JPS6419089A - Production of n-acetyl-beta-d-hexosamine derivative - Google Patents
Production of n-acetyl-beta-d-hexosamine derivativeInfo
- Publication number
- JPS6419089A JPS6419089A JP17486787A JP17486787A JPS6419089A JP S6419089 A JPS6419089 A JP S6419089A JP 17486787 A JP17486787 A JP 17486787A JP 17486787 A JP17486787 A JP 17486787A JP S6419089 A JPS6419089 A JP S6419089A
- Authority
- JP
- Japan
- Prior art keywords
- acetyl
- phase system
- expressed
- formula
- glucosamylchloride
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 239000007795 chemical reaction product Substances 0.000 abstract 2
- 230000006196 deacetylation Effects 0.000 abstract 2
- 238000003381 deacetylation reaction Methods 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- GAWNBKUTBVLIPL-UHFFFAOYSA-N 3-fluoro-2-nitrophenol Chemical compound OC1=CC=CC(F)=C1[N+]([O-])=O GAWNBKUTBVLIPL-UHFFFAOYSA-N 0.000 abstract 1
- ORPHLVJBJOCHBR-UHFFFAOYSA-N 403-19-0 Chemical compound OC1=CC=C([N+]([O-])=O)C=C1F ORPHLVJBJOCHBR-UHFFFAOYSA-N 0.000 abstract 1
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Landscapes
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
PURPOSE:To efficiently obtain the titled substance capable of becoming a substrate for measuring NAG-ase activity, by carrying out reaction of N-acetyl-tri- O-acetyl-alpha-D-glucosamylchloride with fluoro-nitrophenol in a different phase system and then subjecting the resultant reaction product to deacetylation. CONSTITUTION:The reaction of N-acetyl-3,4,6-tri-O-acetyl-alpha-D-glucosamylchloride expressed by formula I (AC is acetyl; X is H, halogen or methoxy) with 2- fluoro-4-nitrophenol expressed by formula II is carried out in a different phase system (preferably 2 phase system consisting of water and an organic solvent such as chloroform not mixable with water). Then the resultant reaction product is successively subjected to deacetylation to provide the aimed compound expressed by formula III.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62174867A JPH0764864B2 (en) | 1987-07-15 | 1987-07-15 | Process for producing N-acetyl-β-D-hexosamine derivative |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62174867A JPH0764864B2 (en) | 1987-07-15 | 1987-07-15 | Process for producing N-acetyl-β-D-hexosamine derivative |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6419089A true JPS6419089A (en) | 1989-01-23 |
| JPH0764864B2 JPH0764864B2 (en) | 1995-07-12 |
Family
ID=15986042
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62174867A Expired - Fee Related JPH0764864B2 (en) | 1987-07-15 | 1987-07-15 | Process for producing N-acetyl-β-D-hexosamine derivative |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH0764864B2 (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5241456A (en) * | 1990-07-02 | 1993-08-31 | General Electric Company | Compact high density interconnect structure |
| US5917149A (en) * | 1997-05-15 | 1999-06-29 | Daimlerchrysler Corporation | Flexible circuit board interconnect with strain relief |
| US5924873A (en) * | 1997-05-15 | 1999-07-20 | Chrysler Corporation | Flexible circuit board interconnect with strain relief |
| US5981870A (en) * | 1997-05-15 | 1999-11-09 | Chrysler Corporation | Flexible circuit board interconnect with strain relief |
| CN104297180A (en) * | 2014-10-10 | 2015-01-21 | 宁波普瑞柏生物技术有限公司 | Reagent used for detecting N-acetyl-beta-D-glucosaminidase |
| CN108218926A (en) * | 2018-01-24 | 2018-06-29 | 广东优尼德生物科技有限公司 | Detect substrate of N- acetylaminohydroxyphenylarsonic acid 2- deoxidation-β-D- glucopyranoside enzymes and preparation method thereof and kit |
-
1987
- 1987-07-15 JP JP62174867A patent/JPH0764864B2/en not_active Expired - Fee Related
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5241456A (en) * | 1990-07-02 | 1993-08-31 | General Electric Company | Compact high density interconnect structure |
| US5917149A (en) * | 1997-05-15 | 1999-06-29 | Daimlerchrysler Corporation | Flexible circuit board interconnect with strain relief |
| US5924873A (en) * | 1997-05-15 | 1999-07-20 | Chrysler Corporation | Flexible circuit board interconnect with strain relief |
| US5981870A (en) * | 1997-05-15 | 1999-11-09 | Chrysler Corporation | Flexible circuit board interconnect with strain relief |
| CN104297180A (en) * | 2014-10-10 | 2015-01-21 | 宁波普瑞柏生物技术有限公司 | Reagent used for detecting N-acetyl-beta-D-glucosaminidase |
| CN108218926A (en) * | 2018-01-24 | 2018-06-29 | 广东优尼德生物科技有限公司 | Detect substrate of N- acetylaminohydroxyphenylarsonic acid 2- deoxidation-β-D- glucopyranoside enzymes and preparation method thereof and kit |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0764864B2 (en) | 1995-07-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| LAPS | Cancellation because of no payment of annual fees |