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KR100379207B1 - 재조합각질층키모트립신형효소(scce) - Google Patents

재조합각질층키모트립신형효소(scce) Download PDF

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Publication number
KR100379207B1
KR100379207B1 KR1019950705748A KR19950705748A KR100379207B1 KR 100379207 B1 KR100379207 B1 KR 100379207B1 KR 1019950705748 A KR1019950705748 A KR 1019950705748A KR 19950705748 A KR19950705748 A KR 19950705748A KR 100379207 B1 KR100379207 B1 KR 100379207B1
Authority
KR
South Korea
Prior art keywords
scce
polypeptide
seq
amino acid
sequence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1019950705748A
Other languages
English (en)
Korean (ko)
Inventor
토르비요른 에겔루트
레나르트 한슨
Original Assignee
핸슨, 레나르트
토르비요른 에겔루트
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 핸슨, 레나르트, 토르비요른 에겔루트 filed Critical 핸슨, 레나르트
Application granted granted Critical
Publication of KR100379207B1 publication Critical patent/KR100379207B1/ko
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/007—Preparations for dry skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/12—Preparations containing hair conditioners
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/86—Products or compounds obtained by genetic engineering
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Birds (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Processing Of Solid Wastes (AREA)
  • Cosmetics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
KR1019950705748A 1993-06-18 1994-06-20 재조합각질층키모트립신형효소(scce) Expired - Fee Related KR100379207B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK0725/93 1993-06-18
DK93725A DK72593D0 (da) 1993-06-18 1993-06-18 Rekombinant protein

Publications (1)

Publication Number Publication Date
KR100379207B1 true KR100379207B1 (ko) 2003-09-26

Family

ID=8096824

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019950705748A Expired - Fee Related KR100379207B1 (ko) 1993-06-18 1994-06-20 재조합각질층키모트립신형효소(scce)

Country Status (21)

Country Link
US (2) US5834290A (ru)
EP (2) EP0703985B1 (ru)
JP (1) JP3542804B2 (ru)
KR (1) KR100379207B1 (ru)
CN (1) CN100457908C (ru)
AT (2) ATE315584T1 (ru)
AU (1) AU684518B2 (ru)
BR (1) BR9407015A (ru)
CA (1) CA2165197C (ru)
CZ (1) CZ289600B6 (ru)
DE (2) DE69433280T2 (ru)
DK (3) DK72593D0 (ru)
ES (2) ES2256669T3 (ru)
FI (1) FI119027B (ru)
HU (1) HU220339B (ru)
NO (1) NO322728B1 (ru)
PL (1) PL178589B1 (ru)
RU (1) RU2160312C2 (ru)
SK (1) SK284599B6 (ru)
UA (1) UA45314C2 (ru)
WO (1) WO1995000651A1 (ru)

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DK72593D0 (da) * 1993-06-18 1993-06-18 Symbicom Ab Rekombinant protein
US5976556A (en) * 1996-06-13 1999-11-02 Active Organics, Inc. Combination of acid protease enzymes and acidic buffers and uses thereof
GB9616139D0 (en) * 1996-08-01 1996-09-11 Grampian Pharm Ltd Veterinary treatments
BR9812996A (pt) * 1997-02-12 2000-08-15 Johnson & Johnson Consumer Protease de serina e composições de retinóide tópicas
US5856139A (en) * 1997-03-11 1999-01-05 Incyte Pharmaceuticals, Inc. Proline-rich acidic protein
US6294344B1 (en) 1997-03-19 2001-09-25 The Board Of Trustees Of The University Of Arkansas Methods for the early diagnosis of ovarian cancer
US6316213B1 (en) * 1997-03-19 2001-11-13 The Board Of Trustees Of The University Of Arkansas Methods for the early diagnosis of ovarian, breast and lung cancer
US6627403B2 (en) * 1997-03-19 2003-09-30 The Board Of Trustees Of The University Of Arkansas Methods for the early diagnosis of ovarian cancer
US5962300A (en) * 1997-03-26 1999-10-05 Incyte Pharmaceuticals, Inc. Human kallikrein
FR2761363B1 (fr) * 1997-03-28 1999-11-26 Oreal Polypeptide purifie de l'epiderme et son utilisation
KR20010012464A (ko) * 1997-05-12 2001-02-15 세이지 파마슈티칼스, 인크. 화상 치료 및 감염 방지를 위한 국소 분무
EP0898962A1 (en) * 1997-08-28 1999-03-03 Becton, Dickinson and Company Transdermal patches and methods for inactivating skin proteases
WO1999018219A1 (en) * 1997-10-03 1999-04-15 The Procter & Gamble Company A keratinocyte derived protease
US6589770B1 (en) 1997-10-03 2003-07-08 The Procter & Gamble Company Keratinocyte derived protease
US6262249B1 (en) 1998-06-23 2001-07-17 Chiron Corporation Pancreatic cancer genes
US20050053983A1 (en) * 1998-11-20 2005-03-10 Fuso Pharmaceutical Industries, Ltd. Novel serine protease BSSP4
SE9900431D0 (sv) * 1999-02-09 1999-02-09 Johan Stenflo Monoklonal antikropp
US6420157B1 (en) * 1999-04-30 2002-07-16 Ortho-Mcneil Pharmaceutical, Inc. Zymogen activation system
US6485957B1 (en) * 1999-04-30 2002-11-26 Ortho-Mcneil Pharmaceutical, Inc. DNA encoding the human serine protease EOS
US6458564B1 (en) * 1999-08-31 2002-10-01 Ortho-Mcneil Pharmaceutical, Inc. DNA encoding the human serine protease T
US6426199B1 (en) 1999-08-31 2002-07-30 Ortho-Mcneil Pharmaceutical, Inc. Dna
JP2003528904A (ja) * 2000-04-04 2003-09-30 カラー アクセス，インコーポレイティド 皮膚の脂質バリア機能を改善するための組成物
US7019194B2 (en) 2001-02-09 2006-03-28 Lennart Hansson SCCE modified transgenic mammals and their use as models of human disease
WO2002062135A2 (en) * 2001-02-09 2002-08-15 Egelrud Torbjoern Scce modified transgenic mammals and their use as models of human disease
GB0128629D0 (en) * 2001-11-29 2002-01-23 Univ Sheffield Method
RU2230575C2 (ru) * 2002-06-18 2004-06-20 Закрытое акционерное общество "Петроспирт" Антисептическое средство "ахдез 3000"
AU2002952597A0 (en) * 2002-11-11 2002-11-28 Schering-Plough Pty. Limited Topical parasiticide formulations and methods of treatment
RU2235324C1 (ru) * 2003-02-25 2004-08-27 Государственное учреждение Тверская государственная медицинская академия Способ определения казеинолитической активности микроорганизмов при экспресс-диагностике дисбактериоза кишечника
CN100518740C (zh) * 2003-06-06 2009-07-29 阿里克斯股份公司 杂环化合物作为scce抑制剂的制药用途
US20050106586A1 (en) * 2003-06-13 2005-05-19 Mount Sinai Hospital Detection of neurodegenerative diseases
EP1716248A1 (en) * 2004-02-03 2006-11-02 Bayer HealthCare AG Diagnostics and therapeutics for diseases associated with kallikrein 7 (klk7)
WO2005085469A2 (en) * 2004-03-09 2005-09-15 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with rho-associated protein kinase 1 (rock1)
US9205080B2 (en) 2006-11-16 2015-12-08 Transderm, Inc. Methods of treating keratin hyperproliferation disorders using mTOR inhibitors
US8476243B2 (en) 2006-12-29 2013-07-02 Transderm, Inc. Methods and compositions for treating keratin hyperproliferative disorders
FR2925312B1 (fr) * 2007-12-19 2016-12-02 Oreal Utilisation cosmetique de proteines de type desmogleine i
US8466335B2 (en) 2010-04-26 2013-06-18 The Procter & Gamble Company Personal care product
US8685309B2 (en) 2010-04-26 2014-04-01 The Procter & Gamble Company Method for making a personal care product
TWI556737B (zh) 2011-02-11 2016-11-11 陶氏農業科學公司 改良的殺蟲劑配方
US10172789B2 (en) 2013-01-24 2019-01-08 Palvella Therapeutics Llc Compositions for transdermal delivery of mTOR inhibitors
RU2585960C1 (ru) * 2015-02-17 2016-06-10 Федеральное государственное бюджетное научное учреждение "Научно-исследовательский институт медицины труда" (ФГБНУ "НИИ МТ") Способ определения наследственной предрасположенности к нарушению барьерной функции кожи
IL302385B2 (en) 2017-01-06 2024-06-01 Palvella Therapeutics Inc Anhydrous compositions of mtor inhibitors and methods of use
US20200040103A1 (en) 2018-03-14 2020-02-06 Genentech, Inc. Anti-klk5 antibodies and methods of use
CN108421034A (zh) * 2018-04-24 2018-08-21 济南磐升生物技术有限公司 激肽释放酶7在皮肤创伤愈合中的应用
WO2019237101A1 (en) * 2018-06-08 2019-12-12 The Board Of Regents Of The University Of Oklahoma Peptide therapeutics for treating alzheimer's disease and related conditions
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BR102020009679A2 (pt) * 2020-05-14 2021-11-23 Fundação Universidade Federal Do Abc - Ufabc Anticorpos recombinantes humanos para inibição da calicreína tecidual humana 7 (klk7) e uso em doenças relacionadas ao processo de descamação da pele
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Also Published As

Publication number Publication date
RU2160312C2 (ru) 2000-12-10
EP0703985B1 (en) 2003-10-29
WO1995000651A1 (en) 1995-01-05
HUT74835A (en) 1997-02-28
SK284599B6 (sk) 2005-07-01
UA45314C2 (uk) 2002-04-15
CA2165197C (en) 2009-02-10
HU220339B (hu) 2001-12-28
US5981256A (en) 1999-11-09
NO322728B1 (no) 2006-12-04
BR9407015A (pt) 1996-09-10
DE69433280D1 (de) 2003-12-04
DK72593D0 (da) 1993-06-18
CN100457908C (zh) 2009-02-04
AU6935294A (en) 1995-01-17
ES2208656T3 (es) 2004-06-16
AU684518B2 (en) 1997-12-18
CA2165197A1 (en) 1995-01-05
DE69434612D1 (de) 2006-04-06
EP1398326B1 (en) 2006-01-11
JP3542804B2 (ja) 2004-07-14
SK158695A3 (en) 1997-02-05
NO955110D0 (no) 1995-12-15
ATE252884T1 (de) 2003-11-15
HU9503618D0 (en) 1996-02-28
CN1128047A (zh) 1996-07-31
FI956075A0 (fi) 1995-12-18
CZ289600B6 (cs) 2002-03-13
US5834290A (en) 1998-11-10
JPH08511431A (ja) 1996-12-03
FI956075L (fi) 1996-02-16
EP1398326A2 (en) 2004-03-17
DK0703985T3 (da) 2004-02-23
DK1398326T3 (da) 2006-05-22
PL312189A1 (en) 1996-04-01
ATE315584T1 (de) 2006-02-15
ES2256669T3 (es) 2006-07-16
EP0703985A1 (en) 1996-04-03
PL178589B1 (pl) 2000-05-31
NO955110L (no) 1996-02-15
DE69434612T2 (de) 2006-10-05
DE69433280T2 (de) 2004-07-22
CZ333595A3 (en) 1997-03-12
FI119027B (fi) 2008-06-30
EP1398326A3 (en) 2004-03-31

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