JPS5780368A - Preparation of tryptophan and its derivative - Google Patents
Preparation of tryptophan and its derivativeInfo
- Publication number
- JPS5780368A JPS5780368A JP15595880A JP15595880A JPS5780368A JP S5780368 A JPS5780368 A JP S5780368A JP 15595880 A JP15595880 A JP 15595880A JP 15595880 A JP15595880 A JP 15595880A JP S5780368 A JPS5780368 A JP S5780368A
- Authority
- JP
- Japan
- Prior art keywords
- tryptophan
- derivative
- formula
- raw material
- expressed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Indole Compounds (AREA)
Abstract
PURPOSE: To obtain a tryptophan derivative chemically and particularly microbiologically convertible into L-tryptophan industrially and advantageously, by hydrolyzing an N-(substituted methylene)tryptophan ester derivative as a raw material under acidic conditions.
CONSTITUTION: An N-(substituted methylene)tryptophan ester derivative expressed by formula I[R1 is H, lower alkyl or (un)substituted aryl; R2 is (un) substituted aryl; R3 is lower alkyl]as a raw material is hydrolyzed under acidic conditions, e.g. hydrochloric or acetic acid, to prepare a tryptophan derivative expressed by formula II. The resultant compound expressed by formula II is then hydrolyzed in the presence of a base, e.g. sodium hydroxide, to afford tryptophan and treated by a microorganism to give L-tryptophan easily without passing through many troublesome steps. By-products formed in preparing the tryptophan are reusable as the starting raw material.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15595880A JPS5780368A (en) | 1980-11-07 | 1980-11-07 | Preparation of tryptophan and its derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15595880A JPS5780368A (en) | 1980-11-07 | 1980-11-07 | Preparation of tryptophan and its derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5780368A true JPS5780368A (en) | 1982-05-19 |
Family
ID=15617245
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP15595880A Pending JPS5780368A (en) | 1980-11-07 | 1980-11-07 | Preparation of tryptophan and its derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5780368A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5214141A (en) * | 1991-01-18 | 1993-05-25 | Fuji Photo Film Co., Ltd. | Azomethine compound and photographic dye comprising the azomethine compound |
-
1980
- 1980-11-07 JP JP15595880A patent/JPS5780368A/en active Pending
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5214141A (en) * | 1991-01-18 | 1993-05-25 | Fuji Photo Film Co., Ltd. | Azomethine compound and photographic dye comprising the azomethine compound |
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