality of included second stimulus sounds.

In operation 803, the device may detect an EEG of a user through one or more second electrodes of the device, based on the output of the first sound stimulus.

According to an embodiment, the device may generate a first waveform of the user's hearing-induced potential according to the first stimulus sound and a plurality of second waveforms of the user's hearing-induced potential according to the plurality of second stimulus sounds. Can be detected.

In operation 805, the device may diagnose tinnitus of the user based on the detected EEG.

According to an embodiment, the device performs tinnitus diagnosis of the user by calculating a plurality of GPI (gap prepulse inhibition) ratios, which is a ratio between the amplitude between poles of the first waveform and the amplitudes between poles of the plurality of second waveforms. can do.

In operation 807, the device may output a second sound stimulus through the speaker and a current stimulus through a first electrode of the device, based on a result of the user's tinnitus diagnosis.

According to an embodiment, the device outputs the second sound stimulus and corresponds to the user's tinnitus diagnosis based on the pre-stored sound stimulation parameter and current stimulation parameter corresponding to each tinnitus type, and a result of the user's tinnitus diagnosis. The current stimulation can be output.

In addition to the embodiment of FIG. 8 described above, the device may further include an optical sensor (eg, the optical sensor 190). In addition, the device, while outputting the second sound stimulus through the speaker and the current stimulus through the first electrode, the user's electrocardiogram (ECG) through the at least one second electrode. It is measured, and the user's photoplethysmogram (PPG) may be measured using the optical sensor. In addition, the device, based on the measured ECG and the measured optical volume pulse wave, checks the user's heart rate variability, and corresponds to the confirmed heart rate variability based on stress information corresponding to each preset heart rate variability The stress of the user can be determined. For example, the device may quantify and output the stress. In addition, the device determines the user's heart rate and respiration rate based on the measured electrocardiogram and the measured optical volumetric pulse wave, and when the determined heart rate and respiration rate exceed a preset threshold range, the speaker The output of the second sound stimulus and the current stimulus through the first electrode may be controlled to stop or decrease the output.

In addition to the above-described embodiment, the device controls the output of the second sound stimulus and the output of the current stimulus to end based on a designated reference time, and after the output is terminated, the at least one second electrode The effect of tinnitus treatment by re-detecting the user's EEG, re-performing the user's tinnitus diagnosis based on the re-detected EEG, and comparing the result of the performed tinnitus diagnosis and the result of the re-performed tinnitus diagnosis Can be determined.

Meanwhile, in the above-described embodiment, it has been described that the first electrode (for example, the first electrode 143) and the second electrode (for example, one or more second electrodes 145) are separated from each other. 100) includes only one electrode, the one electrode outputs a current or voltage stimulus and detects a user's bio-signal For this operation, the device is configured as shown in FIG. 9 to be described later. It may include.

9 is a block diagram of an apparatus for personalized tinnitus treatment according to an embodiment of the present invention.

Referring to FIG. 9, the device 100 includes the components of FIG. 1, for example, a controller 110, a digital analog converter (DAC) 131, a current stimulation circuit 133, and a DAC ( 135), an audio amplifier 137, a speaker 139, an optical sensor 190, an analog front-end 151, and/or an analog digital converter (ADC) 153, Each component may perform an operation corresponding to the component of FIG. 1. The device 100 may include one electrode 141 instead of the first electrode 143 and the second electrode 145 of FIG. 1. The device 100 may further include a switch 901. The switch 901 is connected to the analog front-end 151 so that the electrode 141 can detect a user's bio-signal (eg, electrocardiogram or impedance) based on the control of the controller 110 Alternatively, the electrode 151 may be switched to be connected to the current stimulation circuit 153 in order to output a current or voltage stimulation.

Accordingly, according to an embodiment of the present invention, the device 100 includes a speaker (eg, a speaker 139), an electrode, and/or a cable (eg, a cable (eg, a cable) electrically connected to the speaker and the electrode). 123)). For example, the one electrode includes an outlet formed to output a first sound stimulus through a speaker of the device to the outside, has a shape that can be mounted on a part of the user's ear, and outputs a current or voltage stimulus. , It is possible to detect a user's biosignal generated in response to the output of the first sound stimulus.

Referring to FIG. 2, the one electrode in the embodiment of FIG. 9 described above may be the first electrode 143 or the second electrode 145 in FIG. 2. Comparing the first electrode 143 and the second electrode 145, the second electrode 145 may be less effective than the first electrode 143 in providing current or voltage stimulation to a user. However, the second electrode 145 may also provide current or voltage stimulation to the user. In detecting the user's biosignal, the first electrode 143 may be less effective than the second electrode 145, but the first electrode 143 may also detect the user's biosignal. Accordingly, when considering the therapeutic aspect of the user's tinnitus, the device 100 may include the first electrode 143 as the single electrode.

10 and 11 are views for explaining the structure of a device for personalized tinnitus treatment according to an embodiment of the present invention.

Referring to FIGS. 10 and 11, a yangyi type device 1000 for personalized tinnitus treatment includes an electrode (eg, a first electrode 143) capable of outputting a current or voltage stimulus and a user's biosignal. Two devices including one or more second electrodes (for example, one or more second electrodes 145) capable of detecting a signal may be included to be worn on the right ear and the left ear of the user, respectively. Accordingly, it is possible to measure EEG and electrocardiogram including a user's hearing-induced response by a combination of the stimulating electrode and the left and right electrodes in a bilateral form.

Referring to FIG. 10, the device 1000 may be implemented in a yang type. For example, as shown in FIG. 10, the device 1000 may be implemented so that the user 1001 can wear it on both ears of the user 1001. Accordingly, the device 1000 may include a cable 1230, a first device 100-1 and a second device 100-2.

The first device 100-1 includes a first structure 1400-1 including a 1-1 electrode 143-1 and a first reference electrode (not shown), and the 1-1 electrode 143 -1) may include a first cable 123-1 connected to a portion of the first cable 123-1 and one or more second-1 electrodes 145-1 positioned at least a portion of the first cable 123-1. The one or more 2-1 electrodes 145-1 may include a 3-1 electrode 147-1, a 4-1 electrode 149-1, and a fourth reference electrode 1113.

The second device 100-2 includes a second structure 1400-2 including a 1-2th electrode 143-2 and a second reference electrode (not shown), and the 1-2nd electrode 143 It may include a second cable 123-2 connected to a portion of -2) and one or more second-2 electrodes 145-2 positioned on at least a portion of the second cable 123-2. The one or more 2-2 electrodes 145-2 may include a 3-2 electrode 147-2, a 4-2 electrode 149-2, and a third reference electrode 1111.

The 1-1 electrode 143-1 and the 1-2 electrode 143-2 correspond to the first electrode 143 of FIG. 2, respectively, and the first reference electrode and the second reference electrode are Each corresponds to the reference electrode 144 of FIG. 2, and the first structure 1401-1 and the second structure 1400-2 may correspond to the structure 1400 of FIG. 2, respectively. Each of the first cable 123-1 and the second cable 123-2 may correspond to the cable 123 of FIG. 2. The one or more 2-1 electrodes 145-1 and the one or more 2-2 electrodes 145-2 may correspond to the one or more second electrodes 145 of FIG. 2. The 3-1 electrode 147-1 and the 3-2 electrode 147-2 may correspond to the third electrode 147 of FIG. 2. The 4-1 electrode 149-1 and the 4-2 electrode 149-2 may correspond to the fourth electrode 149 of FIG. 2.

The cable 1230 may be electrically connected to the first cable 123-1 of the first device 100-1, and the second cable 123-2 of the second device 100-2 and Can be electrically connected.

Meanwhile, a separation distance between the 3-1 electrode 147-1 and the 4-1 electrode 149-1, and the 3-2 electrode 147-2 and the 4-2 electrode 149 -2) Keeping the separation distance as far as possible may be more efficient for measuring bio-signals.

Referring to FIG. 11, detailed configurations for measuring a user's biosignal included in the yangyi type device 1000 include a first measurement unit 1100, a second measurement unit 1200, and an electrocardiogram acquisition unit ( 1300), the 3-1 electrode 147-1, the 4-1 electrode 149-1, the 3-2 electrode 147-2, the 4-2 electrode 149-2, the third reference An electrode 1111 and a fourth reference electrode 1113 may be included.

The 3-1 electrode 147-1, the 4-1 electrode 149-1, and the third reference electrode 1111 may be used to measure a biosignal of the right ear. The 3-2 electrode 147-2, the 4-2 electrode 149-2, and the fourth reference electrode 1113 may be used to measure a biosignal of the left ear.

The first measurement unit 1100 is a component for measuring a biosignal of the right ear, and may measure a potential difference between the 3-1 electrode 147-1 and the 4-1 electrode 149-1, The output signal may be extracted and output from the measured potential difference value. The first measurement unit 1100 may include a signal processing unit 523 for extracting a biosignal of the right ear from a potential difference between the 3-1 electrode 147-1 and the 4-1 electrode 149-1. have.

The second measuring unit 1200 is configured for measuring a biosignal of the left ear, and may measure a potential difference between the 3-2 electrode 147-2 and the 4-2 electrode 149-2, The output signal may be extracted and output from the measured potential difference value. The second measuring unit 1200 may include a signal processing unit 524 for extracting a biosignal of the right ear from a potential difference between the 3-2 electrode 147-2 and the 4-2 electrode 149-2. have.

Meanwhile, the device 1000 includes a switch 1115, a third reference electrode 1111, and a fourth reference electrode 1113, and according to a switching operation of the switch 1115, the biosignal of the right ear is measured. During the time, it may be connected to the third reference electrode 1111, and when the biosignal of the left ear is measured, the fourth reference electrode 1113 may be connected.

In addition, in order to acquire the user's electrocardiogram, the electrocardiogram acquisition unit 1300 may measure a potential difference between the 3-1 electrode 147-1 and the 3-2 electrode 147-2, and the The measured potential difference value may be output as an ECG output signal. In the above-described embodiment of FIG. 11, it has been described that the third reference electrode 1111 or the fourth reference electrode 1113 are connected to the device 1000 according to the switching operation of the switch 1115. In this configuration, it is possible to individually measure a biosignal, which is an audible response of one ear of the user. However, according to another embodiment, the third reference electrode 1111 or the fourth reference electrode 1113 is implemented as one reference electrode, and the switch 1115 is excluded, so that the hearing-induced reaction of both ears is a living body. It is also possible to measure signals simultaneously.

Various embodiments of the present document include instructions stored in a machine-readable storage media (eg, memory 215 (internal memory or external memory)) that can be read by a machine (eg, a computer). It can be implemented in software (eg, a program). The device is a device capable of calling a stored command from a storage medium and operating according to the called command, and may include an electronic device (eg, the electronic device 200) according to the disclosed embodiments. When the command is executed by a processor (for example, the processor 201), the processor may perform a function corresponding to the command directly or by using other components under the control of the processor. Instructions may include code generated or executed by a compiler or interpreter. A storage medium that can be read by a device may be provided in the form of a non-transitory storage medium. Here,'non-transient' means that the storage medium does not contain a signal and is tangible, but does not distinguish between semi-permanent or temporary storage of data in the storage medium.

According to an example, the method according to various embodiments disclosed in the present document may be provided by being included in a computer program product.

The above description is merely illustrative of the technical idea of the present invention, and those of ordinary skill in the art to which the present invention pertains, various substitutions, modifications, and changes, etc., within the scope not departing from the essential characteristics of the present invention. It will be easy to see that this is possible. That is, the embodiments disclosed in the present invention are not intended to limit the technical idea of the present invention, but to explain the technical idea, and the scope of the technical idea of the present invention is not limited by these embodiments.

Accordingly, the scope of protection of the present invention should be interpreted by the claims to be described later, and all technical thoughts within the scope equivalent thereto should be interpreted as being included in the scope of the present invention.

The present invention can be used in the diagnosis and treatment of tinnitus in the medical field.

100: device 110: control unit
131: DAC 133: current stimulation circuit
135: DAC 137: audio amplifier
139: speaker 143: first electrode
145: second electrode 150: measuring unit
151: Analog Front-End 153: ADC
170: memory 180: software
190: light sensor

Claims (17)

In the device for personalized tinnitus treatment,
speaker;
A first electrode that includes a discharge port formed to output a first sound stimulus through the speaker to the outside, has a shape that can be mounted on a portion of a user's ear, and can output a current or voltage stimulus; And
At least one second electrode for detecting a user's bio-signal generated in response to the output of the first sound stimulus, and a control unit for controlling the first electrode and the second electrode,
The control unit,
Performing tinnitus diagnosis for the user based on the detected biometric signal,
Control to output a second sound stimulus through the speaker and a current stimulus through the first electrode based on the result of the tinnitus diagnosis for the user,
Personalized tinnitus that controls the output of the second sound stimulus and the output of the current stimulus through the first electrode based on the pre-stored sound stimulus parameter and current stimulus parameter for each tinnitus type and the result of the user's tinnitus diagnosis Device for treatment.
The method of claim 1,
Further comprising a cable electrically connected to the speaker and the first electrode,
The one or more second electrodes are positioned on at least a portion of the cable and are electrically connected to the cable, and the control unit is electrically connected to the cable,
A device for personalized tinnitus treatment. The method of claim 2, wherein at least a portion of the cable on which the one or more second electrodes are located,
Including a predetermined portion to correspond to the auricular branch of the vagus nerve portion in the ear or the in-the-ear (ear canal) portion or the portion of the scalp behind the auricle (behind-the-ear) A device for personalized tinnitus treatment. The method of claim 1,
The device for personalized tinnitus treatment, wherein the user's bio-signal includes the user's brain waves.
The method of claim 2,
Different speakers;
A first additional electrode that includes a discharge hole formed to output the first sound stimulus through the other speaker to the outside, has a shape that can be mounted on a portion of the user's ear, and can output a current or voltage stimulus;
Another cable electrically connected to the other speaker and the first additional electrode; And
One or more second additional electrodes positioned on at least a portion of the other cable and electrically connected to the other cable to detect a user's bio-signal generated in response to an output of the first sound stimulus,
The other cable is electrically connected to the control unit, a device for personalized tinnitus treatment. The method of claim 1, wherein the first sound stimulus,
Personalization including a plurality of second stimulus sounds including a first stimulus sound including pulse noise and a first background noise, and a second background sound with a pulse sound and a silent gap Device for the treatment of tinnitus. The method of claim 6, wherein the control unit,
Detecting a first waveform of the user's hearing-induced potential according to the first stimulus sound and a plurality of second waveforms of the user's hearing-induced potential according to the plurality of second stimulus sounds,
A device for personalized tinnitus treatment for performing tinnitus diagnosis of the user by calculating a plurality of GPI (gap prepulse inhibition) ratios, which is a ratio between the pole-to-pole amplitude of the first waveform and the plurality of second waveforms. In the device for personalized tinnitus treatment,
speaker;
A first electrode that includes a discharge port formed to output a first sound stimulus through the speaker to the outside, has a shape that can be mounted on a portion of a user's ear, and can output a current or voltage stimulus; And
And one or more second electrodes for detecting a user's bio-signal generated in response to the output of the first sound stimulus,
The biological signal is a device for personalized tinnitus treatment including an electrocardiogram. In the device for personalized tinnitus treatment,
speaker;
A first electrode that includes a discharge port formed to output a first sound stimulus through the speaker to the outside, has a shape that can be mounted on a portion of a user's ear, and can output a current or voltage stimulus;
At least one second electrode for detecting a user's bio-signal generated in response to the output of the first sound stimulus, and a controller for controlling the first electrode and the second electrode; And a light sensor,
The control unit,
Based on the detected bio-signal, the user's tinnitus is diagnosed, and based on the result of the user's tinnitus diagnosis, outputting a second sound stimulus through the speaker and a current stimulus through the first electrode Control,
While outputting the second sound stimulus through the speaker and the current stimulus through the first electrode, the user's electrocardiogram (ECG) is measured through the at least one second electrode, and the optical sensor A device for personalized tinnitus treatment that measures the user's photoplethysmogram (PPG) by using. The method of claim 9, wherein the control unit,
Checking the user's heart rate variability based on the measured electrocardiogram and the measured optical volume pulse wave, and determining the user's stress value based on the corresponding stress information for each preset heart rate variability and the confirmed heart rate variability Device for personalized tinnitus treatment The method of claim 9, wherein the control unit,
The user's heart rate and respiration rate are determined based on the measured electrocardiogram and the measured optical volumetric pulse wave, and when the determined heart rate and respiration rate exceed a preset threshold range, output of the second sound stimulus through the speaker And controlling the current stimulation through the first electrode to stop or reduce the output. In the device for personalized tinnitus treatment,
speaker;
A first electrode that includes a discharge port formed to output a first sound stimulus through the speaker to the outside, has a shape that can be mounted on a portion of a user's ear, and can output a current or voltage stimulus; And
At least one second electrode for detecting a user's bio-signal generated in response to the output of the first sound stimulus, and a control unit for controlling the first electrode and the second electrode,
The control unit,
Based on the detected bio-signal, tinnitus diagnosis is performed for the user, and output of a second sound stimulus through the speaker and current stimulus through the first electrode are performed based on the result of the tinnitus diagnosis for the user. Control to output,
Based on a designated reference time, the output of the second sound stimulus and the output of the current stimulus through the first electrode are controlled to be terminated, and the output of the second sound stimulus and the output of the current stimulus through the first electrode are terminated. After that, the biosignal of the user is re-detected through the at least one second electrode,
Based on the re-detected bio-signal, tinnitus diagnosis is performed again for the user, and the result of the performed tinnitus diagnosis and the result of the re-performed tinnitus diagnosis are compared to determine the degree of effectiveness of the tinnitus treatment Device for the treatment of tinnitus. The method of claim 12,
The bio-signal further comprises an electrocardiogram. Device for personalized tinnitus treatment. In the method for personalized tinnitus treatment using a device,
Outputting a first sound stimulus through a speaker of the device;
Detecting a user's bio-signal generated in response to an output of the first sound stimulus through a detection electrode of the device;
Performing a tinnitus diagnosis for the user based on the EEG included in the detected biological signal; And
And outputting a second sound stimulus through the speaker and outputting a current stimulus through at least one current stimulus applying electrode of the device based on a result of the tinnitus diagnosis for the user,
The bio-signal further includes an electrocardiogram. As a computer-readable recording medium storing a computer program,
The computer program, when executed by a processor,
Outputting a first sound stimulus through a speaker of the device;
Detecting a user's bio-signal generated in response to an output of the first sound stimulus through a detection electrode of the device;
Performing a tinnitus diagnosis for the user based on the EEG included in the detected biological signal; And
And outputting a second sound stimulus through the speaker and outputting a current stimulus through at least one current stimulus applying electrode of the device based on the result of the tinnitus diagnosis for the user, wherein the biosignal further comprises an electrocardiogram. A computer-readable recording medium comprising instructions for causing the processor to perform a method comprising. As a computer program stored in a computer-readable recording medium,
The computer program, when executed by a processor,
Outputting a first sound stimulus through a speaker of the device;
Detecting a user's bio-signal generated in response to an output of the first sound stimulus through a detection electrode of the device;
Performing a tinnitus diagnosis for the user based on the EEG included in the detected biological signal; And
And outputting a second sound stimulus through the speaker and outputting a current stimulus through at least one current stimulus applying electrode of the device based on the result of the tinnitus diagnosis for the user, wherein the biosignal further comprises an electrocardiogram. A computer program comprising instructions for causing the processor to perform a method comprising. In the device for personalized tinnitus treatment,
speaker; And
It includes a discharge port formed to output a first sound stimulus through the speaker to the outside, has a shape that can be mounted on a part of the user's ear, outputs a current or voltage stimulus, and responds to the output of the first sound stimulus And an electrode for detecting a user's bio-signal generated by
The biological signal is a device for personalized tinnitus treatment including an electrocardiogram.

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