KR100552307B1 - Cosmetics Containing Herbal Extracts with Anti-Aging Effects - Google Patents

Abstract

The present invention relates to a cosmetic additive composition obtained by extracting herbal medicines, such as thorny skin, baekbokyeong, eoseongcho, licorice, antler, etc. with a solvent, the present invention is a decrease in skin physiology, cosmetic addiction, skin self-defense by using a conventional synthetic cosmetic additive composition The present invention relates to a cosmetic composition to which the herbal medicine extract having an anti-aging effect, which is rich in nutrition, has an excellent anti-inflammatory and moisturizing effect, and has a stimulating alleviating effect.

Description

Cosmetics Containing Anti-Aging Herbal Extracts {THE COSMETIC MATERIALS OF ADDING A COMPOSITE EXTRACTED FROM CHINESE MEDICINE MTERIAS HAVING EFFECT OF ANTIAGEING}

The present invention relates to an herbal extract having an anti-aging effect. More specifically, the herbal extracts having an anti-aging effect by the anti-inflammatory, moisturizing and stimulating alleviating ingredients extracted from Chinese herbal medicines thorn ogapi, baekbokyeong, eoseongcho, licorice, antler are added. It is about cosmetics.

The present invention will be described in more detail as follows.

Inflammatory response is characterized by pain, fever, redness, swelling, and loss of function due to external stimuli. Histologically, the periphery of small arteries, capillaries, and venous veins and dilatation with increased blood flow and plasma-containing protein Complex symptoms, including exudation and migration of white blood cells to inflammatory sites, are observed. Anti-inflammatory is a series of actions that prevent the destruction of tissues from external stimuli.

As a physiological regulatory gene, the skin plays a major role in the general metabolism of water in the body. Therefore, the moisture level of the stratum corneum is important for maintaining the surface of the skin soft and healthy. The moisture level of the stratum corneum is closely related to the flexibility and protection of the stratum corneum, depending on the proportion of water reaching the stratum corneum, the rate of water released by evaporation, and the capacity of the stratum corneum to retain water. In addition, the amount of moisture in the stratum corneum produced by regular keratinization is always maintained at 10-20%. This is due to the sebum film, which is a mixture of sweat and sebum, which protects the skin from the outside and prevents water from evaporating from the stratum corneum.

However, when skin ages, it plays an important role in skin elasticity

The amount of collagen, mucopolysaccharide and hyaluronic acid in the matrix decreases and the amount of insoluble collagen increases. This makes it difficult for the dermis to keep the skin hydrated and the skin rough. Furthermore, with aging, the function of sebaceous glands and sweat glands decreases, so the amount of sebum and sweat gradually decreases. This causes the sebaceous membrane to be inadequately produced and loses protection against skin hydration, resulting in dry skin and loss of translucence.

In addition, insoluble collagen in the dermis is exposed to UV light and denatures and the skin becomes less elastic. Therefore, these changes in the epidermis and dermis cause wrinkles and sags on the surface. Therefore, loss of moisturizing skin is also a major factor of skin wrinkles.

The most common irritant of skin is ultraviolet light. The skin is exposed to ultraviolet light and photochemical reactions continue to occur. The main cause of the recent damage of human skin cells by ultraviolet rays (UV-B and UV-A) is the most reactive singlegly oxygen (oxygen), which is produced by the skin during exposure to sunlight It has been reported that degeneration and peroxidation of lipids can cause dermatitis and photocarcinogenesis. Failure to absorb or defend against UV rays can result in significant damage to skin cells and tissues. As a result, cellular components such as proteins, lipids, and DNA are damaged by free radicals, and cell functions are altered to promote skin aging and skin cancer. Cause illness.

The extract of Eleutherococcus sentico (Max Maxim) contains eleuterosides, which improve basal metabolism and resistance, reduce blood sugar and gonadotropin. Clinical studies have shown that it has a radioprotective effect and inhibits tumor cell adhesion and metastasis to other tissues. It also increases the resistance of healthy tissues to anticancer drugs.

Poria cocos (Schw. Wolf.) Is a fungal nucleus that grows largely inhabited by pine roots 3 to 4 years after harvesting. Only polysaccharide, paki, contains a large amount, and when converted to pakimaran has an excellent cancer suppression effect.

Houttuynia cordata Thumb contains quercitrin, isoquercitrin and decanoylacetaldehyde, which have antibacterial and capillary potentiating effects. Outpost is used as an inflammatory and diuretic antidote. Drinking daily like tea can prevent atherosclerosis.

Glycyrrazine, known as an active ingredient of Glycyrrhiza glabra L. roots, relieves the respiratory tract and is not toxic by itself but has detoxification to many toxic substances. It also has anti-inflammatory and antibacterial effects. Licuramide, a flavonoid component of licorice, has an anti-inflammatory effect and is known for its anti-inflammatory and anti-ulcer activity.

The effect of deer antler is recorded in ancient Chinese literature and transmitted to modern times, and its effectiveness has been proved through scientific clinical experiments today. It contains a large amount of gangliosides, including amino acids, which promote hematopoietic function, enhance cellular immune function, and prevent and strengthen muscle and skeletal weakness.

Cosmetic composition containing the thorny ogapi, baekbokyeong, eoseongcho, licorice, antler mixed extract having such an effect is a cosmetic composition with excellent skin safety and efficacy by showing a safe and excellent effect on the skin in inflammation suppression, moisturizing, skin irritation test, etc. .

The use of cosmetic additives obtained from conventional petrochemical products or from mineral substances causes problems in skin respiration, secretion, blood circulation, nutrition absorption, and cosmetic poisoning.

In addition, it may cause skin deterioration of self-defense and thus lose skin protection from external harmful factors, thereby causing skin corrosion, malnutrition, aging, and exfoliation.

Such a phenomenon is to provide a cause that causes skin diseases, including blemishes, freckles, spots, pruritus and the like.

The present invention as a cosmetic additive composition to solve the problems according to the synthetic cosmetic additives and to enhance the anti-aging effect, obtain a cosmetic additive composition of the extract extracted with a solvent from the herbal medicines thorn ogapi, baekbokyeong, eoseongcho, licorice, green jelly and the like added to the cosmetic Therefore, the present invention relates to a cosmetic product to which the medicinal herb extract is rich in nutrition, has excellent anti-inflammatory and moisturizing effect and has anti-aging effect without skin irritation.

After thorough drying, the extracts were prepared in the same amount (weight), respectively, and then dried with water, ethanol, methanol, ethyl acetate, hexane, glycerin, ethylene glycol, butylene glycol, and propylene. 1-20 times one or more solvents selected from the group consisting of glycol are added. Extraction method is a method of extracting by heating at 50 to 95 ° C. for 4 to 20 hours or extracting the active ingredient at 5 to 37 ° C. for 1 to 15 days while the cooling condenser is installed to prevent the solvent from evaporating. Can be. The extract thus extracted is concentrated under reduced pressure while recovering the solvent evaporated using a distillation apparatus equipped with a cooling condenser, and then added to the cosmetic in an amount of 0.001 to 10%, preferably 0.001 to 5% as its dry weight.

In other words, it is added to the softening cream (skin), nutrition cream (lotion), nutrition cream, massage cream, essence, pack, emulsified foundation. In order to understand the content of the present invention in more detail, examples and experimental examples are as follows.

Example 1.

100 g of thorny ogapi washed with purified water, 100 g of Baekbokryeong, 100 g of Eochocho, 100 g of licorice, and 100 g of Deer Antler were added to 6 kg of 30% hydrous ethanol and extracted at room temperature for 5 days with an extractor, filtered through a 400 mesh filter cloth and filtered with 0.45 um of filter. Got it.

Example 2-9.

Using the solvent of Table 1 below and extracting in the same manner as in Example 1 and the results are shown in Table 1 below.

<Table 1>

Solvent Yield amount (kg) Example 2 Purified water 4.6 Example 3 95% ethanol 5.2 Example 4 Glycerine 4.8 Example 5 Butylene glycol 4.8 Example 6 Propylene glycol 4.8 Example 7 30% hydrous propylene glycol 4.6 Example 8 30% hydrous butylene glycol 4.7 Example 9 30% hydrous glycerin 4.7

Example 10.

100 g of thorny ogapi washed with purified water, 100 g of Baekbokryeong, 100 g of Eochocho, 100 g of licorice, and 100 g of antler in 6 kg of 30% hydrous ethanol, and a cooling condenser to prevent solvent evaporation. After filtering with a filter cloth, 5.3kg of the extract was obtained by 0.45um filter filtration.

Example 11-18.

Using the solvent of Table 2 below and extracting in the same manner as in Example 10 and the results are shown in Table 2.

<Table 2>

Solvent Yield amount (kg) Example 11 Purified water 5.1 Example 12 95% ethanol 5.3 Example 13 Glycerine 5.2 Example 14 Butylene glycol 5.2 Example 15 Propylene glycol 5.2 Example 16 30% hydrous propylene glycol 5.3 Example 17 30% hydrous butylene glycol 5.1 Example 18 30% hydrous glycerin 5.1

Example 19.

100 g of thorny ginseng washed with purified water, 100 g of Baekbokryeong, 100 g, effervescent vinegar, 100 g of licorice, 100 g of antler in 6% of 30% hydrous ethanol, extracted with an extractor for 6 days at room temperature, filtered with a 400 mesh filter cloth, and filtered with a filter of 0.45 um. The filtered solution was dried under reduced pressure using a distillation apparatus equipped with a cooling condenser to obtain 32 g of powdered extract.

Example 20-22.

Using the solvent of Table 3 below and extracting in the same manner as in Example 19 and the results are shown in Table 3.

<Table 3>

Solvent Solid content (kg) Example 20 water 38 Example 21 95% ethanol 30 Example 22 50% ethanol 32

Experiment 1. Anti-inflammatory experiment

In order to examine the anti-inflammatory effect on the extract, the left ear of the mouse was used as the control site and the right ear as the test site. Before application of the sample, the ears were washed clean with ethanol, and 20 μl of the sample was continuously applied once a day for 4 days. One hour after the last application, ethanol was applied to the left ear and arachidonic acid (2 mg / ear) was applied to the right ear. After 1 hour, the degree of ear edema was repeated three times with a micrometer.

 Anti-inflammatory effect was determined as the degree of edema inhibition based on Arachidonic acid treatment group and the results are shown in Table 5.

Table 5: Ear thickness and inflammation inhibition rate by topical application

     ※ Inhibition Rate (%) = (A￣B) / A × 100

      A: Average thickness of control ears (thickness of arachidonic acid treated ears-thickness of ears before treatment)

      B: thickness of the ear of the sample application group (thickness of arachidonic acid treated ear-thickness of the ear before treatment)

sample density(%) Solvent Ear thickness (㎛ % Inhibition Before arachidonic acid treatment After arachidonic acid treatment Arachidonic acid - ethanol 277 570 - Indomethacin One ethanol 273 415 51.5 Example 1 Extract 2.5 ethanol 277 540 10.2 Example 1 Extract 5 ethanol 265 531 9.2 Example 2 Extract 5 ethanol 275 532 12.3 Example 3 Extract 5 ethanol 290 556 9.2 Example 4 Extract 5 ethanol 301 569 8.5 Example 5 Extract 5 ethanol 257 521 9.9 Example 6 Extract 5 ethanol 245 507 10.6 Example 7 Extract 5 ethanol 275 543 8.5 Example 8 Extract 5 ethanol 258 509 14.3 Example 9 Extract 5 ethanol 292 563 7.5 Example 10 Extract 5 ethanol 275 542 8.9 Example 11 Extract 5 ethanol 274 538 9.9 Example 12 Extract 5 ethanol 265 530 9.6 Example 13 Extract 5 ethanol 254 519 9.6 Example 14 Extract 5 ethanol 275 533 11.9 Example 15 Extract 5 ethanol 292 558 9.2 Example 16 Extract 5 ethanol 245 499 13.3 Example 17 Extract 5 ethanol 285 544 11.6 Example 18 Extract 5 ethanol 258 518 11.2

Experiment 2. Anti-inflammatory experiment of powdered sample

0.5 g of powdered extract was dissolved in 100 g of ethanol, and was carried out in the same manner as in Experiment 1. The results are shown in Table 6.

Table 6: Ear thickness and inflammation inhibition rate by topical application

sample density(%) Solvent Ear thickness (㎛ % Inhibition Before arachidonic acid treatment After arachidonic acid treatment Arachidonic acid - ethanol 277 570 - Indomethacin One ethanol 273 379 63.8 Example 19 Extract 0.5 ethanol 276 539 10.2 Example 20 Extract 0.5 ethanol 265 525 11.3 Example 21 Extract 0.5 ethanol 273 539 9.2 Example 22 Extract 0.5 ethanol 273 540 8.9

As shown in Tables 5 and 6, thorny opi, baekbokyeong, eoseongcho, licorice, antler extract showed a high inhibition rate.

Experiment 3. Moisturizing Experiment (1)

In order to measure the moisturizing effect for Example 8, the thorny creeper, baekbokyeong, eoseongcho, licorice, antler mixed extract, purified water, thorny creeper, baekbokyeong, eochocho, licorice, antler mixed extract was titrated on each plate, and then completely dried CaCl ₂ . It was left for 24 hours in a desiccator adjusted to a relative humidity of 40% and a temperature of 35 ℃ using an absorbent, and the weight of each sample was measured six times and is shown in Table 7.

<Table 7> Moisturizing Effect of Medicinal Copper Pear Extract

        Hygroscopicity (%) = (Wa-Wb) / Wa × 100

        Wa is a sample weight before standing, Wb is a sample weight after standing for a predetermined time.

Sample measurement time Purified water 30% hydrous butylene glycol Prickly Pear, Baekbokyeong, Eoseongcho, Licorice, Deer Antler Extract 0 100.00 100.00 100.00 2 88.73 90.22 91.75 4 81.68 82.70 83.70 19 35.23 48.56 54.06 21 25.62 41.19 46.35 24 15.91 34.76 39.81

Experiment 4. Moisturizing Experiment (2)

Moisturizing effect was measured using Corneometer CM 825 of Courage + Khazaka Co., Ltd. for the extract of Example 8, Baekbokryeong, Eochocho, Licorice, Deer Antler. Twenty women in their 20s are washed several times with water in the upper arm 2 × 2 ㎠ and 8 compartments, and the water is removed without irritation. After 5 minutes, 10 μl of purified water, viburnum, baekbokyeong, eoseongcho, licorice, and antler mixed extract are applied to each of the two compartments evenly. After 10 minutes, measure 5 times per compartment using a Corneometer. Measure 6 times at 5 minute intervals for one compartment. The room temperature was 20 ° C and relative humidity 20%. The results are shown in Table 8.

<Table 8> Moisturizing Effect of Prickly Pear, Baekbokryeong, Eochocho, Licorice, and Antler Extract

        Moisture absorption rate (%) = Corneometer Value after sample application-Corneometer Value before sample application, data value was expressed as the average value for 20 people.

Sample time (minutes) Purified water 30% hydrous butylene glycol Prickly Pear, Baekbokyeong, Eoseongcho, Licorice, Deer Antler Extract 10 15.2 23.8 29.5 15 10.4 12.5 18.7 20 4.2 9.8 15.9 25 3.5 7.6 13.1 30 1.9 6.9 11.8 35 0.6 5.5 8.9 40 0.0 5.2 7.7

Experiment 5. Skin irritation test (closed cloth test)

This extract, 1.0%, 3.0% aqueous solution and 0.08% sodium lauryl sulfate solution was applied to a healthy adult male and female 20 people by applying a certain amount (0.2g) of each sample on the back for 24 hours and then removing the pin chamber for 4 hours. After the passage, the skin condition was visually read and the results are shown in Table 9.

<Table 9> Skin irritation test results

        ※ Criteria-: No erythema or unusual phenomenon

                     +-: Slightly reddish

                     +: Significantly redder than the surroundings

                     ++: Severe reddening and swelling around

                   {(+-) Number × 1} + {(+) number × 2} + {(++) number × 3｝

          Stimulus = ----------------------------------

                                 Number of test subjects

sample Embroidery Judgment result Stimulus ++ + +- - Sodium Lauryl Sulfate 0.08% 20 One One 3 16 0.4 Purified water 20 0 0 3 17 0.15 Example 1 Extract 1.0% + Sodium Lauryl Sulfate 0.08% 20 0 One One 18 0.15 Example 2 3.0% extract + sodium lauryl sulfate 0.08% 20 0 2 0 18 0.2 Example 3 3.0% extract + sodium lauryl sulfate 0.08% 20 0 2 One 17 0.25 Example 4 1.0% extract + sodium lauryl sulfate 0.08% 20 0 One 3 16 0.25 Example 5 3.0% extract + sodium lauryl sulfate 0.08% 20 0 2 3 15 0.35 Example 6 3.0% extract + sodium lauryl sulfate 0.08% 20 One 0 2 17 0.25 Example 7 Extract 1.0% + Sodium Lauryl Sulfate 0.08% 20 0 One 4 15 0.3 Example 8 3.0% extract + sodium lauryl sulfate 0.08% 20 0 0 2 18 0.1 Example 9 3.0% extract + sodium lauryl sulfate 0.08% 20 0 One 2 17 0.25 Example 10 extract 3.0% + sodium lauryl sulfate 0.08% 20 0 2 3 15 0.35 Example 11 Extract 1.0% + Sodium Lauryl Sulfate 0.08% 20 One One One 17 0.3 Example 12 Extract 3.0% + Sodium Lauryl Sulfate 0.08% 20 0 0 3 17 0.15 Example 13 3.0% extract + sodium lauryl sulfate 0.08% 20 One One 2 17 0.35 Example 14 Extract 3.0% + Sodium Lauryl Sulfate 0.08% 20 0 2 0 18 0.2 Example 15 Extract 1.0% + Sodium Lauryl Sulfate 0.08% 20 0 2 2 16 0.3 Example 16 Extract 3.0% + Sodium Lauryl Sulfate 0.08% 20 0 0 4 16 0.2 Example 17 Extract 3.0% + Sodium Lauryl Sulfate 0.08% 20 One 2 0 17 0.25 Example 18 Extract 1.0% + Sodium Lauryl Sulfate 0.08% 20 0 3 0 17 0.3

Experiment 6. Skin irritation test of powdered sample (closed cloth test)

0.5 g of powdered extract was dissolved in 100 g of purified water, and was carried out in the same manner as in Experiment 5. The results are shown in Table 10.

<Table 10> Skin irritation test results

sample Embroidery Judgment result Stimulus ++ + +- - Example 19 Extract 1.0% + Sodium Lauryl Sulfate 0.08% 20 0 0 3 17 0.15 Example 20 Extract 3.0% + Sodium Lauryl Sulfate 0.08% 20 0 2 2 16 0.3 Example 21 Extract 3.0% + Sodium Lauryl Sulfate 0.08% 20 One One 0 18 0.25 Example 22 Extract 1.0% + Sodium Lauryl Sulfate 0.08% 20 0 0 4 16 0.2

In the above Example, using the raw material prepared in the same manner as in the formula below.

Prescription Example 1.

Prescription examples of skin lotion (skin lotion) in cosmetics containing a mixture of thorny ogapi, baekbokyeong, eoseongcho, licorice, antler are as follows. Here thorn ogapi, baekbokyeong, eoseongcho, licorice, antler mixed extract is that of Example 8.

number Raw material Formulation Example 1 Comparative Formulation Example 1 One Prickly Pear, Baekbokyeong, Eoseongcho, Licorice, Deer Antler Extract (Example 8) 10.0 - 2  glycerin 3.0 3.0 3  Butylene glycol 2.0 2.0 4  Propylene glycol 2.0 2.0 5  Polyoxyethylene (60) Cured Castor Oil 1.00 1.0 6  ethanol 10.0 10.0 7  Triethanolamine 0.1 0.1 8  antiseptic a very small amount a very small amount 9  Pigment a very small amount a very small amount 10  Spices a very small amount a very small amount 11  Purified water Remaining amount Remaining amount

     <Manufacturing method>

Formulation Example 1 2, 3, 4, and 8 in 11 are added in order to dissolve, and then dissolved by heating 5 times at about 60 ° C. and dissolved in 10 and then added to 11 after stirring. Finally, 1, 6, 7, and 9 were added to the mixture, sufficiently stirred, and aged.

Comparative Formulation Example 1 No. 2, 3, 4, and 8 were added sequentially in order to dissolve by stirring. Then, No. 5 was heated to 60 ° C. for dissolution and 10 times were added thereto. Finally, 6, 7, and 9 are added and sufficiently stirred before aging.

Prescription Example 2.

Prescription examples of nutritional lotion in cosmetics containing a mixture of thorny ogapi, baekbokyeong, eoseongcho, licorice, antler are as follows. Here thorn ogapi, baekbokyeong, eoseongcho, licorice, antler mixed extract is that of Example 8.

number Raw material Formulation Example 2 Comparative Formulation Example 2 One Prickly Pear, Baekbokyeong, Eoseongcho, Licorice, Deer Antler Extract (Example 8) 10.0 - 2  Cytostolol 1.70 1.70 3  Polyglyceryl 2-oleate 1.50 1.50 4  Ceramide 0.7 0.7 5  Ceteares-4 1.2 1.2 6  cholesterol 1.5 1.5 7  Dicetylphosphate 0.4 0.4 8  Concentrated glycerin 5.0 5.0 9  Sunflower oil 10.0 10.0 10  Carboxy Vinyl Polymer 0.2 0.2 11  Xanthan Gum 0.3 0.3 12  antiseptic a very small amount a very small amount 13  Spices a very small amount a very small amount 14  Purified water Remaining amount Remaining amount

<Production method>

Formulation Example 2: Raw materials 2, 3, 4, 5, and 6 are homogenized at a constant temperature to be referred to as nonionic amphiphilic lipids. The nonionic amphiphilic lipid and the raw materials 1, 7, 8 and 14 are mixed and homogenized at a constant temperature, and then the raw material 9 is gradually added and homogenized at a constant temperature. Thereafter, 10, 11, 12, 13 is added to disperse to stabilize and mature.

Comparative Formulation Example 2 The raw materials 2, 3, 4, 5, and 6 were homogenized at a constant temperature to be referred to as nonionic amphiphilic lipids. The nonionic amphiphilic lipid and the raw materials 7, 8 and 14 are mixed and homogenized at a constant temperature, and then the raw material 9 is gradually added and homogenized at a constant temperature. Thereafter, 10, 11, 12, 13 is added to disperse to stabilize and mature.

Prescription Example 3

Prescription examples of nutrition cream among cosmetics containing thorny ogapi, baekbokyeong, eoseongcho, licorice, antler extracts are as follows. Here thorn ogapi, baekbokyeong, eoseongcho, licorice, antler mixed extract is that of Example 8.

number Raw material Formulation Example 3 Comparative Formulation Example 3 One Prickly Pear, Baekbokyeong, Eoseongcho, Licorice, Deer Antler Extract (Example 8) 10.0 - 2  Cytostolol 4.0 4.0 3  Polyglyceryl 2-oleate 3.0 3.0 4  Ceramide 0.7 0.7 5  Ceteares-4 2.0 2.0 6  cholesterol 3.0 3.0 7  Dicetylphosphate 0.4 0.4 8  Concentrated glycerin 5.0 5.0 9  Sunflower oil 22.0 22.0 10  Carboxy Vinyl Polymer 0.5 0.5 11  Triethanolamine 0.5 0.5 12  antiseptic a very small amount a very small amount 13  Spices a very small amount a very small amount 14  Purified water Remaining amount Remaining amount

<Manufacturing method>

Formulation Example 3: The raw materials 2, 3, 4, 5, and 6 are homogenized at a constant temperature to be referred to as nonionic amphiphilic lipids. The nonionic amphiphilic lipids and raw materials 1, 7, 8, and 14 are mixed and homogenized at a constant temperature. Then, the raw material 9 is gradually added and homogenized at a constant temperature, and then 10, 11, 12, and 13 are added and dispersed to stabilize and mature.

Comparative Formulation Example 3 The raw materials 2, 3, 4, 5, and 6 were homogenized at a constant temperature to be referred to as nonionic amphiphilic lipids. The nonionic amphiphilic lipids and raw materials 7, 8 and 14 are mixed and homogenized at a constant temperature. Then, the raw material 9 is gradually added and homogenized at a constant temperature, and then 10, 11, 12, and 13 are added and dispersed to stabilize and mature.

Test Example 1.

Experiments regarding the skin irritation effect of Formulation Examples 1 to 3 and Comparative Formulation Examples 1 to 3 in Formulation Examples 1 to 3 were measured as follows.

Formulation and 0.08% aqueous solution of sodium lauryl sulfate were applied to a healthy adult male and female 20 people with a certain amount (0.2 g) of each sample on the back for 24 hours, and the pin chamber was removed for 4 hours. The change was read and the results are shown in Table 11.

Table 11 Skin irritation test results

        ※ Criteria-: No erythema or unusual phenomenon

                     +-: Slightly reddish

                     +: Significantly redder than the surroundings

                     ++: Severe reddening and swelling around

                  {(+-) Number × 1} + {(+) number × 2} + {(++) number × 3｝

          Stimulus = ----------------------------------

                                 Number of test subjects

sample Embroidery Judgment result Stimulus ++ + +- - Sodium Lauryl Sulfate 0.08% 20 One 2 2 15 0.45 Formulation Example 1 of Formulation Example 1 + sodium lauryl sulfate 0.08% 20 0 2 2 16 0.3 Comparative Formulation Example 2 of Formulation Example 1 + sodium lauryl sulfate 0.08% 20 One One 3 15 0.4 Formulation Example 2 of Formulation Example 2 + sodium lauryl sulfate 0.08% 20 0 One 2 17 0.2 Comparative Formulation Example 2 of Formulation Example 2 + sodium lauryl sulfate 0.08% 20 0 0 4 16 0.2 Formulation Example 3 of Formulation Example 3 + sodium lauryl sulfate 0.08% 20 2 0 One 17 0.35 Comparative Formulation Example 3 of Formulation Example 3 + sodium lauryl sulfate 0.08% 20 One 2 0 17 0.35

The cosmetic additive according to the present invention is an extract of natural herbal medicines and solves problems such as deterioration of skin physiology, cosmetic poisoning, and lowering of skin power according to the use of the conventional synthetic cosmetic additive composition, while being rich in nutrition and having an anti-inflammatory and moisturizing effect. It can be said to be a cosmetic additive that can greatly increase the anti-aging effect, and the cosmetics added thereto are also rich in nutrition, excellent anti-inflammatory moisturizing effect, and can be said to be non-irritating cosmetics.

Claims (3)

After thorough drying with the same content ratios, googapi, baekbokyeong, eoseongcho, licorice and deer antler are dried in water, ethanol, methanol, ethyl acetate, hexane, copper serine, ethylene glycol, butylene glycol, and fury pyrene glycol. A dry weight of 0.001 ~ 5wt% of the concentrated solution concentrated under reduced pressure to the extraction solution extracted by adding 1 to 20 times the selected one or more solvents are added to the cosmetics. The method according to claim 1, Cosmetics added with anti-aging herbal extracts, characterized in that the cosmetics are supple cosmetics (skin), nourishing cosmetics (lotion), nutrition cream, massage cream, essence, pack, emulsified foundation. delete