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JPS57145811A - Carcinostatic agent containing lysophospholipid and phospholipid and preparation thereof - Google Patents

Carcinostatic agent containing lysophospholipid and phospholipid and preparation thereof

Info

Publication number
JPS57145811A
JPS57145811A JP1340082A JP1340082A JPS57145811A JP S57145811 A JPS57145811 A JP S57145811A JP 1340082 A JP1340082 A JP 1340082A JP 1340082 A JP1340082 A JP 1340082A JP S57145811 A JPS57145811 A JP S57145811A
Authority
JP
Japan
Prior art keywords
lysophospholipid
carcinostatic agent
phospholipid
carcinostatic
agent containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1340082A
Other languages
Japanese (ja)
Other versions
JPS6350330B2 (en
Inventor
Hiroshi Kodama
Kaoru Ooyama
Ryusaku Shimizu
Masao Nakabayashi
Yoshifumi Nakajima
Takashi Sano
Masaaki Shibata
Kiyoshi Goda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyama Chemical Co Ltd
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Priority to JP1340082A priority Critical patent/JPS57145811A/en
Publication of JPS57145811A publication Critical patent/JPS57145811A/en
Publication of JPS6350330B2 publication Critical patent/JPS6350330B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE: To obtain a highly safe carcinostatic agent capable of reducing the hemolytic action without affecting carcinostatic action a specific lysophospholipid and angiopathy even in the continued parenteral use, by incorporating the lysophospholipid with a phospholipid.
CONSTITUTION: A carcinostatic agent containing (A) a compound expressed by the formula (R1 is 5W22C acyloxy or 5W22C alkoxyl; R2 is H, OH, 1W5C alkoxyl, 1W5C acyloxy or R1 and R2 are mutually exchangeable, except compounds in which R1 and R2 are mutually exchangeable, except compounds in which R1 is 14W1C alkanolyloxy; R2 is HO; R3 is CH3) or a lysophospholipid consisting essentially thereof and (B) preferably a naturally occurring phospholipid at a weight ratio between the components (A) and (B) of 1: (1.0W500), preferably in the dosage form of a dispersion of dispersed lipid cytoplasmic reticula having a particle diameter ≤0.5μ. The carcinostatic agent may contain further (C) a fat or oil or (D) a fatty emulsion.
COPYRIGHT: (C)1982,JPO&Japio
JP1340082A 1982-02-01 1982-02-01 Carcinostatic agent containing lysophospholipid and phospholipid and preparation thereof Granted JPS57145811A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1340082A JPS57145811A (en) 1982-02-01 1982-02-01 Carcinostatic agent containing lysophospholipid and phospholipid and preparation thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1340082A JPS57145811A (en) 1982-02-01 1982-02-01 Carcinostatic agent containing lysophospholipid and phospholipid and preparation thereof

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP11726279A Division JPS5840929B2 (en) 1979-03-05 1979-09-14 Anticancer agent containing lysolecithin and phospholipid and its manufacturing method

Publications (2)

Publication Number Publication Date
JPS57145811A true JPS57145811A (en) 1982-09-09
JPS6350330B2 JPS6350330B2 (en) 1988-10-07

Family

ID=11832066

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1340082A Granted JPS57145811A (en) 1982-02-01 1982-02-01 Carcinostatic agent containing lysophospholipid and phospholipid and preparation thereof

Country Status (1)

Country Link
JP (1) JPS57145811A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01203330A (en) * 1988-02-05 1989-08-16 Rikagaku Kenkyusho anticancer drug
JP2007176868A (en) * 2005-12-28 2007-07-12 Nagase Chemtex Corp beta-GLUCURONIDASE INHIBITOR
WO2015152412A1 (en) * 2014-04-04 2015-10-08 国立大学法人大阪大学 Drug delivery promoter containing substance for activating lysophospholipid receptors

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6396834U (en) * 1986-12-16 1988-06-22

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01203330A (en) * 1988-02-05 1989-08-16 Rikagaku Kenkyusho anticancer drug
JP2007176868A (en) * 2005-12-28 2007-07-12 Nagase Chemtex Corp beta-GLUCURONIDASE INHIBITOR
WO2015152412A1 (en) * 2014-04-04 2015-10-08 国立大学法人大阪大学 Drug delivery promoter containing substance for activating lysophospholipid receptors
JPWO2015152412A1 (en) * 2014-04-04 2017-04-13 国立大学法人大阪大学 Drug delivery accelerator containing substance that activates lysophospholipid receptor

Also Published As

Publication number Publication date
JPS6350330B2 (en) 1988-10-07

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