JPS6485996A - Peptide derivative and method for using said derivative - Google Patents
Peptide derivative and method for using said derivativeInfo
- Publication number
- JPS6485996A JPS6485996A JP63148650A JP14865088A JPS6485996A JP S6485996 A JPS6485996 A JP S6485996A JP 63148650 A JP63148650 A JP 63148650A JP 14865088 A JP14865088 A JP 14865088A JP S6485996 A JPS6485996 A JP S6485996A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- treated
- protecting group
- expressed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
NEW MATERIAL:A compound (salt) expressed by formula [X is alanyl, leucyl, isoleucyl, valyl or (protected)lisyl; R is urethane type amino protecting group, provided that when X is lisyl, R is H]. USE:A substrate for measuring oxygen and reagent for measuring blood coagulation factor Xa. PREPARATION:For example, 4-morpholinoaniline is reacted with a compound expressed by the formula Z-Arg-OH (Z is benzyloxycarbonyl) in the presence of a condensing agent such as carbodiimides and the resultant product is treated with palladium carbon to remove a protecting group. Then the treated compound is reacted with a compound expressed by the formula Z-D-Lys(epsilon-For)-Gly (For is formyl) in the presence of a condensing agent and then the reaction product is treated with palladium carbon and alpha-amino protecting group is removed to provide the compound expressed by the formula.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP63148650A JPH0776232B2 (en) | 1987-06-16 | 1988-06-16 | Peptide derivative and method of using the same |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62-149894 | 1987-06-16 | ||
JP14989487 | 1987-06-16 | ||
JP63148650A JPH0776232B2 (en) | 1987-06-16 | 1988-06-16 | Peptide derivative and method of using the same |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS6485996A true JPS6485996A (en) | 1989-03-30 |
JPH0776232B2 JPH0776232B2 (en) | 1995-08-16 |
Family
ID=26478775
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP63148650A Expired - Lifetime JPH0776232B2 (en) | 1987-06-16 | 1988-06-16 | Peptide derivative and method of using the same |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPH0776232B2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20030065361A (en) * | 2002-01-29 | 2003-08-06 | 인터내셔널 비지네스 머신즈 코포레이션 | Car disk drive unit |
-
1988
- 1988-06-16 JP JP63148650A patent/JPH0776232B2/en not_active Expired - Lifetime
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20030065361A (en) * | 2002-01-29 | 2003-08-06 | 인터내셔널 비지네스 머신즈 코포레이션 | Car disk drive unit |
Also Published As
Publication number | Publication date |
---|---|
JPH0776232B2 (en) | 1995-08-16 |
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