KR101361569B1 - 피부 진정 및 통전용 화장료 조성물 및 이의 제조 방법 - Google Patents
피부 진정 및 통전용 화장료 조성물 및 이의 제조 방법 Download PDFInfo
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- KR101361569B1 KR101361569B1 KR1020120065152A KR20120065152A KR101361569B1 KR 101361569 B1 KR101361569 B1 KR 101361569B1 KR 1020120065152 A KR1020120065152 A KR 1020120065152A KR 20120065152 A KR20120065152 A KR 20120065152A KR 101361569 B1 KR101361569 B1 KR 101361569B1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9794—Liliopsida [monocotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Emergency Medicine (AREA)
- Dermatology (AREA)
- Zoology (AREA)
- Cosmetics (AREA)
Abstract
Description
원 료 |
ICID | 비교예 | 비교예 | 비교예 | 비교예 | 비교예 | 비교예 | 비교예 |
CAS NO. | 1 | 2 | 3 | 4 | 5 | 6 | 7 | |
정제수 | 7732-18-5 | 86.2748 | 86.2748 | 83.2748 | 81.8248 | 81.2878 | 81.277 | 88.275 |
글리세린 | 56-81-5 | X | 5 | 5 | 5 | 5 | 5 | X |
부틸렌글라이콜 | 107-88-0 | 5 | X | 5 | 5 | 5 | 5 | 5 |
디메치콘 | 9006-65-9 | 1 | 1 | X | 1 | 1 | 1 | X |
악마의발톱뿌리추출물 | 84988-65-8 | 1 | 1 | X | 1 | 1 | 1 | X |
병풀추출물 | 84696-21-9 | 0.5 | 0.5 | 0.5 | X | 0.5 | 0.5 | 0.5 |
달팽이점액여과물 | CTFA ID | 0.05 | 0.05 | 0.05 | X | 0.05 | 0.05 | 0.05 |
양파추출물 | 8054-39-5 | 0.01 | 0.01 | 0.01 | 0.01 | X | 0.01 | 0.01 |
프롤린 | 147-85-3 | 0.002 | 0.002 | 0.002 | 0.002 | X | 0.002 | 0.002 |
강황추출물 | 84775-52-0 | 0.001 | 0.001 | 0.001 | 0.001 | X | 0.001 | 0.001 |
마치현추출물 | 90083-07-1 | 0.001 | 0.001 | 0.001 | 0.001 | 0.001 | X | 0.001 |
위치하젤수 |
CFTA ID | 0.001 |
0.001 |
0.001 |
0.001 |
0.001 |
X | 0.001 |
9415 | ||||||||
셀러리추출물 | CFTA ID: | 0.0001 | 0.0001 | 0.0001 | 0.0001 | 0.0001 | X | 0.0001 |
양배추잎추출물 | 89958-13-4 | 0.0001 | 0.0001 | 0.0001 | 0.0001 | 0.0001 | X | 0.0001 |
기타 첨가물 | 6.16 | 6.16 | 6.16 | 6.16 | 6.16 | 6.16 | 6.16 | |
Total | 100 | 100 | 100 | 100 | 100 | 100 | 100 |
원 료 |
ICID | 비교예 | 비교예 | 비교예 | 실험예 | 실험예 | 실험예 | 실험예 |
CAS NO | 8 | 9 | 10 | 1 | 2 | 3 | 4 | |
정제수 | 7732-18-5 | 100 | 100 | 100 | 93.84 | 93.84 | 76.5918 | 81.275 |
글리세린 | 56-81-5 | X | X | X | 4 | 4.5 | 5 | 5 |
부틸렌글라이콜 | 107-88-0 | 5 | 5 | 5 | 2 | 4 | 8 | 5 |
디메치콘 | 9006-65-9 | 1 | 1 | 1 | 0.5 | 1 | 2 | 1 |
악마의발톱뿌리추출물 | 84988-65-8 | 1 | 1 | 1 | 0.2 | 0.5 | 1 | 1 |
병풀추출물 | 84696-21-9 | X | 0.5 | 0.5 | 0.2 | 0.5 | 1 | 0.5 |
달팽이점액여과물 | CTFA ID | X | 0.05 | 0.05 | 0.02 | 0.1 | 0.2 | 0.05 |
양파추출물 | 8054-39-5 | 0.01 | X | 0.01 | 0.005 | 0.02 | 0.04 | 0.01 |
프롤린 | 147-85-3 | 0.002 | X | 0.002 | 0.001 | 0.0015 | 0.002 | 0.002 |
강황추출물 | 84775-52-0 | 0.001 | X | 0.001 | 0.0005 | 0.002 | 0.004 | 0.001 |
마치현추출물 | 90083-07-1 | 0.001 | 0.001 | X | 0.001 | 0.001 | 0.001 | 0.001 |
위치하젤수 |
CFTA ID | 0.001 |
0.001 |
X |
0.001 |
0.001 |
0.001 |
0.001 |
9415 | ||||||||
셀러리추출물 | CFTA ID: | 0.0001 | 0.0001 | X | 0.0001 | 0.0001 | 0.0001 | 0.0001 |
양배추잎추출물 | 89958-13-4 | 0.0001 | 0.0001 | X | 0.0001 | 0.0001 | 0.0001 | 0.0001 |
기타 조성물 |
6.16 | 6.16 | 6.16 | 6.16 | 6.16 | 6.16 | 6.16 | |
Total | 100 | 100 | 100 | 100 | 100 | 100 | 100 |
시험물질 | 주관적 자극 (따끔거림, 가려움) |
객관적 자극 (홍반, 부종) |
합계 |
비교예1 | 15 | 16 | 31 |
비교예2 | 17 | 16 | 33 |
비교예3 | 15 | 16 | 31 |
비교예4 | 14 | 15 | 29 |
비교예5 | 16 | 14 | 30 |
비교예6 | 15 | 15 | 30 |
비교예7 | 18 | 17 | 35 |
비교예8 | 17 | 17 | 34 |
비교예9 | 18 | 18 | 36 |
비교예10 | 19 | 18 | 37 |
실험예1 | 16 | 14 | 30 |
실험예2 | 14 | 15 | 29 |
실험예3 | 10 | 11 | 21 |
실험예4 | 12 | 10 | 22 |
5% 락틱산 | 30 | 25 | 55 |
시료 재질 | 시료 제원(가로x세로x두께) |
아크릴 섬유 | 50mm X 50mm X 5.00mm |
나일론 섬유 | 50mm X 50mm X 2.32mm |
폴리에틸렌 필름 | 50mm X 50mm X 0.22mm |
카페트 | 50mm X 50mm X 1.68mm |
스폰지 | 50mm X 50mm X 5.21mm |
고무판 | 50mm X 50mm X 0.06mm |
시 료 | 아크릴섬유 | 나일론섬유 | 폴리에틸렌섬유 | 카페트 | 스폰지 | 고무판 | |
대조군 | ∞ | ∞ | ∞ | ∞ | ∞ | ∞ | |
탈이온 증류수에 폴리소르베이트80 5% 첨가용액 처리 |
30.1 | 12.3 | 12.2 | 0.3 | 0.8 | 14.2 | |
비교예1 | 2.50 | 0.80 | 0.5 | 0.28 | 0.60 | 1.20 | |
비교예2 | 2.20 | 0.60 | 0.53 | 0.27 | 0.63 | 1.10 | |
비교예3 | 2.40 | 0.50 | 0.57 | 0.28 | 0.65 | 1.25 | |
비교예4 | 2.60 | 0.55 | 0.55 | 0.26 | 0.60 | 1.30 | |
비교예5 | 2.35 | 0.50 | 0.60 | 0.25 | 0.68 | 1.32 | |
비교예6 | 3.00 | 0.60 | 0.55 | 0.26 | 0.65 | 1.40 | |
비교예7 | 3.00 | 0.70 | 0.57 | 0.30 | 0.80 | 1.70 | |
비교예8 | 3.00 | 0.74 | 0.58 | 0.32 | 0.82 | 1.80 | |
비교예9 | 3.00 | 0.72 | 0.63 | 0.33 | 0.84 | 1.84 | |
비교예10 | 3.00 | 0.75 | 0.61 | 0.32 | 0.81 | 1.78 | |
실험예1 | 0.9 | 0.4 | 0.32 | 0.27 | 0.59 | 1.25 | |
실험예2 | 0.8 | 0.35 | 0.3 | 0.28 | 0.62 | 1.3 | |
실험예3 | 0.1 | 0.1 | 0.1 | 0.1 | 0.52 | 0.5 | |
실험예4 | 0.0 |
0.0 |
0.1 | 0.2 | 0.50 |
0.4 |
Claims (8)
- 전체 중량을 기준으로 악마의발톱뿌리 추출물 0.5~1.5중량부, 병풀추출물 0.4~0.6중량부, 달팽이점액여과물 0.03~0.07중량부 및 양배추잎추출물 0.00005~0.00015중량부를 포함하는 피부 진정 및 통전용 화장료 조성물.
- 제 1항에 있어서,
양파추출물 0.005~0.015중량부, 강황추출물 0.0005~0.0015중량부, 마치현추출물 0.0005~0.0015중량부, 셀러리추출물 0.00005~0.00015중량부, 위치하젤수 0.0005~0.0015중량부 및 프롤린 0.001~0.003중량부를 추가로 첨가하는 것을 특징으로 하는 피부 진정 및 통전용 화장료 조성물.
- 제 1항 또는 제 2항에 있어서,
전체 조성물의 중량을 기준으로 디메치콘 0.5~1.5중량부, 부틸렌글라이콜 3.0~7.0중량부 및 글리세린 3.0~7.0중량부를 추가로 첨가하는 것을 특징으로 하는 피부 진정 및 통전용 화장료 조성물.
- 전체 조성물의 중량을 기준으로 악마의발톱뿌리추출물 1.0중량부, 병풀추출물 0.5중량부, 달팽이점액여과물 0.05중량부, 양배추잎추출물 0.0001중량부, 양파추출물 0.01중량부, 강황추출물 0.001중량부, 마치현추출물 0.001중량부, 셀러리추출물 0.0001중량부, 위치하젤수 0.001중량부, 프롤린 0.002중량부, 디메치콘 1.0중량부, 부틸렌글라이콜 5.0중량부 및 글리세린 5.0중량부를 포함하는 피부 진정 및 통전용 화장료 조성물.
- 전체 중량을 기준으로 악마의발톱뿌리 추출물 0.5~1.5중량부, 병풀추출물 0.4~0.6중량부, 달팽이점액여과물 0.03~0.07중량부 및 양배추잎추출물 0.00005~0.00015중량부를 혼합하는 단계를 포함하는 피부 진정 및 통전용 화장료 조성물의 제조 방법.
- 제 5항에 있어서,
양파추출물 0.005~0.015중량부, 강황추출물 0.0005~0.0015중량부, 마치현추출물 0.0005~0.0015중량부, 셀러리추출물 0.00005~0.00015중량부, 위치하젤수 0.0005~0.0015중량부 및 프롤린 0.001~0.003중량부를 추가로 혼합하는 단계를 포함하는 것을 특징으로 하는 피부 진정 및 통전용 화장료 조성물의 제조 방법.
- 제 5항 또는 제 6항에 있어서,
전체 조성물의 중량을 기준으로 디메치콘 0.5~1.5중량부, 부틸렌글라이콜 3.0~7.0중량부 및 글리세린 3.0~7.0중량부를 추가로 혼합하는 단계를 포함하는 것을 특징으로 하는 피부 진정 및 통전용 화장료 조성물의 제조 방법.
- 전체 조성물의 중량을 기준으로 악마의발톱뿌리추출물 1.0중량부, 병풀추출물 0.5중량부, 달팽이점액여과물 0.05중량부, 양배추잎추출물 0.0001중량부, 양파추출물 0.01중량부, 강황추출물 0.001중량부, 마치현추출물 0.001중량부, 셀러리추출물 0.0001중량부, 위치하젤수 0.001중량부, 프롤린 0.002중량부, 디메치콘 1.0중량부, 부틸렌글라이콜 5.0중량부 및 글리세린 5.0 중량부를 혼합하는 단계를 포함하는 피부 진정 및 통전용 화장료 조성물의 제조 방법.
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