JPS646260A - 6-iodoacyclouridine derivative - Google Patents
6-iodoacyclouridine derivativeInfo
- Publication number
- JPS646260A JPS646260A JP62160765A JP16076587A JPS646260A JP S646260 A JPS646260 A JP S646260A JP 62160765 A JP62160765 A JP 62160765A JP 16076587 A JP16076587 A JP 16076587A JP S646260 A JPS646260 A JP S646260A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- iodoacyclouridine
- derivative
- agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:The 6-iodoacyclouridine derivative of formula I (R<1> is H, halogen or lower alkyl). EXAMPLE:5-Methyl-6-iodoacyclouridine. USE:A drug. An active component of an antitumor agent. It is administered at a rate of 0.1-1g of the active component daily for adult once a day or in divided doses. PREPARATION:The compound of formula I can be produced by reacting a compound of formula II (R<2> is protecting group) with a lithiation agent (e.g. lithium diisopropylamide), reacting the resultant compound of formula IV with an iodinating agent (e.g. I2) to obtain a compound of formula III and eliminating the protecting group from the obtained compound.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62160765A JPS646260A (en) | 1987-06-27 | 1987-06-27 | 6-iodoacyclouridine derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP62160765A JPS646260A (en) | 1987-06-27 | 1987-06-27 | 6-iodoacyclouridine derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS646260A true JPS646260A (en) | 1989-01-10 |
Family
ID=15721973
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP62160765A Pending JPS646260A (en) | 1987-06-27 | 1987-06-27 | 6-iodoacyclouridine derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS646260A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000004882A1 (en) * | 1998-07-21 | 2000-02-03 | Alpenstock Holdings Limited | Formulations of anionic polysaccharides |
-
1987
- 1987-06-27 JP JP62160765A patent/JPS646260A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000004882A1 (en) * | 1998-07-21 | 2000-02-03 | Alpenstock Holdings Limited | Formulations of anionic polysaccharides |
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