JPS6426514A - Method of coating granules - Google Patents
Method of coating granulesInfo
- Publication number
- JPS6426514A JPS6426514A JP63161097A JP16109788A JPS6426514A JP S6426514 A JPS6426514 A JP S6426514A JP 63161097 A JP63161097 A JP 63161097A JP 16109788 A JP16109788 A JP 16109788A JP S6426514 A JPS6426514 A JP S6426514A
- Authority
- JP
- Japan
- Prior art keywords
- matter
- powdery
- granules
- waxy
- waxy matter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008187 granular material Substances 0.000 title abstract 6
- 239000011248 coating agent Substances 0.000 title abstract 2
- 238000000576 coating method Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000007796 conventional method Methods 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
- B01J2/006—Coating of the granules without description of the process or the device by which the granules are obtained
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2/00—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
- B01J2/14—Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic in rotating dishes or pans
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/31504—Composite [nonstructural laminate]
- Y10T428/31801—Of wax or waxy material
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Preparation (AREA)
- Glanulating (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Fertilizers (AREA)
- Disintegrating Or Milling (AREA)
- Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Paints Or Removers (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3721721A DE3721721C1 (de) | 1987-07-01 | 1987-07-01 | Verfahren zur Umhuellung von Granulaten |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS6426514A true JPS6426514A (en) | 1989-01-27 |
Family
ID=6330667
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP63161097A Pending JPS6426514A (en) | 1987-07-01 | 1988-06-30 | Method of coating granules |
Country Status (10)
Country | Link |
---|---|
US (1) | US4935246A (ja) |
EP (1) | EP0298355B1 (ja) |
JP (1) | JPS6426514A (ja) |
AT (1) | ATE58304T1 (ja) |
DE (2) | DE3721721C1 (ja) |
DK (1) | DK169164B1 (ja) |
ES (1) | ES2018870B3 (ja) |
GR (1) | GR3001354T3 (ja) |
IE (1) | IE61074B1 (ja) |
PT (1) | PT87879B (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001276597A (ja) * | 2000-03-31 | 2001-10-09 | Kobayashi Pharmaceut Co Ltd | 造粒粉体及びその製造方法及び圧縮成形固形物 |
Families Citing this family (78)
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---|---|---|---|---|
US5006368A (en) * | 1988-10-19 | 1991-04-09 | The Dow Chemical Company | Plastic particle coated with processing aid and method of coating |
DE69123075T2 (de) * | 1990-04-12 | 1997-03-20 | Shionogi Seiyaku Kk | Ueberzogene Zusammensetzung sowie Verfahren zu ihrer Herstellung |
US5290569A (en) * | 1990-04-12 | 1994-03-01 | Shionogi & Co., Ltd. | Coated composition and its preparation process |
IE65045B1 (en) * | 1990-04-28 | 1995-10-04 | Takeda Chemical Industries Ltd | Granulated preparations and method of producing the same |
AU636481B2 (en) * | 1990-05-18 | 1993-04-29 | Bracco International B.V. | Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography |
US20030194376A1 (en) * | 1990-05-18 | 2003-10-16 | Bracco International B.V. | Ultrasound contrast agents and methods of making and using them |
US5714167A (en) * | 1992-06-15 | 1998-02-03 | Emisphere Technologies, Inc. | Active agent transport systems |
SE467525B (sv) * | 1990-10-09 | 1992-08-03 | Nemo Ivarson Ab | Foerfarande foer att oeverdraga fasta partiklar i pulverform med ett i rumstemperatur hoegviskoest eller fast material |
SE9003296L (sv) * | 1990-10-16 | 1992-04-17 | Kabi Pharmacia Ab | Foerfarande foer att formulera laekemedel |
US5733531A (en) * | 1991-02-05 | 1998-03-31 | Sunsmart, Inc. | Composite UV sunblock compositions |
WO1992013517A1 (en) * | 1991-02-05 | 1992-08-20 | Sun Smart, Inc. | Visibly transparent uv sunblock agents and methods of making same |
US5223250A (en) * | 1991-02-05 | 1993-06-29 | Sun Smart, Inc. | Visibly transparent UV sunblock cosmetic compositions |
ATE119805T1 (de) * | 1991-07-11 | 1995-04-15 | Glatt Gmbh | Verfahren und einrichtung zum beschichten von teilchen. |
US5266331A (en) * | 1991-11-27 | 1993-11-30 | Euroceltique, S.A. | Controlled release oxycodone compositions |
US5478577A (en) * | 1993-11-23 | 1995-12-26 | Euroceltique, S.A. | Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level |
JPH0751288B2 (ja) * | 1991-12-25 | 1995-06-05 | 株式会社奈良機械製作所 | 粒子の複合化方法 |
SE9200858L (sv) * | 1992-03-20 | 1993-09-21 | Kabi Pharmacia Ab | Metod för framställning av pellets med fördröjd frisättning |
US20080075781A1 (en) * | 1992-11-25 | 2008-03-27 | Purdue Pharma Lp | Controlled release oxycodone compositions |
US5681811A (en) * | 1993-05-10 | 1997-10-28 | Protein Delivery, Inc. | Conjugation-stabilized therapeutic agent compositions, delivery and diagnostic formulations comprising same, and method of making and using the same |
NZ260408A (en) * | 1993-05-10 | 1996-05-28 | Euro Celtique Sa | Controlled release preparation comprising tramadol |
US6191105B1 (en) | 1993-05-10 | 2001-02-20 | Protein Delivery, Inc. | Hydrophilic and lipophilic balanced microemulsion formulations of free-form and/or conjugation-stabilized therapeutic agents such as insulin |
US5690959A (en) * | 1993-05-29 | 1997-11-25 | Smithkline Beecham Corporation | Pharmaceutical thermal infusion process |
US20070275062A1 (en) * | 1993-06-18 | 2007-11-29 | Benjamin Oshlack | Controlled release oxycodone compositions |
US7740881B1 (en) | 1993-07-01 | 2010-06-22 | Purdue Pharma Lp | Method of treating humans with opioid formulations having extended controlled release |
IL110014A (en) * | 1993-07-01 | 1999-11-30 | Euro Celtique Sa | Solid controlled-release oral dosage forms of opioid analgesics |
US5879705A (en) * | 1993-07-27 | 1999-03-09 | Euro-Celtique S.A. | Sustained release compositions of morphine and a method of preparing pharmaceutical compositions |
US6080428A (en) | 1993-09-20 | 2000-06-27 | Bova; David J. | Nicotinic acid compositions for treating hyperlipidemia and related methods therefor |
US6746691B2 (en) | 1993-09-20 | 2004-06-08 | Kos Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics |
US6129930A (en) | 1993-09-20 | 2000-10-10 | Bova; David J. | Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night |
US6676967B1 (en) * | 1993-09-20 | 2004-01-13 | Kos Pharmaceuticals, Inc. | Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia |
US6818229B1 (en) | 1993-09-20 | 2004-11-16 | Kos Pharmaceuticals, Inc. | Intermediate release nicotinic acid compositions for treating hyperlipidemia |
KR100354702B1 (ko) | 1993-11-23 | 2002-12-28 | 유로-셀티크 소시에떼 아노뉨 | 약학조성물의제조방법및서방형조성물 |
US5891471A (en) * | 1993-11-23 | 1999-04-06 | Euro-Celtique, S.A. | Pharmaceutical multiparticulates |
US5843480A (en) * | 1994-03-14 | 1998-12-01 | Euro-Celtique, S.A. | Controlled release diamorphine formulation |
US5430021A (en) * | 1994-03-18 | 1995-07-04 | Pharmavene, Inc. | Hydrophobic drug delivery systems |
GB9422154D0 (en) | 1994-11-03 | 1994-12-21 | Euro Celtique Sa | Pharmaceutical compositions and method of producing the same |
US5965161A (en) | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
IL112143A (en) * | 1994-12-26 | 1998-09-24 | Rotem Fertilizers Ltd | Method for the manufacture of sulfur-containing fertilizers |
US5827537A (en) * | 1995-05-04 | 1998-10-27 | Smithkline Beecham Corporation | Pharmaceutical thermal infusion process |
US7008668B2 (en) * | 1995-05-09 | 2006-03-07 | Phoqus Pharmaceuticals Limited | Powder coating composition for electrostatic coating of pharmaceutical substrates |
CN1183738A (zh) | 1995-05-09 | 1998-06-03 | 科洛康有限公司 | 静电包衣 |
US5789014A (en) * | 1995-12-25 | 1998-08-04 | Shin-Etsu Chemical Co., Ltd. | Method of manufacturing a solid preparation coated with non-solvent coating |
DE19635405A1 (de) * | 1996-08-31 | 1998-03-05 | Henkel Kgaa | Verfahren zur Herstellung granularer Waschmittelinhaltsstoffe |
GB9623634D0 (en) * | 1996-11-13 | 1997-01-08 | Bpsi Holdings Inc | Method and apparatus for the coating of substrates for pharmaceutical use |
IE980395A1 (en) * | 1998-05-22 | 1999-12-01 | Fuisz Internat Ltd Fuisz House | Method and appartus for forming and encapsulated product matrix |
US6703381B1 (en) | 1998-08-14 | 2004-03-09 | Nobex Corporation | Methods for delivery therapeutic compounds across the blood-brain barrier |
US6806294B2 (en) | 1998-10-15 | 2004-10-19 | Euro-Celtique S.A. | Opioid analgesic |
DE19918325A1 (de) | 1999-04-22 | 2000-10-26 | Euro Celtique Sa | Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion |
US7169889B1 (en) | 1999-06-19 | 2007-01-30 | Biocon Limited | Insulin prodrugs hydrolyzable in vivo to yield peglylated insulin |
US6309633B1 (en) | 1999-06-19 | 2001-10-30 | Nobex Corporation | Amphiphilic drug-oligomer conjugates with hydroyzable lipophile components and methods for making and using the same |
US10179130B2 (en) | 1999-10-29 | 2019-01-15 | Purdue Pharma L.P. | Controlled release hydrocodone formulations |
RU2230556C2 (ru) | 1999-10-29 | 2004-06-20 | Эро-Селтик, С.А. | Препаративные формы гидрокодона с контролируемым высвобождением |
GB0002305D0 (en) * | 2000-02-01 | 2000-03-22 | Phoqus Limited | Power material for electrostatic application |
WO2002036099A1 (en) | 2000-10-30 | 2002-05-10 | Euro-Celtique S.A. | Controlled release hydrocodone formulations |
US6867183B2 (en) * | 2001-02-15 | 2005-03-15 | Nobex Corporation | Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith |
US7060675B2 (en) * | 2001-02-15 | 2006-06-13 | Nobex Corporation | Methods of treating diabetes mellitus |
UA81224C2 (uk) * | 2001-05-02 | 2007-12-25 | Euro Celtic S A | Дозована форма оксикодону та її застосування |
US6858580B2 (en) * | 2001-06-04 | 2005-02-22 | Nobex Corporation | Mixtures of drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same |
US6828297B2 (en) * | 2001-06-04 | 2004-12-07 | Nobex Corporation | Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same |
US6835802B2 (en) * | 2001-06-04 | 2004-12-28 | Nobex Corporation | Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties |
US6828305B2 (en) * | 2001-06-04 | 2004-12-07 | Nobex Corporation | Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same |
US7713932B2 (en) * | 2001-06-04 | 2010-05-11 | Biocon Limited | Calcitonin drug-oligomer conjugates, and uses thereof |
US6713452B2 (en) * | 2001-06-04 | 2004-03-30 | Nobex Corporation | Mixtures of calcitonin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same |
US7312192B2 (en) * | 2001-09-07 | 2007-12-25 | Biocon Limited | Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same |
US7196059B2 (en) * | 2001-09-07 | 2007-03-27 | Biocon Limited | Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith |
US6913903B2 (en) * | 2001-09-07 | 2005-07-05 | Nobex Corporation | Methods of synthesizing insulin polypeptide-oligomer conjugates, and proinsulin polypeptide-oligomer conjugates and methods of synthesizing same |
US7166571B2 (en) * | 2001-09-07 | 2007-01-23 | Biocon Limited | Insulin polypeptide-oligomer conjugates, proinsulin polypeptide-oligomer conjugates and methods of synthesizing same |
SE0200154D0 (sv) * | 2002-01-21 | 2002-01-21 | Galenica Ab | New process |
WO2003105768A2 (en) * | 2002-06-13 | 2003-12-24 | Nobex Corporation | Methods of reducing hypoglycemic episodes in the treatment of diabetes mellitus |
GB2420298B (en) * | 2003-06-18 | 2006-08-23 | Phoqus Pharmaceuticals Ltd | Method and apparatus for the application of powder material to substrates |
WO2005000237A2 (en) * | 2003-06-25 | 2005-01-06 | University Of Tennessee Research Foundation | Granules containing biologically active substances |
GB0330171D0 (en) * | 2003-12-30 | 2004-02-04 | Phoqus Pharmaceuticals Ltd | Method and apparatus for the application of powder material to substrates |
GB0407312D0 (en) * | 2004-03-31 | 2004-05-05 | Phoqus Pharmaceuticals Ltd | Method and apparatus for the application of powder material to substrates |
CN103223160B (zh) | 2004-07-19 | 2015-02-18 | 比奥孔有限公司 | 胰岛素-低聚物共轭物,制剂及其用途 |
ITMI20050485A1 (it) * | 2005-03-23 | 2006-09-24 | Truffini & Regge Farmaceutici | Formulazioni granulari rivestite |
US20080069871A1 (en) * | 2006-07-21 | 2008-03-20 | Vaughn Jason M | Hydrophobic abuse deterrent delivery system |
ITMI20071374A1 (it) | 2007-07-10 | 2009-01-11 | Gnosis Spa | Sali stabili di s-adenosilmetionina e processo per il loro ottenimento. |
AU2008313248B2 (en) | 2007-10-16 | 2012-04-26 | Biocon Limited | An orally administerable solid pharmaceutical composition and a process thereof |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1077950A (fr) * | 1953-06-01 | 1954-11-12 | Procédé pour rendre des poudres hydrofuges | |
US3009775A (en) * | 1958-04-14 | 1961-11-21 | Internat Salt Company Inc | Reduction of caking tendency of salt |
BE640616A (ja) * | 1962-12-19 | |||
BR6457270D0 (pt) * | 1963-03-04 | 1973-09-20 | Merck & Co Inc | Processo de preparacao de uma composicao farmaceutica provendo uma liberacao prolongada de uma droga no aparelho gastro intestinal |
US4132753A (en) * | 1965-02-12 | 1979-01-02 | American Cyanamid Company | Process for preparing oral sustained release granules |
FR1583182A (ja) * | 1967-11-30 | 1969-10-24 | ||
DE2122355A1 (de) * | 1970-05-08 | 1971-11-25 | Lilly Industries Ltd., London | Vorrichtung und Verfahren zum Herstellen von Partikeln |
GB1346415A (en) * | 1970-05-08 | 1974-02-13 | Lilly Industries Ltd | Coating process |
DE2308890C2 (de) * | 1973-02-23 | 1983-03-31 | Kali-Chemie Ag, 3000 Hannover | Verfahren zur Herstellung von sphärischen Teilchen aus aktivem Aluminiumoxid mit hoher mechanischer Festigkeit |
SE418247B (sv) * | 1975-11-17 | 1981-05-18 | Haessle Ab | Sett att framstella kroppar med reglerad frigoring av en aktiv komponent |
JPS5362821A (en) * | 1976-11-11 | 1978-06-05 | Takeda Chem Ind Ltd | Preparation of slow-release drug |
JPS57171428A (en) * | 1981-04-13 | 1982-10-22 | Sankyo Co Ltd | Preparation of coated solid preparation |
JPS6124516A (ja) * | 1984-07-12 | 1986-02-03 | Fujisawa Pharmaceut Co Ltd | 持続性錠剤 |
-
1987
- 1987-07-01 DE DE3721721A patent/DE3721721C1/de not_active Expired
-
1988
- 1988-06-29 EP EP88110355A patent/EP0298355B1/de not_active Expired - Lifetime
- 1988-06-29 AT AT88110355T patent/ATE58304T1/de not_active IP Right Cessation
- 1988-06-29 DE DE8888110355T patent/DE3861069D1/de not_active Expired - Fee Related
- 1988-06-29 US US07/213,176 patent/US4935246A/en not_active Expired - Fee Related
- 1988-06-29 ES ES88110355T patent/ES2018870B3/es not_active Expired - Lifetime
- 1988-06-30 DK DK361488A patent/DK169164B1/da not_active IP Right Cessation
- 1988-06-30 PT PT87879A patent/PT87879B/pt not_active IP Right Cessation
- 1988-06-30 JP JP63161097A patent/JPS6426514A/ja active Pending
- 1988-06-30 IE IE199288A patent/IE61074B1/en not_active IP Right Cessation
-
1991
- 1991-01-22 GR GR90400962T patent/GR3001354T3/el unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001276597A (ja) * | 2000-03-31 | 2001-10-09 | Kobayashi Pharmaceut Co Ltd | 造粒粉体及びその製造方法及び圧縮成形固形物 |
Also Published As
Publication number | Publication date |
---|---|
EP0298355B1 (de) | 1990-11-14 |
DE3721721C1 (de) | 1988-06-09 |
ATE58304T1 (de) | 1990-11-15 |
DK169164B1 (da) | 1994-09-05 |
IE881992L (en) | 1989-01-01 |
GR3001354T3 (en) | 1992-09-11 |
DK361488D0 (da) | 1988-06-30 |
US4935246A (en) | 1990-06-19 |
ES2018870B3 (es) | 1991-05-16 |
DE3861069D1 (de) | 1990-12-20 |
PT87879B (pt) | 1993-09-30 |
PT87879A (pt) | 1989-06-30 |
EP0298355A1 (de) | 1989-01-11 |
DK361488A (da) | 1989-01-02 |
IE61074B1 (en) | 1994-09-21 |
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