JPS58216109A - Dried film cosmetic and laminated film cosmetic - Google Patents

Abstract

PURPOSE:To prepare the titled cosmetic capable of keeping a component which is extremely unstable in water with little decomposition and deactivation with time, by adding a drug component or a cosmetic component to a base composed mainly of a film-forming water-soluble polymer and water, and forming the mixture to a film. CONSTITUTION:A vehicle selected from film-forming water-soluble polymers (preferably alpha-1,6-maltotriol) is mixed with water at a ratio of (5-25):(95-75), and a drug component or a cosmetic component (e.g. ascorbic acid, enzyme, etc.) is dissolved or dispersed in the solution to obtain a pasty composition, which is formed to a thin film by casting, and dried to obtain a dried film cosmetic having a thickness of 50-200mu. As an alternative, the composition is applied uniformly to a substrate (the thickness of the applied film is preferably 10-several tens microns) and dried to obtain a laminate film cosmetic having a thickness of 50-200mu. The amount of ascorbic acid and enzyme in the dried final product are preferably 0.5-2% and 0.02-0.5%, respectively.

Description

DETAILED DESCRIPTION OF THE INVENTION The present invention relates to a novel cosmetic, specifically ascorbic
The present invention relates to a drying film-like cosmetic and a laminated film-like cosmetic that are formulated with rtRs, enzymes, and other treatment ingredients or skin-beautifying ingredients in a stabilized state.

Conventionally, ascorbic acid is extremely unstable to heat and light and easily oxidized, and even when used as a base component of cosmetics, it does not lose its VO activity over time and cannot exert its original effects. This tendency is particularly noticeable in cosmetics containing a large amount of water, which causes abnormal changes and unpleasant odors due to decomposition, making them undesirable as products. For this reason, attempts have been made to stabilize it by various derivatizations such as higher fatty acids and phosphoric acid, but at present the objective has not yet been fully achieved. In addition, some attempts have been made to stabilize the product by packaging it in powder form, but this also requires mixing with water and lotion before use, which is extremely complicated and is not ideal. Similarly, enzymes have low stability against heat, limited pH range, etc., and are easily deactivated in ordinary cosmetics. 'As an improvement on this, there is a form in which some microcapsules are used.
This substance is easily deactivated in the presence of other cosmetic raw materials, so it is not yet in a state where it can be used in cosmetics.

The present inventor has solved the above-mentioned drawbacks in the stability of ascorbic acids and # elements, and has completed a novel drying film-like cosmetic and a laminated film-like cosmetic that has an easy-to-use form. .

That is, the present invention provides a thin film of a paste composition in which at least one or more of medicinal ingredients or skin-beautifying ingredients are blended into a base mainly consisting of water and a water bathable polymer having film-forming ability. , the thickness of the dried film is 1
The present invention relates to a drying film-like cosmetic having a particle size of 0 μm to 1 μm.

Furthermore, the present invention is characterized in that at least one or two or more medicinal ingredients or skin-beautifying ingredients selected from ascorbic acids or enzymes are blended into a base mainly consisting of water and a water-soluble polymer having film-forming ability. It also relates to a laminated film-like cosmetic product characterized by uniformly applying a paste composition to a holder to form a thin film and drying it to form a laminate with a thickness of 50μ to 20μ. .

Excipients that are water-soluble polymers that can be applied to the present invention include starches, mannan, galactan, sodium alginate, dextran (α-1,6-glycoside), α-1
, 6-maltotriose, gelatin, casein, etc., natural water-soluble polymers, methylcellulose, ethylcellulose, hydroxyethylcellulose, carboxymethylcellulose, etc., and other semisynthetic water-soluble polymers, polyvinyl alcohol, sodium polyacrylate, There are synthetic water bathable polymers such as polyethylene oxide, but the solubility of the excipient itself in water at low temperatures, ascorbic acids in the base, the dispersion stability of enzymes, and the safety of the excipient itself are important. and considering the film forming ability h4 during thinning, α-1,6-
Maltotriose is preferred.

In addition, medicinal ingredients or skin-beautifying ingredients that are blended into the base include ascorbic acids, more specifically ascorbic acids,
Ascorbic acid sodium, potassium, calcium,
Salts of magnesium, etc., phosphoric acid of the 2- or 3-position hydroxyl group of ascorbic acid, acetic acid, lauric acid, nosorumitic acid,
Examples include various Nisthyl derivatives such as stearic acid, which are blended in the form of solution or dispersion, and examples of enzymes include protease as a protein enzyme, and souse as a hydrolytic enzyme.

- The selected ascorbic acids or 1 [R is 1a or two or more of ascorbic acids alone or,
One or more enzymes may be used alone, or one or more ascorbic acids and one or more enzymes may be combined. As for the blending amount, the final content of ascorbic acids can be in the range of α1 to 10 for the dry film □, taking into account the effectiveness, but taking into consideration the optimal effect expression 5- This is preferably in the range of 0.5 to 2% based on the dry film, as it is efficient and effective.

Similarly, #I is 0.01 to 0.01 to the dry film.
Although it is possible to combine the west as the effective range of 6chi,
Normal cosmetics) and dry film are 102~t1.
A range of 5% is ideal.

Application of the selected ascorbic acids and enzymes is dissolved or dispersed in a base mainly consisting of an excipient selected from the water-soluble polymer group and water. , a pasty composition is obtained. At this time, the mixing ratio of excipient and water is 1 to 50% excipient to 1. Although 99 to 50% water is possible, in consideration of viscosity, ease of handling during film formation, etc., a ratio of 12 to 25% excipient and 95 to 75% water is preferred. The polished -2-su]-like composition is formed into a thin film by a casting method or the like, and dried under reduced pressure at about 40° C. or lower. The thickness of the thin film obtained here maintains flexibility and extensibility.
- 10 μ to 111 Ill+ considering each bonito membrane once
Preferably. Similarly, the burst composition is paper-cast onto a flexible holder made of paper, glassy 1,15-ethylene, polypropylene-6-ethylene, polyester, acetyl cellulose, etc. The composition is uniformly coated by a coating method such as a dip coater method, a roll coater method, a knife coater method, etc., and dried under reduced pressure at about 40° C. or lower to form a thin film. At this time, the thickness of the holder is preferably 50 to 200 microns in order to maintain flexibility and film strength, and the optimal thickness of the coated thin film is 10 to needle micro.

The dry film-like cosmetics and laminated film-like cosmetics obtained as described above do not contain much water, and therefore ascorbic acids and enzymes, which are extremely unstable in aqueous systems, may deteriorate over time. It can exist stably without being decomposed or deactivated.

In addition, during use, after applying water or lotion to the face, etc., divide the film-like cosmetic, normal film-like cosmetic, or laminated film-like cosmetic into arbitrary shapes as needed, and paste it on the face, etc. wear. At this time, the water or the water in the lotion dissolves the thin film containing ascorbic acids or enzymes, and the ascorbic acids or enzymes contained therein exhibit the desired effect.

Next, examples of representative arrangement devices and methods of the present invention will be shown.

Example 1.7 Dry membranous cosmetic containing Scorbine #R 20 parts of α-1,6-maltotriose was dispersed in 80 parts of water, and the mixture was heated to 60°C to completely dissolve it. Cooling was maintained slowly to below 40°C. Separately, 0.2 part of ascorbic acid was stirred and dissolved in 20 parts of water to prepare a solution, which was mixed little by little into the base to obtain a starch composition. Next, this cast composition was poured onto a stainless steel belt-tall drum, and then dried under reduced pressure at a temperature below about 40 DEG C. to obtain a dry film-like cosmetic. The dry filmy cosmetic obtained here contains ascorbic acid at a ratio of 1% to the dry film. Further, the film thickness is controlled by the resin content in the base and the viscosity derived from the molecular weight of the resin itself.

Example 2. EXAMPLE 1 A drying film-like cosmetic containing lysate 5 parts of α-1,6-maltotriose was dissolved in 95 parts of water. Separately, a solution of 1,005 parts of lipase dissolved in 10 parts of water was prepared, and this was mixed into the base little by little to obtain a starch composition. Thereafter, a dry film-like cosmetic was obtained in the same manner as in Example 1. The resulting dry film cosmetic contains lipase at a ratio of 0.1% to the dry film.

Example 6. Disperse 15 parts of α-1,6-maltotriose, a laminated film cosmetic containing sodium ascorbate and protease, in 85 parts of water, heat to 60°C to completely dissolve 2, and cool to 40°C or below. Maintained. Separately, a solution was prepared in which 0.1 part of sodium ascorbate and 0.02 part of protease were dissolved in 20 parts of water, and this was mixed into the base little by little to obtain a burst-like composition. . Next, this paste-like as-prepared product was coated with a thickness of 80 μm and a small amount of silicone release agent 9
A knife coater or a roll coater was used to uniformly coat the polyester retention film coated with -. Then, it was slowly dried under reduced pressure below 40"C to obtain MJi
1 film-like 11'', cosmetic f was obtained.

The drying film-like cosmetic or laminated film-like cosmetic according to the present invention is prepared by adding 1.0% to water to a water-soluble polymer bare hand 4 that does not contain much water. Since this method confines unstable ascorbic acids and enzyme X, the stability is extremely high.
fL Cd! When in use, it is extremely convenient because it can be used in any size.

Next, comparative data will be shown regarding the stability of the dry film cosmetic containing ascorbic acids or enzymes according to the present invention and ascorbic acids or enzymes alone.

As a test method 7, for scorbic acids, dry film cosmetics (Example 1) and aqueous solutions formulated at the same concentration (1%), and for enzymes, 4fit ([1%
, 1% concentration) and rapidly drying film-like cosmetics (Implementation I
The ascorbic acid decomposition rate and the liver-10-ase deactivation rate were compared for several ff1tJ at 40°C for 2 weeks for J'lJ2) and aqueous solutions. Here, the ascorbic acid decomposition rate is determined by measuring the residual amount of ascorbic acid using high performance liquid chromatography, and the lipase deactivation rate is determined by measuring the amount of free fatty acids obtained using olive oil as a substrate using gas chromatography. The measured values were back calculated. The results are shown in Table 1.

Table 1 Comparative Data on Ascorbic Acid and Enzyme Stability As is clear from Table 1, the stability of the ascorbic acid and enzyme blended in the film-like cosmetics obtained in the present invention is extremely high.

As mentioned above, in the drying film cosmetic and laminated film cosmetic according to the present invention, ascorbic acids,
The stability of the enzyme is extremely high, and the cosmetic is formulated in such a way that it can be fully effective when used, and it is extremely convenient as the user can divide it into the desired size and use it. It is an excellent cosmetic.

Patent applicant: POLA CHEMICAL INDUSTRIES, INC.

Claims (1)

[Scope of Claims] 1. A paste composition containing at least one or two or more of medicinal ingredients or beautifying ingredients in a base mainly consisting of water and a water-soluble polymer having film-forming ability is made into a thin film. A drying film-like cosmetic having a film thickness of 10μ to 1−1 after drying. 2. At least one or two or more medicinal ingredients or skin-beautifying ingredients selected from ascorbic acid li% shikke enzyme are blended into a base mainly consisting of water and a water-soluble polymer with film-forming ability. A laminated film cosmetic comprising a paste composition uniformly applied to a holder to form a thin film and dried to form a laminate with a thickness of 50 μm to 200 μm. 3. The drying film-like cosmetic according to claim 1, wherein the water-soluble polymer is α-1,6-maltotriose, and the laminated film-like cosmetic according to claim 2, wherein the desired range is %fFmf4.