JPS61267508A - Sunscreening composition - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

DETAILED DESCRIPTION OF THE INVENTION Technical Field The present invention relates to sunscreen
The present invention relates to a novel skin protection wear sole having improved resistance to abrasion of nt(s).

BACKGROUND OF THE INVENTION The harmful effects of sunlight on the skin are well documented. Despite this, people are forced to spend long hours in the sun for work.

Others spend long periods of time in the sun due to leisure time activities and/or a desire to have a tanned appearance.

In order to protect the skin from the harmful effects of sunlight, sunscreen compositions have been developed that absorb ultraviolet radiation in the erythematous region. Many of these developments seek to improve the adhesion of sunscreens, particularly their resistance to being washed away by water. Examples of such compositions are disclosed in US Pat. No. 3,784,488, which discloses organic soluble polymers that form a continuous film on the skin.

The polymer is insoluble in sunscreens. Other documents disclosing sunscreen compositions containing polymeric materials include:
No. 3,821,363 and US Pat. No. 3,895,104 f4. These compositions all form a continuous film with the purpose of trapping the sunscreen on the skin.

Another approach to formulating adhesive sunscreen compositions is to
The use of oil-soluble polymers with sunscreens. The polymer does not form a continuous polymer film, but rather is dissolved in the sunscreen and serves to bind the sunscreen onto the skin. One such approach is disclosed in US Pat. No. 4,172,122.
This patent, like the aforementioned patent, is also incorporated herein by reference.

Although the prior art suggests numerous ways to improve the performance of sunscreen compositions, there remains a need for further improvements. One area of desired improvement is in the resistance exhibited by the composition to abrasion. The inventors have discovered that maintaining the sunscreen to polymer ratio within a range provides improved product rub-off while still maintaining pleasing aesthetics. The polymers used are soluble in oily sunscreen materials and other oily materials.

In view of the foregoing, one object of the present invention is to provide an effective sunscreen composition.

Yet another object of the invention is to provide a composition that is resistant to rub off.

Yet still another object of the invention is to have good cosmetic properties (e.g.
The object of the present invention is to provide a sunscreen composition that has a good texture (feel, rub-in, lack of excessive greasiness and/or tackiness, etc.).

These and other objects will become readily apparent from the specific description below.

Unless otherwise specified, all weights and weights in the present invention are expressed by weight.

SUMMARY OF THE INVENTION The present invention provides a sunscreen or a mixture of sunscreens from 1% to about 20%, a combination of ethylene and acrylic acid from about 0.25% to about 3%, and an emulsifier of about 2%. % to about 10% and about 70% to about 96% water. The sunscreen to polymer ratio in the composition is about 12:1 to about 15:1. The essential and optional ingredients are detailed below.

Specific Description The term "sunscreen" as used herein encompasses the specific compounds ethylhexyl p-methoxycinnamate and butylmethoxydibenzoylmethane and mixtures thereof. The former compound is a silent absorber, while the latter absorbs Ov radiation in the mu region. Other sunscreen agents useful in the present compositions are 2-hydroxy-4-methoxybenzophenone and octyldimethyl p-aminobenzoic acid. Mixtures of these are also acceptable, as are mixtures with the sunscreens mentioned above. Other sunscreens include digalloyltrioleate, 2,2-dihydroxy-4-methoxybenzophenone, ethyl 4-[bis(hydroxypropyl)aminobenzoate, 2-cyano-3,3-diphenylacrylic acid 2 -Ethylhexyl, ethylhexyl p-methoxycinnamate, salic/I/FM, 2-ethylhexyl, glyceryl p-aminobenzoate, 3°a salicylic acid, 5-tl methylcyclohexyl, methyl anthranilate, p-dimethylaminobenzoate and p-
2-ethylhexyl dimethylaminobenzoate. Mixtures of these latter compounds can also be used. These compounds do not penetrate the skin and therefore benefit to a greater extent by improved rub-off resistance than compositions that penetrate the skin.

The amount of compound useful in the compositions of the invention ranges from about 1% to about 20%.
, preferably about 7% to about 12%.

Polymers A polymer useful in the present compositions is a copolymer of ethylene and acrylic acid. These monomeric ethylene CH! ! Fresh CH2 acrylic acid 0H2ss OH WO OH exists in a polymeric form of the following formula, where the x:y ratio is from about 1:24 to about 1:9. Weight average molecular weight is approximately 3500
to about 4,500, preferably from about 4,000 to about 4,300.

Emulsifiers Clear emulsifiers for use in the present invention can be any of a variety of prior art disclosures in patents and other literature. Two patents disclosing suitable emulsifiers are described herein by reference: U.S. Pat. No. 3,755.560;
and US Pat. No. 4,421,769. Preferred emulsifiers are anionic or non-ionic emulsifiers (D
North American nib 4f1f, 1983,
It is incorporated herein by reference.

Suitable emulsifier types include ethoxylated fatty acids, engineered esters, ethoxylated ethers, ethoxylated alcohols, phosphorylated esters, polyoxyethylene fatty ether phosphates, fatty acid amides, acyl lactylates, soaps and mixtures thereof. . Fatty alcohols such as cetyl alcohol, stearyl alcohol and cetearyl alcohol are also considered emulsifiers for the purposes of the present invention.

Examples of such emulsifiers are polyoxyethylene (8) stearate, myristyl ethoxy (3) myristate,
Includes polyoxyethyl, +(100) monostearate, lauric acid jetanolamide, stearic acid monoethanolamide, hydrogenated vegetable glycerides, sodium stearoyl-2-lactylate and calcium stearoyl-2-lactylate. Soaps are also acceptable emulsifiers. Soaps can be produced in situ during processing of the composition and are preferably alkali metal or triethanolamine salts of long chain fatty acids.

Such soaps include sodium stearate, triethanolamine stearate and similar salts of lanolin fatty acids.

The emulsifier or mixture of emulsifiers is about 2% to about 10%,
Preferably it is present in an amount of about 2.5% to about 5%.

Water Water is the last of the essential ingredients of the composition and generally ranges from about 70% to about 96%, preferably from about 75% to about 8%.
Exist in 5 regrettable amounts.

Optional Ingredients In addition to the essential ingredients described above, the compositions of the present invention can contain various additional oil-soluble and water-soluble substances.

Some oil-soluble substances have a viscosity of about 10 to about 10 at 4°C.
There are non-volatile silicone fluids such as polydimethylsiloxane with 0,000 centistokes.

These siloxanes are available from Dow Corning Corporation.
Available as 200 series.

Other oil-soluble substances are fatty alcohols such as cetyl alcohol and stearyl alcohol; esters such as cetearyl valmitate, lauryl myristate and isopropyl palmitate; castor oil, radish oil, cottonseed oil, peanut oil and sesame oil, etc. oil;
Betrolatum, Cell Shinro.

waxes such as carnauba wax, beeswax, and castor wax; lanolin, its derivatives and acetylated lanolin;
Includes ingredients such as lanolin alcohol and lanolin fatty acids. Sterols such as cholesterol and phytosterols are also useful in the present invention.

These optional oil phase materials can individually constitute up to about 20 parts of the total composition, preferably up to about ios.

Additional water-soluble substances can also be present in the compositions of the invention. Humectants such as glycerin, sorbitol, propylene glycol, alkoxylated glucose and hexanetriol; tyrosine; thickeners such as carboxyvinyl polymers (E, F, Oarbopols®, manufactured by Gutdrich Company); such polymers are described in detail in U.S. Pat. No. 2,798,053, which is incorporated herein by reference.
; Ethyl cellulose, polyvinyl alcohol, carboxymethyl cellulose, vegetable gums and clays, such as Veegum trademark (R, T, /<Yagnesium aluminum silicate from Nderbilt Incorporated); Proteins and polypeptides: Preservatives agents, such as methyl, ethyl, furoyl and hifthyl esters of hydroxybenzoic acid (Parabens, manufactured by Mallinckrodt Chemical Corporation), iDT, Methyl A, (sothia, silinones and imidazolidinyl ureas). [
Germal (Gsrma) manufactured by Saraton Laboratories
and alkaline agents such as sodium hydroxide or potassium hydroxide to neutralize, if desired, a portion of the fatty acids or thickeners that may be present.

Any aqueous phase materials can individually constitute up to about 20% of the total composition, preferably up to about 10%.

The composition may also contain agents suitable for aesthetic purposes, such as perfumes and dyes.

The pH of the composition is preferably within the range of about 4.5 to about 9.

The average particle size of the dispersed oil phase material (e.g., sunscreen, polymer, fragrance, etc.) dispersed in the aqueous phase is within the range of about 5 to about 10 microns, with more than 75 particles being 12 microns. It is preferable that it is less than

Methods of Preparation Compositions of the invention may be prepared using the methods described in the Examples.

Industrial Applicability The compositions described herein are particularly suitable for protecting the skin of the body, especially of the face. Effective new approximately 0.5 mg/& skin am2~
Approximately smg/cm of skin is used and rubbed into the skin.

The following examples further describe and demonstrate preferred embodiments within the scope of the invention. The examples are given for illustrative purposes only and should not be construed as limitations on the invention, as many modifications are possible without departing from its spirit and scope.

Example I～■ The following example compositions are representative of the invention.

Ethylhexyl p-methoxycinnamate 6.00 Glycerin 3.50 Glycerol monostearate) 0.32 Cetyl alcohol 1.20 Propyl paraben
0.10 imidazolidinyl urea
0.10BDTA 4s) ytsuA
O,10 tyrosine
0.10 potassium hydroxide
Titanium oxide in 0.3
0.30 Fragrance 0.18 Water 79.90 Total 100.0: Weight factor 2.0 3.5 4.5 7.0 7.5 4.9.0
2.5 3.0 3.01G, 0 2.1.250.
450.550.751.250.56.0G 5.5
04.003.502.005.0.502.00 -
- 1.500,502.0-500.300,400
,300.20 '0.40-480.7 0.5 0
．． 3750.900.700.320.8 0.5 0
．． 8?50.800.301.2 1.0 1.0 1
．． 0 1.501.20520.520.520.52
0.520.52080.150.150.180.2
00.10060.080.080.050.050.
102 0.2 0.2 0.200.2 0.200
．． 1 0.1 0.1 0,100.1 0.100.
1 0.1 0.1 0.100.1 0.100.1
0.1 0.1 0.100.1 0.100.1
0.1 0.1 0.100.1 0.100.350
．． 370.350.3950.320.370.200
．． 300.300.400.500.4G0.080.
150.180.100.250.1583゜00.0100.0100.0100.0100.01
00.01) Provided by Allied Chemical Company as AO540A having a weight average molecular i 4271 and having an ethylene coefficient of 5 2) Polydimethylsiloxane provided by Dow Corning as DC-200 3) B, ? , Carboxyvinyl Polymer provided by Gutdrich 4) Preservative provided by Saraton Laboratories The above composition can be prepared by adding the following ingredients as described.

■Water Carbomer 934 Carbomer 941 Methylparabenpropylparabenglycerin ■Ethylhexylbutyl p-methoxycinnamateMethoxydibenzoylmethanecetyl alcoholGlyceryl stearateSteareth-100 Dimethicone petrolatum stearateEthylene/acrylate copolymer mRDTA Quaternary sodium chloride A titanium chloride n tyrosinimidazolidinyl urea fragrance composition is prepared as follows. Aqueous Phase (Par) 1) Mix the materials at 71-99° C. in a scaled mixing tank with baffles and stirrer. The oil phase (heart') is mixed at 71-110<0>C in a separate mixing tank with a stirrer.

Part until a homogeneous phase is obtained λ! and bar) II.

Next, the water phase (part ■) is mixed with the oil phase (part ■).
Pump in an amount equal to 60-1101 of part "). Maintain this oil/water premix at a temperature of about 71-99° C. and stir until a homogeneous mixture is obtained. Then
The oil/water premix is pumped into the remaining water phase (/<-)1) and maintained at a temperature of about 71-99<0>C. Then,
Add Part M ingredients while maintaining stirring and maintaining temperature between 71-99°C. The composition is then passed through a closed container equipped with an ultrasound probe at a flow rate of 0.5-a, skg/min.

The number of ultrasound images may be in the range of 15 to 40 km. The composition is further processed through a heat exchanger and/or jacket to cool it to a temperature of 71-99°C. The Part I ingredients are then added while maintaining stirring until a homogeneous mixture is obtained.

The composition is then pumped through a heat exchanger to 21
Cool to ~32°C. The composition can be recycled back to the mixing vessel while waiting for steady state operation to be achieved. One composition is then packed into glass bottles.

The compositions are all easy to apply, exhibit improved rub-off resistance, and provide protection to the treated skin area.

Example ■ A composition identical to Example I was prepared except that the amount of ethylene/acrylate copolymer was 0.5%.

The compositions were tested on a panel using the following procedure. Each panelist will:

1. Wash your face with soap and water.

2. Dry your face with a paper towel.

3. Face? Wipe with cotton soaked in ethanol.

4. First composition 200! ng on one side of the face and apply 200 mg of the second composition on the other side.

5. Wait 5 minutes after applying the product.

6. Type y lli (tygon tub) as follows:
ing ) to create a circular area of 1.50 m2 on the left side.
Extract with ethanol (3.5 ml). (a) Press the Tybon tube onto the cheek and put 3.5 ml of alcohol into the tube. (1)) After 1.5 minutes, remove the alcohol,
Transfer to a 10 ml volumetric flask, (c) repeat a and b, ((1) add 0 karari extract to the same 10 ml volumetric flask as the extract from b, (e) add other cheek and different Repeat steps a-d using a volumetric flask.

7. After 4 hours, repeat extraction steps 6a-6e.

8. Then fill each volumetric flask with ethanol.

9.07 Read the absorbance of the extract using a spectrophotometer. The device is calibrated using the absorbance of a standard sunscreen solution.

10. The fraction of sunscreen recovered is then determined by taking the relative height of the absorbance from the 4 hour extraction and the 5 minute extraction.

In comparing Example I with a composition having only 0.5% ethylene/acrylate copolymer, Example 1 retained 56% of the applied sunscreen, while the 0.5% polymer product , only held 43 chi.

Claims (1)

[Claims] 1. (A) about 1% to about 20% of an oil-soluble sunscreen agent; (B) about 0% of an ethylene-acrylic acid copolymer having the formula ▲There are mathematical formulas, chemical formulas, tables, etc.▼ (C) about 2% to about 10% emulsifier, and (D) about 70% to about 96% water, and the A:B ratio is about 12:1 to about 15%.
:1, the x:y ratio is from about 1:9 to about 1:24, and the molecular weight of B is from about 3,500 to about 4,500. 2. The composition according to claim 1, which also contains a humectant. 3. The composition according to claim 1, which also contains a thickener. 4. The sunscreen agent is selected from the group consisting of 2-ethylhexyl p-methoxycinnamate, butylmethoxydibenzoylmethane, 2-hydroxy-4-methoxy-benzophenone, octyldimethyl p-aminobenzoic acid and mixtures thereof. The composition according to claim 1. 5. The composition according to claim 1, wherein the emulsifier is a mixture of an anionic emulsifier and a nonionic emulsifier. 6. The composition according to claim 3, wherein the humectant is glycerin. 7. The composition according to claim 6, which also contains a thickener. 8. The composition according to claim 7, wherein the thickener is a carboxyvinyl polymer. 9. Claimed Section 8 further contains petrolatum.
The composition described in Section. 10. The composition of claim 1, wherein the oil phase particles have an average particle size of about 5 to about 10 microns. 11. The following steps should be carried out before exposure to ultraviolet light: (A) Oil-soluble sunburn agent about 1% to about 20%; (B) Ethylene-acrylic having the formula ▲There are mathematical formulas, chemical formulas, tables, etc.▼ (C) about 2% to about 10% emulsifier; and (D) about 70% to about 96% water, and the ratio of A:B is about 12:1 to about 15
:1, the x:y ratio is from about 1:9 to about 1:24, and the molecular weight of B is from about 3,500 to about 4,500. (E) rubbing the composition into the skin; How to protect your skin from UV rays. 12. The method according to claim 11, wherein the composition contains a mixture of an anionic emulsifier and a nonionic emulsifier as an emulsifier. 13. The composition also contains a humectant and a thickener, and the humectant is glycerin and the thickener is a carboxyvinyl polymer, and Claim 11
The method described in section. 14. The method according to claim 13, wherein the composition further contains petrolatum.