JPS57206397A - Preparation of antibiotic substance at-265 and/or at-265-b - Google Patents
Preparation of antibiotic substance at-265 and/or at-265-bInfo
- Publication number
- JPS57206397A JPS57206397A JP5387981A JP5387981A JPS57206397A JP S57206397 A JPS57206397 A JP S57206397A JP 5387981 A JP5387981 A JP 5387981A JP 5387981 A JP5387981 A JP 5387981A JP S57206397 A JPS57206397 A JP S57206397A
- Authority
- JP
- Japan
- Prior art keywords
- cultivating
- antibiotic substance
- microorganism
- gram
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000003115 biocidal effect Effects 0.000 title abstract 2
- 239000000126 substance Substances 0.000 title abstract 2
- 244000005700 microbiome Species 0.000 abstract 2
- NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 abstract 1
- 241000186046 Actinomyces Species 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 abstract 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 229920002472 Starch Polymers 0.000 abstract 1
- 241000187747 Streptomyces Species 0.000 abstract 1
- 241000970863 Streptomyces rishiriensis Species 0.000 abstract 1
- 240000008042 Zea mays Species 0.000 abstract 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 abstract 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 235000005822 corn Nutrition 0.000 abstract 1
- 238000003795 desorption Methods 0.000 abstract 1
- 239000000706 filtrate Substances 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 239000008103 glucose Substances 0.000 abstract 1
- 235000001727 glucose Nutrition 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
- 239000003456 ion exchange resin Substances 0.000 abstract 1
- 229920003303 ion-exchange polymer Polymers 0.000 abstract 1
- 235000013372 meat Nutrition 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- 238000010898 silica gel chromatography Methods 0.000 abstract 1
- 238000001179 sorption measurement Methods 0.000 abstract 1
- 239000008107 starch Substances 0.000 abstract 1
- 235000019698 starch Nutrition 0.000 abstract 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Abstract
PURPOSE: To accumulate and collect the titled antibiotics having the antimicrobial activity against Gram-positive and Gram-negative bacteria, by cultivating a microorganism belonging to the genus Streptomyces.
CONSTITUTION: A microorganism, e.g. Streptomyces rishiriensis subspecies SP- 265, is cultivated in a usual culture medium for cultivating actinomyces, e.g. containing glucose, starch, meat extract, corn steep liquor, phosphate or carbonate. Microbial cells are removed from the culture by the filtration, etc. and the aimed novel antibiotic substance AT-265 or AT-265-B or both are obtained from the filtrate by the adsorption and desorption method with an ion exchange resin, silica gel chromatography, etc.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5387981A JPS57206397A (en) | 1981-04-10 | 1981-04-10 | Preparation of antibiotic substance at-265 and/or at-265-b |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5387981A JPS57206397A (en) | 1981-04-10 | 1981-04-10 | Preparation of antibiotic substance at-265 and/or at-265-b |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS57206397A true JPS57206397A (en) | 1982-12-17 |
| JPH0123117B2 JPH0123117B2 (en) | 1989-05-01 |
Family
ID=12955028
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP5387981A Granted JPS57206397A (en) | 1981-04-10 | 1981-04-10 | Preparation of antibiotic substance at-265 and/or at-265-b |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS57206397A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5824657A (en) * | 1997-03-18 | 1998-10-20 | Cubist Pharmaceuticals, Inc. | Aminoacyl sulfamides for the treatment of hyperproliferative disorders |
-
1981
- 1981-04-10 JP JP5387981A patent/JPS57206397A/en active Granted
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5824657A (en) * | 1997-03-18 | 1998-10-20 | Cubist Pharmaceuticals, Inc. | Aminoacyl sulfamides for the treatment of hyperproliferative disorders |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0123117B2 (en) | 1989-05-01 |
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