[go: up one dir, main page]

JPS5742616A - Ubiquinone pharmaceutical having improved absorption - Google Patents

Ubiquinone pharmaceutical having improved absorption

Info

Publication number
JPS5742616A
JPS5742616A JP11813580A JP11813580A JPS5742616A JP S5742616 A JPS5742616 A JP S5742616A JP 11813580 A JP11813580 A JP 11813580A JP 11813580 A JP11813580 A JP 11813580A JP S5742616 A JPS5742616 A JP S5742616A
Authority
JP
Japan
Prior art keywords
ubiquinone
oil
capsules
pharmaceutical
absorption
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP11813580A
Other languages
Japanese (ja)
Inventor
Shimesu Motoyama
Satoru Sato
Seiichi Umeda
Hirotsune Yasumi
Emiko Sudo
Takuichi Tsujino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
FUROINTO SANGYO KK
Freund Corp
Original Assignee
FUROINTO SANGYO KK
Freund Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by FUROINTO SANGYO KK, Freund Corp filed Critical FUROINTO SANGYO KK
Priority to JP11813580A priority Critical patent/JPS5742616A/en
Publication of JPS5742616A publication Critical patent/JPS5742616A/en
Pending legal-status Critical Current

Links

Landscapes

  • Medicinal Preparation (AREA)

Abstract

PURPOSE: A ubiquinone pharmaceutical, useful for improving angina pectoris, e.g. ischemic heart disease, having improved absorption in the body by the oral administration, prepared by dispersing the ubiquinone in an oil, and filling the resultant dispersion into capsules of particle diameter ≤3mm, and having the vitamin E action.
CONSTITUTION: A ubiquinone expressed by the formula (n is an integer 1W10) is dispersed in an oil, preferably an essential oil, e.g. peppermit oil or spearmint oil, containing carvone, particularly the carvone, in the form of molecules and/or fine particles, and the resultant dispersion is then filled into capsules having a particle diameter ≤3mm. Alternatively, the ubiquinone is dispersed in the oil and filled into capsules. The resultant capsules and an enzymic group containing a digestive enzyme, preferably pancreatin, are incorporated into the respective pharmaceutical units. Thus, a ubiquinone pharmaceutical having good absorption particularly in digestive tracts, a large area (AUC) under the curve of concentration in blood after the oral administration, and high bioavailability and good lymphatic absorption is obtained.
COPYRIGHT: (C)1982,JPO&Japio
JP11813580A 1980-08-27 1980-08-27 Ubiquinone pharmaceutical having improved absorption Pending JPS5742616A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11813580A JPS5742616A (en) 1980-08-27 1980-08-27 Ubiquinone pharmaceutical having improved absorption

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11813580A JPS5742616A (en) 1980-08-27 1980-08-27 Ubiquinone pharmaceutical having improved absorption

Publications (1)

Publication Number Publication Date
JPS5742616A true JPS5742616A (en) 1982-03-10

Family

ID=14728909

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11813580A Pending JPS5742616A (en) 1980-08-27 1980-08-27 Ubiquinone pharmaceutical having improved absorption

Country Status (1)

Country Link
JP (1) JPS5742616A (en)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6133118A (en) * 1984-04-09 1986-02-17 ゾイレフ・アクチエンゲゼルシヤフト Metabolism activator for anti-cerebral anoxia
JPS62201823A (en) * 1986-02-28 1987-09-05 Freunt Ind Co Ltd Material containing beneficial enterobacterium and production thereof
US5298246A (en) * 1991-01-09 1994-03-29 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Stable pharmaceutical composition and method for its production
WO2005032278A1 (en) * 2003-09-29 2005-04-14 Soft Gel Technologies, Inc. SOLUBILIZED CoQ-10
JP2005112753A (en) * 2003-10-06 2005-04-28 Sankyo:Kk Soft capsule having improved bioavailability
WO2005092123A1 (en) * 2004-03-03 2005-10-06 Soft Gel Technologies, Inc. Solubilized coq-10 and carnitine
JP2007507427A (en) * 2003-09-29 2007-03-29 ソフト ジェル テクノロジーズ， インコーポレイテッド Solubilized CoQ-10
JP2007297395A (en) * 2006-05-05 2007-11-15 Softgel Formulators Inc Highly absorbable coenzyme q10 composition and method for producing the same
US8158162B2 (en) 2001-11-14 2012-04-17 Jarrow Formulas, Inc. Eutectic-based self-nanoemulsified drug delivery system
US20140328928A1 (en) * 2002-01-03 2014-11-06 Christopher J. Milley Stable Aqueous Suspension

Cited By (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4684520A (en) * 1984-04-09 1987-08-04 Seuref A.G. Pharmaceutical compositions having cerebral antianoxic and metabolic activities
JPH0530813B2 (en) * 1984-04-09 1993-05-11 Zoirefu Ag
JPS6133118A (en) * 1984-04-09 1986-02-17 ゾイレフ・アクチエンゲゼルシヤフト Metabolism activator for anti-cerebral anoxia
JPS62201823A (en) * 1986-02-28 1987-09-05 Freunt Ind Co Ltd Material containing beneficial enterobacterium and production thereof
US5298246A (en) * 1991-01-09 1994-03-29 Kanegafuchi Kagaku Kogyo Kabushiki Kaisha Stable pharmaceutical composition and method for its production
US8158162B2 (en) 2001-11-14 2012-04-17 Jarrow Formulas, Inc. Eutectic-based self-nanoemulsified drug delivery system
US8790723B2 (en) 2001-11-14 2014-07-29 Jarrow Formulas, Inc. Eutectic-based self-nanoemulsified drug delivery system
US9775910B2 (en) * 2002-01-03 2017-10-03 Ingredient Innovations International Stable aqueous suspension
US20140328928A1 (en) * 2002-01-03 2014-11-06 Christopher J. Milley Stable Aqueous Suspension
WO2005032278A1 (en) * 2003-09-29 2005-04-14 Soft Gel Technologies, Inc. SOLUBILIZED CoQ-10
US10166193B2 (en) * 2003-09-29 2019-01-01 Soft Gel Technologies, Inc. Method of making a soft gel capsule comprising CoQ-10 solubilized in a monoterpene
US10314793B2 (en) 2003-09-29 2019-06-11 Soft Gel Technologies, Inc. Solubilized CoQ-10
US7713523B2 (en) 2003-09-29 2010-05-11 Soft Gel Technologies, Inc. Solubilized CoQ-10 and carnitine
JP4758898B2 (en) * 2003-09-29 2011-08-31 ソフト ジェル テクノロジーズ， インコーポレイテッド Solubilized CoQ-10
JP2007507427A (en) * 2003-09-29 2007-03-29 ソフト ジェル テクノロジーズ， インコーポレイテッド Solubilized CoQ-10
US7169385B2 (en) 2003-09-29 2007-01-30 Ronald G. Udell Solubilized CoQ-10 and carnitine
US20190091157A1 (en) * 2003-09-29 2019-03-28 Soft Gel Technologies, Inc. Method of Making a Soft Gel Capsule Comprising COQ-10 Solubilized in a Monoterpene
US20150004304A1 (en) * 2003-09-29 2015-01-01 Soft Gel Technologies, Inc. SOLUBILIZED CoQ-10
US10166192B2 (en) 2003-09-29 2019-01-01 Soft Gel Technologies, Inc. Solubilized CoQ-10
US7273606B2 (en) 2003-09-29 2007-09-25 Soft Gel Technologies, Inc. Solubilized CoQ-10 and carnitine
JP2005112753A (en) * 2003-10-06 2005-04-28 Sankyo:Kk Soft capsule having improved bioavailability
WO2005092123A1 (en) * 2004-03-03 2005-10-06 Soft Gel Technologies, Inc. Solubilized coq-10 and carnitine
JP2007297395A (en) * 2006-05-05 2007-11-15 Softgel Formulators Inc Highly absorbable coenzyme q10 composition and method for producing the same

Similar Documents

Publication Publication Date Title
US5004611A (en) Pro-liposome compositions
DE60027717T2 (en) ORAL COMPOSITION FOR MUSHROOM TREATMENT CONTAINING ITRACONAZOLE AND MANUFACTURING METHOD THEREOF
CN1091368C (en) Pharmaceutical composition comprising coenzyme Q10
EP0267702B1 (en) Spray dried acetaminophen
ATE55243T1 (en) LIPIDNANOPELLETS AS A CARRIER SYSTEM FOR DRUGS FOR PORAL APPLICATION.
ES2053549T3 (en) A PROCESS FOR THE PREPARATION OF AN APPROPRIATE PHARMACEUTICAL FORMULATION FOR INHALATION.
HUP0004050A2 (en) Itraconazole exhibiting improved solubility, a method of preparing the same and pharmaceutical composition for oral administration comprising the same
JPS5742616A (en) Ubiquinone pharmaceutical having improved absorption
JPS57212114A (en) Capsule containing allergen activator and preparation therefor
DE69804624D1 (en) SELF-TEMPERATURE FORMULATION CONTAINING LIPOPHILE COMPOUNDS
KR860000068A (en) Method of Providing Sustainability to Drugs
MY124599A (en) Oral suspension of pharmaceutical substance
EP0209037B1 (en) Pharmaceutical compositions containing flavanolignanes and phospholipids as active principles
RU94035739A (en) Pharmaceutical composition containing nifedipin and method of its preparing
KR890000084A (en) Solid Drugs Containing Epselene Microcrystals
EP0152292A2 (en) Acetaminophen gelatin capsules
EP0542930B1 (en) Oral pharmaceutical compositions containing melatonin
CA2078869A1 (en) Pharmaceutical compositions containing ipriflavone, process for the preparation thereof and relative therapeutic use
UA74793C2 (en) Bioavailable pharmaceutical composition of isotretinoin and process for preparing such composition
ITMI970047A1 (en) ANTI-TUBERCULAR PHARMACEUTICAL COMPOSITION AND PROCEDURE FOR ITS PRODUCTION
Sofia et al. Evaluation of antiulcer activity of Δ9-tetrahydrocannabinol in the Shay rat test
Ozawa et al. Intestinal absorption enhancement of coenzyme Q10 with a lipid microsphere
JPS5522631A (en) Readily absorbable nifedipine preparation
JPS56161317A (en) Pharmaceutical preparation of fatty corpuscle of steroid
US20060233842A1 (en) Microemulsion composition for oral administration of biphenyldimethyldicarboxylate