[go: up one dir, main page]

JPS5675437A - Suppository base - Google Patents

Suppository base

Info

Publication number
JPS5675437A
JPS5675437A JP15124379A JP15124379A JPS5675437A JP S5675437 A JPS5675437 A JP S5675437A JP 15124379 A JP15124379 A JP 15124379A JP 15124379 A JP15124379 A JP 15124379A JP S5675437 A JPS5675437 A JP S5675437A
Authority
JP
Japan
Prior art keywords
oil
suppository
suppository base
fatty acid
soluble substance
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP15124379A
Other languages
Japanese (ja)
Other versions
JPS6220963B2 (en
Inventor
Hiroshi Sugiyama
Fusayuki Saito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Adeka Corp
Original Assignee
Asahi Denka Kogyo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Denka Kogyo KK filed Critical Asahi Denka Kogyo KK
Priority to JP15124379A priority Critical patent/JPS5675437A/en
Publication of JPS5675437A publication Critical patent/JPS5675437A/en
Publication of JPS6220963B2 publication Critical patent/JPS6220963B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Medicinal Preparation (AREA)

Abstract

PURPOSE: A suppository base having increased release rate of a drug and improved adhesion or cracking in preparation, and containing a specific sucrose ester of a fatty acid and an oil-soluble substance.
CONSTITUTION: A suppository base consisting of 2W15pts.wt. sucrose ester of a fatty acid having an HLB of 1W5 (hydrophilic-lipophilic balance) consisting of 0W 30wt% a monoester and 70W100wt% a polyester of di- or polyester and 85W 98pts.wt. an oil-soluble substance. The oil-soluble substance consists of a triglyceride of 12W18C vegetable saturated fatty acid, e.g. cacao substitute fat, essentially. The resultant suppository base has improved releasability of the drug without degrading the rapid melting property of a fat or oil when inserted into a body cavity and will not cause adhesion to a suppository mold, cracking or forming a cativy in molding of the suppository.
COPYRIGHT: (C)1981,JPO&Japio
JP15124379A 1979-11-21 1979-11-21 Suppository base Granted JPS5675437A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP15124379A JPS5675437A (en) 1979-11-21 1979-11-21 Suppository base

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15124379A JPS5675437A (en) 1979-11-21 1979-11-21 Suppository base

Publications (2)

Publication Number Publication Date
JPS5675437A true JPS5675437A (en) 1981-06-22
JPS6220963B2 JPS6220963B2 (en) 1987-05-11

Family

ID=15514382

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15124379A Granted JPS5675437A (en) 1979-11-21 1979-11-21 Suppository base

Country Status (1)

Country Link
JP (1) JPS5675437A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62158207A (en) * 1986-01-06 1987-07-14 Showa Yakuhin Kako Kk Composition for rectal administration
US7666860B2 (en) * 2003-09-04 2010-02-23 Gruenenthal Gmbh Melt-formulated, multi-particulate oral dosage form

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10190598B2 (en) 2016-02-18 2019-01-29 Pratt & Whitney Canada Corp. Intermittent spigot joint for gas turbine engine casing connection

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5244222A (en) * 1975-09-30 1977-04-07 Yamanouchi Pharmaceut Co Ltd Method of making insulin preparations for rectal application
JPS5264418A (en) * 1975-11-20 1977-05-27 Toyama Chem Co Ltd Method for increasing absorption of novel penicillin in rectal adminis tration
JPS52105220A (en) * 1976-02-28 1977-09-03 Toyama Chem Co Ltd Composition for rectal administration comprising beta-lactam ring containing substance and method of making same
JPS52107408A (en) * 1976-03-05 1977-09-09 Hitachi Ltd Grooved fringe

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5244222A (en) * 1975-09-30 1977-04-07 Yamanouchi Pharmaceut Co Ltd Method of making insulin preparations for rectal application
JPS5264418A (en) * 1975-11-20 1977-05-27 Toyama Chem Co Ltd Method for increasing absorption of novel penicillin in rectal adminis tration
JPS52105220A (en) * 1976-02-28 1977-09-03 Toyama Chem Co Ltd Composition for rectal administration comprising beta-lactam ring containing substance and method of making same
JPS52107408A (en) * 1976-03-05 1977-09-09 Hitachi Ltd Grooved fringe

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62158207A (en) * 1986-01-06 1987-07-14 Showa Yakuhin Kako Kk Composition for rectal administration
JPH0521895B2 (en) * 1986-01-06 1993-03-25 Showa Pharm Chem Ind
US7666860B2 (en) * 2003-09-04 2010-02-23 Gruenenthal Gmbh Melt-formulated, multi-particulate oral dosage form

Also Published As

Publication number Publication date
JPS6220963B2 (en) 1987-05-11

Similar Documents

Publication Publication Date Title
DE2967049D1 (en) Pharmaceutical and dietary composition comprising gamma-linolenic acids
DE2961102D1 (en) Pharmaceutical and dietary composition comprising gamma-linolenic acids
IL54149A (en) Fluoro-3-phenoxybenzyl alcohol and its esters with 2,2-dimethyl-3-(2,2-disubstituted vinyl)cyclopropane carboxylic and alpha-isopropylphenylacetic acids,their preparation and the use of the esters as insecticides and acaricides
JPS5618914A (en) Ubidecarenone composition having good absorbability
IL60127A (en) 3-phenoxybenzyl esters of 2-phenyl-alk-1-enyl-cyclopropane-carboxylic acid,their preparation and their use as insecticides and acaricides
JPS5558060A (en) Preparation of hard butter
IL57831A (en) Stilbene methanol esters of pyrethrinoid acids,their preparation and insecticidal and acaricidal compositions containing them
NZ190842A (en) 4-substituted-thiazole-2-oxamic acids and esters and pharmaceutical compositions
DE3060142D1 (en) Unsaturated fatty alcohols and process for their preparation
ZA884622B (en) Pharmaceutical compositions in the form of pellets with enzymatically controlled release of the pharmaceutical,substance
JPS5675437A (en) Suppository base
JPS57183772A (en) Aminocyclopentanol acids and esters, manufacture and medicinal composition
JPS5432561A (en) Polyester resin composition
IL56822A (en) Pentafluorobenzyl esters of substituted cyclopropanecarboxilic acids,their preparation and their use as insecticides and acaricides
IL51466A (en) 2-methyl-3-(2-phenylvinyl)-cyclo-propanecarboxylic acid esters with 3-phenoxybenzyl alcohol derivatives, their prepation and acaricidal and insecticidal compositions containing them
ZA792043B (en) Esters of substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepines,process for the preparation thereof and pharmaceutical compositions containing them
GB2057427B (en) Oxoimidazolinealkanoic acids and their salts and esters their preparation and pharmaceutical compositions containing them
JPS5626152A (en) Production of chocolatelike confection
JPS5549313A (en) Vitamin pharmaceutical and its preparation
DE3061357D1 (en) Preparation of esters containing an alpha cyano group in the alcohol portion of the ester
JPS52100506A (en) Creamy composition and fatty composition suitable for producing same
AU6724890A (en) Method for the preparation of fat mixtures comprising eicosapentaenoate ester from worms of family lumbricidae and, optionally fatty acid mixtures comprising eicosapentaenoic acid therefrom
IL60064A (en) Alkoxyfluoroalkenyldimethylcyclopropanecarboxylic acids and their esters,their preparation and use of certain esters as insecticides and acaricides
DE2962203D1 (en) Polyunsaturated aliphatic esters, process for their preparation and their use as flavouring and odoriferous ingredients
IL56031A (en) 2(or 4)-chloro-2-(2,2-dichlorovinyl)cyclobutanones,their preparation,and use as intermediates in the preparation of 2-(2,2-dichlorovinyl)cyclopropanecarboxylic acids and esters