JPS60148561A - Blood circuit chamber - Google Patents

Abstract

(57) [Summary] This bulletin contains application data before electronic filing, so abstract data is not recorded.

Description

DETAILED DESCRIPTION OF THE INVENTION (Industrial Application Field) The present invention relates to a blood circuit for guiding blood to a blood processing device and returning the treated blood to the body in blood purification and other extracorporeal blood circulation. This relates to the chamber used in

(Prior Art and Problems) In extracorporeal circulation treatment of blood, a chamber is provided in the blood circuit for air trapping and pressure relief, and a mesh is placed inside the chamber to remove foreign substances.

Conventionally used blood circuit chambers usually have a diameter of 15 to 25III11, as shown in FIG. Length 40~l? Omm, almost cylindrical (diameter/length ≦
(preferably 0.5), the inside of the chamber is divided into two sections, a blood introduction side and a blood discharge side, by a mesh internally fixed to the body of the chamber.

In the conventional chamber/height chamber shown in Figure 1, air tends to accumulate at the interface between the mensch and the chamber body (A) when filling with physiological saline, which causes dialysis without anticoagulants and strong blood coagulation system activity. In patients, coagulation occurs in the mensch area, and the area of the mesh membrane cannot be used effectively enough, resulting in a sudden increase in pressure. Furthermore, due to the structure in which the mesh is fixed to the body of the chamber, there is a limit to the effective membrane area of the mesh, and there is a drawback that coagulum, pressure shoulders, etc. are likely to occur.

For example, the conventional chamber of the type shown in FIG.
3) Each unit member of the blood inlet tube (4), blood outlet tube (5), and mesh (6) is assembled in at least four steps, which essentially requires multiple steps and reduces productivity. We cannot avoid cost increases.

In particular, the process of attaching the mesh (6) involves heat welding and laser welding, which requires special techniques.The structure of the mesh itself is also not easy to mold, which increases the cost of the entire blood circuit and reduces costs. It is a major factor in productivity.

(Object of the Invention) The present invention improves the above-mentioned conventional problems and provides an improved chamber with high performance and high productivity.

(Structure and operation of the invention) The blood circuit chamber of the present invention has a mesh fixed internally at both upper and lower ends of the chamber so as to divide the chamber into two compartments, a blood introduction compartment and a blood discharge compartment. It is characterized by points.

That is, as shown in FIG. 2(d), the mesh (6) built into the chamber is located at one end (2) of the chamber.
and the lower end part (3) and the body part (1) (1') are inscribed and fixed, and there are a compartment (7) where the blood inlet pipe (4) opens, and a compartment (7) where the blood discharge pipe (5) opens. 8) The inside of the chamber is divided into two sections, left and right.

The shape of the chamber is not particularly limited. It can be of any shape as long as it is almost cylindrical, whether it is a welter type (b) as shown in Figure 1, a type with only one end tapered (a), or a type with both ends flat. good.

In addition, in the specification, "two ends", "lower end", and "both ends" refer to the part where the inner diameter changes when the inner diameter of the chamber gradually becomes thinner, such as in a welter type. shall point.

The mesh has both ends (2) as shown in Figure 2(a).
There is no need to fix it perpendicularly to (3), and it can be installed at any angle. In the example of FIG. 2(b), the mesh center line α and the central extension line β of the blood discharge tube form an inclination of an angle γ.

A preferable mesh slope is γ≦306.

The means for adhering the mesh may be any adhesive, physical adhesion such as ultrasonic waves, laser, etc., melt adhesion during molding, or encapsulation.

FIG. 3 shows an example of fixing the mesh in the chamber of the present invention. (a) shows a flat mesh attached as shown in FIG. 2(a), (b) shows a corrugated mesh, and (c) shows an example in which a cylindrical mesh is added.

In this case, the filtration area of the mesh can be changed freely, and by using a corrugated mesh as shown in (b), the membrane area can be particularly increased.

By increasing the mesh membrane area in this way, it is possible to downsize the chamber.

Additionally, even if blood clots occur in the mesh area due to anticoagulant-free dialysis, as shown in Figure 4, by raising the blood clotting area one by one, it is possible to prevent the internal pressure from increasing. Control of circuit internal pressure is easy.

Furthermore, the chamber of the present invention can omit the conventional cap welding and mensch welding processes by performing the manufacturing process in the following order (a) and (b), thereby increasing productivity. I can do it.

(a) Place the mesh (6) on the -1- part of the body part (+) on one side of the chamber made using a mold.

(b) Place the body part (1) on one side of the chamber made using a mold and bond it together.

Although not shown, the chamber of the present invention may be equipped with a pressure monitor, a level adjustment pipe, etc.

Next, the present invention will be further explained with reference to Examples.

(Example) Diameter 20fflI11, length 150mm (7) In the chamber, the type shown in Fig. 2 (a) of the present invention, the conventional type shown in Fig. 1 (a) (the mesh is a gate), and the type 1 shown in Fig. Figure (b)
Three types of chambers (with convex sides) were tested under the following conditions.

Made of polyethylene 70 with a membrane area of 3cm''~50crn'
A mesh chamber mesh was used, and 1.5 g of saline was used at the start, but no special air bleeding was performed.

In the same test animal, blood was 1100 mJl/min, heparin amount was 50 units/kg before circulation, and 500 units/kg during circulation.
Extracorporeal circulation was performed for 5 hours under the following conditions. The blood clotting and remaining blood conditions in the blood processing device and the blood circuit chamber at this time are shown in the table.

The blood processing device has a membrane area of 1.0 m' using approximately 10,000 small cuproammonium rayon fibers with an inner diameter of 200 mm.
I used the one from

As is clear from the table, in the chamber of the present invention, as compared to the conventional chamber, blood coagulation and residual blood in the chamber were significantly reduced due to improved air release, etc. Therefore, the chamber of the present invention is expected to be particularly effective in dialysis without anticoagulation and with low blood flow rate.

[Brief explanation of drawings]

Fig. 1 is a conventional chamber, Figs. 2 to 4 are explanatory diagrams of the improved chamber of the present invention, Fig. 3 is a cross-sectional view of various improved chambers, and Fig. 4 is a diagram showing the blood circulation situation. It is. 1.1 Torso 5 Blood discharge tube 2 Upper end 6 Mesh 3 Lower end 7 Blood introduction section 4 Blood introduction tube 8 Blood discharge section Agent Patent attorney Toshitetsu Sasaki Figure 1 Figure 2 (a) (b) 3 Figure (a) ″lA4 diagram

Claims (1)

[Claims] A blood circuit chamber, characterized in that the inside of the channel is divided into a blood introduction section and a blood discharge section by meshes inscribed and fixed in the channel at both ends of the chamber.