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JPS5679699A - Production of 6-thioguanine nucleoside - Google Patents

Production of 6-thioguanine nucleoside

Info

Publication number
JPS5679699A
JPS5679699A JP15562379A JP15562379A JPS5679699A JP S5679699 A JPS5679699 A JP S5679699A JP 15562379 A JP15562379 A JP 15562379A JP 15562379 A JP15562379 A JP 15562379A JP S5679699 A JPS5679699 A JP S5679699A
Authority
JP
Japan
Prior art keywords
protecting group
sulfide
hydroxyl bearing
nucleoside
bearing protecting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP15562379A
Other languages
Japanese (ja)
Other versions
JPS5710120B2 (en
Inventor
Shinji Sakata
Toru Ueda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamasa Shoyu KK
Original Assignee
Yamasa Shoyu KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamasa Shoyu KK filed Critical Yamasa Shoyu KK
Priority to JP15562379A priority Critical patent/JPS5679699A/en
Publication of JPS5679699A publication Critical patent/JPS5679699A/en
Publication of JPS5710120B2 publication Critical patent/JPS5710120B2/ja
Granted legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PURPOSE: The reaction of an arenesulfonylguanine nucleoside with a sulfide such as hydrogen sulfide gives the titled compound used as an antitumorigenic agent with industrial advantage.
CONSTITUTION: A 6-alkylsulfonyl or arenesulfonylguanine nucleoside of formula I [R1 is H, protecting group; R'2WR'5 are H, hydroxyl bearing protecting groups (where the cases are excluded where both combinations of R'2, R'3 and R'4, R'5 are hydroxyls bearing protecting groups); R'6 is hydroxyl bearing a protecting group; R7 is alkylsulfonyl, alkylenesulfonyl] is made to react with a sulfide such as hydrogen sulfide, sodium hydrosulfide or alkali metal sulfide to produce the objective compound of formula II [R2WR5 are H, hydroxyl bearing protecting group (where, when one combination of R2, R3 and R4, R5 is hydroxyl bearing protecting group, the other is H); R6 is hydroxyl bearing protecting group].
COPYRIGHT: (C)1981,JPO&Japio
JP15562379A 1979-12-03 1979-12-03 Production of 6-thioguanine nucleoside Granted JPS5679699A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP15562379A JPS5679699A (en) 1979-12-03 1979-12-03 Production of 6-thioguanine nucleoside

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15562379A JPS5679699A (en) 1979-12-03 1979-12-03 Production of 6-thioguanine nucleoside

Publications (2)

Publication Number Publication Date
JPS5679699A true JPS5679699A (en) 1981-06-30
JPS5710120B2 JPS5710120B2 (en) 1982-02-24

Family

ID=15610042

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15562379A Granted JPS5679699A (en) 1979-12-03 1979-12-03 Production of 6-thioguanine nucleoside

Country Status (1)

Country Link
JP (1) JPS5679699A (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59221021A (en) * 1983-05-30 1984-12-12 Matsushita Electric Ind Co Ltd Resonator
JPS6050528U (en) * 1983-09-12 1985-04-09 松下電器産業株式会社 piezoelectric ceramic filter
JPH0327121U (en) * 1989-07-24 1991-03-19

Also Published As

Publication number Publication date
JPS5710120B2 (en) 1982-02-24

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