JPS60133852A - Novel natto (fermented soybean) product - Google Patents
Novel natto (fermented soybean) productInfo
- Publication number
- JPS60133852A JPS60133852A JP58242126A JP24212683A JPS60133852A JP S60133852 A JPS60133852 A JP S60133852A JP 58242126 A JP58242126 A JP 58242126A JP 24212683 A JP24212683 A JP 24212683A JP S60133852 A JPS60133852 A JP S60133852A
- Authority
- JP
- Japan
- Prior art keywords
- natto
- product
- suppressing
- fermented soybean
- bacteria
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 235000013557 nattō Nutrition 0.000 title claims abstract description 22
- 244000068988 Glycine max Species 0.000 title abstract description 5
- 235000010469 Glycine max Nutrition 0.000 title abstract description 5
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical class OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims description 8
- 241000894006 Bacteria Species 0.000 abstract description 11
- 244000063299 Bacillus subtilis Species 0.000 abstract description 6
- 235000014469 Bacillus subtilis Nutrition 0.000 abstract description 6
- FTSSQIKWUOOEGC-RULYVFMPSA-N fructooligosaccharide Chemical compound OC[C@H]1O[C@@](CO)(OC[C@@]2(OC[C@@]3(OC[C@@]4(OC[C@@]5(OC[C@@]6(OC[C@@]7(OC[C@@]8(OC[C@@]9(OC[C@@]%10(OC[C@@]%11(O[C@H]%12O[C@H](CO)[C@@H](O)[C@H](O)[C@H]%12O)O[C@H](CO)[C@@H](O)[C@@H]%11O)O[C@H](CO)[C@@H](O)[C@@H]%10O)O[C@H](CO)[C@@H](O)[C@@H]9O)O[C@H](CO)[C@@H](O)[C@@H]8O)O[C@H](CO)[C@@H](O)[C@@H]7O)O[C@H](CO)[C@@H](O)[C@@H]6O)O[C@H](CO)[C@@H](O)[C@@H]5O)O[C@H](CO)[C@@H](O)[C@@H]4O)O[C@H](CO)[C@@H](O)[C@@H]3O)O[C@H](CO)[C@@H](O)[C@@H]2O)[C@@H](O)[C@@H]1O FTSSQIKWUOOEGC-RULYVFMPSA-N 0.000 abstract description 6
- 229940107187 fructooligosaccharide Drugs 0.000 abstract description 6
- 210000000936 intestine Anatomy 0.000 abstract description 5
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract description 4
- 230000035755 proliferation Effects 0.000 abstract description 4
- 206010010774 Constipation Diseases 0.000 abstract description 3
- 206010012735 Diarrhoea Diseases 0.000 abstract description 3
- 229910021529 ammonia Inorganic materials 0.000 abstract description 2
- 230000000968 intestinal effect Effects 0.000 abstract description 2
- 239000000203 mixture Substances 0.000 abstract description 2
- 239000000725 suspension Substances 0.000 abstract 1
- 241000186000 Bifidobacterium Species 0.000 description 9
- 241000193403 Clostridium Species 0.000 description 4
- 108010064851 Plant Proteins Proteins 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 235000021118 plant-derived protein Nutrition 0.000 description 3
- 108090000790 Enzymes Proteins 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 229930006000 Sucrose Natural products 0.000 description 2
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 2
- 208000002925 dental caries Diseases 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 2
- 239000005720 sucrose Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- TVEXGJYMHHTVKP-UHFFFAOYSA-N 6-oxabicyclo[3.2.1]oct-3-en-7-one Chemical compound C1C2C(=O)OC1C=CC2 TVEXGJYMHHTVKP-UHFFFAOYSA-N 0.000 description 1
- 244000291564 Allium cepa Species 0.000 description 1
- 235000002732 Allium cepa var. cepa Nutrition 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 244000077995 Coix lacryma jobi Species 0.000 description 1
- 235000007354 Coix lacryma jobi Nutrition 0.000 description 1
- RWSOTUBLDIXVET-UHFFFAOYSA-N Dihydrogen sulfide Chemical compound S RWSOTUBLDIXVET-UHFFFAOYSA-N 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 240000008620 Fagopyrum esculentum Species 0.000 description 1
- 235000009419 Fagopyrum esculentum Nutrition 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 229920001503 Glucan Polymers 0.000 description 1
- 108010042889 Inulosucrase Proteins 0.000 description 1
- 244000017020 Ipomoea batatas Species 0.000 description 1
- 235000002678 Ipomoea batatas Nutrition 0.000 description 1
- 208000007976 Ketosis Diseases 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 235000014633 carbohydrates Nutrition 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000008034 disappearance Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000000835 fiber Substances 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 229910000037 hydrogen sulfide Inorganic materials 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 150000002475 indoles Chemical class 0.000 description 1
- 235000014655 lactic acid Nutrition 0.000 description 1
- 239000004310 lactic acid Substances 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- JCQLYHFGKNRPGE-FCVZTGTOSA-N lactulose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 JCQLYHFGKNRPGE-FCVZTGTOSA-N 0.000 description 1
- 229960000511 lactulose Drugs 0.000 description 1
- PFCRQPBOOFTZGQ-UHFFFAOYSA-N lactulose keto form Natural products OCC(=O)C(O)C(C(O)CO)OC1OC(CO)C(O)C(O)C1O PFCRQPBOOFTZGQ-UHFFFAOYSA-N 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 150000002989 phenols Chemical class 0.000 description 1
- 231100000614 poison Toxicity 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 230000002747 voluntary effect Effects 0.000 description 1
Landscapes
- Beans For Foods Or Fodder (AREA)
Abstract
Description
【発明の詳細な説明】
本発明はフラクトオリゴ糖を含有した納豆製品に関する
。DETAILED DESCRIPTION OF THE INVENTION The present invention relates to natto products containing fructooligosaccharides.
古来、納豆は我が国において広く用いられて来た食品で
あり、最近になってその植物たん白質や植物せん維から
極めて健康維持、増進に優れた食品として注目を集め、
海外でも注目されるようになって来ている。Since ancient times, natto has been widely used in Japan, and recently it has attracted attention as a food that is extremely good for maintaining and promoting health due to its plant protein and fiber content.
It is also starting to attract attention overseas.
本発明者は、この納豆の有用性を高めるため人間の胎内
の有用菌であるビフィズス菌の繁殖を高め腐敗菌である
クロストリディウム・ベル７リンゲルス菌の繁殖を押え
ることを目的として本発明を発明した。In order to increase the usefulness of this natto, the present inventor has invented the present invention with the aim of increasing the proliferation of Bifidobacterium, which is a useful bacterium in the human womb, and suppressing the proliferation of Clostridium bell7 Ringers, which is a putrid bacterium. invented.
即ち、本発明はフラクトオリゴ糖を含有した納豆製品に
関する。That is, the present invention relates to natto products containing fructooligosaccharides.
本発明に用いられるフラクトオリゴ糖とは、ショ糖に７
ラクトーズが１〜３分子結合したものであって、■−ケ
トース（ｃｙｐ’ｔ ）、ニスドース（ＧＦａ）、ＩＦ
−フラクトフラノシルニストーＳＧＦ番）、又はこれら
の混合物である。ＧＦ、は分子式ＣＩ＋ Ｎｕ （Ｌ＠
、分子量５０４、ＧＦｍは分子式Ｃ菅４ Ｈ４ｔ Ｏｔ
＋、分子［６６６、Ｇ Ｆ ａは分子式Ｃ５ｏＨｓｙＯ
宜ａ、分子量８２８である。これらフラクトオリゴ糖は
自然界では広く高等植物に分布しており、例えば７スバ
ラガス、たまねぎ、きくいもなどに含まれて無害のもの
である。これらフラクトオリゴ糖は、工業的には７スペ
ルギルス属やオーレオノ２シディウム属に分類さ−れる
糸状菌の菌体中に生産されるフラクトース転移酵素をシ
、＄１に作用させることにより得られる。そして、この
糖はビフィズス菌を増殖させ、小腸内酵素等によっては
極めて分解されにく（従ってエネルギーになりにくく、
又虫歯の原因であるＳ、＝、−タンスによる不溶性グル
カンと乳酸との生成がショ糖に比べて極めて少ないので
虫歯になりにくい性質を有する。ビフィズス菌は人間の
腸内に生育する鮪の一種であるが、周知の如く、この菌
の減少又は消失はクロストリディウム・ベル７リンゲル
スなどの腐敗菌の増加をもたらし、胎内腐敗が高まり、
７ンモ二７、硫化水素、−アミン、フェノール、インド
ールその他の有毒物質が多量に生成され、これが宿主に
吸収されて、ますまず老化を早めることになり、その上
腸内ＰＨがアルカリ側圧傾けば腸内で生成されるアンモ
ニアの吸収が促進され、またアミノ酸脱脚酸酵素の活性
が高まり、アミンの生成が増加する。それ故人体のため
に腸内菌のバランスをビフィズス菌優勢、クロストリデ
ィウム・ベル７リンゲルスなどの有害菌劣勢とする必要
がある。フラクトオリゴ糖は前述の如く難消化性である
ため、これを摂取すると直接腸内に達し、これはビフィ
ズス菌の増殖をもたらすが一方ではクロストリディウム
・ベル７リンゲルスなどの有害菌の増殖を妨げる。この
事実は、従来ビフィズス菌増殖因子といわれてきたラク
ツロースがビフィズス菌を増殖させるが有害菌として代
表的なりｐストリゾイウム・ベル７リンゲルス等にもよ
（資化されることとは対照的であって、ラクッｐ−スよ
り７ラクトオリゴ糖が優れているといえる。The fructooligosaccharide used in the present invention is sucrose with 7
One to three molecules of lactose are bound together, including ■-ketose (cyp't), nisdose (GFa), and IF
-Fructofuranosylnisto SGF), or a mixture thereof. GF, has the molecular formula CI+ Nu (L@
, molecular weight 504, GFm has the molecular formula C Kan4 H4t Ot
+, molecule [666, G F a is the molecular formula C5oHsyO
The molecular weight is 828. These fructooligosaccharides are widely distributed in higher plants in the natural world, and are harmless, being contained in, for example, hexaspermica, onions, and sweet potatoes. These fructooligosaccharides are industrially obtained by reacting fructosyltransferase produced in the cells of filamentous fungi belonging to the genus Hexaspergillus and the genus Aureonosidium. This sugar causes bifidobacteria to proliferate and is extremely difficult to be broken down by enzymes in the small intestine (therefore, it is difficult to convert into energy.
In addition, since the production of insoluble glucan and lactic acid by S,=,-tance, which is the cause of dental caries, is extremely small compared to sucrose, it has the property of being less likely to cause dental caries. Bifidobacterium is a type of tuna that grows in the human intestine, and as is well known, the decrease or disappearance of this bacterium leads to an increase in putrefactive bacteria such as Clostridium ver.
7.Hydrogen sulfide, -amines, phenols, indoles, and other toxic substances are produced in large quantities, which are absorbed by the host, accelerating aging, and if the pH of the upper intestine tilts towards alkaline. The absorption of ammonia produced in the intestines is promoted, and the activity of amino acid delegating enzyme increases, increasing the production of amines. Therefore, for the sake of the human body, it is necessary to maintain a balance of intestinal bacteria in which Bifidobacterium is dominant and harmful bacteria such as Clostridium bell 7 ringers are negative. As mentioned above, fructooligosaccharides are indigestible, so when ingested, they reach the intestines directly, leading to the growth of Bifidobacteria, but on the other hand, preventing the growth of harmful bacteria such as Clostridium bell7 ringers. . This fact indicates that lactulose, which has traditionally been said to be a bifidobacteria growth factor, causes the growth of bifidobacteria, but it also causes the growth of bifidobacteria, which are representative of harmful bacteria such as P. It can be said that 7-lactooligosaccharide is superior to Lacpus.
本発明に用いられるフラクトオリゴ糖の量は、厳密を要
しないが、１日量として好ましくは１〜１２を最も好ま
しくは２〜８Ｐである。The amount of fructooligosaccharide used in the present invention is not strictly limited, but the daily amount is preferably 1 to 12, and most preferably 2 to 8.
本発明の納豆製品としては、従来の納豆が挙げられ例え
ば大豆それ自体、又は大豆にハトムギ、ソバ、フーン、
米、りｐレラ、カルシュウム、ビーナ、ンなどを加えた
ものを原料とし、これを蒸煮し、次に納豆菌を接種し、
発酵させたものがある。Examples of the natto product of the present invention include conventional natto, such as soybean itself, or soybean with adlay, buckwheat, hun, etc.
The raw material is rice, Riplera, calcium, beena, nug, etc., which is steamed and then inoculated with natto bacteria.
Some are fermented.
本発明の納豆製品に７ラクトオリゴ糖を加えるには、納
豆製品を製造する時のどの時点に加えてもよいが、納豆
菌を接種する際に、納豆菌液に混入して用いるのが操作
上都合が良い。In order to add 7-lactooligosaccharides to the natto products of the present invention, they may be added at any point during the production of the natto products, but for operational reasons it is best to mix them into the natto bacteria solution when inoculating the natto bacteria. convenient.
納豆製品に７ラクトオリゴ糖を添加すると糖質であるフ
ラクトオリゴ糖が納豆［より資化されてしまうのではな
いかと思われるが、以下の実験からそのようなことは認
められなかった。It is thought that adding 7-lactooligosaccharides to natto products may cause the fructooligosaccharides, which are carbohydrates, to be assimilated more than in natto, but this was not observed in the following experiment.
第１表
Ｗ 培地ニトリブトソイグイ冒ン培地「栄研」納豆Ｗｉ
：生菌数４．５Ｘ１０”〜
７５？ ）ｔ リボ１ｗ：ＧＦｔ ３５％＋ ＧＦｍ
５０Ｌ ＣＦ４１１％培養１７’ｏ、１７時間
従って、本発明の納豆製品では、フラクトオリゴ糖はど
んな時点に添加されても納豆菌により資化されず、食用
に供することができる。Table 1 W Medium Nitributo Soigui Incubation Medium “Eiken” Natto Wi
:Number of viable bacteria 4.5X10"~75?)t Ribo 1w: GFt 35% + GFm
50L CF4 11% culture 17'o, 17 hours Therefore, in the natto product of the present invention, fructooligosaccharide is not assimilated by Bacillus natto no matter what time it is added and can be used for food.
本発明の納豆製品は、食するとビフィズス菌の繁殖を促
進し、それにより胎内腐敗の抑制、便秘・下痢の改善な
どの人体にとり有用な作用をもたらす。When eaten, the natto product of the present invention promotes the proliferation of bifidobacteria, thereby producing beneficial effects on the human body such as suppressing in-utero putrefaction and improving constipation and diarrhea.
フラクトオリゴ糖は、異味・異臭は全くなく、熱安定性
（１４０’０まで安定、メイラード反応なし）やＰＨ安
定性（ＰＨ６以上では、１２０°０で安定）Ｋ優れ、納
豆製品に含有されても納豆製品の品質に悪影蕃を及ぼす
ことがない。又、毒性もなく、人体に何も影響しな（１
゜
次に実施例を示す。Fructooligosaccharide has no off-taste or odor, and has excellent thermal stability (stable up to 140'0, no Maillard reaction) and pH stability (stable at 120°0 at pH 6 or above), so even if it is contained in natto products. There is no negative effect on the quality of natto products. Also, it is non-toxic and has no effect on the human body (1).
゜Examples will now be shown.
実施例１
大豆６０ユを秤取し、水潰して吸水させて２．２倍量と
し、これを蒸−、鬼した。Example 1 60 units of soybeans were weighed out and crushed in water to absorb water to make 2.2 times the volume, which was then steamed and boiled.
お旋納豆菌液５俣（生菌数４．５ Ｘ １０ｎ／ｄ ）
に、フラクトオリゴ糖（ｑＥＩ３５％、ＧＦｓ５０％、
ＧＦａｌ１％）４ＫＦを加え、常法により納豆を作った
。5 bags of natto bacteria solution (number of viable bacteria 4.5 x 10n/d)
, fructooligosaccharides (qEI 35%, GFs 50%,
GFal 1%) 4KF was added and natto was made by a conventional method.
出来上った納豆１００を中には釣４Ｆの７ラクトオリゴ
糖を含有した。The resulting natto 100 contained 7 lactooligosaccharides of Tsuri 4F.
この納豆を食べると、胎内の腐敗が抑えられ、便秘・下
痢の症状が改善された。Eating this natto suppressed decomposition in the womb and improved symptoms of constipation and diarrhea.
特許出願人 全国植物蛋白協同組合
手続補正書（自発）
昭和５９年９月、！θ日
１ 事件の表示 昭和５８年特許願第２４２１２６号２
、発明の名称 新規な納豆製品
３、補正をする者
事件との関係 特許出願人
トク々ヨウトプンキョクク七／ダ キ
住 所 東京都文京区千駄木２−４８−８ゼンコクショ
クプノタンパクキョウドウクミ アイ塩 称 全国植物
蛋白協同組合
４、補正の対象
明細書の発明の詳細な説明の欄
５、補正の内容
（１）明細書第４ページ下から第７行と下から第８行と
の間に以下の文をそう人する。Patent applicant: National Plant Protein Cooperative Association procedural amendment (voluntary) September 1982,! θ Day 1 Display of incident 1982 Patent Application No. 242126 2
, Title of the invention Novel natto product 3, Relationship with the case of the person making the amendment Patent applicant Tokusyoto Punkyokukuku 7/Daki Address 2-48-8 Sendagi, Bunkyo-ku, Tokyo Salt Name National Plant Protein Cooperative Association 4, Detailed explanation of the invention column 5 of the specification subject to amendment, Contents of amendment (1) Between the 7th line from the bottom and the 8th line from the bottom of page 4 of the specification Let's say the following sentences.
Claims (1)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58242126A JPS60133852A (en) | 1983-12-23 | 1983-12-23 | Novel natto (fermented soybean) product |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58242126A JPS60133852A (en) | 1983-12-23 | 1983-12-23 | Novel natto (fermented soybean) product |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS60133852A true JPS60133852A (en) | 1985-07-17 |
| JPH0244500B2 JPH0244500B2 (en) | 1990-10-04 |
Family
ID=17084683
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP58242126A Granted JPS60133852A (en) | 1983-12-23 | 1983-12-23 | Novel natto (fermented soybean) product |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS60133852A (en) |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01281074A (en) * | 1988-05-06 | 1989-11-13 | Gold Kosan Kk | Multiplication treatment of cell to form kneaded bond |
| WO1997002829A3 (en) * | 1995-07-11 | 1997-03-27 | Abbott Lab | Use of indigestible oligosaccharides to prevent and treat diarrhea |
| WO2007043563A1 (en) * | 2005-10-13 | 2007-04-19 | Meiji Seika Kaisha, Ltd. | Composition for improving intestinal flora |
| EP1505989A4 (en) * | 2002-05-20 | 2007-05-09 | Cedars Sinai Medical Center | MANIPULATION OF THE SPEED OF GASTROINTESTINAL TRANSIT BY MODULATION OF INTESTINAL METHANE CONCENTRATION |
| US9744208B2 (en) | 2013-03-15 | 2017-08-29 | Cedars-Sinai Medical Center | Methods of diagnosis, selection, and treatment of diseases and conditions caused by or associated with methanogens |
| US9845511B2 (en) | 2013-03-15 | 2017-12-19 | Cedars-Sinai Medical Center | Methods of diagnosis, selection, and treatment of diseases and conditions caused by or associated with methanogens |
| US9956292B2 (en) | 2014-08-13 | 2018-05-01 | Cedars-Sinai Medical Center | Anti-methanogenic compositions and uses thereof |
| US10066254B2 (en) | 2002-05-20 | 2018-09-04 | Cedars-Sinai Medical Center | Diagnosis of constipation by analysis of methane concentration |
| JP2020503034A (en) * | 2016-12-27 | 2020-01-30 | ヒルズ・ペット・ニュートリシャン・インコーポレーテッド | Pet food composition and method |
| JP2020070245A (en) * | 2018-10-30 | 2020-05-07 | 物産フードサイエンス株式会社 | Agents for controlling number of ruminococcus bacteria |
| US10736871B2 (en) | 2015-04-01 | 2020-08-11 | Cedars-Sinai Medical Center | Anti-methanogenic lovastatin analogs or derivatives and uses thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5894363A (en) * | 1981-12-01 | 1983-06-04 | Zenkoku Shokubutsu Tanpaku Shokuhin Kyodo Kumiai | Novel natto product |
| JPS58201980A (en) * | 1982-05-19 | 1983-11-25 | Meiji Seika Kaisha Ltd | Substance for promoting propagation of lactobacillus bifidus |
-
1983
- 1983-12-23 JP JP58242126A patent/JPS60133852A/en active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5894363A (en) * | 1981-12-01 | 1983-06-04 | Zenkoku Shokubutsu Tanpaku Shokuhin Kyodo Kumiai | Novel natto product |
| JPS58201980A (en) * | 1982-05-19 | 1983-11-25 | Meiji Seika Kaisha Ltd | Substance for promoting propagation of lactobacillus bifidus |
Cited By (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01281074A (en) * | 1988-05-06 | 1989-11-13 | Gold Kosan Kk | Multiplication treatment of cell to form kneaded bond |
| WO1997002829A3 (en) * | 1995-07-11 | 1997-03-27 | Abbott Lab | Use of indigestible oligosaccharides to prevent and treat diarrhea |
| US10066254B2 (en) | 2002-05-20 | 2018-09-04 | Cedars-Sinai Medical Center | Diagnosis of constipation by analysis of methane concentration |
| EP1505989A4 (en) * | 2002-05-20 | 2007-05-09 | Cedars Sinai Medical Center | MANIPULATION OF THE SPEED OF GASTROINTESTINAL TRANSIT BY MODULATION OF INTESTINAL METHANE CONCENTRATION |
| EP2251017A1 (en) * | 2002-05-20 | 2010-11-17 | Cedars-Sinai Medical Center | Manipulation of the rate of gastrointestinal transit by modulating intestinal methane concentration |
| US9066962B2 (en) | 2002-05-20 | 2015-06-30 | Cedars-Sinai Medical Center | Method of using a probiotic microorganism for the treatment of diarrhea |
| US9192618B2 (en) | 2002-05-20 | 2015-11-24 | Cedars-Sinai Medical Center | Method of treating constipation-predominant irritable bowel syndrome |
| US10844417B2 (en) | 2002-05-20 | 2020-11-24 | Cedars-Sinai Medical Center | Method of distinguishing constipation predominant IBS from inflammatory bowel syndrome by analysis of methane concentration |
| US9358245B2 (en) | 2002-05-20 | 2016-06-07 | Cedars-Sinai Medical Center | Method of treating constipation |
| JPWO2007043563A1 (en) * | 2005-10-13 | 2009-04-16 | 明治製菓株式会社 | Composition for improving intestinal flora |
| WO2007043563A1 (en) * | 2005-10-13 | 2007-04-19 | Meiji Seika Kaisha, Ltd. | Composition for improving intestinal flora |
| US10226505B2 (en) | 2013-03-15 | 2019-03-12 | Cedars-Sinai Medical Center | Methods of diagnosis, selection, and treatment of diseases and conditions caused by or associated with methanogens |
| US9744208B2 (en) | 2013-03-15 | 2017-08-29 | Cedars-Sinai Medical Center | Methods of diagnosis, selection, and treatment of diseases and conditions caused by or associated with methanogens |
| US9845511B2 (en) | 2013-03-15 | 2017-12-19 | Cedars-Sinai Medical Center | Methods of diagnosis, selection, and treatment of diseases and conditions caused by or associated with methanogens |
| US12071673B2 (en) | 2013-03-15 | 2024-08-27 | Cedars-Sinai Medical Center | Methods of diagnosis, selection, and treatment of diseases and conditions caused by or associated with methanogens |
| US10519515B2 (en) | 2013-03-15 | 2019-12-31 | Cedars-Sinai Medical Center | Methods of diagnosis, selection, and treatment of diseases and conditions caused by or associated with methanogens |
| US10688149B2 (en) | 2013-03-15 | 2020-06-23 | Cedars-Sinai Medical Center | Methods of diagnosis, selection, and treatment of diseases and conditions caused by or associated with methanogens |
| US10328151B2 (en) | 2014-08-13 | 2019-06-25 | Cedars-Sinai Medical Center | Anti-methanogenic compositions and uses thereof |
| US9956292B2 (en) | 2014-08-13 | 2018-05-01 | Cedars-Sinai Medical Center | Anti-methanogenic compositions and uses thereof |
| US11344501B2 (en) | 2014-08-13 | 2022-05-31 | Cedars-Sinai Medical Center | Anti-methanogenic compositions and uses thereof |
| US10668159B2 (en) | 2014-08-13 | 2020-06-02 | Cedars-Sinai Medical Center | Anti-methanogenic compositions and uses thereof |
| US10736871B2 (en) | 2015-04-01 | 2020-08-11 | Cedars-Sinai Medical Center | Anti-methanogenic lovastatin analogs or derivatives and uses thereof |
| JP2020503034A (en) * | 2016-12-27 | 2020-01-30 | ヒルズ・ペット・ニュートリシャン・インコーポレーテッド | Pet food composition and method |
| JP2021118741A (en) * | 2016-12-27 | 2021-08-12 | ヒルズ・ペット・ニュートリシャン・インコーポレーテッド | Pet food compositions and methods for the same |
| US12096782B2 (en) | 2016-12-27 | 2024-09-24 | Hill's Pet Nutrition, Inc. | Pet food compositions and methods for the same |
| JP2020070245A (en) * | 2018-10-30 | 2020-05-07 | 物産フードサイエンス株式会社 | Agents for controlling number of ruminococcus bacteria |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0244500B2 (en) | 1990-10-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TW421673B (en) | Trehalose-releasing enzyme, and its preparation and uses | |
| KR100436355B1 (en) | THE METHOD OF PREPARING DRINK BY FURMENTATION CONTAINNING MUCH INGREDIENT OF ANTIOXIDANT MATERIAL, OCTACOSANOL, β-1,3 GLUCAN AND IT'S PRODUCT | |
| JPS60133852A (en) | Novel natto (fermented soybean) product | |
| JP2549638B2 (en) | Bifidobacterium growth promoting composition | |
| JP2004187501A (en) | Food material highly containing gamma-aminobutyric acid and method for producing the same | |
| JPS5953834B2 (en) | Bifidobacterium growth promoter | |
| AU2007302899B2 (en) | Pre-fermented symbiotic matrix based on a cereal suspension with encapsulated probiotics, manufacture process and corresponding utilization | |
| JP2018082700A (en) | Prebiotic composition for enhancing stability of Lactobacillus strains and method for enhancing stability using the same | |
| Arrizón et al. | Production and bioactivity of fructan‐type oligosaccharides | |
| CN105176870B (en) | A kind of method that solid fermentation produces feeding bacillus coagulans | |
| CN107041529A (en) | A kind of Xinhui citrus reticulata fruit lactic acid ferment juice and preparation method thereof | |
| JP6955808B1 (en) | How to make fermented honey | |
| CN105199939A (en) | Preparation method of vinegar having low trimethylamine acetate content and rich konjac high-F-ratio oligopeptide | |
| JP2005312438A (en) | FOOD MATERIAL WITH HIGH gamma-AMINOBUTYRIC ACID CONTENT AND METHOD FOR PRODUCING THE SAME | |
| CN108813044A (en) | A kind of preparation method of pectase honey citron tea | |
| CN108813586A (en) | A kind of weight reducing ferment generation meal packet and preparation method thereof containing small-molecular peptides and prebiotics | |
| JPH0421461B2 (en) | ||
| CN107794160A (en) | A kind of corn gluten protein liquid and preparation method thereof | |
| CN108813045A (en) | A kind of preparation method of pectase honey lemon tea | |
| JP7493742B2 (en) | Utilization of fermentation products produced by Bacillus bacteria and related species | |
| JP3173805B2 (en) | Fructooligosaccharide-containing syrup and method for producing the same | |
| CN107198219A (en) | A kind of preparation method of the food additives of the polyglutamic acid containing γ | |
| JP2003235492A (en) | Natto and its production method | |
| CN116250605B (en) | A burdock solid beverage rich in type I difructose anhydride, inulin and oligofructose | |
| CN107518277A (en) | A kind of preparation technology of wild rice ground rice |