JPS5770820A - Immunoregulating agent - Google Patents
Immunoregulating agentInfo
- Publication number
- JPS5770820A JPS5770820A JP14571580A JP14571580A JPS5770820A JP S5770820 A JPS5770820 A JP S5770820A JP 14571580 A JP14571580 A JP 14571580A JP 14571580 A JP14571580 A JP 14571580A JP S5770820 A JPS5770820 A JP S5770820A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- group
- remedy
- diseases
- immunity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000004957 immunoregulator effect Effects 0.000 title abstract 3
- 230000036039 immunity Effects 0.000 abstract 3
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 230000005856 abnormality Effects 0.000 abstract 2
- 201000011510 cancer Diseases 0.000 abstract 2
- 201000010099 disease Diseases 0.000 abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 208000023275 Autoimmune disease Diseases 0.000 abstract 1
- 208000027932 Collagen disease Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000005640 glucopyranosyl group Chemical group 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 201000003068 rheumatic fever Diseases 0.000 abstract 1
- 230000001629 suppression Effects 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
Landscapes
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PURPOSE: To provide an immunoregulating agent containing a glucopyranosyl derivative.
CONSTITUTION: An immunoregulating agent containing the compound of formula I[R1 is H or -CH2OH; R2 is -NH-CS-NH-R3 (R3 is group of formula II, group of formula II, group of formula III, etc.), group of formula IV, etc.] e.g. N-(β-D-gluco- pyranosyl)-N'-(6-amino-1,3-dimethyl-2,4-dioxopyrimidin-5-yl) thioureide. The agent is useful for the remedy of diseases caused by the abnormality in immunity funtion or diseases accompanied by the abnormality of immunity function (e.g. remedy of cancer, prevention of metastatis of cancer, immunity suppression for transplantation of organs, remedy for collagen diseases and autoimmune diseases such as rheumatic arthritis, etc.).
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14571580A JPS5770820A (en) | 1980-10-20 | 1980-10-20 | Immunoregulating agent |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP14571580A JPS5770820A (en) | 1980-10-20 | 1980-10-20 | Immunoregulating agent |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5770820A true JPS5770820A (en) | 1982-05-01 |
JPS6310924B2 JPS6310924B2 (en) | 1988-03-10 |
Family
ID=15391444
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP14571580A Granted JPS5770820A (en) | 1980-10-20 | 1980-10-20 | Immunoregulating agent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5770820A (en) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8362055B2 (en) | 2004-11-18 | 2013-01-29 | Synta Pharmaceuticals, Inc. | Triazole compounds that modulate HSP90 activity |
US9205086B2 (en) | 2010-04-19 | 2015-12-08 | Synta Pharmaceuticals Corp. | Cancer therapy using a combination of a Hsp90 inhibitory compounds and a EGFR inhibitor |
US9402831B2 (en) | 2011-11-14 | 2016-08-02 | Synta Pharmaceutical Corp. | Combination therapy of HSP90 inhibitors with BRAF inhibitors |
US9439899B2 (en) | 2011-11-02 | 2016-09-13 | Synta Pharmaceuticals Corp. | Cancer therapy using a combination of HSP90 inhibitors with topoisomerase I inhibitors |
US10500193B2 (en) | 2011-11-02 | 2019-12-10 | Synta Pharmaceuticals Corporation | Combination therapy of HSP90 inhibitors with platinum-containing agents |
-
1980
- 1980-10-20 JP JP14571580A patent/JPS5770820A/en active Granted
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8362055B2 (en) | 2004-11-18 | 2013-01-29 | Synta Pharmaceuticals, Inc. | Triazole compounds that modulate HSP90 activity |
US8901308B2 (en) | 2004-11-18 | 2014-12-02 | Synta Pharmaceuticals Corp. | Triazole compounds that modulate Hsp90 activity |
US9090569B2 (en) | 2004-11-18 | 2015-07-28 | Synta Pharmaceuticals Corp. | Triazone compounds that modulate HSP90 activity |
US9205086B2 (en) | 2010-04-19 | 2015-12-08 | Synta Pharmaceuticals Corp. | Cancer therapy using a combination of a Hsp90 inhibitory compounds and a EGFR inhibitor |
US9439899B2 (en) | 2011-11-02 | 2016-09-13 | Synta Pharmaceuticals Corp. | Cancer therapy using a combination of HSP90 inhibitors with topoisomerase I inhibitors |
US10500193B2 (en) | 2011-11-02 | 2019-12-10 | Synta Pharmaceuticals Corporation | Combination therapy of HSP90 inhibitors with platinum-containing agents |
US9402831B2 (en) | 2011-11-14 | 2016-08-02 | Synta Pharmaceutical Corp. | Combination therapy of HSP90 inhibitors with BRAF inhibitors |
Also Published As
Publication number | Publication date |
---|---|
JPS6310924B2 (en) | 1988-03-10 |
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