KR101128279B1 - Biomedical data measuring device, method for determining error on physiological data measuring device, storage medium recording program therein - Google Patents

Abstract

The present invention results from an error in the device (Sun Error) due to the device being overexposed to external light and from the measurement strip being not properly attached to the device or the measurement strip being removed during device operation. The present invention relates to a biological data measuring apparatus capable of quickly recognizing an error of a device (strip removal error) and clearly classifying the type of the error, and a method of determining the error of the device and a program of the method.
According to one aspect of the present invention, there is provided a biometric data measuring apparatus, in which a measurement strip is inserted to measure biometric data of a biological sample, wherein the light reflected from a corresponding area on the measurement strip is detected and the amount of light detected therefrom. A detector for converting the digital signal into a digitized electric signal; And a data processor for calculating biometric data based on the electric signal value transmitted from the sensor, wherein the data processor comprises: K / S (a) = (1-R _∞ ) ² / 2R _∞ (where R _∞ = Digit _{t = a} / Digit _{t = 0} , Digit _{t = a} is the light quantity value measured by the detector at time t = a, Digit _{t = 0} is the light quantity value measured by the sensor at time t = 0, K : Absorption coefficient, S: Scattering coefficient, R: The biometric data is calculated according to the K / S value according to the formula of the spectral reflectance measured by the detection unit, and the K / S value is calculated from the biological sample itself. It is determined whether or not the abnormal number is an abnormal number, and whether or not the abnormal value is a value maintained for a predetermined time or more, which is determined according to the type of the substance to be analyzed in the biological sample, and the K / S value is determined in advance. In case of abnormal value maintained for a fixed time or more It is determined that the measurement strip is removed from the main body of the device, and if the external light of more than the measurable range is introduced into the sensing unit, it is determined that it is a sun error (sun error), characterized in that to provide.

Description

Biometric data measuring device, error determination method of biometric data measuring device and recording medium recording program thereof

The present invention relates to a biological data measuring apparatus, a method for determining an error of a biological data measuring apparatus, and a recording medium on which a program of the method is recorded. More particularly, the present invention relates to an apparatus error due to excessive exposure to external light. Hereinafter referred to as "Sun Error" and errors in the device (hereinafter referred to as "strip removal error") resulting from the measurement strip not being properly fitted to the device or the measurement strip being removed during operation of the device. The present invention relates to a biometric data measuring apparatus capable of quickly recognizing the error and clearly classifying the type of the error, and to a method of determining the error of the apparatus and a recording medium recording the program of the method.

As is well known, the biometric data measuring device is a device for measuring biometric data such as cholesterol and blood sugar by analyzing a sample such as blood.

In general, the biometric data measuring apparatus includes a measuring strip having a structure of a device body and a structure detachable from the apparatus body. For example, the measurement strip includes a reaction zone containing a reaction enzyme capable of reacting with a sample such as blood to measure cholesterol, blood sugar, and the like, and each functional unit of the apparatus main body has a reaction result in the reaction zone of the measurement strip. It detects and analyzes the biometric data.

Since such a biometric data measuring device is a device for detecting and analyzing data related to human life, device reliability is very important.

Therefore, external factors (eg strong sunlight) of the device act in the reaction zone of the measuring strip, making the biodata unreliable, or the measuring strip is not correctly mounted in the device body (or the measuring strip during the execution of the device). If the biometric data is unreliable, it is very important to detect it quickly and treat it as an error.

In addition, since the user needs to know the type of the device error correctly so that the user can take an action corresponding to the error, it is also very important to accurately determine the type of the error as well as to quickly detect the device error. For example, if an error occurs due to the biodata measuring device being exposed to strong external light, and the measurement strip is recognized as detached from the device body and the result is displayed to the user, the user may make an error. It is necessary to confuse the cause and take unnecessary countermeasures (e.g., recheck the position of the measurement strip), which acts as a large factor to lower the reliability of the apparatus.

On the other hand, in recent years, in order to lower the error rate due to external factors of the device, ie, strong sunlight, etc., a biometric data measuring device having a separate cover installed at a portion where a measurement strip is mounted has been proposed. However, even if a separate cover is installed at the site where the strip of the biodata measuring device is mounted, there are still factors that may cause an error, and in operating such a cover-mounted measuring device, an open (coverless type) measuring device. Usability is significantly reduced compared to the case of operating (e.g., the usability is significantly reduced since the preliminary operation of opening (or closing) the cover before (or after) mounting the measuring strip to the main body) is also inferior. Since there is a problem in that the device cost increases due to the additional installation of the, there is a need for a fundamental solution that can solve the above-mentioned problems without installing a separate cover in the site where the strip is mounted.

The present invention has been conceived in view of the above-described problems, and it is possible to quickly recognize an error of the biometric data measuring device, and also to clarify the type of the error (for example, "Sun error" or "strip removal error"). An object of the present invention is to provide a discernible biometric data measuring apparatus, an error determination method of the biometric data measuring apparatus, and a recording medium on which a program of the method is recorded.

In order to achieve the first object of the above-described invention, a preferred embodiment of the present invention is a biometric data measuring device in which a measurement strip is inserted to measure biometric data of a biological sample.

A detector for detecting light reflected from a corresponding area on the measurement strip and converting the light amount of the detected light into a digitized electric signal value;

And a data processor configured to calculate biometric data based on the electric signal value transmitted from the detector, wherein the data processor comprises:

K / S (a) = (1-R _∞ ) ² / 2R _∞ (where R _∞ = Digit _{t = a} / Digit _{t = 0} and Digit _{t = a} is the amount of light measured by the detector at time t = a) Value, Digit _{t = 0} according to the K / S value according to the formula of the light quantity value measured by the detector at time t = 0, K: extinction coefficient, S: scattering coefficient, R: spectral reflectance measured by the detector Calculating the biometric data,

It is determined whether the K / S value is an abnormal value that cannot be calculated from the biological sample itself,

It is determined whether the abnormal value is a value maintained for a predetermined time or more, which is determined according to the type of substance to be analyzed in the biological sample,

Determining that the measuring strip has been removed from the apparatus main body when the K / S value is an abnormal value maintained over the predetermined predetermined time,
According to an aspect of the present disclosure, there is provided a biometric data measuring apparatus, which performs an operation of determining a sun error when external light having a measurable range is introduced into the sensing unit.

In addition, another preferred embodiment of the present invention, in order to achieve the above-mentioned second object of the present invention, detects the light reflected from the corresponding area on the measurement strip inserted in the measuring device main body and the digitized electric signal An error determination method of a biological data measuring apparatus including a detector converting a value into a value, and a data processor calculating a biometric data based on the electric signal value transmitted from the detector.

(a) K / S (a) = (1-R _∞ ) ² / 2R _∞ (where R _∞ = Digit _{t = a} / Digit _{t = 0} , and Digit _{t = a} is the detector at time t = a The measured light quantity value, Digit _{t = 0} is the light quantity value measured by the detector at time t = 0, K: the extinction coefficient, S: scattering coefficient, R: the spectral reflectance measured by the detector; Calculating a K / S value for the calculation;

(b) determining whether the K / S value is an abnormal value that cannot be calculated from the biological sample itself;

(c) determining whether the abnormal value is a value maintained for a predetermined time or more determined according to the type of the substance to be analyzed in the biological sample;

(d) determining that the measurement strip has been removed from the apparatus main body when it is determined that the K / S value is an abnormal value maintained over the predetermined predetermined time; And
(e) when calculating the K / S value in step (a), if it is determined that the value of Digit _{t = a} exceeds a measurable range of the sensing unit, determining it as a sun error An error determination method of a biometric data measuring apparatus is provided.

In addition, another preferred embodiment of the present invention for achieving the above-mentioned third object of the present invention is to detect the light reflected from the corresponding area on the measuring strip inserted in the measuring device main body and to digitize the light quantity of the detected light. A computer-readable recording recording a program for performing an error determination method of a biometric data measuring device, comprising a sensing unit converting the signal value to a signal value, and a data processing unit calculating a biometric data based on the electric signal value transmitted from the sensing unit. As a medium, the method,

(a) K / S (a) = (1-R _∞ ) ² / 2R _∞ (where R _∞ = Digit _{t = a} / Digit _{t = 0} , and Digit _{t = a} is the detector at time t = a The measured light quantity value, Digit _{t = 0} is the light quantity value measured by the detector at time t = 0, K: the extinction coefficient, S: scattering coefficient, R: the spectral reflectance measured by the detector; Calculating a K / S value for the calculation;

(b) determining whether the K / S value is an abnormal value that cannot be calculated from the biological sample itself;

(c) determining whether the abnormal value is a value maintained for a predetermined time or more determined according to the type of the substance to be analyzed in the biological sample;

(d) determining that the measurement strip has been removed from the apparatus main body when it is determined that the K / S value is an abnormal value maintained over the predetermined predetermined time; And
(e) when calculating the K / S value in step (a), if it is determined that the value of Digit _{t = a} exceeds a measurable range of the sensing unit, determining it as a sun error A computer readable recording medium is provided.

1 is a schematic view showing the appearance of a biometric data measuring device and a measuring strip according to a preferred embodiment of the present invention.
2 is an exploded perspective view for explaining the detailed structure of the measuring strip of FIG.
Figure 3 is a block diagram for explaining each functional unit of the biometric data measuring apparatus according to an embodiment of the present invention.
4A and 4B are graphs showing test results when the biometric data measuring apparatus calculates a K / S value.
FIG. 5 is a graph for explaining a phenomenon when external light having a measurable range is introduced when the biometric data measuring apparatus calculates a K / S value. FIG.
FIG. 6 is a graph for explaining a phenomenon when the measurement strip is removed from the main body of the device while the biometric data measuring device is calculating the K / S value. FIG.
7 is a flow chart for explaining in detail the biometric data measurement and error determination operation of the biometric data measuring apparatus 100 according to an embodiment of the present invention.

1 is a schematic view showing the appearance of a biometric data measuring apparatus and a measuring strip according to a preferred embodiment of the present invention, Figure 2 is an exploded perspective view for explaining the detailed structure of the measuring strip of FIG.

First, referring to FIG. 1, the biometric data measuring apparatus 100 includes a display unit 130, a power button 140, and a strip insertion region 150.

The strip insertion region 150 is a portion where the measurement strip 200 is mounted. In addition, a plurality of sensing units 110-1, 110-2, and 110-3 are spaced apart from each other at the center of the strip insertion region 150. The plurality of sensing units 110-1, 110-2, and 110-3 correspond one-to-one with each reaction unit 230 of the measuring strip 200, and all or part of the sensing units 110-1 is activated depending on the type of measurement. The reaction result of the unit 230 is sensed.

The measuring strip 200 has a structure detachable from the main body (specifically, the strip insertion region 150) of the measuring device 100. Referring to the structure of the measurement strip 200 in more detail with reference to Figure 2, the measurement strip 200 is made of a structure in which the upper support 210 and the lower support 220 is combined, the upper support 210 Between the and the lower support 220 is interposed the reaction unit 230 of the form in which the reaction enzyme is coupled to the paper. Holes 210-1, 210-2, and 210-3 exposing the reaction part so as to attempt a biological reaction by adding a sample such as blood to the upper part of the upper support part 210 with the reaction part 230 are provided. Formed. In addition, holes 220-1, 220-2, and 220-3 are formed in the lower supporter 220 so that the sensing unit 110 detects a reaction result of the reaction unit 230.

3 is a block diagram illustrating each functional unit of a biometric data measuring apparatus according to an exemplary embodiment of the present invention.

Referring to the block diagram of FIG. 3, the biometric data measuring apparatus 100 according to an exemplary embodiment of the present invention includes a sensing unit 110, a data processing unit 120, and a display unit 130.

The detector 110 detects an area on the measurement strip 200 corresponding to the detector 110. According to a preferred embodiment, the sensing unit 110 may be configured in plural in order to measure one or more biometric data. For example, the first sensing unit 110-1 and the second sensing unit 110-2 are illustrated in FIG. 3. And the sensing unit 110 by the third sensing unit 110-3.

For example, the sensing unit 110 may be implemented by measuring reflectivity of an area on a measurement strip corresponding to the sensing unit 110. The sensing unit 110 may emit light (not shown) that emits light and light emitted from the emitting unit. It may be implemented to include a light receiving unit (not shown) for receiving and sensing. According to a preferred embodiment, the light emitting unit (not shown) of the sensing unit 110 may be composed of an LED (LED) for generating light and a driving circuit, the light receiving unit (not shown) is a photodiode and analog absorbing light It may be implemented in a form including a digital converter. Hereinafter, in the present exemplary embodiment, the light emitting unit of the sensing unit 110 includes an LED and a driving circuit, and the light receiving unit of the sensing unit 110 includes a photo diode.

The detector 110 receives the light reflected from the corresponding area on the measurement strip 200, converts the light amount of the received light into a digitized electric signal value, and transmits the light to the data processor 120 as the detection result data.

The strip insertion detection unit 121 configuring the data processing unit 120 determines the detection result data transmitted from the detection unit 110, so that the amount of light received by the detection unit 110 is greater than or equal to a predetermined range, for example. If 1000 digit or more (where the resolution of the digit depends on the performance of the data processing unit 120), it is determined that the measurement strip 200 is properly mounted.

According to a preferred embodiment, the strip insertion detector 121 is a range of the amount of light that can be received when the reaction unit 230 of the measurement strip 200 is located in the area corresponding to the detection unit 110 (for example , 1000 digits in advance, and if the received light amount in the detection result data transmitted from the sensing unit 110 is equal to or greater than the amount of light that can be received, the measurement strip 200 may be configured to be properly installed.

The biometric data measuring unit 122 constituting the data processing unit 120 configures blood based on the amount of light received based on the detection result data (the amount of light received by the detecting unit 110) transmitted from the detecting unit 110. By converting the concentration into a concentration value of serum or the like, biological data of each reaction unit 230 corresponding to the detection unit 110, for example, total cholesterol, HDL-cholesterol, triglycerides, blood sugar, and the like are determined.

In one embodiment, the biometric data measuring unit 122 calculates the K / S value by the following Equation 1 (Kubelka-Munk equation), and the amount of light received by the detection unit is determined by a concentration value such as serum. Can be converted to Here, the K / S value is proportional to the concentration of serum or the like.

[Equation 1]

K / S (a) = (1-R _∞ ) ² / 2R _∞

Where R _∞ = Digit _{t = a} / Digit _{t = 0} , Digit _{t = a} is the light quantity measured by the detector at t = a, and Digit _{t = 0} is the light quantity measured by the detector at t = 0 , K: extinction coefficient, S: scattering coefficient, R: spectral reflectance measured by detector

Meanwhile, the K / S value of Equation 1 is calculated based on a case in which the photodiode constituting the sensing unit 110 receives only the light (light reflected by the reaction unit 230) generated from the LED. Although it is a calculation formula regarding the density | concentration value of serum etc., in fact, not only light from an LED but external light (for example, the sunlight irradiated directly to a photodiode) enters into the photodiode of the detection part 110.

Therefore, in order to convert the amount of light received by the photodiode of the sensing unit 100 into a concentration value such as serum according to Equation 1, the amount of light due to external light is deleted from the amount of light received by the photodiode. It is necessary to perform the correction.

In one embodiment, the biometric data measuring unit 122 performs the correction to remove the light amount value due to the external light from the light amount value of the light received by the photodiode by the correction method of Equation 2 below.

[Equation 2]

Digit _{t = a} = Digit (origin) _{t = a} -Digit (extra) _{t = a}

Where Digit _{t = a} is the quantity of light measured by the photodiode at t = a, Digit (origin) _{t = a} is the quantity of light measured by the photodiode in the LED-on state at t = a, Digit (extra) _{t = a} is the amount of light measured by the photodiode in the LED off state at the time t = a)

However, Equation 2 assumes that the photodiode simultaneously measures the Digit values of the LED ON state and the OFF state at the same time, so that the biometric data measuring apparatus 100 completely applies the correction method according to Equation 2 above. In theory, each pair of LEDs and photodiodes is required.

Meanwhile, in applying the sensing unit 110 to the actual biometric data measuring apparatus 100, it is most preferable to configure the sensing unit 110 with one LED and one photodiode in terms of miniaturization and manufacturing cost of the apparatus. .

Therefore, in order to configure the sensing unit 110 as one LED and a photo diode, respectively, Equation 3 below may be applied instead of Equation 2.

[Equation 3]

Digit _{t = a} = Digit (origin) _{t = a1} -Digit (extra) _{t = a2}

Where Digit _{t = a} is the quantity of light measured by the photodiode at t = a, Digit (origin) _{t = a1} is the quantity of light measured by the photodiode in the LED on state at t = a1, Digit (extra) _{t = a2} is the amount of light measured by the photodiode in the LED off state at t = a2, t = a ≒ a1 ≒ a2)

At this time, if the on / off interval of the LED is applied to about 100 milliseconds (ms), t = a ≒ a1 ≒ a2, and the sensing unit 110 composed of one LED and a photodiode respectively, The same correction effect can be expressed.

4A and 4B illustrate a case where the biometric data measuring unit 122 calculates the K / S value by the above-described [Equation 1] (Kubelka-Munk equation) using the above-described correction method according to [Equation 3]. A graph showing the test results. 4A and 4B show the results of operating the biometric data measuring apparatus indoors and outdoors, respectively, and the horizontal axis of the figure represents measurement time, and the vertical axis represents K / S value and intensity of external light.

As can be seen from FIG. 4A, when the biodata measuring apparatus 100 is operated in a room where the external light amount is small or constant, the change in the K / S value calculated by the biodata measuring unit 122 is very gentle or It can be seen that there is little. That is, despite the external light by the indoor lighting system, the biometric data measuring unit 122 can calculate the highly reliable biometric data according to [Equation 1] and [Equation 3] described above.

On the other hand, as can be seen from Figure 4b, when operating the biometric data measuring apparatus 100 in the outdoor where the amount of external light is large or sudden change, the K / S value calculated by the biometric data measuring unit 122 It can be seen from the graph that a peak with a very steep slope appears instantaneously. These peaks indicate that a sudden external light quantity change occurs during the time difference (around 100 milliseconds (ms)) of a2-a1 when the biodata measuring unit 122 applies the correction method according to [Equation 3] described above. .

That is, in an environment in which the amount of external light changes rapidly due to direct exposure to outdoor sunlight, etc., the biometric data measuring unit 122 includes biometric data of some unreliable sections (sections in which peaks of very steep slopes appear). As you can, you need a process to determine whether to treat this as an error. As will be described later, in the present invention, the error determining unit 123 processes such a process.

Meanwhile, FIG. 5 illustrates that the biodata measuring unit 122 calculates the K / S value by the above-described [Equation 1] (Kubelka-Munk equation) using the correction method according to [Equation 3] described above. This is a graph for explaining the phenomenon when the amount of light beyond the measurable area is introduced into the diode. Here, the graph indicated by the dotted line of FIG. 5 is a digit (origin) value (ie, a LED diode in the LED-on state) when external light (for example, sunlight) of each size is incident on the biometric data measuring apparatus 100. 5 represents the amount of light measured, and the graph represented by the solid line in FIG. ).

When the amount of light incident from the external light is abnormally large, light above the measurement range may be introduced into the photodiode. Referring to the dotted line graph of FIG. 5, the digit (origin) value (that is, the light quantity value due to the sum of external light and LED light) when the biometric data measuring unit 122 applies the correction method according to [Equation 3] described above. ) No longer increases in the range where the photodiode is measurable (near 4000 digit in FIG. 5).

At this time, when the Digit (extra) value (that is, the measured light quantity value only by external light) continues to increase, the Digit _{t = a} value according to [Equation 3] described above (that is, the light quantity value by pure LED only). Rather, it gradually decreases. In this case, since the light quantity value by the LED is not decreasing at all, an error occurs between the digit _{t = a} value calculated by the biometric data measuring unit 122 and the actual value.

Therefore, when a situation in which light beyond the measurement range is introduced into the photodiode occurs, the biometric data measuring unit 122 may calculate some unreliable biometric data, and thus, a process of treating it as an error (sun error) is necessary. . As will be described later, in the present invention, the error determining unit 123 processes such a process.

The error determining unit 123 constituting the data processing unit 120 uses the above-described [Equation 1] (Kubelka-Munk equation) using the correction method according to [Equation 3] described above. Monitor whether the source of error intervenes while calculating the K / S value. In addition, the error determining unit 123 terminates the procedure executed by the biometric data measuring unit 122 when the cause of the error is involved, and outputs the result to the display unit.

According to a preferred embodiment, the error determination unit 123 recognizes this as a "sun error" when light in the photodiode is introduced into the photodiode, terminates the procedure performed by the biodata measuring unit 122, and as a result, Is output to the display unit 130. For example, when more than 4000 digits of light is introduced into the photodiode, the error determining unit 123 recognizes this as a "sun error" and outputs the result to the display unit 130.

In addition, the error determining unit 123 recognizes this as a "strip removal error" when the measuring strip 200 is not properly attached to the apparatus 100 or when the measuring strip is detached during the operation of the apparatus, and the biometric data measuring unit ( After the procedure 122 executes, the result is output to the display unit 130.

The "strip removal error" processing operation of the error determining unit 123 will be described in more detail below with reference to FIGS. 6 and 7.

FIG. 6 shows a measurement strip (b) while the biometric data measuring unit 122 calculates the K / S value by the above-described [Equation 1] (Kubelka-Munk equation) using the above-described correction method according to [Equation 3]. 200 is a graph for explaining a phenomenon when the body is detached from the main body of the biometric data measuring apparatus 100.

The pattern 1 is the external light when the biometric data measuring unit 122 calculates the K / S value by the above-described [Equation 1] (Kubelka-Munk equation) using the above-described correction method according to [Equation 3]. It shows the change of K / S value according to the change.

In addition, the pattern 2 is roughly calculated while the biometric data measuring unit 122 calculates the K / S value by the above-described [Equation 1] (Kubelka-Munk equation) using the above-described correction method according to [Equation 3]. When the measurement strip 200 is detached from the main body of the biometric data measuring apparatus 100 at about 100 sec, the change in the K / S value according to the external light change is shown.

As can be seen from FIG. 6, in the pattern 1, a very steeply inclined peak appears instantaneously at the point where the external light changes rapidly (about 100 sec), but as the rapidly changing external light remains constant, It can be seen that the phenomenon of returning to the data pattern occurs again.

However, in pattern 2, the measurement strip 200 is detached from the main body of the biometric data measuring apparatus 100 at about 100 sec, and the K / S value is jumped higher than the actual value, and the jumped K / S value is the original. It can be seen that a phenomenon that does not return to the pattern occurs again.

The significant difference as described above between the pattern 1 and the pattern 2 is due to the following causes.

First, in the case of pattern 1, as the biometric data measuring unit 122 uses the correction method according to [Equation 3] described above, Digit _{t = a} = Digit (origin) _{t = a1} -Digit (extra) _{t = a2} The value of Digit _{t = a} changed momentarily at the point where a sudden external light change occurred during the time difference (around 100 milliseconds (ms)) between a1 (ie, the LED on state) and a2 (ie, the LED off state). The peak of steepness is very steep), and in the case of maintaining the final state where the rapidly changing external light changes for a certain time, the value of Digit _{t = a is the} value of the external light regardless of the magnitude of the change of the external light. Return to the value before the sudden change.

However, in the case of the pattern 2, as the measurement strip 200 is detached from the main body of the apparatus 100, since the external light amount changes and the light amount by the LED also changes, Digit _{t = a} = Digit (origin) _{t = The} Digit _{t = a} value at _a1 -Digit (extra) _{t = a2} is jumped higher than a certain value from the moment the measuring strip 200 is detached, and then the measuring strip 200 is returned to the main body of the apparatus 100 again. The pattern of the jumped state (hereinafter referred to as a "staircase pattern") is maintained until it is mounted (a pattern that jumps higher than a predetermined value and then does not return to the state before jumping).

Next, referring again to FIG. 3 and FIG. 6, the error determining unit 123 determines the "strip removal error" by recognizing the stepped pattern shown in the pattern 2 of FIG. 6.

According to a preferred embodiment, in order to recognize the stepped pattern of FIG. 6, the error determining unit 123 cannot recognize the K / S value at a specific time point from a normal biological sample (eg, serum) itself. First, it is determined whether it is an abnormal value, and when the K / S value is an abnormal value, it is determined whether or not the value is a value held for more than a predetermined predetermined time.

According to a preferred embodiment, the error determining unit 123 may determine that the K / S value calculated by the biometric data measuring unit 122 is an abnormal value when K / S> 2.5.

In addition, according to a preferred embodiment, the error determination unit 123 includes data relating to the above-described "predetermined predetermined time". For example, the above-mentioned "predetermined predetermined time" may be a value determined differently according to the substance (eg, high density lipoprotein, triglyceride, total cholesterol, etc.) to be analyzed in the biological sample.

For example, if the substance to be analyzed in the biological sample is a high density lipoprotein (HDL), the error determining unit 123 has a K / S value of K / S> 2.5 and the K / S value of the material. If it is determined that it has been held for 1 second or more, it can finally be determined as "strip removal error". In addition, the error determining unit 123, when the substance to be analyzed in the biological sample is triglyceride (TG) or total cholesterol (TC: Total Cholesterol), the K / S value is K / S> 2.5 and the K If it is determined that the value / S is maintained for 5 seconds or more, it can finally be determined as "strip removal error".

As another embodiment in which the error determining unit 123 recognizes the stepped pattern of FIG. 6 to determine the "strip removal error", it is determined whether the K / S value at a specific time point is an abnormal value that cannot be observed from the normal biological sample itself. First, if the K / S value is an abnormal value, it is determined whether the value has been maintained for more than a predetermined predetermined time, and finally if the value has been maintained for more than a predetermined predetermined time. One may consider how to determine whether a consistent value has been maintained for that " predetermined constant time. &Quot; For example, if the substance to be analyzed in the biological sample is triglyceride (TG), the error determining unit 123 has a K / S value of K / S> 2.5 and the K / S value of 5 seconds or more. If it is determined that the value has been held and the value while being held for more than 5 seconds is determined not to be variable, it can finally be determined as "strip removal error".

According to a preferred embodiment, the biometric data measuring unit 122 and the error determining unit 123 are programmed to perform biometric data using the above-described K / S value and its error determination operation (hereinafter referred to as "biodata measuring and Each component of the "error determination program". In addition, the biometric data measurement and error determination program according to an embodiment of the present invention is a computer-readable flexible disk, CD-R, DVD-RW, DVD-RAM, magneto-optical disk, all or part of the program, It may be stored in a streamer, a hard disk, a memory, or another recording medium.

FIG. 7 is a flow chart for explaining in detail the biometric data measurement and error determination operation of the biometric data measuring apparatus 100 according to an embodiment of the present invention.

First, the biometric data measuring apparatus 100 determines that the measuring strip 200 is properly mounted when the amount of light received by the sensing unit 110 is greater than or equal to a predetermined range, for example, 1000 digit (S701 and S702). .

Next, the biometric data measuring apparatus 100 calculates a Digit (Digit (origin) -Digit (extra)) value D1 of the measurement strip 200 using the correction method according to [Equation 3] (S703) ( At this time, if the Digit value is 4000 or more, it is recognized as a Sun error error, the procedure is terminated, and the result is output to the display unit (S705 and S707).

Next, the biological data measuring apparatus 100 determines whether the blood injection waiting time has elapsed a predetermined time (for example, 3 minutes) (S709), and when the blood injection waiting time has not elapsed, a predetermined short waiting time. After the elapse of time (for example, one second) (S711), the Digit value D2 of the measurement strip 200 is calculated again (S713). After completion, the result is displayed on the display unit (S715, S717).

Next, the biometric data measuring apparatus 100 determines whether blood is injected into the measurement strip 200 by determining whether the value D1-D2 is greater than or equal to a predetermined value, for example, whether D1-D2> 200 ( S719).

Next, when it is determined that the blood is injected into the measurement strip 200 in step S719, the biometric data measuring apparatus 100 calculates the digit value D3 of the measurement strip 200 (S721) (at this time, If the Digit value is 4000 or more, it is recognized as a Sun error error and the procedure is terminated, and the result is displayed on the display unit (S723, S725), and the measurement strip 200 is again present at a certain time elapsed (for example, after 5 seconds). (S727, S729) (At this time, if the Digit value is 4000 or more, it is recognized as a Sun error error and the procedure is terminated, and the result is displayed on the display unit (S731, S732).) .

Next, the biometric data measuring apparatus 100 calculates the K / S (3) by the digit value D3 calculated in step S721 and the K / S (4) by the digit value D4 calculated in the step S729. Each operation is performed (S733). Here, K / S (3) and K / S (4) are K / S (3) = (1-R ₃ ) ² / 2R ₃ (where R ₃ = D3), respectively, according to Equation 1 described above. / D1), K / S (4) = (1-R ₄ ) ² / 2R ₄ , where R ₄ = D4 / D1.

Next, the biometric data measuring apparatus 100 determines whether the K / S (4) value exceeds 2.5 (S735). That is, the biometric data measuring apparatus 100 determines that the K / S (4) value is an abnormal value that cannot be observed in a sample such as serum when the K / S (4) value exceeds 2.5.

Next, if it is determined in step S735 that K / S (4)> 2.5, the biometric data measuring apparatus 100 determines whether the K / S (3) value exceeds 2.5 (S737). That is, when the K / S (3) value also exceeds 2.5, the biometric data measuring apparatus 100 determines that the abnormal value of the K / S (4) has lasted for 5 seconds or longer and finally results in a "strip removal error". After the determination, the procedure is terminated.

On the other hand, although not shown in Figure 7, the biometric data measuring apparatus 100 further performs an operation of determining whether or not the condition of K / S (4) = K / S (3) after the step S737 "strip" The judgment rate of "removal error" can be further increased. For example, the biometric data measuring apparatus 100 may be configured to finally determine a "strip removal error" only when the condition of K / S (4) = K / S (3) is satisfied. If the condition of K / S (4) = K / S (3) is satisfied, the value of K / S (4) (abnormal numerical value) is guaranteed to be maintained for the same value for 5 seconds or more. The probability of working is significantly higher.

On the other hand, when the K / S 4 exceeds 2.5, the biometric data measuring apparatus 100 does not exceed 2.5, the current K / S 4 value is the external light. It is determined that this is a temporary abnormal value by, for example, and returns to step S727 again.

Next, the biometric data measuring apparatus 100 repeats the steps S727 to S735 until the set measuring time has elapsed, and then the value of the K / S (4) does not exceed 2.5 (that is, the normal value). The K / S (4) value is determined as the final value (S740 to S743).

Finally, the biometric data measuring apparatus 100 converts the K / S 4 determined as the final value into biometric data and outputs it to the display unit 130 (S745).

Accordingly, the user can be provided with highly reliable biometric data in which error factors are completely eliminated.

100: biometric data measuring device 110: detector
120: data processing unit 121: strip insertion detection unit
122: biometric data measuring unit 123: error determination unit
130: display unit 140: power button
150: strip insertion area 200: measuring strip
210: upper support 220: lower support
230: reaction part

Claims (22)

In the biometric data measuring apparatus for inserting a measuring strip to measure the biometric data of the biological sample,
A detector for detecting light reflected from a corresponding area on the measurement strip and converting the light amount of the detected light into a digitized electric signal value;
And a data processor configured to calculate biometric data based on the electric signal value transmitted from the detector, wherein the data processor comprises:
K / S (a) = (1-R _∞ ) ² / 2R _∞ (where R _∞ = Digit _{t = a} / Digit _{t = 0} , Digit _{t = a} is the amount of light measured by the detector at time t = a) Value, Digit _{t = 0} according to the K / S value according to the formula of the light quantity value measured by the detector at time t = 0, K: extinction coefficient, S: scattering coefficient, R: spectral reflectance measured by the detector) Calculating the biometric data,
It is determined whether the K / S value is an abnormal value that cannot be calculated from the biological sample itself,
It is determined whether the abnormal value is a value maintained for a predetermined time or more, which is determined according to the type of substance to be analyzed in the biological sample,
Determining that the measuring strip has been removed from the apparatus main body when the K / S value is an abnormal value maintained over the predetermined predetermined time,
And when the external light having a measurable range is introduced to the detection unit, determining the result as a sun error. The method of claim 1,
The data processing unit performs a procedure of correcting the K / S value by the following [Formula 1],
[Equation 1]
Digit _{t = a} = Digit (origin) _{t = a} -Digit (extra) _{t = a}
Here, Digit (origin) _{t = a} is the amount of light measured by the light-receiving unit of the light-emitting unit constituting the sensing unit at the time t = a, Digit (extra) _{t = a} constitutes the sensing unit at the time t = a Light quantity measured by the light-receiving part of the light-emitting part to be turned off;
The calibration procedure according to [Equation 1] is a biometric data measuring device, characterized in that for removing the light amount value due to the external light from the light amount value of the light detected by the detection unit. The method of claim 1,
The data processor performs a procedure of correcting the K / S value by the following [Formula 2],
[Formula 2]
Digit _{t = a} = Digit (origin) _{t = a1} -Digit (extra) _{t = a2}
Here, Digit (origin) _{t = a1} is the light quantity value measured by the light-receiving unit of the light-emitting unit constituting the sensing unit at the time t = a1, Digit (extra) _{t = a2} constitutes the sensing unit at the time t = a2 The light quantity measured by the light-receiving unit in the off state, t = a 부가 a1 ≒ a2),
The calibration procedure according to [Equation 2] is a biological data measuring apparatus, characterized in that for removing the light amount value due to the external light from the light amount value of the light detected by the detection unit. The method according to any one of claims 1 to 3,
The biometric data measuring device further includes a display unit which displays a result of the data processing unit. delete The method according to any one of claims 1 to 3,
And determining whether the K / S value is abnormal is determined by determining whether the K / S value exceeds 2.5. The method according to any one of claims 1 to 3,
The biological sample is blood,
The material to be analyzed in the biological sample is a high-density lipoprotein (HDL: High Density Lipoprotein), triglycerides (TG), total cholesterol (TC: Total Cholesterol), any one or more of the biological data measuring apparatus. The method of claim 7, wherein
Predetermined predetermined time determined according to the type of substance to be analyzed in the biological sample,
Biological data measuring device, characterized in that 1 second when the material to be analyzed is a high-density lipoprotein. The method of claim 7, wherein
Predetermined predetermined time determined according to the type of substance to be analyzed in the biological sample,
The biological data measuring apparatus, characterized in that 5 seconds when the substance to be analyzed is triglyceride or total cholesterol. The method according to any one of claims 1 to 3,
The data processing unit determines whether the abnormal value has maintained a constant value for the predetermined predetermined time,
And determining that the measurement strip is removed from the biometric data measuring device when the abnormal value is a constant value maintained for the predetermined predetermined time. A detector for detecting light reflected from a corresponding area on the measurement strip inserted in the measuring device main body and converting the light amount of the detected light into a digitized electric signal value, based on the electric signal value transmitted from the sensor An error determination method of a biometric data measuring apparatus including a data processor which calculates biometric data,
(a) K / S (a) = (1-R _∞ ) ² / 2R _∞ (where R _∞ = Digit _{t = a} / Digit _{t = 0} and Digit _{t = a} is the detection unit at time t = a The measured light quantity value, Digit _{t = 0} is the light quantity value measured by the detector at time t = 0, K: the extinction coefficient, S: scattering coefficient, R: the spectral reflectance measured by the detector) Calculating a K / S value for the calculation;
(b) determining whether the K / S value is an abnormal value that cannot be calculated from the biological sample itself;
(c) determining whether the abnormal value is a value maintained for a predetermined time or more determined according to the type of the substance to be analyzed in the biological sample;
(d) determining that the measurement strip has been removed from the apparatus main body when it is determined that the K / S value is an abnormal value maintained over the predetermined predetermined time; And
(e) when calculating the K / S value in step (a), if it is determined that the value of Digit _{t = a} exceeds a measurable range of the sensing unit, determining it as a sun error Error determination method of the biological data measuring apparatus, characterized in that. The method of claim 11,
When calculating the K / S value in the step (a), a procedure of correcting the K / S value is performed by the following Equation 1,
[Equation 1]
Digit _{t = a} = Digit (origin) _{t = a} -Digit (extra) _{t = a}
(Digit (origin) _{t = a} is the amount of light measured by the light-receiving unit when the light-emitting unit constituting the sensing unit is turned on at time t = a, and Digit (extra) _{t = a} is the light emission constituting the sensing unit at time t = a. Light quantity value measured by the light-receiving unit in the addition-off state;
The correction procedure according to [Equation 1] is an error determination method of the biometric data measuring apparatus, characterized in that for removing the amount of light due to the external light from the amount of light detected by the detection unit. The method of claim 11,
When calculating the K / S value in the step (a), a procedure of correcting the K / S value is performed by the following Equation 2,
[Formula 2]
Digit _{t = a} = Digit (origin) _{t = a1} -Digit (extra) _{t = a2}
Here, Digit (origin) _{t = a1} is the light quantity value measured by the light-receiving unit of the light-emitting unit constituting the sensing unit at the time t = a1, Digit (extra) _{t = a2} constitutes the sensing unit at the time t = a2 The light quantity measured by the light-receiving unit in the off state, t = a 부가 a1 ≒ a2),
The correction procedure according to [Equation 2] is an error determination method of the biological data measuring apparatus, characterized in that for removing the light amount value due to the external light from the light amount value of the light detected by the detection unit. delete The method according to any one of claims 11 to 13,
And determining whether the K / S value is an abnormal value in step (b) comprises determining whether the K / S value exceeds 2.5. The method according to any one of claims 11 to 13,
The biological sample is blood,
The material to be analyzed in the biological sample is any one or more of high density lipoprotein (HDL), triglyceride (TG), and total cholesterol (TC). Error determination method. 17. The method of claim 16,
Predetermined predetermined time determined according to the type of substance to be analyzed in the biological sample,
Error determination method of the biological data measuring apparatus, characterized in that 1 second when the substance to be analyzed is a high-density lipoprotein. 17. The method of claim 16,
Predetermined predetermined time determined according to the type of substance to be analyzed in the biological sample,
And 5 seconds when the substance to be analyzed is triglyceride or total cholesterol. The method according to any one of claims 11 to 13,
Between step (c) and step (d),
(c1) if the abnormal value is a value maintained for more than the predetermined predetermined time, determining whether the value is a constant value maintained for the predetermined predetermined time, and
Step (d) is a step of determining that the measurement strip has been removed from the biometric data measuring device when the abnormal value is a constant value maintained for the predetermined predetermined time according to the result in step (c1). An error determination method of a biometric data measuring apparatus. A detector for detecting light reflected from a corresponding area on the measurement strip inserted in the measuring device main body and converting the light amount of the detected light into a digitized electric signal value, based on the electric signal value transmitted from the sensor A computer-readable recording medium having recorded thereon a program for performing an error determination method of a biometric data measuring apparatus including a data processing unit for calculating biometric data, the method comprising:
(a) K / S (a) = (1-R _∞ ) ² / 2R _∞ (where R _∞ = Digit _{t = a} / Digit _{t = 0} and Digit _{t = a} is the detection unit at time t = a The measured light quantity value, Digit _{t = 0} is the light quantity value measured by the detector at time t = 0, K: the extinction coefficient, S: scattering coefficient, R: the spectral reflectance measured by the detector) Calculating a K / S value for the calculation;
(b) determining whether the K / S value is an abnormal value that cannot be calculated from the biological sample itself;
(c) determining whether the abnormal value is a value maintained for a predetermined time or more determined according to the type of the substance to be analyzed in the biological sample;
(d) determining that the measurement strip has been removed from the apparatus main body when it is determined that the K / S value is an abnormal value maintained over the predetermined predetermined time; And
(e) when calculating the K / S value in step (a), if it is determined that the value of Digit _{t = a} exceeds a measurable range of the sensing unit, determining it as a sun error And a computer readable recording medium. The method of claim 20,
When calculating the K / S value in the step (a), a procedure of correcting the K / S value is performed by the following Equation 1,
[Equation 1]
Digit _{t = a} = Digit (origin) _{t = a} -Digit (extra) _{t = a}
Here, Digit (origin) _{t = a} is the amount of light measured by the light-receiving unit of the light-emitting unit constituting the sensing unit at the time t = a, Digit (extra) _{t = a} constitutes the sensing unit at the time t = a Light quantity measured by the light-receiving part of the light-emitting part to be turned off;
The correction procedure according to [Equation 1] is a procedure for removing the light amount value due to the external light from the light amount value of the light detected by the detection unit. The method of claim 20,
When calculating the K / S value in the step (a), a procedure of correcting the K / S value is performed by the following Equation 2,
[Formula 2]
Digit _{t = a} = Digit (origin) _{t = a1} -Digit (extra) _{t = a2}
Here, Digit (origin) _{t = a1} is the light quantity value measured by the light-receiving unit of the light-emitting unit constituting the sensing unit at the time t = a1, Digit (extra) _{t = a2} constitutes the sensing unit at the time t = a2 The light quantity measured by the light-receiving unit in the off state, t = a 부가 a1 ≒ a2),
The correction procedure according to [Equation 2] is a procedure for removing the light amount value due to the external light from the light amount value of the light detected by the detection unit.

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