JPS5624664B2 - - Google Patents
Info
- Publication number
- JPS5624664B2 JPS5624664B2 JP7340573A JP7340573A JPS5624664B2 JP S5624664 B2 JPS5624664 B2 JP S5624664B2 JP 7340573 A JP7340573 A JP 7340573A JP 7340573 A JP7340573 A JP 7340573A JP S5624664 B2 JPS5624664 B2 JP S5624664B2
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
- C08K5/00—Use of organic ingredients
- C08K5/16—Nitrogen-containing compounds
- C08K5/20—Carboxylic acid amides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Polyethers (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Paper (AREA)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7340573A JPS5624664B2 (fr) | 1973-06-28 | 1973-06-28 | |
IT2444874A IT1015418B (it) | 1973-06-28 | 1974-06-25 | Composti organici e procedimento per la loro preparazione |
DE19742430998 DE2430998A1 (de) | 1973-06-28 | 1974-06-27 | Neue organische verbindungen mit einer n,n-dialkylsubstibuierten amidgruppe und verfahren zu deren herstellung |
FR7422691A FR2235112A1 (en) | 1973-06-28 | 1974-06-28 | Cpds contg dialkyl-substd amide gps - used as surfactants, dispersants, solvents, chelating agents and polymer modifiers |
NL7408784A NL7408784A (fr) | 1973-06-28 | 1974-06-28 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7340573A JPS5624664B2 (fr) | 1973-06-28 | 1973-06-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5024216A JPS5024216A (fr) | 1975-03-15 |
JPS5624664B2 true JPS5624664B2 (fr) | 1981-06-08 |
Family
ID=13517239
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP7340573A Expired JPS5624664B2 (fr) | 1973-06-28 | 1973-06-28 |
Country Status (5)
Country | Link |
---|---|
JP (1) | JPS5624664B2 (fr) |
DE (1) | DE2430998A1 (fr) |
FR (1) | FR2235112A1 (fr) |
IT (1) | IT1015418B (fr) |
NL (1) | NL7408784A (fr) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5524563A (en) * | 1978-08-09 | 1980-02-21 | Nitto Electric Ind Co Ltd | Tubular membrane separating module |
AU2006259415B2 (en) * | 2005-06-15 | 2012-08-30 | Massachusetts Institute Of Technology | Amine-containing lipids and uses thereof |
JP6087504B2 (ja) | 2008-11-07 | 2017-03-01 | マサチューセッツ インスティテュート オブ テクノロジー | アミノアルコールリピドイドおよびその使用 |
EP2506857B1 (fr) | 2009-12-01 | 2018-02-14 | Translate Bio, Inc. | Administration d'arnm pour l'augmentation des protéines et des enzymes dans des maladies génétiques humaines |
CA2831392C (fr) | 2011-03-28 | 2020-04-28 | Massachusetts Institute Of Technology | Lipomeres conjugues et utilisations associees |
TR201910686T4 (tr) | 2011-06-08 | 2019-08-21 | Translate Bio Inc | Mrna iletimine yönelik lipit nanopartikül bileşimleri ve yöntemler. |
US20150267192A1 (en) | 2012-06-08 | 2015-09-24 | Shire Human Genetic Therapies, Inc. | Nuclease resistant polynucleotides and uses thereof |
CA2884870C (fr) | 2012-08-13 | 2022-03-29 | Massachusetts Institute Of Technology | Lipidoides contenant des amines et leurs utilisations |
ES2708561T3 (es) | 2013-03-14 | 2019-04-10 | Translate Bio Inc | Métodos para la purificación de ARN mensajero |
UA117008C2 (uk) | 2013-03-14 | 2018-06-11 | Шир Хьюман Дженетік Терапіс, Інк. | IN VITRO ТРАНСКРИБОВАНА мРНК ТА КОМПОЗИЦІЯ, ЩО ЇЇ МІСТИТЬ, ДЛЯ ЗАСТОСУВАННЯ В ЛІКУВАННІ МУКОВІСЦИДОЗУ В ССАВЦЯ |
WO2014179562A1 (fr) | 2013-05-01 | 2014-11-06 | Massachusetts Institute Of Technology | Dérivés de 1,3,5-triazinane-2,4,6-trione et leurs utilisations |
AU2014340092B2 (en) | 2013-10-22 | 2019-09-19 | Translate Bio, Inc. | mRNA therapy for Argininosuccinate Synthetase Deficiency |
BR112016009077A2 (pt) | 2013-10-22 | 2017-09-19 | Shire Human Genetic Therapies | Formulações lipídicas para fornecimento de rna mensageiro |
EP3574923A1 (fr) | 2013-10-22 | 2019-12-04 | Translate Bio, Inc. | Thérapie d'arnm pour phénylcétonurie |
JP6571679B2 (ja) | 2014-04-25 | 2019-09-04 | トランスレイト バイオ, インコーポレイテッド | メッセンジャーrnaの精製方法 |
EP3148552B1 (fr) | 2014-05-30 | 2019-07-31 | Translate Bio, Inc. | Lipides biodégradables pour l'administration d'acides nucléiques |
US10138213B2 (en) | 2014-06-24 | 2018-11-27 | Translate Bio, Inc. | Stereochemically enriched compositions for delivery of nucleic acids |
US9840479B2 (en) | 2014-07-02 | 2017-12-12 | Massachusetts Institute Of Technology | Polyamine-fatty acid derived lipidoids and uses thereof |
CA3054062A1 (fr) | 2017-02-27 | 2018-08-30 | Translate Bio, Inc. | Nouvel arnm cftr a codons optimises |
EP3624824B1 (fr) | 2017-05-16 | 2024-07-10 | Translate Bio, Inc. | D'arnm à codons optimisés codant pour la cftr pour l'utilisation dans le traitement de la fibrose kystique |
US11174500B2 (en) | 2018-08-24 | 2021-11-16 | Translate Bio, Inc. | Methods for purification of messenger RNA |
WO2020106946A1 (fr) | 2018-11-21 | 2020-05-28 | Translate Bio, Inc. | Traitement de la fibrose kystique par administration d'arnm nébulisé codant pour la cftr |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2372808A (en) * | 1941-07-30 | 1945-04-03 | Resinous Prod & Chemical Co | Esters of poly-beta-carboxyalkyl ethers of polyhydric alcohols |
-
1973
- 1973-06-28 JP JP7340573A patent/JPS5624664B2/ja not_active Expired
-
1974
- 1974-06-25 IT IT2444874A patent/IT1015418B/it active
- 1974-06-27 DE DE19742430998 patent/DE2430998A1/de active Pending
- 1974-06-28 NL NL7408784A patent/NL7408784A/xx unknown
- 1974-06-28 FR FR7422691A patent/FR2235112A1/fr not_active Withdrawn
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2372808A (en) * | 1941-07-30 | 1945-04-03 | Resinous Prod & Chemical Co | Esters of poly-beta-carboxyalkyl ethers of polyhydric alcohols |
Also Published As
Publication number | Publication date |
---|---|
FR2235112A1 (en) | 1975-01-24 |
DE2430998A1 (de) | 1975-01-09 |
IT1015418B (it) | 1977-05-10 |
JPS5024216A (fr) | 1975-03-15 |
NL7408784A (fr) | 1974-12-31 |