JPS642587A - Production of eicosapentaenoic acid using microorganism and microorganism - Google Patents
Production of eicosapentaenoic acid using microorganism and microorganismInfo
- Publication number
- JPS642587A JPS642587A JP62156693A JP15669387A JPS642587A JP S642587 A JPS642587 A JP S642587A JP 62156693 A JP62156693 A JP 62156693A JP 15669387 A JP15669387 A JP 15669387A JP S642587 A JPS642587 A JP S642587A
- Authority
- JP
- Japan
- Prior art keywords
- epa
- microorganism
- microbial cells
- culture medium
- pasteurella
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 244000005700 microbiome Species 0.000 title abstract 3
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 title 1
- 229960005135 eicosapentaenoic acid Drugs 0.000 title 1
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 title 1
- 235000020673 eicosapentaenoic acid Nutrition 0.000 title 1
- 241000606860 Pasteurella Species 0.000 abstract 2
- 239000001963 growth medium Substances 0.000 abstract 2
- 150000002632 lipids Chemical class 0.000 abstract 2
- 230000000813 microbial effect Effects 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 239000001888 Peptone Substances 0.000 abstract 1
- 108010080698 Peptones Proteins 0.000 abstract 1
- 229940041514 candida albicans extract Drugs 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000000284 extract Substances 0.000 abstract 1
- 235000013402 health food Nutrition 0.000 abstract 1
- 238000009630 liquid culture Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 235000013372 meat Nutrition 0.000 abstract 1
- 235000015097 nutrients Nutrition 0.000 abstract 1
- 235000019319 peptone Nutrition 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000000638 solvent extraction Methods 0.000 abstract 1
- 239000012138 yeast extract Substances 0.000 abstract 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
PURPOSE:To obtain an EPA-containing lipid and EPA useful as a medicine or health food in a large amount with facilitated purification in a short time, by cultivating a specific microorganism belonging to the genus Pasteurella in a nutrient culture medium. CONSTITUTION:Pasteurella.haemolytica SCRC-2288 (FERM P-9425) is cultivated in a liquid culture medium containing one of several kinds of an yeast extract, peptone, meat extract, etc., and, as necessary, a carbon source, etc., added thereto at pH 5-9, preferably pH 7-9 and 5-30 deg.C, preferably 15-25 deg.C for 8-48hr to provide a culture. Microbial cells are collected from the resultant culture and a material containing an EPA-containing lipid is then obtained from the above-mentioned microbial cells by solvent extraction, etc., and saponified to produce free EPA or salts thereof.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62156693A JPH0761271B2 (en) | 1987-06-25 | 1987-06-25 | Method for producing lipid containing eicosapentaenoic acid using microorganism |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62156693A JPH0761271B2 (en) | 1987-06-25 | 1987-06-25 | Method for producing lipid containing eicosapentaenoic acid using microorganism |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JPH012587A JPH012587A (en) | 1989-01-06 |
| JPS642587A true JPS642587A (en) | 1989-01-06 |
| JPH0761271B2 JPH0761271B2 (en) | 1995-07-05 |
Family
ID=15633272
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62156693A Expired - Lifetime JPH0761271B2 (en) | 1987-06-25 | 1987-06-25 | Method for producing lipid containing eicosapentaenoic acid using microorganism |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH0761271B2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0324018A (en) * | 1989-06-22 | 1991-02-01 | Tosoh Corp | Lipid metabolism improving agent |
-
1987
- 1987-06-25 JP JP62156693A patent/JPH0761271B2/en not_active Expired - Lifetime
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0324018A (en) * | 1989-06-22 | 1991-02-01 | Tosoh Corp | Lipid metabolism improving agent |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0761271B2 (en) | 1995-07-05 |
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