[go: up one dir, main page]

JPS5775998A - Preparation of cytidine diphosphate choline ester - Google Patents

Preparation of cytidine diphosphate choline ester

Info

Publication number
JPS5775998A
JPS5775998A JP15140480A JP15140480A JPS5775998A JP S5775998 A JPS5775998 A JP S5775998A JP 15140480 A JP15140480 A JP 15140480A JP 15140480 A JP15140480 A JP 15140480A JP S5775998 A JPS5775998 A JP S5775998A
Authority
JP
Japan
Prior art keywords
phosphorylcholine
cytidine
preparation
1mol
pref
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP15140480A
Other languages
Japanese (ja)
Inventor
Osamu Maruyama
Tadashi Sato
Takeshi Kawashima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kohjin Holdings Co Ltd
Kojin Co Ltd
Original Assignee
Kohjin Holdings Co Ltd
Kojin Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kohjin Holdings Co Ltd, Kojin Co Ltd filed Critical Kohjin Holdings Co Ltd
Priority to JP15140480A priority Critical patent/JPS5775998A/en
Publication of JPS5775998A publication Critical patent/JPS5775998A/en
Pending legal-status Critical Current

Links

Landscapes

  • Saccharide Compounds (AREA)

Abstract

PURPOSE: To prepare the titled compound useful as a remedy for obnubilation caused by brain lesion, economically, in an industrial scale, by condensing cytidine- 5'-phosphate with a metal salt of phosphorylcholine halide in the presence of a specific amount of cyanuric chloride.
CONSTITUTION: The objective compound can be obtained by condensing (A) cytidine-5'-phosphate with (B) a metal salt of phosphorylcholine halide (e.g. calcium salt of phosphorylcholine chloride) in the presence of ≥1mol, pref. 2W4mol, based on 1mol of the component B, of cyanuric chloride, pref. in an organic solvent such as dimethylformamide, etc., e.g. at 0W40°C for 1hr.
EFFECT: The objective compound can be prepared with a simple process, in high yield, without using expensive reagents.
COPYRIGHT: (C)1982,JPO&Japio
JP15140480A 1980-10-30 1980-10-30 Preparation of cytidine diphosphate choline ester Pending JPS5775998A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP15140480A JPS5775998A (en) 1980-10-30 1980-10-30 Preparation of cytidine diphosphate choline ester

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15140480A JPS5775998A (en) 1980-10-30 1980-10-30 Preparation of cytidine diphosphate choline ester

Publications (1)

Publication Number Publication Date
JPS5775998A true JPS5775998A (en) 1982-05-12

Family

ID=15517842

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15140480A Pending JPS5775998A (en) 1980-10-30 1980-10-30 Preparation of cytidine diphosphate choline ester

Country Status (1)

Country Link
JP (1) JPS5775998A (en)

Similar Documents

Publication Publication Date Title
JPS5329912A (en) Preparation of sterol-glycosides from vegetable material
OA08106A (en) Process for the preparation of potassium chloride having a weight percentage of K2O greater than 55% from the fine decomposition salt of carallite.
JPS5775998A (en) Preparation of cytidine diphosphate choline ester
JPS5775999A (en) Preparation of cytidine diphosphate choline ester
JPS5775997A (en) Preparation of cytidine diphosphate choline ester
JPS53107485A (en) Preparation of s-adenosyl-l-methionine salt
JPS5437096A (en) Method of procucing pure phosphoric acid
JPS5677298A (en) Movel 5-fluorouridine derivative and its preparation
SU810699A1 (en) Method of preparing 2,5-dimethyl-7-chloroxazolo/5,4-d/pyrimine
JPS5427582A (en) Preparation of dinucleoside triphosphate
JPS51149287A (en) Process for preparing 5-fluorouracil
JPS57108099A (en) Preparation of choline cytidine diphosphate
JPS5433997A (en) Concentrating method of tritium
JPS5266531A (en) Preparation of oxazolylethylene compounds
DK632187A (en) NEW IMPROVED PROCEDURE FOR PENICILLAN ACID DERIVATIVES
JPS5711998A (en) Novel adenosine phosphate compound and its salt
JPS54157566A (en) Preparation of nucleoside
JPS5239699A (en) Improved methods of producing adenosine derivatives
JPS5241293A (en) Method of manufacturing glucose-1-phosphate and glucose-6-phosphate
JPS53101323A (en) Preparation of 2-substd-2-sulfenyl-1,3-dicarbonyl copound
JPS5594399A (en) Pyrimidine-nucleoside derivative
SE8105338L (en) NEW SET TO MAKE APOVINCAMIC ACID ESTERS
JPS53119882A (en) Preparation of aminopyrazinecarboxylic acid esters
JPS5278853A (en) Preparation of arylphosphonic dichlorides
JPS52113922A (en) Anticorrosives for apparatus of acrylonitrile preparation