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JPS57194798A - Production of polysaccharide - Google Patents

Production of polysaccharide

Info

Publication number
JPS57194798A
JPS57194798A JP56078620A JP7862081A JPS57194798A JP S57194798 A JPS57194798 A JP S57194798A JP 56078620 A JP56078620 A JP 56078620A JP 7862081 A JP7862081 A JP 7862081A JP S57194798 A JPS57194798 A JP S57194798A
Authority
JP
Japan
Prior art keywords
polysaccharide
molecular weight
medium
increase
serum cholesterol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP56078620A
Other languages
Japanese (ja)
Other versions
JPH0223159B2 (en
Inventor
Minoru Tanaka
Yoshiaki Machida
Shozo Tanaka
Hiroshi Okamatsu
Tsuneya Yamu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Showa Sangyo Co Ltd
Original Assignee
Showa Sangyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Showa Sangyo Co Ltd filed Critical Showa Sangyo Co Ltd
Priority to JP56078620A priority Critical patent/JPS57194798A/en
Priority to FR8110636A priority patent/FR2487376B1/en
Priority to GB8116459A priority patent/GB2080818B/en
Priority to IT22039/81A priority patent/IT1195275B/en
Priority to NL8102628A priority patent/NL8102628A/en
Priority to DE19813121548 priority patent/DE3121548A1/en
Priority to CH3523/81A priority patent/CH659085A5/en
Publication of JPS57194798A publication Critical patent/JPS57194798A/en
Publication of JPH0223159B2 publication Critical patent/JPH0223159B2/ja
Granted legal-status Critical Current

Links

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  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

PURPOSE: Bacillus polymyxa 271 is cultured in a medium and saccharide of a specific molecular weight is coolected whereby a polysaccharide is obtained, which has a strong activity of reducing atherogenic index and inhibiting the increase in serum cholesterol.
CONSTITUTION: Bacillus polymyxa 271 is inoculated in a medium that is prepared by adding pepton, corn-steep liquor, yeast extract, urea or other nitrogen sources and salts such as magnesium sulfate to a solution containing about 3W 5% of glucose, sucrose, lactose or molasses as a carbon source and cultured aerobically. The resultant high-viscosity polysaccharide is precipitated with methanol, subjected to ultrafiltration to effect the purification and give the objective polysaccharide of more than 200,000mol.wt. The molecular weight of the above polysaccharide is required to be more than 200,000 so that the polysaccharide may have activities of strongly inhibiting the increase in the serum cholesterol and remarkably reducing the atherogenic index.
COPYRIGHT: (C)1982,JPO&Japio
JP56078620A 1980-07-28 1981-05-26 Production of polysaccharide Granted JPS57194798A (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP56078620A JPS57194798A (en) 1981-05-26 1981-05-26 Production of polysaccharide
FR8110636A FR2487376B1 (en) 1980-07-28 1981-05-27 PROCESS FOR THE PRODUCTION OF POLYSACCHARIDES BY CULTURE OF A BACILLUS
GB8116459A GB2080818B (en) 1980-07-28 1981-05-29 A microbiological process for the production of a polysaccharide and its cationic salt and their use in depressing serum and liver cholesterol levels and the atherogenic index
IT22039/81A IT1195275B (en) 1980-07-28 1981-05-29 PROCEDURE FOR THE PRODUCTION OF A POLYSACCHARIDE
NL8102628A NL8102628A (en) 1980-07-28 1981-05-29 PROCESS FOR PREPARING A POLYSACCHARIDE FROM BACTERIA.
DE19813121548 DE3121548A1 (en) 1980-07-28 1981-05-29 Process for the preparation of a polysaccharide
CH3523/81A CH659085A5 (en) 1980-07-28 1981-06-25 PROCESS FOR THE SYNTHESIS OF A POLYSACCHARIDE.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56078620A JPS57194798A (en) 1981-05-26 1981-05-26 Production of polysaccharide

Publications (2)

Publication Number Publication Date
JPS57194798A true JPS57194798A (en) 1982-11-30
JPH0223159B2 JPH0223159B2 (en) 1990-05-23

Family

ID=13666926

Family Applications (1)

Application Number Title Priority Date Filing Date
JP56078620A Granted JPS57194798A (en) 1980-07-28 1981-05-26 Production of polysaccharide

Country Status (1)

Country Link
JP (1) JPS57194798A (en)

Also Published As

Publication number Publication date
JPH0223159B2 (en) 1990-05-23

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