JPS6395066A - Flow guide - Google Patents
Flow guideInfo
- Publication number
- JPS6395066A JPS6395066A JP61241280A JP24128086A JPS6395066A JP S6395066 A JPS6395066 A JP S6395066A JP 61241280 A JP61241280 A JP 61241280A JP 24128086 A JP24128086 A JP 24128086A JP S6395066 A JPS6395066 A JP S6395066A
- Authority
- JP
- Japan
- Prior art keywords
- balloon
- synthetic resin
- resin tube
- tip
- flow guide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229920003002 synthetic resin Polymers 0.000 claims description 36
- 239000000057 synthetic resin Substances 0.000 claims description 36
- 239000000126 substance Substances 0.000 claims description 3
- 239000000463 material Substances 0.000 description 17
- 210000004204 blood vessel Anatomy 0.000 description 15
- 230000000903 blocking effect Effects 0.000 description 9
- 239000012530 fluid Substances 0.000 description 9
- 229910052751 metal Inorganic materials 0.000 description 7
- 239000002184 metal Substances 0.000 description 7
- 238000000034 method Methods 0.000 description 7
- 229920000728 polyester Polymers 0.000 description 7
- 239000000835 fiber Substances 0.000 description 5
- 239000000853 adhesive Substances 0.000 description 4
- 230000001070 adhesive effect Effects 0.000 description 4
- 239000004760 aramid Substances 0.000 description 4
- 229920003235 aromatic polyamide Polymers 0.000 description 4
- 239000012634 fragment Substances 0.000 description 4
- 229920000126 latex Polymers 0.000 description 4
- 229920001296 polysiloxane Polymers 0.000 description 4
- 239000011248 coating agent Substances 0.000 description 3
- 238000000576 coating method Methods 0.000 description 3
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 3
- 238000003780 insertion Methods 0.000 description 3
- 230000037431 insertion Effects 0.000 description 3
- 239000004816 latex Substances 0.000 description 3
- 210000005259 peripheral blood Anatomy 0.000 description 3
- 239000011886 peripheral blood Substances 0.000 description 3
- 229920001225 polyester resin Polymers 0.000 description 3
- 239000004645 polyester resin Substances 0.000 description 3
- 229910001220 stainless steel Inorganic materials 0.000 description 3
- 208000007536 Thrombosis Diseases 0.000 description 2
- 210000001367 artery Anatomy 0.000 description 2
- 230000015271 coagulation Effects 0.000 description 2
- 238000005345 coagulation Methods 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 238000003384 imaging method Methods 0.000 description 2
- 238000002074 melt spinning Methods 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- WFKWXMTUELFFGS-UHFFFAOYSA-N tungsten Chemical compound [W] WFKWXMTUELFFGS-UHFFFAOYSA-N 0.000 description 2
- 210000002385 vertebral artery Anatomy 0.000 description 2
- 229920000049 Carbon (fiber) Polymers 0.000 description 1
- JOYRKODLDBILNP-UHFFFAOYSA-N Ethyl urethane Chemical compound CCOC(N)=O JOYRKODLDBILNP-UHFFFAOYSA-N 0.000 description 1
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 1
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 1
- 229920000271 Kevlar® Polymers 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 230000002785 anti-thrombosis Effects 0.000 description 1
- 210000002376 aorta thoracic Anatomy 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 239000012503 blood component Substances 0.000 description 1
- 230000009172 bursting Effects 0.000 description 1
- 239000004917 carbon fiber Substances 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 239000013013 elastic material Substances 0.000 description 1
- 210000003989 endothelium vascular Anatomy 0.000 description 1
- 239000003822 epoxy resin Substances 0.000 description 1
- 210000001105 femoral artery Anatomy 0.000 description 1
- 239000013305 flexible fiber Substances 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 229910052737 gold Inorganic materials 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 239000012510 hollow fiber Substances 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 230000009545 invasion Effects 0.000 description 1
- 239000004761 kevlar Substances 0.000 description 1
- 230000033001 locomotion Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920000647 polyepoxide Polymers 0.000 description 1
- 229920000098 polyolefin Polymers 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 229920002379 silicone rubber Polymers 0.000 description 1
- 239000004945 silicone rubber Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
Landscapes
- Media Introduction/Drainage Providing Device (AREA)
Abstract
(57)【要約】本公報は電子出願前の出願データであるた
め要約のデータは記録されません。(57) [Abstract] This bulletin contains application data before electronic filing, so abstract data is not recorded.
Description
【発明の詳細な説明】
（産業上の利用分野）
本発明は血管内に挿入するカテーテルをその患部に案内
する医療用フローガイドに関する。DETAILED DESCRIPTION OF THE INVENTION (Field of Industrial Application) The present invention relates to a medical flow guide for guiding a catheter inserted into a blood vessel to an affected area.
（従来の技術〉
診断や治療のため薬液を血管内へ注入するには、カテー
テルをその目的の場所へ、ガイドワイヤの案内で挿入し
なければならない。(Prior Art) To inject a medicinal solution into a blood vessel for diagnosis or treatment, a catheter must be inserted into the desired location under the guidance of a guide wire.
この目的で血管内に挿入されるガイドワイヤとしては、
主としてステンレススチール線と、ステンレススチール
線コイルより構成される金属製ガイドワイヤや、造影金
属線を合成樹脂で被覆若しくは合成樹脂製チューブに造
影金属線を内蔵した合成樹脂製ガイドワイヤが使用され
ている。各々のがイドワイヤ表面には、フッソ素樹脂や
シリコンの被膜が形成され、カテーテルとの滑りを良く
し、血液成分の凝着を予防する処置が施されている。Guidewires inserted into blood vessels for this purpose include:
Metal guidewires are mainly composed of stainless steel wire and stainless steel wire coils, and synthetic resin guidewires are used in which the contrast metal wire is coated with synthetic resin or the contrast metal wire is built into a synthetic resin tube. . A coating of fluorine resin or silicone is formed on the surface of each wire to improve slippage with the catheter and prevent blood components from adhering.
（発明が解決しようとする問題点）
上記のガイドワイヤを血管内の目的の場所に送り込むに
は、まずセルディンガー法により血管内に先端を挿入し
、次いで押す、引く、あるいは左右に回す等の操作によ
って血管内を押し進めていく。この一連の操作において
、従来のガイドワイヤは、蛇行した血管を通過しにくく
、軟かい血管内皮や血管内に生じた血栓に潜り込み、時
には破壊することがある。そこで本発明者は、上記欠点
を改良したガイドワイヤとして合成樹脂製中空糸の先端
にバルーンを装着し、血管内に挿入後バルーンを膨大さ
せ血流に乗って末梢血管へガイドワイヤ本体を牽引誘導
する医療用フローガイドワイヤを先に提案した（特開昭
５７−１９５４８号）。(Problem to be Solved by the Invention) In order to send the above-mentioned guidewire to the desired location within the blood vessel, first insert the tip into the blood vessel using the Seldinger method, and then push, pull, or turn it from side to side. It is pushed through the blood vessels by manipulation. In this series of operations, conventional guidewires have difficulty passing through tortuous blood vessels, and may penetrate into and sometimes destroy the soft vascular endothelium or thrombus that has formed within the blood vessel. Therefore, the present inventor has developed a guidewire that has improved the above-mentioned drawbacks by attaching a balloon to the tip of a synthetic resin hollow fiber, and after inserting it into the blood vessel, the balloon is inflated and carried by the blood flow to pull and guide the guidewire body to the peripheral blood vessel. We previously proposed a medical flow guide wire (Japanese Unexamined Patent Publication No. 19548/1983).
この医療用フローガイドワイヤにより、操作性の向上、
操作時間の短縮、血管壁侵襲の軽減、そしてより末梢の
血管へのカテーテル挿入が可能となり、また、カテーテ
ルを通して注入する薬液は少なくてすむなど診断、治療
の効果が向上し、術者や患者の負担を激減させた。しか
し、末梢血管へのカテーテル挿入が可能になるにしたが
い、血管に合せて直径の小さいものが好まれ、その中に
入るフローガイドも細くなり、必然的に小さいバルーン
が要求されるようになった。小さいバルーンは肉薄とな
り破裂しやすく、カテーテル内操作中に隙って千切れ血
管内に残留することがおり慎重な操作を必要とした。This medical flow guide wire improves operability,
This reduces operation time, reduces invasion of the blood vessel wall, allows catheter insertion into more peripheral blood vessels, and reduces the amount of medicine injected through the catheter, improving the effectiveness of diagnosis and treatment. The burden was drastically reduced. However, as it became possible to insert catheters into peripheral blood vessels, balloons with smaller diameters were preferred to match the blood vessels, and the flow guides that entered them became thinner, necessitating the need for smaller balloons. . Small balloons tend to be thin and rupture, and they often break open during manipulation inside the catheter and remain in the blood vessel, requiring careful manipulation.
上記の要求はバルーン内腔にバルーン先端と合成樹脂製
チューブを何らかの方法で繋ぐことにより改良されると
考えられ、用途は異なるが、公表特許公報 昭５７−５
０１１６７号にはバルーン内腔からカテーテル中空部に
渡って金属製ばねを挿入し、バルーンの先端部と後部を
固定したバルーンカテーテルが提案されている。この場
合、バルーンが破損してもその破片は血管内に残留しな
いが、金属製ばねのためにカテーテルの可撓性が損なわ
れ、また、該ばねが折れた時にはバルーンを傷つける恐
れがあった。さらに、該ばねの一部が延びてしまうと復
元しないため、該当部分のバルーンも延ばされてしまう
問題があった。It is thought that the above requirements can be improved by connecting the balloon tip and the synthetic resin tube to the balloon lumen in some way, and although the application is different, the published patent publication 1987-5
No. 01167 proposes a balloon catheter in which a metal spring is inserted from the inside of the balloon to the hollow part of the catheter to fix the tip and rear parts of the balloon. In this case, even if the balloon breaks, its fragments do not remain in the blood vessel, but the flexibility of the catheter is impaired by the metal spring, and there is a risk of damaging the balloon if the spring breaks. Furthermore, once a portion of the spring is stretched, it will not restore its original shape, so there is a problem that the corresponding portion of the balloon will also be stretched.
また、公表特許公報 昭５７−５０１１６６号には、バ
ルーンの内腔先端にワイヤの一端を取り付け、カテーテ
ル中空部を経由してワイヤを引張ることでバルーンの長
さを変えられるようにした血管閉塞個所拡張流体注入用
カテーテルが提案されており、バルーンが破損してもそ
の破片は血管内に残留しない効果を有する。しかし、一
旦拡大したバルーンを収縮させて更に挿入する場合、バ
ルーンは折れて挿入の妨げになるので、引き込む操作が
必要であった。In addition, published patent publication No. 57-501166 discloses a device that attaches one end of a wire to the tip of the lumen of the balloon, and the length of the balloon can be changed by pulling the wire through the hollow part of the catheter. A dilatation fluid injection catheter has been proposed, which has the effect that even if the balloon breaks, its fragments do not remain in the blood vessel. However, when the balloon, which has been expanded once, is deflated and inserted further, the balloon breaks and interferes with insertion, so a retraction operation is required.
（問題点を解決するための手段）
本発明者らは鋭意検討の結果、バルーン先端と該合成樹
脂製チューブを高強度の繊維などの撃留体で繋ぐことで
上述のような問題点を解決できる考えに達し、本発明を
提案した。(Means for solving the problem) As a result of intensive studies, the present inventors solved the above-mentioned problem by connecting the tip of the balloon and the synthetic resin tube with a blocking body such as high-strength fiber. We have come up with an idea and proposed the present invention.
本発明は、次の構成を有する。すなわち、（１）バルー
ンおよび合成樹脂製チューブからなる医療用フローガイ
ドにおいて、該バルーン先端と該合成樹脂製チューブを
繋ぐ撃留体を該バルーン内腔に設けたことを特徴とする
フローガイド。The present invention has the following configuration. That is, (1) a medical flow guide comprising a balloon and a synthetic resin tube, characterized in that a blocking body connecting the tip of the balloon and the synthetic resin tube is provided in the inner cavity of the balloon.
（２）合成樹脂製チューブの中空部分にレントゲン線不
透過物質を内蔵させたことを特徴とする特許請求の範囲
第１項記載のフローガイド、である。(2) The flow guide according to claim 1, characterized in that an X-ray opaque substance is incorporated in the hollow portion of the synthetic resin tube.
本発明のフローガイドは、従来の医療用フローガイドワ
イヤに要求される操作性、可撓性などのの性能を満足す
るうえに、カテーテル内腔を通して引き抜く際、万一バ
ルーンが損傷を受けても、バルーンの破片が血管内に残
留する恐れがなく、操作の安全性が確保されるという特
徴を有する。。The flow guide of the present invention not only satisfies performance requirements such as operability and flexibility for conventional medical flow guide wires, but also prevents damage to the balloon when it is pulled out through the catheter lumen. , there is no risk of balloon fragments remaining in the blood vessel, ensuring operational safety. .
次に本発明フローガイドのＭＡ造について説明する。第
１図は本発明フローガイドのバルーン及び撃留体の部分
を示す側断面図であり、第２図はフローガイド全体の側
断面図（イ）とＡ−Ａ ′部分の断面図（ロ）である。Next, the MA structure of the flow guide of the present invention will be explained. Fig. 1 is a side sectional view showing the balloon and blocking body of the flow guide of the present invention, and Fig. 2 is a side sectional view of the entire flow guide (A) and a sectional view of the A-A' section (B). It is.
又、第３図はフローガイド全体の形態を示す別の態様で
、先端部分の柔軟性を向上させるため、細く加工した合
成樹脂製チューブの先端にバルーンが装着されているこ
とを示す側面図である。In addition, Figure 3 is another aspect showing the overall form of the flow guide, and is a side view showing that a balloon is attached to the tip of a thinly processed synthetic resin tube in order to improve the flexibility of the tip. be.
本発明のフローガイドは、合成樹脂製チューブ１仝長に
連通した中空部分２のほぼ全長に内蔵するレントゲン線
不透過物質３と、先端に装着した内腔に撃留体５を内蔵
するバルーン４で構成されている。合成樹脂製チューブ
の後端は開口し、流体導入孔８が設けられコネクターや
注射器が取付けられる構造を有している。中空部分２の
空隙は流体輸送路７として利用し、バルーン内腔とは互
いに連通している。The flow guide of the present invention includes an X-ray opaque substance 3 built in almost the entire length of a hollow part 2 communicating with the length of a synthetic resin tube 1, and a balloon 4 fitted at the tip and containing a blocking body 5 in its inner cavity. It consists of The rear end of the synthetic resin tube is open and has a structure in which a fluid introduction hole 8 is provided and a connector or a syringe can be attached thereto. The void in the hollow portion 2 is used as a fluid transport path 7 and communicates with the balloon lumen.
次に各部分の構成について説明する。全長に渡って中空
部分を有する合成樹脂製チューブ１は、しなやかで表面
が滑らかなものである。更には、カテーテルとの滑りを
良くし、血栓形成予防の為に表面にシリコーンやフッ素
樹脂の被膜を形成させることは好ましい。そして、通常
は全長が均一な内外径を有する合成樹脂製チューブを使
用するが、先端付近のしなやかさを向上させるためには
、第３図に示すように先端付近を加熱延伸等により細く
加工することや、樹脂層の薄い合成樹脂製チューブを利
用することが好ましく行われる。合成樹脂製チューブの
素材は溶融紡糸の可能なものであれば特に制限されず、
ポリアミド、ポリオレフィンあるいはポリエステル樹脂
等が使用できる。Next, the configuration of each part will be explained. The synthetic resin tube 1 having a hollow portion over its entire length is flexible and has a smooth surface. Furthermore, it is preferable to form a coating of silicone or fluororesin on the surface to improve sliding with the catheter and prevent thrombus formation. Usually, a synthetic resin tube is used that has uniform inner and outer diameters over the entire length, but in order to improve the flexibility near the tip, the area near the tip is thinned by heating and stretching, etc., as shown in Figure 3. In addition, it is preferable to use a synthetic resin tube with a thin resin layer. The material of the synthetic resin tube is not particularly limited as long as it can be melt-spun.
Polyamide, polyolefin, polyester resin, etc. can be used.
合成樹脂製チュー、ブ１の中空部分２に内蔵されるレン
トゲン線不透過物質３は、ステンレス線、タングステン
線などのように剛性があり、レントゲン線照射に対して
造像力のすぐれた金属が好ましく使用され、更に先細状
に加工されていると、先端に向かうにつれて剛性が少な
くなり、合成樹脂製チューブのしなやかさを妨げること
なく手元の腰の強さが確保され操作に都合が良い。又、
レントゲン線不透過物質の直径は合成樹脂製チューブの
流体輸送路確保のため内径の８０％を越えないことが好
ましい。The X-ray opaque material 3 incorporated in the hollow portion 2 of the synthetic resin tube 1 is preferably made of a metal such as stainless steel wire or tungsten wire, which is rigid and has excellent imaging ability when irradiated with X-ray rays. When used and processed into a tapered shape, the rigidity decreases toward the tip, ensuring strength in the hand without interfering with the flexibility of the synthetic resin tube, making it convenient for operation. or,
It is preferable that the diameter of the X-ray opaque material does not exceed 80% of the inner diameter of the synthetic resin tube in order to secure a fluid transport path.
合成樹脂製チューブの先端に装着するバルーン４の素材
は、伸縮自在なゴムラテックス、シリコンゴム必るいは
ウレタン弾性体等で作られる。また、その形状は、通常
、第４図のように薄く均一な管状の膜であるが、第５図
に示すように、軸に平行な畝を内表面側に持つ管状の膜
にすれば万一破裂した場合にも裂けるだけでバルーンの
破片が分割、飛散することは防止される。そして、収縮
時のバルーン外径は合成樹脂製チューブ１の外径より小
さく、血流内に挿入された時、流体導入孔から流体輸送
路を経由して圧入された流体により、収縮時のバルーン
外径の数倍まで膨大し、血流の流れによりガイドワイヤ
を牽引していく帆の役目になる。The material of the balloon 4 attached to the tip of the synthetic resin tube is made of stretchable rubber latex, silicone rubber, urethane elastic material, or the like. In addition, the shape is usually a thin and uniform tubular membrane as shown in Figure 4, but if it is made into a tubular membrane with ridges parallel to the axis on the inner surface as shown in Figure 5, it is possible to Even if the balloon ruptures, the balloon fragments are prevented from splitting and scattering. The outer diameter of the balloon when deflated is smaller than the outer diameter of the synthetic resin tube 1, and when it is inserted into the bloodstream, the balloon when deflated is It expands to several times its outer diameter and acts as a sail that pulls the guidewire with the flow of blood.
又、バルーン４の内腔先端に内蔵させるレントゲン線不
透過物質４は、合成樹脂製チューブ１の中空部分２に内
蔵されるレントゲン線不透過物質３と同じ素材を用いる
ことができるが、その他、剛性は持たないがレントゲン
照射に対して造像力のすぐれた金属、たとえば金、白金
なども好ましく使用できる。バルーン４に内蔵される先
端と合成樹脂製チューブ１とを繋ぐ撃留体４の素材とし
ては、強くしなやかな繊維、たとえば芳香族ポリアミド
繊維や炭素繊維などが使用できる。また、バルーンの動
きを妨げないために該撃留体の長さは、膨大時のバルー
ン長さより長く、また、折畳むかスパイラル状に加工さ
れていることが好ましい。The X-ray opaque material 4 built into the tip of the inner cavity of the balloon 4 can be made of the same material as the X-ray opaque material 3 built into the hollow portion 2 of the synthetic resin tube 1; Metals that do not have rigidity but have excellent imaging ability against X-ray irradiation, such as gold and platinum, can also be preferably used. As the material of the blocking body 4 that connects the distal end of the balloon 4 and the synthetic resin tube 1, strong and flexible fibers such as aromatic polyamide fibers and carbon fibers can be used. Further, in order not to impede the movement of the balloon, it is preferable that the length of the holding body is longer than the length of the balloon when inflated, and that it is folded or processed into a spiral shape.
フローガイド後端は、流体導入孔８において開口してお
り、通常はコネクタが取付けられる構造を有している。The rear end of the flow guide is open at the fluid introduction hole 8, and usually has a structure to which a connector is attached.
本発明のフローガイドを製造する一例を挙げると、まず
中空口金を使用し通常の溶融紡糸法により合成樹脂製チ
ューブを作製する。次いで所望の長さに切断し、バルー
ンを装着する側の端を熱などにより延伸加工して細くし
ておく。別に、たとえば、凝固法で作製したラテックス
チューブを所望の長さに切り、バルーンとして用いる。To give an example of manufacturing the flow guide of the present invention, first, a synthetic resin tube is manufactured using a hollow mouthpiece by an ordinary melt spinning method. Next, it is cut to a desired length, and the end on the side where the balloon is to be attached is stretched using heat or the like to make it thin. Separately, for example, a latex tube produced by a coagulation method is cut to a desired length and used as a balloon.
該バルーンの内腔にスパイラル状に加工した撃留体を挿
入し、バルーンの外周から糸で縛ることにより該撃留体
の一端とバルーン先端に内蔵させるレントゲン線不透過
物質とを固定する。バルーンの他端で、上記の合成樹脂
製チューブの細く加工した先端を覆う。この際、該撃留
体の固定していない他端をバルーンと合成樹脂製チュー
ブの間に挟み込み、バルーン外周を糸で縛ることにより
、合成樹脂製チューブに固定する。次いで合成樹脂製チ
ューブの中空部分に、先細状に加工したレントゲン線不
透過物質を挿入し、その後端を固定する。その手段とし
ては、該レントゲン線不透過物質を蛇行させて合成樹脂
製チューブ後端の内腔壁に固定させる方法、あるいは、
接着剤を埋めて固定し、該レントゲン線不透過物質を固
定した場所より先端側の合成樹脂製チューブの壁をト刀
ルで開口し、流体導入孔を設ける方法がとられる。ざら
に、バルーンや撃留体を固定した糸による表面の凹凸や
、バルーンの先端およびバルーンと合成樹脂製チューブ
先端との段差を平滑にするため接着剤で処理する。最後
に、カテーテルとの滑りを良くし、抗血栓性を向上させ
るために合成樹脂製チューブ表面にシリコーンやフッ素
樹脂を塗布し被膜を形成させ、フローガイドは完成する
。次に実施例を挙げて本発明を更に詳細に説明する。
実施例 １：ポリエステル樹脂を素材とし、中空口金を
用いて溶融紡糸法により外径０．８ｍｍ、内径０．４ｍ
ｍのチューブを紡糸し、これを１５００ ｍｍの長さ
に切断し先端部を水蒸気加熱により延伸、先端から１０
ｍｍの部分を外径０．４ｍｍに細く延伸加工し、細い先
端を５ｍｍ残して切断した。ポリエステル樹脂をコーテ
ィングした全長１２ｍｍの芳香族ポリアミド繊維糸（登
録商標“ケブラー″）を直径０．３ｍｍ長さ２ｍｍのス
パイラル状に加工してラテックスチューブに挿入した。A spirally processed blocking body is inserted into the lumen of the balloon and tied with a thread from the outer periphery of the balloon, thereby fixing one end of the blocking body and an X-ray opaque material built into the tip of the balloon. The other end of the balloon covers the thinly processed tip of the synthetic resin tube described above. At this time, the other end of the blocking body that is not fixed is sandwiched between the balloon and the synthetic resin tube, and the balloon is fixed to the synthetic resin tube by tying the outer periphery of the balloon with a thread. Next, a tapered X-ray opaque material is inserted into the hollow part of the synthetic resin tube, and the rear end is fixed. As a means for this, a method is employed in which the X-ray radiopaque material is fixed to the inner wall of the rear end of the synthetic resin tube by meandering, or
A method is used in which an adhesive is filled and fixed, and the wall of the synthetic resin tube on the distal side of the place where the X-ray opaque material is fixed is opened with a tool to provide a fluid introduction hole. In addition, adhesive is used to smooth out the unevenness of the surface caused by the string that fixed the balloon and the blocking body, as well as the difference in level between the tip of the balloon and the tip of the synthetic resin tube. Finally, silicone or fluororesin is applied to the surface of the synthetic resin tube to form a coating to improve the slippage with the catheter and improve antithrombotic properties, and the flow guide is completed. Next, the present invention will be explained in more detail with reference to Examples.
Example 1: Polyester resin was used as the material, and the outer diameter was 0.8 mm and the inner diameter was 0.4 m by melt spinning using a hollow nozzle.
A tube of 1,500 mm is spun, cut into a length of 1500 mm, and the tip is stretched by steam heating.
The 3 mm portion was thinly stretched to an outer diameter of 0.4 mm, and cut with a 5 mm thin tip remaining. An aromatic polyamide fiber yarn (registered trademark "Kevlar") coated with a polyester resin and having a total length of 12 mm was processed into a spiral shape with a diameter of 0.3 mm and a length of 2 mm, and then inserted into a latex tube.
ラテックスチューブは凝固法で作製した外径０．８ｍｍ
、厚さ０．２ｍｍのものを用いた。先端部のレントゲン
線不透過物質には直径０．４ｍｍ、長さ１ｍｍの金線を
バルーン先端側に挿入、前記の加工した芳香族ポリアミ
ド繊維の一端を金線とバルーンの間に挟みバルーンの周
囲を４０μｍのポリエステル糸で縛り固定した。The latex tube has an outer diameter of 0.8 mm and is made using a coagulation method.
, 0.2 mm thick was used. A gold wire with a diameter of 0.4 mm and a length of 1 mm is inserted into the X-ray opaque material at the tip of the balloon, and one end of the processed aromatic polyamide fiber is sandwiched between the gold wire and the balloon to surround the balloon. was tied and fixed with 40 μm polyester thread.
次に、バルーン後端を、ポリエステルチューブの細い先
端に、間に芳香族ポリアミド繊維の他端を挟むように挿
入、４０μｍのポリエステル糸で縛り固定した。次に、
レントゲン線不透過物質として、先細状に加工した直径
０．２５ ｍｍ、長さ１４７０ｍｍのタングステン線を
細い方から、ポリエステルチューブ後端より挿入し瞬間
接着剤（登録商標“アロンアルファ三共″）を注入して
後端を固定、ポリエステルチューブの開口端を溶封、接
着剤より先端側に小孔を穿ち流体導入口を設けた。バル
ーン装着部の縛った糸の表面やバルーン先端及びバルー
ンとポリエステルチューブの段差はエポキシ樹脂（登録
商標″セメダインスーパー″）を塗布して滑らかにした
。Next, the rear end of the balloon was inserted into the thin tip of the polyester tube so that the other end of the aromatic polyamide fiber was sandwiched therebetween, and tied and fixed with a 40 μm polyester thread. next,
As an X-ray opaque material, a tapered tungsten wire with a diameter of 0.25 mm and a length of 1470 mm was inserted from the thin end into the rear end of the polyester tube, and instant adhesive (registered trademark "Aron Alpha Sankyo") was injected. The rear end of the polyester tube was fixed, the open end of the polyester tube was melt-sealed, and a small hole was drilled on the distal end side of the adhesive to provide a fluid inlet. Epoxy resin (registered trademark "CEMEDINE SUPER") was applied to the surface of the tied string at the balloon attachment part, the tip of the balloon, and the difference in level between the balloon and the polyester tube to make it smooth.
こうして作製したフローガイドのバルーン破裂試験の結
果、２．８〜３．Ｏｋｑ／ａｍで破裂するが、裂けるだ
けで千切れることはなかった。The results of the balloon bursting test of the flow guide thus prepared were 2.8 to 3. It ruptured at Okq/am, but it only tore and did not tear into pieces.
実施例 ２：実施例１で作製したフローガイドにシリコ
ーンを塗布して被膜を形成させ、エチレンオキサイドガ
スで滅菌後、臨床に供した。Example 2: Silicone was applied to the flow guide prepared in Example 1 to form a film, and after sterilization with ethylene oxide gas, it was used clinically.
セルディンガー法により大腿動脈から挿入しガイディン
グカテーテルを通して、大動脈弓と腕頭動脈の分岐点に
挿入し腕頭動脈内にバルーンの部分が入った所で０．１
５ｍ１の生理食塩水で膨大化させ、血流に乗せて更に挿
入した結果、鎖骨上動脈に入りそして椎骨動脈まで容易
に挿入ができ、カテーテルの挿入もスムーズで鮮明な椎
骨動脈造影像が得られた。また、用法いた後もバルーン
に損傷は認められなかった。Using the Seldinger technique, the balloon was inserted through the femoral artery, passed through the guiding catheter, and inserted into the bifurcation of the aortic arch and the brachiocephalic artery.
As a result of enlarging the catheter with 5 ml of physiological saline and inserting it further into the bloodstream, it was possible to easily insert the catheter into the supraclavicular artery and then to the vertebral artery, and the insertion of the catheter was smooth and a clear vertebral artery contrast image was obtained. Ta. In addition, no damage was observed to the balloon even after use.
第１図はバルーン内腔の繋留体の配置の一例を示す断面
図である。第２図は一般的なバルーンを装着したフロー
ガイドの断面図であり、第３図は先端部の柔軟性を向上
させた場合の一態様を示す側面図である。第４図と第５
図はバルーン断面について二つの態様を示す。
１ ： 合成樹脂製チューブ
２ ： 中空部分
３ ： レントゲン線不透過物質
４ ： バルーン
５ ： 繋留体
６ ： レントゲン線不透過物質
７ ： 流体輸送路
８ ： 流体導入口
９ ： 補強用畝FIG. 1 is a cross-sectional view showing an example of the arrangement of tethers in the balloon lumen. FIG. 2 is a sectional view of a flow guide equipped with a general balloon, and FIG. 3 is a side view showing an embodiment in which the flexibility of the tip portion is improved. Figures 4 and 5
The figure shows two embodiments of the balloon cross section. 1: Synthetic resin tube 2: Hollow portion 3: X-ray opaque material 4: Balloon 5: Tethering body 6: X-ray opaque material 7: Fluid transport channel 8: Fluid inlet 9: Reinforcing ridge
Claims (2)
用フローガイドにおいて、該バルーン先端と該合成樹脂
製チューブを繋ぐ繋留体を該バルーン内腔に設けたこと
を特徴とするフローガイド。(1) A medical flow guide comprising a balloon and a synthetic resin tube, characterized in that a tether that connects the tip of the balloon and the synthetic resin tube is provided in the inner cavity of the balloon.
透過物質を内蔵させたことを特徴とする特許請求の範囲
第１項記載のフローガイド。(2) The flow guide according to claim 1, characterized in that an X-ray opaque substance is incorporated in the hollow portion of the synthetic resin tube.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61241280A JPS6395066A (en) | 1986-10-13 | 1986-10-13 | Flow guide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61241280A JPS6395066A (en) | 1986-10-13 | 1986-10-13 | Flow guide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS6395066A true JPS6395066A (en) | 1988-04-26 |
Family
ID=17071909
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP61241280A Pending JPS6395066A (en) | 1986-10-13 | 1986-10-13 | Flow guide |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6395066A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0341966A (en) * | 1989-07-10 | 1991-02-22 | Terumo Corp | Guide wire |
| JP2012065804A (en) * | 2010-09-22 | 2012-04-05 | Kaneka Corp | Catheter balloon and balloon manufacturing method |
-
1986
- 1986-10-13 JP JP61241280A patent/JPS6395066A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0341966A (en) * | 1989-07-10 | 1991-02-22 | Terumo Corp | Guide wire |
| JP2012065804A (en) * | 2010-09-22 | 2012-04-05 | Kaneka Corp | Catheter balloon and balloon manufacturing method |
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