KR101684689B1 - Blood collection device - Google Patents

Abstract

The present invention relates to a blood sampling device, and more particularly, to a blood sampling device, which can rapidly analyze blood by direct injection into a rapid blood collection and rapid diagnostic kit by an injection part, and is applied to a diagnostic kit at an economical price (5ul, 10ul, 15ul, 20ul or the like in the same structure) through a plurality of through holes, and the main body is detached using a break point, and then the detached main body is inserted into the buffer tube, And the blood contained in the accommodation part can be dispensed by the use of the pipette part. Therefore, it is convenient to use the blood collecting device for the purpose of collecting a lot of blood, and it is possible to collect and dispense blood by various methods, It can be used in kits, and is characterized by good practicality and efficiency.

Description

[0001] Blood collection device [0002]

The present invention relates to a blood sampling device, and more particularly, to a blood sampling device, which can rapidly analyze blood by direct injection into a rapid blood collection and rapid diagnostic kit by an injection part, and is applied to a diagnostic kit at an economical price (5ul, 10ul, 15ul, 20ul or the like in the same structure) through a plurality of through holes, and the main body is detached using a break point, and then the detached main body is inserted into the buffer tube, And the blood contained in the accommodation part can be dispensed by the use of the pipette part. Therefore, it is convenient to use the blood collecting device for the purpose of collecting a lot of blood, and it is possible to collect and dispense blood by various methods, The present invention relates to a blood sampling device which can be used in a kit and is excellent in practicality and efficiency.

Recently, a method of collecting body fluids without injecting an injection to detect various chemicals and biological substrates has attracted attention. This technique is possible because of the development of analytical techniques, and it is also possible that various components (pathogens, biologics, metabolites, drugs, etc.) and blood preparations contained in blood that are obtained with a syringe and are of physiological and / It is contained in body fluids such as sweat, tears, pericardial fluid, peritoneal fluid, pleural fluid, cerebrospinal fluid, stomach fluid, respiratory fluid, semen, synovial fluid, vomit fluid, ulcer drainage, ascites, saliva, This is possible because it is easier to obtain at low risk. Also, when using blood or blood products, the amount of blood needed to measure levels of various components of interest is relatively small compared to blood collected from many people.

In addition, saliva or urine samples may be advantageous for testing several physiological components of interest. For example, saliva or urine samples are sufficient to test if you are taking marijuana. Although marijuana is detected in the urine for up to 40 days after taking it, saliva samples are much more desirable than urine for detecting recent doses, since the evidence is only present for 48 hours.

Sampling and testing of body fluids typically consists of four steps: 1) collection of samples; 2) sample extraction from the collected material; 3) reacting the sample with the reactant; 4) Detection and / or measurement of physiologically or pathologically active components. In the past, it was common to use a swab or a device such as an absorbent or absorbent pad to absorb fluid to collect body fluids without a syringe. These harvesting devices were collected and placed in a container, and samples were then extracted in a suitable solvent using diffusion phenomenon by mechanical agitation (or without agitation). Sample extraction that does not use diffusion is very slow and takes a few minutes. If this process is promoted by agitation, impurities such as cotton or paper fibers are included in the extract along with the sample, and these impurities must be removed prior to the above three-step reaction.

At this time, a syringe or the like is generally used to extract (collect) the sample.

However, in the case of a syringe, an excessive amount can be sucked into the receiving portion when the sample is sucked, and it is difficult to finely control the dispensing amount of the received solution. In order to solve this problem, a method has been proposed in which a hole is formed at a predetermined height of the capillary structure for receiving the solution of the droplet so as to control the amount of the aqueous solution. However, since the capillary pressure of the syringe is higher than that of the sample in the reaction zone, there is a problem that the solution is not introduced into the reaction region or is interrupted.

In general, the diagnostic and blood analysis apparatus includes an injection port for injecting blood and a blood chamber for storing the injection port. However, when a wound is buried in the injection port for injecting blood, most of the blood is injected only around the injection port There is a problem that the loss of blooming becomes very large.

Korean Patent Laid-Open Publication No. 2010-0130121 Korean Patent Laid-Open Publication No. 2013-0054573

SUMMARY OF THE INVENTION The present invention has been made to solve the above-mentioned problems,

It is possible to rapidly analyze blood by rapid blood collection and direct contact with the rapid diagnostic kit by the injection part by the method of collecting blood, and it can be applied to the diagnostic kit at an economical price, After removing the main body part using a break point, the removed main body part is inserted into a buffer tube, diluted in a buffer by the osmotic principle, and analyzed by using a pipette part. It is convenient to use the blood collecting device for collecting the blood in a versatile manner because it can dispense the blood contained in the blood collecting part and can be used for various diagnostic kits because blood can be collected and dispensed by various methods, The purpose is to provide.

To achieve the above object, the present invention provides a blood sampling device,

A body portion;

A receiving portion formed inside the body portion and formed in a longitudinal direction from one side of the body portion to receive blood by a capillary function;

And an injection unit formed at one side of the main body and communicating with the receiving unit and having one side expanded so as to collect blood by surface tension and absorb the blood to the receiving unit side.

Further, the present invention provides a blood sampling device,

A body portion;

A receiving portion formed inside the body portion and formed in a longitudinal direction from one side of the body portion to receive blood by a capillary function;

An injection part formed on one side of the main body part and communicating with the receiving part, one side of which is expanded to collect blood by surface tension and absorb the blood to the receiving part side;

And a pipetting portion formed at an outer circumference of the main body portion to introduce blood into the receiving portion by internal pressure or to discharge the blood of the receiving portion through the injection portion. will be.

The body portion of the present invention is formed in a cylindrical shape and has a through hole communicating with a receiving portion formed in the inside of the body portion at its outer periphery, and a plurality of the through holes are formed at predetermined intervals in the longitudinal direction of the body portion, Wherein the amount of blood to be collected is adjusted at intervals of the holes, and the through holes are formed at right angles to the receiving portion.

Further, the pipette unit of the present invention is formed on the outer circumference of the main body portion having the through-hole, and the internal pressure is transmitted to the receiving portion through the through-hole to allow the blood to flow in or out .

In addition, a break point is formed on the outside of the body part of the present invention in order to remove the body part while collecting blood in the receiving part.

Further, the break point of the present invention is formed in a groove on the outside of the body, and is formed in a circumferential direction of the body so as to be smaller than the outer periphery of the body, so that the body can be easily removed. .

Further, the blood sampled by the blood sampling device of the present invention is diagnosed by being divided in the rapid diagnostic kit.

In addition, the handle portion is protrudingly formed integrally with the other side of the body portion of the present invention, so that the blood sampling device can be easily used.

As described above, the blood sampling device of the present invention is a method of collecting blood, which enables quick analysis of blood by direct injection into a rapid blood collection and rapid diagnostic kit by an injection unit and is applied to a diagnostic kit at an economical price (5ul, 10ul, 15ul, 20ul or the like in the same structure) through a plurality of through holes, and the main body is detached using a break point, and then the detached main body is inserted into the buffer tube, And the blood contained in the accommodation part can be dispensed by the use of the pipette part. Therefore, it is convenient to use the blood collecting device for the purpose of collecting a lot of blood, and it is possible to collect and dispense blood by various methods, It can be used in a kit, and practicality and efficiency are good.

1 is a perspective view showing a blood sampling device according to an embodiment of the present invention,
FIG. 2 is a perspective view showing a blood sampling device in which a pipette unit moves according to an embodiment of the present invention,
3 is a perspective view illustrating a blood sampling device in which a pipette part is removed according to an embodiment of the present invention,
4 is a cross-sectional view of a blood sampling device according to an embodiment of the present invention,
5 is an enlarged view showing part A of Fig.

The present invention having such characteristics can be more clearly described by the preferred embodiments thereof.

DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS Before describing in detail several embodiments of the present invention with reference to the accompanying drawings, it is to be understood that the present invention is not limited to the details of construction and the arrangement of components shown in the following detailed description or illustrated in the drawings will be. The invention may be embodied and carried out in other embodiments and carried out in various ways. It should also be noted that the device or element orientation (e.g., "front," "back," "up," "down," "top," "bottom, Expressions and predicates used herein for terms such as "left," " right, "" lateral," and the like are used merely to simplify the description of the present invention, Or that the element has to have a particular orientation. Also, terms such as " first "and" second "are used herein for the purpose of the description and the appended claims, and are not intended to indicate or imply their relative importance or purpose.

Therefore, the embodiments described in this specification and the configurations shown in the drawings are merely the most preferred embodiments of the present invention and do not represent all the technical ideas of the present invention. Therefore, It is to be understood that equivalents and modifications are possible.

FIG. 1 is a perspective view of a blood sampling device according to an embodiment of the present invention. FIG. 2 is a perspective view illustrating a blood sampling device in which a pipette section moves according to an embodiment of the present invention. FIG. FIG. 4 is a cross-sectional view showing a blood sampling device according to an embodiment of the present invention, and FIG. 5 is an enlarged view showing part A of FIG.

1 to 5, the blood sampling device 50 of the present invention includes a main body 10, a receiving portion 20, and an injection portion 20 for dispensing blood into a rapid diagnosis kit for diagnosis, (30), and a pipetting part (40).

1 to 5, the main body 10 is formed in a cylindrical shape and has a pair of through holes 11 (see FIG. 1), which are in communication with a receiving portion 20 formed inside the main body 10, The through hole 11 is formed at a right angle to the receiving portion 20 and communicates with the outside. At this time, the through holes 11 may be spaced apart from each other only on one side of the body portion 10, instead of one pair. That is, a plurality of through holes 11 are formed on the same horizontal line.

The pair of through holes 11 formed on the same line are further spaced a predetermined distance apart in the longitudinal direction of the main body portion 10 and are further formed with a pair of through holes 11, The amount of blood is adjusted every interval. That is, the amount of blood (5ul, 10ul, 15ul, 20ul) to be filled in the accommodating portion 20 can be determined for each interval of the through holes 11. [ At this time, when the blood to be filled in the accommodating portion 20 flows more than the capacity of the accommodating portion 20, the blood is discharged to the outside through the through hole 11.

The main body 10 has an injection part 30 integrally formed at one end and a handle 12 integrally formed at the other end to facilitate the use of the blood sampling device.

A break point 13 for detaching the main body 10 in a state where blood is collected in the accommodating portion 20 is further formed on the outside of the main body 10 and the break point 13 Is formed in a groove shape on the outer side of the body portion 10 and is formed in a groove shape long in the circumferential direction of the body portion 10 so that the circumference of the groove is smaller than the outer peripheral edge of the body portion 10, Can be easily removed.

Here, the removed main body 10 is put into a tube (not shown) containing a buffer, and the blood contained in the receiving part 20 escapes into the buffer by the principle of osmotic pressure and is diluted with the buffer. The blood diluted buffer is then dispensed into the diagnostic kit for analysis.

4 to 5, the accommodating portion 20 is formed inside the main body portion 10 and extends from one side of the main body portion 10 (one side where the injection portion 30 is formed) Is formed at a predetermined interval in the lengthwise direction of the body 10 to receive blood by a capillary function.

Here, the accommodating portion 20 is formed in accordance with the standard and communicates with the through-hole 11, and is capable of accommodating 5 ul of blood at intervals of the through-hole 11. As described above, the accommodating portion 20 of the present invention is formed as a space in which a total of 15 ul of blood can be filled.

1 to 5, the injection unit 30 is formed at one side of the main body 10 and communicates with the accommodation unit 20, and the injection unit 30 is configured to inject blood by surface tension The amount of the injection unit 30 is about 5 ul. At this time, the inner surface of the injection portion is formed into a curved line so as to generate surface tension.

In this case, the injection unit 30 is inverted in the form of an inverted cup, that is, in the form of an isosceles trapezoid or inverted upside down, so that the blood is taken up by the surface tension and moved to the receiving unit 20 side.

The pipetting portion 40 is formed on the outer circumference of the main body portion 10 as shown in Figs. 1 to 2 and Figs. 4 to 5 so as to press the body by external pressure, 40, and when the pressing body is released, a pulling pressure is generated in the pipette portion 40. [0053]

Here, the blood is introduced into the accommodation portion 20 by the pressure of the pipette portion 40, or the blood of the accommodation portion 20 is discharged through the injection portion 30. That is, the pipette 40 is formed on the outer circumference of the main body 10 having the through hole 11 so that the internal pressure of the pipette 40 is transmitted to the receiving part 20 through the through hole 11 So that the blood flows into or flows into the accommodating portion 20.

The pipette portion 40 is formed of a rubber material so as to generate pressure inside the pipette portion 40. The pipette portion 40 itself is elastically driven and a hollow portion having a predetermined size is formed therein, Pressure is generated in the portion.

The pipette portion 40 is formed on the outer circumference of the main body portion 10 and is movable in the longitudinal direction of the main body portion 10 so as to cover the through hole 11 of the main body portion 10, The inner pressure can be arbitrarily transmitted to the through-hole 11, thereby filling the receiving portion 20 with a desired amount of blood.

Hereinafter, an operation method of the blood sampling device described above will be described.

The method of operation of the blood sampling device of the present invention is such that the blood of about 5 ul is adsorbed by the surface tension of the injection part 30 when the injection part 30 is brought into contact with the blood to be sampled (first embodiment) And is introduced into the accommodating portion 20 by the capillary phenomenon of the accommodating portion 20 in that state.

A desired amount of blood can be collected in the accommodating portion 20 in the same manner as described above. In the present invention, blood of about 25 ul can be collected through the blood sampling device 50. That is, about 20 袖 l is accommodated in the accommodating portion 20, and 5 ul is taken in the injecting portion 30.

In order to discharge the collected blood to the outside, the break point 13 of the body 10 is cut to remove the blood-filled body 10, and the removed body 10 has a buffer ). At this time, the blood of the main body 10 escapes into the buffer by the principle of osmotic pressure and is diluted with the buffer.

The diluted buffer is then dispensed into a rapid diagnostic kit to diagnose and analyze the blood.

(Second embodiment)

When the pressure to be applied to the pipette 40 is released after the injection unit 30 is brought into contact with the blood to be sampled while pressing the outside of the pipette unit 40, a pressure is pulled inside the pipette unit 40, Blood is sucked through the portion 30 and filled in the accommodation portion 20. [

The pipette unit 40 is moved to collect the blood in the receiving unit 20 in accordance with a desired volume. That is, the sampling capacity of the blood varies depending on the position of the pipette unit 40. The pipette unit 40 is configured such that the pressure applied to the through-hole 11 is different depending on the position of the through-hole 11, The capacity will vary.

For example, when the through hole 11 is formed at the front side and the back side at the main body 10, when the pipette 40 is positioned in the through hole 11 at the rear side, Blood is filled up to the communicating receiving portion 20 and conversely when the pipette portion 40 is positioned and operated in the front through hole 11 and the blood is filled up to the receiving portion 20 communicated with the front through hole 11 And can be collected at different doses.

Here, the blood that is excessively introduced into the blood storing portion 20 by the pipette portion 40 is discharged to the outside through the through-hole 11, and only a predetermined amount of blood is collected in the storing portion 20.

At this time, pressure is applied to push the outside of the pipette part 40 to push the blood inside the pipette part 40, and the pressure is applied to the through hole 11 to the receiving portion 20 so that the blood in the receiving portion 20 is discharged to the outside.

10: main body part 11: through hole
12: Handle portion 13: Break point
20: accommodating portion 30: injecting portion
40: pipette part 50: blood collecting device

Claims (8)

In a blood sampling device,
A main body 10;
A receiving part 20 formed in the body part 10 and extending longitudinally from one side of the body part 10 to receive blood by a capillary function;
And an injection part 30 formed at one side of the main body part 10 and communicating with the accommodation part 20 and having one side expanded so as to collect blood by surface tension and absorb the blood to the accommodation part 20 side Respectively,
The main body 10 is formed in a cylindrical shape and has a through hole 11 communicating with a receiving portion 20 formed in the main body 10 at its outer periphery. And the through holes (11) are formed at right angles to the receiving portion (20). The blood collecting device according to claim 1, wherein the through holes (11) Device.
In a blood sampling device,
A main body 10;
A receiving part 20 formed in the body part 10 and extending longitudinally from one side of the body part 10 to receive blood by a capillary function;
An injection part 30 formed at one side of the main body part 10 and communicating with the receiving part 20 and having one side expanded to take blood by surface tension and absorb the blood to the receiving part 20 side;
A pipetting part 40 formed at the outer circumference of the main body part 10 to introduce blood into the accommodation part 20 by internal pressure or to discharge the blood of the accommodation part 20 through the injection part, ; ≪ / RTI >
The main body 10 is formed in a cylindrical shape and has a through hole 11 communicating with a receiving portion 20 formed in the main body 10 at its outer periphery. And the through holes (11) are formed at right angles to the receiving portion (20). The blood collecting device according to any one of claims 1 to 3, Device.
3. The method of claim 2,
The pipette portion 40 is formed on the outer circumference of the main body portion 10 having the through hole 11 so that the internal pressure is transmitted to the receiving portion 20 through the through hole 11, (Note).
3. The method according to claim 1 or 2,
Wherein a break point (13) for removing the main body (10) is formed on the outside of the main body part (10) while collecting blood in the receiving part (20).
5. The method of claim 4,
The break point 13 is formed in a groove on the outside of the body 10 and is formed in the circumferential direction of the body 10 to be smaller than the outer circumference of the body 10, Wherein the blood collection device is detachable.
3. The method according to claim 1 or 2,
Wherein the blood sampled by the blood sampling device (50) is diagnosed by frequency in the rapid diagnostic kit.
3. The method according to claim 1 or 2,
Wherein a handle (12) is integrally formed on the other side of the main body (10) so that the blood sampling device (50) can be easily used. delete

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