KR100781967B1 - Implants for Neural Growth Factor Supply - Google Patents

Abstract

The present invention relates to an implant for treating inferior alveolar nerve injury, having an inverted conical shape with an empty inside and an inclined upper portion, a first screw surface being formed on an inclined upper outer circumferential surface, and a second screw surface on an upper inner circumferential surface. Is formed, the lower end is composed of the injection port is formed, the fixing body is fixed by screwing in the alveolar bone; Inverted conical form of the third screw surface formed on the outer circumferential surface of the middle and the fourth screw surface formed on the outer circumferential surface of the lower end is tightly coupled to the inner circumferential surface of the upper part of the fixture; Injection part of the shape; And a growth stopper of an impermeable rubber material inserted into and installed on an inner circumferential surface of the fixture, through which a needle penetrates so as to supply a nerve growth factor to the inlet of the fixture. It relates to a dental implant.

In the practice of the present invention, in case of damage to the inferior alveolar nerve during implantation, it is possible to develop and provide an implant capable of supplying a nerve growth factor that promotes nerve regeneration to the inferior alveolar nerve injury site.

Nerve growth factor (NGF), inferior alveolar nerve, fixed body,

Description

Implant which supply NGF

1 is a cross-sectional view of the implant for supplying nerve growth factor according to an embodiment of the present invention.

Figure 2 is an exploded cross-sectional view of the implant for nerve growth factor supply according to an embodiment of the present invention.

Figure 3 is a cross-sectional view of a specific example of the implant for supplying nerve growth factor according to an embodiment of the present invention.

Figure 4 is a cross-sectional view of an embodiment performed using a syringe in one embodiment of the present invention.

Figure 5 is a cross-sectional view of an embodiment performed using a capsule in one embodiment of the present invention.

Figure 6 is a cross-sectional view of a specific embodiment carried out by injecting a nerve growth factor directly into the inside of the fixture in another embodiment of the present invention.

<Description of the symbols for the main parts of the drawings>

10: gums 20: dense bone

30: sponge bone 40: Hachizo nerve

100: fixed body 110: fixed body upper

120: the lower fixed body

150: 1st screw surface 160: 2nd screw surface

170: inlet

200: injection unit 210: injection unit top

220: discontinuing the injection unit 230: bottom of the injection unit

250: third thread 260: fourth thread

270: Home

300: nerve growth factor

400: Plastic rubber

500: dosing stopper

510: syringe 515: needle

520: nerve growth factor donor 525: injection needle

The present invention relates to an implant for supplying nerve growth factors, and more particularly, to an implant capable of supplying nerve growth factors to the lower alveolar nerve injury site when the lower alveolar nerve injury occurs during the implant procedure. .

Implantology is one of the areas of greatest interest in dentistry. Mankind's efforts to restore aesthetic, functional, and mental recovery by repairing lost teeth have been constantly made, and recently, a number of treatment procedures for repairing lost teeth using implant transplants have been studied and attempted. As the aging society progresses, the portion of implant surgery in prosthetic and periodontal treatments is gradually increasing. The National Institutes of Health (NIH) estimates that more than 300,000 implants have been treated by 1992 (NIH 1988), and that repairing lost natural teeth with biografts is a beneficial treatment for both patients and physicians. Is situated.

However, during the implantation procedure, the mandibular nerve that passes through the mandible due to the lower mandibular canal damages the mandibular nerve during the penetration of the bone fragments due to implant placement or by the drill during the implant placement. It is happening. In case of damage to the lower alveolar nerve, about 40% of patients suffer from neurosensory.

As a countermeasure against this problem, peripheral nerve damage is reconstructed with nerves from normal donors due to the development of microsurgical surgery. However, inferior alveolar nerve injury due to implant placement is particularly effective due to problems such as donor limitation, secondary damage and low recovery rate. The reality is that there is no cure.

In order to solve the above problems, an object of the present invention is to develop and provide an implant that can supply nerve growth factor to the lower alveolar nerve injury site when the lower alveolar nerve injury occurs during the implant procedure .

In order to achieve the above object, the present invention has an inverted conical shape of which the inside is hollow and the top is inclined, a first screw surface is formed on the inclined upper outer circumferential surface, and a second screw surface is formed on the upper inner circumferential surface, , The lower end is composed of the injection hole is formed, the fixing body is fixed by screwing in the alveolar bone; Inverted conical form of the third screw surface formed on the outer circumferential surface of the middle and the fourth screw surface formed on the outer circumferential surface of the lower end is tightly coupled to the inner circumferential surface of the upper part of the fixture; Injection part of the shape; And an administration pen of an impermeable rubber material inserted into the inner circumferential surface of the fixture to penetrate the needle so as to supply the nerve growth factor to the inlet of the fixture.

In addition, the present invention is characterized in that it further comprises a plastic rubber having a cylindrical shape of a size smaller than the diameter of the inner peripheral surface of the stopper stop is inserted and coupled to the fourth screw surface of the injection portion.

In addition, the nerve growth factor is provided between the injection portion or the plastic rubber and the administration stopper of the present invention, the nerve growth factor to supply the nerve growth factor to the inferior alveolar nerve through the injection needle penetrating the administration stopper including the nerve growth factor therein It is characterized in that it further comprises a donor.

In addition, the upper end of the injection portion of the present invention, characterized in that any one of the cross-shaped, straight, hexagonal and octagonal grooves configured to be removable from the fixing device.

Hereinafter, the present invention will be described in detail with reference to preferred embodiments of the accompanying drawings. 1 is a cross-sectional view of the implant for supplying nerve growth factor according to an embodiment of the present invention, Figure 2 is an exploded cross-sectional view of the implant for supplying nerve growth factor according to an embodiment of the present invention, Figure 3 is an embodiment of the present invention 4 is a cross-sectional view of a specific embodiment of the implant for supplying nerve growth factor according to the embodiment of the present invention using a syringe in one embodiment of the present invention, Figure 5 is a concrete embodiment using a capsule in one embodiment of the present invention 6 is a cross-sectional view of a specific embodiment performed by injecting a nerve growth factor directly into the fixture in another embodiment of the present invention.

1 is a cross-sectional view according to an embodiment of the present invention, Figure 2 is an exploded cross section according to an embodiment of the present invention. The fixture 100 used in this embodiment is a temporary therapeutic implant. That is, when an inferior alveolar nerve injury occurs during implantation, an implant that can supply nerve growth factor (NGF, nerve growth factor) that promotes nerve regeneration to the inferior alveolar nerve injury site.

The fixing body 100 is hollow and has an inverted conical shape with an inclined upper portion. A first screw surface 150 is formed on an outer circumferential surface of the inclined upper fixing body 110, and an upper circumferential surface is formed on the inner circumferential surface of the upper body 110. 2 screw surface 160 is formed, the lower end is the injection port 170 is formed. That is, the fixing member 100 has a reverse conical shape and a first screw surface 150 is screwed to the dense bone 20 at the upper end of the outer circumferential surface, so that the fixing member 100 does not easily fall out after insertion. It consisted of.

In addition, a second screw surface 160 is formed on the inner circumferential surface of the upper part 110 of the fixing body 100 to be screwed into the third screw surface 250 of the injection part 200 to be inserted into and coupled to the fixing body 100. It was configured to be.

And the lower end of the fixed body 120 was formed with a cylindrical injection hole 170 inside the drilled.

That is, the inside of the fixture 100 is empty so that the injection port 170 is coupled to the inside to prevent foreign matter from entering the interior of the fixture 100 before the nerve growth factor 300 is injected, the nerve growth factor 300 At the time of injection, the injection unit 200 was separated from the fixed body 100 and configured to supply a nerve growth factor 300 to the inferior alveolar nerve injury site using a syringe or the like.

The structure of the injection part 200 inserted into the upper part 110 of the fixing body 100 is formed on the outer circumferential surface of the injection part stop 220 and is coupled to the second screw surface 160 (the third screw surface ( 250), and has an inverted cone shape composed of a fourth screw surface 260 formed on the outer circumferential surface of the lower end 230. As shown in FIG.

The injection part 200 also has the shape of an inverted cone like the fixture 100, and as described above, the third screw surface 250, which is a screw surface, is formed on the outer circumferential surface of the interruption part 220 of the injection part 200. The second screw surface 160 formed on the inner circumferential surface of the fixing unit 110 was configured to be screwed, and a fourth screw surface 260 was formed on the outer circumferential surface of the lower end of the injection unit 230.

And preferably, the injection section top 210 is formed of any one of the cross groove, straight groove, hexagonal groove, octagonal groove and octagonal groove configured to detach the injection unit 200 from the fixed body 100. Can be carried out. Preferably it can be configured to implement by forming an octagonal groove.

That is, the groove 270 performs a function of allowing the injection portion to be detachable from the fixture. At this time, the shape of the groove 270 is as described above.

Inserted into and coupled to the fourth screw surface 260 of the injection portion 200, and may further comprise a plastic rubber 400 having a cylindrical shape smaller than the diameter of the inner peripheral surface of the stopper 100. have. The plastic rubber 400 is applied to the nerve growth factor donor 520 by applying pressure to the nerve growth factor donor 520 when the fixation 100 includes the nerve growth factor donor 520 as shown in FIG. 5. It serves to send the factor 300 to the inlet 170 in the lower fixture 120.

And it can be carried out by forming the injection stopper 500 of the rubber material penetrating the injection needle 515, etc. to supply a predetermined amount to the injection port 170 of the fixture 100.

The dosing stopper 500 is a rubber material to the injection needle 515, such as to pass through the nerve growth factor 300 to the damaged lower alveolar nerve at the same time to enter the lower alveolar nerve through the fixture 100 It protects against possible external pathogens.

The injection stopper 500 penetrates the injection needle 515 of the syringe 510 for injecting the nerve growth factor 300 or the injection needle 525 of the nerve growth factor donor 520. A more detailed description will be given in the embodiment of FIGS. 4 and 5.

3 is a cross-sectional view of an embodiment according to an embodiment of the present invention. In other words, the present embodiment shows a specific embodiment performed by directly implanting the implant, which is the fixture 100, to the tooth damaged the lower alveolar nerve.

That is, the fixture 100 as shown in Figure 3 is embedded in the gums, dense bones and sponges of the teeth. At this time, the first screw surface 150 of the outer circumferential surface of the upper portion 110 of the fixture 100 is coupled to the dense bone.

And the injection port 170 of the fixture 100 is placed directly on the lower extremity neural nerve passing under the sponge, using a syringe 510 or nerve growth factor donor 520 as shown in Figures 4 and 5 To prepare a condition to inject the nerve growth factor 300.

4 is a cross-sectional view of an embodiment according to another embodiment of the present invention. That is, it is sectional drawing of the specific example which supplies the nerve growth factor 300 to a lower extremity nerve using the syringe 510. FIG. First, before the supply of the usual nerve growth factor 300, the injection part 200 is in a state of being fixed to the fixture 100 as shown in FIG. When the nerve growth factor 300 is supplied using the syringe 510, the injection unit 200 is separated from the fixture 100 as shown in FIG. 4, and then the injection stopper is used using the syringe 510. Through the 500, the nerve growth factor 300 is supplied to the damaged lower alveolar nerve through the injection port 170 of the fixture 100.

After the supply of the nerve growth factor 300, the injection unit 200 may be inserted into the fixed body 100 to be combined to prevent infection of germs of the lower alveolar nerve.

5 is a cross-sectional view of an embodiment in yet another embodiment of the present invention. This embodiment is different from the embodiment of Figure 4 as a delivery medium of the nerve growth factor 300, is provided between the injection portion 200 or the plastic rubber 400 and the administration stopper 500 of the present invention, Nerve using a growth factor donor 520 including the growth factor 300 therein to supply the nerve growth factor 300 to the lower extremity nerve through the injection needle 515 penetrating the administration stopper 500. An embodiment of supplying the growth factor 300 is shown.

That is, the nerve growth factor donor 520 has a tubular capsule shape that is contracted by pressing the nerve growth factor donor 520 as shown in FIG. 5, and the nerve growth factor donor 520 is prefilled with the nerve growth factor 300 in advance. An embodiment of gradually transferring the nerve growth factor 300 to the damaged lower alveolar nerve is shown. At this time, the method of injecting the nerve growth factor 300 is a method of pushing the injection part 200 into the inside of the fixture 100 little by little using a screw groove or the injection needle 525 of the nerve growth factor donor 520. It is also possible to configure and implement an apparatus capable of adjusting the amount of injection therein.

Figure 6 is a cross-sectional view of a specific embodiment performed by injecting the nerve growth factor 300 directly into the fixture 100 in another embodiment of the present invention. In this embodiment, the diameter of the administration stopper 500 was performed to be equal to the diameter of the inner circumferential surface of the fixture 100. And it was configured integrally with the upper plastic rubber 400, the nerve growth factor 300 was injected into the empty space inside the injection unit 200 and the fixture 100.

At this time, the method of injecting the neural growth factor 300 into the injection port 170 of the fixture 100, first separating the injection portion 200 from the fixture 100, and then the appropriate amount inside the fixture 100 The nerve growth factor of 300 is injected, and the injection unit 200 is inserted into the fixture 100 again. Then, slightly twisting the injection portion 200 is raised upwards, the plastic rubber 400 and the dosing stopper 500 is configured to move upwards, whereby the internal diameter of the fixture 100 as shown in FIG. Since the structure is slightly wider toward the upper portion, the inlet 170 of the fixed body 100 is located at the lower end of the nerve growth factor 300 while opening the gap between the injection stopper 500 and the inner peripheral surface of the fixed body 100. You will be able to reach the Hachijo nerve.

In this case, the injection amount may be preferably administered by the doctor to the patient in the hospital, and may be configured to allow the patient to directly administer the patient directly at a place other than the hospital by predicting the dosage in advance.

In the practice of the invention by the above-described configuration, when damage to the inferior alveolar nerve occurs during implantation, it is possible to develop and provide an implant that can supply nerve growth factor to the inferior alveolar nerve injury site to promote nerve regeneration.

Claims (4)

The inside is hollow and has an inverted conical shape with an inclined upper portion, a first screw surface is formed on the inclined upper outer circumferential surface, a second screw surface is formed on the upper inner circumferential surface, and an inlet formed at the lower end. Fixture fixed by screwing in the alveolar bone; Inverted conical form of the third screw surface formed on the outer circumferential surface of the middle and the fourth screw surface formed on the outer circumferential surface of the lower end is tightly coupled to the inner circumferential surface of the upper part of the fixture; Injection part of the shape; And, Injection stopper of impermeable rubber material is inserted into the inner circumferential surface of the fixture to penetrate the needle so as to supply the nerve growth factor to the inlet of the fixture; Implants for supplying nerve growth factor, characterized in that comprises a. In claim 1, A plastic rubber having a cylindrical shape of a size smaller than a diameter of the inner circumferential surface of the stator suspension, in which the fourth screw surface of the injection portion is inserted and coupled; Implants for nerve growth factor supply, characterized in that further comprises. The method of claim 1 or 2, It further comprises a nerve growth factor donor provided between the injection portion or the plastic rubber and the dosing stopper to supply nerve growth factor to the lower alveolar nerve through an injection needle penetrating the dosing stopper including a nerve growth factor therein. Implants for supplying nerve growth factor, characterized in that configured. The method of claim 1 or 2, On the upper end of the injection portion, Implants for supplying nerve growth factor, characterized in that any one of the cross-shaped, straight, hexagonal grooves, octagonal grooves, decagonal grooves configured to detach the cover from the fixing device.

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