KR101479814B1 - Calcium-chitosan and manufacturing method of the same that, calcium-chitosan salt manufacturing method using the same that - Google Patents
Calcium-chitosan and manufacturing method of the same that, calcium-chitosan salt manufacturing method using the same that Download PDFInfo
- Publication number
- KR101479814B1 KR101479814B1 KR20120081982A KR20120081982A KR101479814B1 KR 101479814 B1 KR101479814 B1 KR 101479814B1 KR 20120081982 A KR20120081982 A KR 20120081982A KR 20120081982 A KR20120081982 A KR 20120081982A KR 101479814 B1 KR101479814 B1 KR 101479814B1
- Authority
- KR
- South Korea
- Prior art keywords
- calcium
- chitosan
- salt
- present
- same
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
- C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
- C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/40—Table salts; Dietetic salt substitutes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/015—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0003—General processes for their isolation or fractionation, e.g. purification or extraction from biomass
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Sustainable Development (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
본 발명은 칼슘이 함유되어 영양학적으로 우수한 칼슘-키토산 및 그 제조방법과, 이러한 키토산을 이용한 칼슘-키토산 소금을 제조하는 방법에 대한 것이다.
본 발명에 따르면, 갑각류의 껍질을 가공하여 제조되며, 갑각류의 껍질에 함유된 칼슘이 잔존되는 칼슘-키토산 및 그 제조방법과 이를 이용한 칼슘-키토산 소금을 제조하는 방법이 제공된다.The present invention relates to calcium-chitosan which is calcium-containing and has excellent nutrition, a process for producing the calcium-chitosan, and a method for producing calcium-chitosan salt using the chitosan.
According to the present invention, there is provided calcium-chitosan, which is manufactured by processing shell of crustacean and calcium contained in the shell of crustacean remains, a process for producing the same, and a method for producing calcium-chitosan salt using the same.
Description
본 발명은 칼슘-키토산 및 그 제조방법과 이를 이용한 키토산 소금의 제조방법에 관한 것으로서, 칼슘이 함유되어 영양학적으로 우수한 칼슘-키토산 및 그 제조방법과, 이러한 키토산을 이용한 칼슘-키토산 소금을 제조하는 방법에 관한 것이다.
The present invention relates to a calcium-chitosan, a method for producing the same, and a method for producing the chitosan salt using the same, which comprises calcium-containing calcium-chitosan, ≪ / RTI >
키토산은 키틴을 인체에 쉽게 흡수되도록 가공한 물질이다. 구체적으로는, 키틴이 함유된 게나 새우와 같은 갑각류의 외피를 묽은 염산과 알칼리수용액에 순차적으로 침지시켜 칼슘과 단백질을 제거한 다음, 탈아세틸화시켜 제조된다. Chitosan is a substance that is processed to easily absorb chitin into human body. Specifically, it is prepared by sequentially immersing the outer shell of crustaceans such as chrysanthemums containing chitin in a diluted hydrochloric acid and an aqueous alkali solution to remove calcium and protein, and then deacetylating the calcium and protein.
이러한 키토산은 항암작용, 면역력강화, 혈당·혈압조절, 항균기능 등을 가지며, 체내에 축적된 중금속과 콜레스테롤을 배출시키며, 체질을 약알칼리성으로 개선시킬 뿐만 아니라 피부보습효과도 우수하다. 따라서 이러한 우수한 기능을 가지는 키토산을 다양한 제품에 적용하고자 하는 노력이 이루어지고 있다. These chitosan have anticancer effect, strengthened immunity, control blood sugar and blood pressure, antibacterial function, release heavy metals and cholesterol accumulated in the body, improve not only alkalinity but also skin moisturizing effect. Therefore, efforts have been made to apply chitosan having such excellent functions to various products.
한편, 키토산을 이용한 제품의 제조시에, 제품에 따라 칼슘이 요구되기도 하는데, 이러한 경우에는 제품 제조과정에서 별도로 칼슘을 추가하여야 한다. 그러나 전술한 바와 같이, 키틴을 키토산으로 가공하는 과정에서 칼슘을 인위적으로 제거하고, 추후 키토산을 이용하여 제품을 제조하는 과정에서 별도로 칼슘을 추가하는 것은 비경제적이다. On the other hand, when manufacturing a product using chitosan, calcium may be required depending on the product. In such a case, calcium should be separately added in the manufacturing process of the product. However, as described above, it is uneconomical to artificially remove calcium in the course of processing chitin into chitosan, and to add calcium separately in the course of manufacturing products using chitosan.
또한, 키토산을 다양한 제품에 적용하기 위해서는 제조되는 제품의 성상에 따라 키토산을 미세한 분말상태로 분쇄할 필요도 있다. 그러나 종래의 키토산은 칼슘이 제거되어 상당히 부드럽고 유연하기 때문에 미세한 분말상태로 분쇄가 쉽지 않다. 경우에 따라 게나 새우의 껍질을 미리 분쇄하여 키토산으로 가공하여 키토산 분말을 수득하기도 한다. 그러나 이 경우에는 가공과정에서 피가공물, 즉 껍질분말이 유실되어 키토산의 수득율이 감소된다.
In order to apply chitosan to various products, it is also necessary to crush chitosan into a fine powder state depending on the properties of the product to be produced. However, the conventional chitosan is very soft and flexible because calcium is removed, so that it is not easy to crush into a fine powder state. In some cases, the bark of a shrimp or a shrimp may be previously pulverized and processed into chitosan to obtain a chitosan powder. In this case, however, the workpiece, that is, the shell powder, is lost during processing and the yield of chitosan is reduced.
본 발명은 칼슘 키토산 및 그 제조방법과 이를 이용한 키토산 소금의 제조방법에 관한 것으로서, 칼슘이 제거되지 않고 잔존되므로 영양학적으로 우수하고 미세한 분말로 가공이 용이한 칼슘-키토산과 이를 제조하기 위한 환경친화적이고 경제적인 제조방법과, 이러한 칼슘-키토산과 해양심층수를 이용하여 영양학적으로 우수한 칼슘-키토산 소금을 제조하는 방법을 제공하는 것이다.
The present invention relates to calcium chitosan and its preparation method, and a method for producing chitosan salt using the same. The present invention relates to calcium-chitosan which is excellent in nutrition and easy to be processed into fine powder and is environmentally friendly And a method for producing calcium-chitosan salt superior in nutrition using such calcium-chitosan and deep seawater.
본 발명의 일 특징에 따르면, 갑각류의 껍질을 탈단백질 및 탈아세틸화하여 제조되어, 갑각류의 껍질에 함유된 칼슘이 잔존되는 칼슘-키토산이 제공된다.
According to one aspect of the present invention there is provided calcium-chitosan which is prepared by deproteinizing and deacetylating the shell of a crustacean, wherein the calcium contained in the shell of the crustacean remains.
본 발명의 다른 특징에 따르면, 갑각류의 껍질을 세척하는 과정과, 세척된 갑각류의 껍질에 함유된 단백질을 제거하는 과정과, 상기 과정에서 수득되는 고형분을 세척하는 과정과, 세척된 고형분을 탈아세틸화하여 칼슘이 잔존되는 고형의 칼슘-키토산을 수득하는 과정과, 상기 과정에서 수득된 칼슘-키토산을 세척하고 건조하는 과정을 포함하여 이루어진 것을 특징으로 하는 칼슘이 잔존되는 칼슘-키토산의 제조방법이 제공된다.
According to another aspect of the present invention, there is provided a method for washing a crustacean, comprising the steps of washing the crust of the crustacean, removing the protein contained in the crust of the washed crustacean, washing the solid obtained in the process, The present invention relates to a method for producing calcium-chitosan, which comprises the steps of: obtaining calcium-chitosan having a solid content in the form of calcium and remaining solid calcium; and washing and drying the calcium- / RTI >
본 발명의 다른 특징에 따르면, 갑각류의 껍질을 세척하는 과정과, 세척된 갑각류의 껍질에 함유된 단백질을 제거하는 과정과, 상기 과정에서 수득된 고형분을 세척하는 과정과, 세척된 고형분을 탈아세틸화하여 칼슘이 잔존되는 고형의 칼슘-키토산을 수득하는 과정과, 상기 과정에서 수득된 칼슘-키토산을 세척하고 건조하는 과정과, 상기 건조된 칼슘-키토산을 유기산에 용해시키는 과정과, 상기 과정에서 수득된 칼슘-키토산 용액을 해수와 혼합하는 과정과, 상기 해수혼합물을 농축시켜 칼슘-키토산이 혼합된 소금을 석출시키는 과정과, 상기 소금을 탈수, 건조시키는 과정을 포함하여 이루어진 것을 특징으로 하는 칼슘-키토산 소금의 제조방법이 제공된다.
According to another aspect of the present invention, there is provided a method for washing a crustacean, comprising the steps of washing the crust of the crustacean, removing the protein contained in the crust of the washed crustacean, washing the solid obtained in the process, A step of washing and drying the calcium-chitosan obtained in the above step, a step of dissolving the dried calcium-chitosan in an organic acid, and a step of dissolving the dried calcium- Mixing the obtained calcium-chitosan solution with seawater, concentrating the seawater mixture to precipitate salt mixed with calcium-chitosan, and dehydrating and drying the salt. - a method for producing chitosan salt is provided.
본 발명의 또 다른 특징에 따르면, 상기 해수는 해양심층수로 이루어진 것을 특징으로 하는 칼슘-키토산 소금의 제조방법이 제공된다.
According to another aspect of the present invention, there is provided a method for producing calcium-chitosan salt, wherein the sea water is composed of deep ocean water.
이상과 같은 구성을 가지는 본 발명에 의한 키토산은 키틴을 키토산으로 가공하는 과정에서 칼슘이 잔존되어 칼슘이 함유된다. 이러한 본 발명에 의한 칼슘-키토산은 가공과정에서 칼슘을 제거하기 위한 공정이 요구되지 않으므로 가공공정이 종래의 키토산가공공정에 비해 간단하고, 가공시간도 단축되므로 생산성이 향상된다. 또한, 종래에는 키틴에서 칼슘을 제거하기 위해 염산을 사용하였고, 이에 따라 염산폐수가 발생되어 환경오염이 유발되었으나, 본 발명은 이러한 염산폐수가 발생되지 않으므로 환경친화적이고, 폐수처리를 위한 추가비용도 발생되지 않으므로 경제적이다. In the chitosan according to the present invention having the above-described structure, calcium is retained in the step of processing chitin into chitosan, and calcium is contained. Since the calcium-chitosan according to the present invention does not require a process for removing calcium in the process, the process is simpler than the conventional chitosan process and the productivity is improved because the process time is shortened. In the prior art, hydrochloric acid was used to remove calcium from chitin, and hydrochloric acid wastewater was generated thereby causing environmental pollution. However, since the present invention does not generate such hydrochloric acid wastewater, it is environmentally friendly, and the additional cost It is economical because it does not occur.
특히, 본 발명에 의한 칼슘-키토산은 다른 제품으로 가공시 추가로 칼슘을 첨가하기 않아도 칼슘이 보충되므로 경제적이다. 또한, 본 발명에 함유된 칼슘은 게껍질 등에 함유된 천연칼슘이므로 체내 흡수율도 우수하다. 뿐만 아니라 칼슘이 함유되어 키토산이 종래의 키토산에 비해 딱딱하기 때문에 키토산을 분쇄하여 분말상으로 가공하기가 용이한 장점을 가진다. 따라서 미세한 분말로 분쇄가 가능하므로, 제조되는 제품의 성상에 상관없이 적용이 가능하다. In particular, the calcium-chitosan according to the present invention is economical because it is supplemented with calcium even when no additional calcium is added when processing it into another product. In addition, since calcium contained in the present invention is natural calcium contained in crab shells and the like, its absorption rate in the body is also excellent. In addition, since chitosan contains calcium and is harder than conventional chitosan, chitosan is easily pulverized and processed into a powder form. Therefore, the powder can be pulverized into fine powder, so that it can be applied regardless of the properties of the product to be manufactured.
이러한 본 발명에 의한 칼슘-키토산은 다양한 제품에 적용이 가능하다. 키토산과 칼슘은 각각 혈압조절효과가 있으므로 본 발명에 의한 칼슘-키토산은 칼슘과 키토산에 의해 혈압조절에 대한 시너지효과를 얻을 수 있으므로 혈압조절효과가 우수하다. 따라서 본 발명에 의한 칼슘-키토산은 고혈압 관련 약제나 식품에 적용이 적합하다. The calcium-chitosan according to the present invention can be applied to various products. Since chitosan and calcium each have a blood pressure-controlling effect, the calcium-chitosan according to the present invention can exert a synergistic effect on blood pressure control by calcium and chitosan, and thus has excellent blood pressure control effect. Therefore, the calcium-chitosan according to the present invention is suitable for application to medicines and foods for hypertension.
또한, 본 발명을 소금에 적용하면, 칼슘과 키토산이 함유된 영양학적, 기능적으로 우수한 소금을 얻을 수 있다. 특히, 본 발명에서는 소금의 제조시 칼슘-키토산을 유기산에 용해시켜 사용하는데, 키토산이 유기산에 용해되면 저분자화되어 체내에서의 분해, 흡수율이 높아지므로, 본 발명에 의해 제조된 칼슘-키토산 소금은 키토산의 흡수율이 높은 고품질의 소금이라 할 수 있다. 더욱이 해수로 해양심층수를 사용하기 때문에 천연 미네랄성분이 풍부한 소금을 얻을 수 있다.
Further, when the present invention is applied to salt, nutritionally and functionally excellent salt containing calcium and chitosan can be obtained. Particularly, in the present invention, calcium-chitosan is dissolved in organic acid in the production of salt. When chitosan is dissolved in organic acid, it is converted into low molecular weight and decomposition and absorption rate is increased in the body. It can be said that it is high quality salt with high absorption rate of chitosan. Moreover, since deep sea water is used as seawater, it is possible to obtain salt rich in natural minerals.
도 1은 본 발명에 의한 칼슘-키토산 제조공정을 보인 공정도
도 2는 본 발명에 의한 칼슘-키토산 소금의 제조공정을 공정도BRIEF DESCRIPTION OF THE DRAWINGS FIG. 1 is a process diagram showing a process for producing calcium-
Fig. 2 is a view showing a process for producing calcium-chitosan salt according to the present invention
이하에서 도면을 참조하여 본 발명의 바람직한 실시예를 설명한다.Hereinafter, preferred embodiments of the present invention will be described with reference to the drawings.
도 1은 게껍질을 이용하여 칼슘-키토산을 제조하는 과정을 보인 공정도이다. 1 is a process diagram showing a process for producing calcium-chitosan using crab shells.
본 발명에 따른 칼슘-키토산은 다음과 같은 방법으로 제조된다. 먼저, 수집된 게껍질을 세척하여 준비한다. 물론, 게껍질 뿐만 아니라 새우껍질, 갑오징어뼈 등 다양한 갑각류의 껍질이 사용될 수 있다. 세척된 껍질에서 단백질을 제거한다. 단백질제거과정은 상기 껍질을 5% 정도의 묽은 수산화나트륨수용액에 2~6시간 정도 침지시켜 이루어진다. 이와 같이 하면 게껍질 속의 단백질이 가수분해되어 제거된다. 게껍질 속의 단백질이 가수분해되면 액체는 버리고, 고형분만 수거하여 세척한다. The calcium-chitosan according to the present invention is prepared in the following manner. First, the collected crab shells are prepared by washing. Of course, shells of crab shells, such as shrimp shells and squid bones, as well as crab shells, can be used. Remove protein from the washed skin. The protein removal process is carried out by soaking the shell in a 5% aqueous solution of sodium hydroxide for 2 to 6 hours. In this way, proteins in the crab shells are hydrolyzed and removed. When the protein in the crab shell hydrolyzes, the liquid is discarded and only the solid is collected and washed.
이어서 수거된 고형분을 탈아세틸화한다. 탈아세틸화는 수거된 고형분을 50% 정도의 진한 수산화나트륨수용액에 침지시켜서 100℃ 정도로 가열하여 이루어진다. 이러한 처리는 2~6시간 정도 행하여진다. 상기 과정 후 처리된 액체를 버리고, 잔존되는 고형분을 수거하는데, 수거된 고형분은 칼슘이 잔존되는 칼슘-키토산이다. 수거된 칼슘-키토산을 세척하고, 건조시켜서 칼슘-키토산 완제품을 수득한다. 필요에 따라서는, 탈아세틸화 후에, 50%의 수산화나트륨수용액을 버리고 수득된 고형분 즉, 칼슘-키토산에 물을 공급하고, 100℃ 정도로 가열하여 수득된 칼슘-키토산을 재처리한다. 탈아세틸화 후에 50%의 수산화나트륨수용액을 버리고 물을 다시 공급하면 잔존되는 수산화나트륨이 희석되어 3~7% 정도의 수산화나트륨수용액이 얻어지고, 이를 가열함에 따라 칼슘-키토산에 잔존되는 단백질이 제거되고, 탈아세틸화가 더 진행되어 탈아세틸화도가 높은 칼슘-키토산이 얻어진다. The collected solid is then deacetylated. Deacetylation is accomplished by immersing the collected solid in an aqueous solution of about 50% concentrated sodium hydroxide and heating it to about 100 ° C. This process is performed for about 2 to 6 hours. The treated liquid is discarded and the remaining solid content is collected. The collected solid content is calcium-chitosan in which calcium remains. The collected calcium-chitosan is washed and dried to obtain a calcium-chitosan article. If necessary, after the deacetylation, the calcium-chitosan obtained by discarding the 50% aqueous solution of sodium hydroxide and heating to about 100 캜 by supplying water to the obtained solid fraction, that is, calcium-chitosan, is reprocessed. After deacetylation, 50% sodium hydroxide aqueous solution is discarded and water is supplied again. The remaining sodium hydroxide is diluted to obtain an aqueous solution of sodium hydroxide of about 3 to 7%, and the protein remaining in calcium-chitosan is removed And deacetylation proceeds further to obtain calcium-chitosan having a high degree of deacetylation.
이와 같이 하여 얻어진 칼슘-키토산은 단백질을 비롯하여 이물질은 제거되고, 칼슘은 잔존되므로 기존의 칼슘이 제거된 키토산에 비해 경질이다. 종래 칼슘이 제거된 키토산은 부드럽고 유연한 상태이기 때문에 미세한 분말로 분쇄가 쉽지 않은 단점을 가지는데, 본 발명에 의한 칼슘-키토산은 함유된 칼슘에 의해 다소 딱딱한 경질이기 때문에 분쇄가 용이한 장점을 가진다. 따라서 미세한 분말로 가공이 가능이 가능하므로 제품의 성상에 구애받지 않고 적용이 가능하다. The calcium-chitosan thus obtained is harder than the existing calcium-removed chitosan since the protein and other foreign substances are removed and calcium remains. Since chitosan in which calcium has been removed conventionally is in a soft and flexible state, it is difficult to crush with fine powder. Calcium-chitosan according to the present invention has an advantage of easy crushing because it is hard and hard because of calcium contained therein. Therefore, it can be processed into fine powder, so it can be applied regardless of the characteristics of the product.
이와 같이 제조된 칼슘-키토산은 식품, 화장품, 사료 등 다양한 분야에 적용이 가능하다. 특히, 본 발명에 의한 칼슘-키토산은 혈압조절기능이 우수하다. 키토산은 체내에서 혈압상승을 유발하는 Cl-를 흡착하여 체외로 배출시켜 혈압강화를 도모하며, 칼슘 역시 혈관수축과 이완에 관여하는데, 칼슘이 부족하면 혈압이 상승된다. 이와 같이 본 발명에 의한 칼슘-키토산은 각각 혈압조절기능이 있는 칼슘과 키토산이 함께 존재되므로 칼슘과 키토산에 의해 혈압조절에 대한 시너지효과를 얻을 수 있다. 따라서 혈압조절효과가 우수하므로, 고혈압관련 치료제나 식품에 적용이 바람직하다. 본 발명에 함유된 칼슘은 게껍질에 함유된 천연칼슘이므로 흡수율도 높은 장점을 가진다. The thus prepared calcium-chitosan can be applied to various fields such as food, cosmetics, and feed. Particularly, the calcium-chitosan according to the present invention has excellent blood pressure control function. Chitosan absorbs Cl - , which causes blood pressure rise in the body, and excretes it out of the body to enhance blood pressure. Calcium also participates in vasoconstriction and relaxation. When calcium is insufficient, blood pressure rises. In the calcium-chitosan according to the present invention, since calcium and chitosan having a blood pressure-controlling function coexist together, a synergistic effect on blood pressure control can be obtained by calcium and chitosan. Therefore, it is preferable to be applied to a therapeutic agent or food for hypertension, since the blood pressure control effect is excellent. Since calcium contained in the present invention is natural calcium contained in the crab shell, it has a high absorption rate.
전술한 바와 같이, 칼슘-키토산은 다양한 제품에 적용될 수 있으나, 소금을 예로 들어 보면 다음과 같다. 전술한 방법으로 제조된 칼슘-키토산을 이용하여 소금을 제조하는데, 구체적인 방법을 살펴보면 다음과 같다.As described above, calcium-chitosan can be applied to various products, but examples of salt are as follows. The salt is prepared using the calcium-chitosan prepared by the above-mentioned method. Specific methods will be described below.
상기 칼슘-키토산 분말을 유기산에 용해시켜서 키토산용액을 제조한다. 유기산으로는 아세트산, 구연산, 아스코르브산 등이 사용된다. 경우에 따라서는 칼슘-키토산을 분쇄하지 않고 덩어리 상태로 유기산에 용해시켜 사용할 수도 있다. 칼슘-키토산을 유기산에 용해시키면, 키토산이 저분자화되어 키토산의 흡수율이 높아진다. The calcium-chitosan powder is dissolved in an organic acid to prepare a chitosan solution. As the organic acid, acetic acid, citric acid, ascorbic acid and the like are used. In some cases, calcium-chitosan may be dissolved in an organic acid in a lump state without being pulverized. When calcium-chitosan is dissolved in an organic acid, the chitosan becomes low in molecular weight and the absorption rate of chitosan becomes high.
이러한 칼슘-키토산용액을 준비된 해수에 혼합하여 소금을 제조한다. 바람직하게는 해수로 해양심층수를 사용한다. 해양심층수란 햇빛이 도달되지 않는 수심 200m 이하, 깊은 곳의 바닷물이다. 이러한 해양심층수는 표층수와의 밀도차에 의해 섞이지 않고 거대한 층을 이룬다. 이러한 해양심층수는 대장균이나 기타 병원균이 존재하지 않는 청정자원이며, 미네랄이 풍부하게 함유되어 있다. 따라서 본 발명에서는 이러한 해양심층수를 사용함으로써, 미네랄이 풍부한 키토산 소금을 제조한다. The calcium-chitosan solution is mixed with the prepared seawater to produce salt. Deep sea water is preferably used as seawater. Deep ocean water is deeper than 200 meters below sea level where sunlight can not reach. These deep ocean waters are not mixed by density difference with surface water, but form a huge layer. These marine deep seawater is a clean resource that does not contain E. coli or other pathogens, and is rich in minerals. Therefore, in the present invention, chitosan salt rich in minerals is produced by using such deep sea water.
칼슘-키토산 분말을 유기산에 녹인 칼슘-키토산용액을 해양심층수에 혼합한 후, 일반적인 소금제조방법으로 동일한 방법으로 농축시켜 소금과 칼슘-키토산을 석출시킨다. 해양심층수를 미리 농축시켜 사용하면, 소금제조시간을 단축시킬 수 있는 장점이 있다. 석출된 소금을 탈수, 건조시켜 칼슘-키토산이 함유된 소금 완제품을 얻는다.The calcium-chitosan solution obtained by dissolving the calcium-chitosan powder in the organic acid is mixed with the deep-sea water and then concentrated in the same manner as the conventional salt production method to precipitate the salt and the calcium-chitosan. The use of concentrated deep sea water in advance has the advantage of shortening the salt production time. The precipitated salt is dehydrated and dried to obtain a salt-finished product containing calcium-chitosan.
제조된 소금에 있어서 칼슘과 키토산의 함량이 높을수록 소금의 영양과 기능이 향상될 것이나 키토산 함량이 높으면, 소금에서 키토산 고유의 떫은맛이 강하게 느껴지고, 소금의 용해도도 저하된다. 따라서 키토산의 함량이 높은 소금을 요리용으로 사용하면, 음식의 국물이 혼탁해 질 수도 있고, 키토산의 떫은맛으로 음식 맛이 저하될 수도 있다. 이러한 이유 등으로 인해 소금의 용도에 따라 키토산의 함량이 조절될 필요가 있다. 이를 고려하여 칼슘-키토산용액과 해수의 혼합량을 조절한다. The higher the content of calcium and chitosan in the prepared salt, the better the nutrition and function of the salt. However, the higher the chitosan content, the stronger the salty taste of chitosan in the salt and the lower the solubility of the salt. Therefore, if salt of high content of chitosan is used for cooking, the soup of the food may become turbid, and the taste of the food may be deteriorated due to the bitter taste of chitosan. For these reasons, the content of chitosan needs to be controlled depending on the use of the salt. Considering this, the mixing amount of calcium-chitosan solution and seawater is controlled.
본 발명에 의해 제조된 칼슘-키토산 소금은 요리용, 미용용, 사료용 등 다양한 용도로 사용이 가능하다. The calcium-chitosan salt produced by the present invention can be used for various purposes such as cooking, cosmetic, feed and the like.
Claims (4)
A process of washing the crust of the crustacean, a process of removing proteins contained in the crust of the crushed crustacean, a process of washing the solid content obtained in the process, and a process of washing the washed solid content with deacetylation, The method of claim 1, wherein the calcium-chitosan solution obtained in the above step is dissolved in an aqueous solution of sodium chloride, Mixing the calcium-chitosan-containing salt and the calcium-chitosan-containing salt; and concentrating the seawater mixture to precipitate the salt mixed with calcium-chitosan; and dehydrating and drying the salt.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20120081982A KR101479814B1 (en) | 2012-07-26 | 2012-07-26 | Calcium-chitosan and manufacturing method of the same that, calcium-chitosan salt manufacturing method using the same that |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20120081982A KR101479814B1 (en) | 2012-07-26 | 2012-07-26 | Calcium-chitosan and manufacturing method of the same that, calcium-chitosan salt manufacturing method using the same that |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20140013728A KR20140013728A (en) | 2014-02-05 |
| KR101479814B1 true KR101479814B1 (en) | 2015-01-06 |
Family
ID=50264112
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR20120081982A Expired - Fee Related KR101479814B1 (en) | 2012-07-26 | 2012-07-26 | Calcium-chitosan and manufacturing method of the same that, calcium-chitosan salt manufacturing method using the same that |
Country Status (1)
| Country | Link |
|---|---|
| KR (1) | KR101479814B1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20190061828A (en) | 2017-11-27 | 2019-06-05 | 이보균 | Method for producing chitosan for forage use |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05271303A (en) * | 1992-03-26 | 1993-10-19 | Bankaku Souhonpo:Kk | Production of chitin, chitosan and calcium salt thereof |
| KR20000003190A (en) * | 1998-06-26 | 2000-01-15 | 서주원 | New biological agricultural chemicals containing calcium and manufacturing method |
| KR20010029143A (en) * | 1999-09-29 | 2001-04-06 | 노홍균 | Preparation of Chitosan with High Degree of Deacetylation and Viscosity |
| KR20100135265A (en) * | 2008-03-19 | 2010-12-24 | 아그라테크 인터내셔널, 인코포레이티드 | Chitosan production method |
-
2012
- 2012-07-26 KR KR20120081982A patent/KR101479814B1/en not_active Expired - Fee Related
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH05271303A (en) * | 1992-03-26 | 1993-10-19 | Bankaku Souhonpo:Kk | Production of chitin, chitosan and calcium salt thereof |
| KR20000003190A (en) * | 1998-06-26 | 2000-01-15 | 서주원 | New biological agricultural chemicals containing calcium and manufacturing method |
| KR20010029143A (en) * | 1999-09-29 | 2001-04-06 | 노홍균 | Preparation of Chitosan with High Degree of Deacetylation and Viscosity |
| KR20100135265A (en) * | 2008-03-19 | 2010-12-24 | 아그라테크 인터내셔널, 인코포레이티드 | Chitosan production method |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20190061828A (en) | 2017-11-27 | 2019-06-05 | 이보균 | Method for producing chitosan for forage use |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20140013728A (en) | 2014-02-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Bruno et al. | Green and innovative techniques for recovery of valuable compounds from seafood by-products and discards: A review | |
| CN105622781B (en) | A kind of method of chitin in eutectic ionic liquid extraction shrimp and crab shells | |
| CN103583931B (en) | Ultrasonic defluorination method for whole euphausia superba | |
| CN104126807B (en) | Method for continuously producing composite amino acid short peptide chelated calcium and chitin by using waste catering shrimp shells | |
| Trung et al. | Bioactive compounds from by-products of shrimp processing industry in Vietnam | |
| CN104304411A (en) | Freshness-keeping and water-retaining agent for prawns | |
| CN102086464B (en) | Method for preparing chitin | |
| Abraham et al. | Extraction of agar and alginate from marine seaweeds in red sea region | |
| CN105087729A (en) | Tuna bone collagen peptide preparation method | |
| CN104016854B (en) | A kind of take abalone shells as the citrate of lime prepared of raw material and method | |
| CN102732592A (en) | Method for preparing freshwater fish bone gelatin by enzyme process | |
| CN105249434A (en) | Method for preparing natural alginate oligosaccharide water-retaining agent by utilizing abalone visceral enzyme liquid | |
| CN106262575A (en) | A kind of low value Portunustrituberculatus prepares the production technology of seafood condiment | |
| Iñiguez-Moreno et al. | Valorization of fishery industry waste: Chitosan extraction and its application in the industry | |
| KR101479814B1 (en) | Calcium-chitosan and manufacturing method of the same that, calcium-chitosan salt manufacturing method using the same that | |
| CN106942647A (en) | One breeder tail crab pin preparation technology | |
| CN105685198A (en) | Method for removing mucus on surface of river snail meat | |
| JP2019193617A (en) | Manufacturing method of food additive based on silicon | |
| CN102219767B (en) | Method for preparing calcium ascorbate by utilizing shrimp shells | |
| JP2011030531A (en) | Method for making dried "sea cucumber" as powder, and method for making the same as extract by enzymatic decomposition | |
| CN103947818A (en) | Preparation method of squid active peptide | |
| JP4468665B2 (en) | Production method of plant chitosan | |
| CN104207269A (en) | Processing process of lotus root juice drink | |
| WO2014209101A3 (en) | Method of obtaining gelatin from aquatic animals | |
| CN108030002A (en) | A kind of instant seasoning fish block that raw meat is removed using biology enzyme and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A201 | Request for examination | ||
| PA0109 | Patent application |
Patent event code: PA01091R01D Comment text: Patent Application Patent event date: 20120726 |
|
| PA0201 | Request for examination | ||
| PG1501 | Laying open of application | ||
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20140327 Patent event code: PE09021S01D |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20141026 Patent event code: PE09021S01D |
|
| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
Patent event code: PE07011S01D Comment text: Decision to Grant Registration Patent event date: 20141212 |
|
| GRNT | Written decision to grant | ||
| PR0701 | Registration of establishment |
Comment text: Registration of Establishment Patent event date: 20141230 Patent event code: PR07011E01D |
|
| PR1002 | Payment of registration fee |
Payment date: 20141230 End annual number: 3 Start annual number: 1 |
|
| PG1601 | Publication of registration | ||
| FPAY | Annual fee payment |
Payment date: 20171017 Year of fee payment: 4 |
|
| PR1001 | Payment of annual fee |
Payment date: 20171017 Start annual number: 4 End annual number: 4 |
|
| LAPS | Lapse due to unpaid annual fee | ||
| PC1903 | Unpaid annual fee |
Termination category: Default of registration fee Termination date: 20191010 |