JPS5759883A - Production of chromone-3-carboxylic acid - Google Patents
Production of chromone-3-carboxylic acidInfo
- Publication number
- JPS5759883A JPS5759883A JP13530180A JP13530180A JPS5759883A JP S5759883 A JPS5759883 A JP S5759883A JP 13530180 A JP13530180 A JP 13530180A JP 13530180 A JP13530180 A JP 13530180A JP S5759883 A JPS5759883 A JP S5759883A
- Authority
- JP
- Japan
- Prior art keywords
- chromone
- carboxylic acid
- compound
- halogenosuccinimide
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- PCIITXGDSHXTSN-UHFFFAOYSA-N Chromone-3-carboxylic acid Chemical compound C1=CC=C2C(=O)C(C(=O)O)=COC2=C1 PCIITXGDSHXTSN-UHFFFAOYSA-N 0.000 title abstract 2
- YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000002351 wastewater Substances 0.000 abstract 2
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000003266 anti-allergic effect Effects 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 239000010802 sludge Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Pyrane Compounds (AREA)
Abstract
PURPOSE: The reaction between a chromone-3-carboxyldehyde and an N-halogenosuccinimide is followed by the hydrolysis of the product to produce the titled compound used as an antiallergic without difficulty in waste water disposition.
CONSTITUTION: The reaction between a compound of formulaI(R is H, monovalent substituent; n is 1, 2) and an N-halogenosuccinimide is effected in a solvent such as dichloromethane under irradiation with light at 40W100°C. Then, the product is hydrolyzed with water to give chromone-3-carboxylic acid of formula II. The compound of formula II also is used as a synthetic intermediate of an antibiotic. The waste water from the process can be satisfactorily disposed by a usual method such as the activated sludge process.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13530180A JPS5759883A (en) | 1980-09-30 | 1980-09-30 | Production of chromone-3-carboxylic acid |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP13530180A JPS5759883A (en) | 1980-09-30 | 1980-09-30 | Production of chromone-3-carboxylic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5759883A true JPS5759883A (en) | 1982-04-10 |
Family
ID=15148500
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP13530180A Pending JPS5759883A (en) | 1980-09-30 | 1980-09-30 | Production of chromone-3-carboxylic acid |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5759883A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4513145A (en) * | 1982-12-28 | 1985-04-23 | Eisai Co., Ltd. | 2-Methylchromone derivatives and process for their preparation |
| US4628107A (en) * | 1983-03-25 | 1986-12-09 | Bayer Aktiengesellschaft | Intermediate 8-carboxaldehyde-(-chromone and -thiochromone) derivatives |
-
1980
- 1980-09-30 JP JP13530180A patent/JPS5759883A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4513145A (en) * | 1982-12-28 | 1985-04-23 | Eisai Co., Ltd. | 2-Methylchromone derivatives and process for their preparation |
| US4628107A (en) * | 1983-03-25 | 1986-12-09 | Bayer Aktiengesellschaft | Intermediate 8-carboxaldehyde-(-chromone and -thiochromone) derivatives |
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