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JPS5624664B2 - - Google Patents

Info

Publication number
JPS5624664B2
JPS5624664B2 JP7340573A JP7340573A JPS5624664B2 JP S5624664 B2 JPS5624664 B2 JP S5624664B2 JP 7340573 A JP7340573 A JP 7340573A JP 7340573 A JP7340573 A JP 7340573A JP S5624664 B2 JPS5624664 B2 JP S5624664B2
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP7340573A
Other languages
Japanese (ja)
Other versions
JPS5024216A (en
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to JP7340573A priority Critical patent/JPS5624664B2/ja
Priority to IT2444874A priority patent/IT1015418B/en
Priority to DE19742430998 priority patent/DE2430998A1/en
Priority to FR7422691A priority patent/FR2235112A1/en
Priority to NL7408784A priority patent/NL7408784A/xx
Publication of JPS5024216A publication Critical patent/JPS5024216A/ja
Publication of JPS5624664B2 publication Critical patent/JPS5624664B2/ja
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00Use of organic ingredients
    • C08K5/16Nitrogen-containing compounds
    • C08K5/20Carboxylic acid amides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polyethers (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Paper (AREA)
JP7340573A 1973-06-28 1973-06-28 Expired JPS5624664B2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP7340573A JPS5624664B2 (en) 1973-06-28 1973-06-28
IT2444874A IT1015418B (en) 1973-06-28 1974-06-25 ORGANIC COMPOUNDS AND PROCEDURE FOR THEIR PREPARATION
DE19742430998 DE2430998A1 (en) 1973-06-28 1974-06-27 NEW ORGANIC COMPOUNDS CONTAINING AN N, N-DIALKYL-SUBSTIBUTED AMIDE GROUP AND METHOD OF PREPARING THEREOF
FR7422691A FR2235112A1 (en) 1973-06-28 1974-06-28 Cpds contg dialkyl-substd amide gps - used as surfactants, dispersants, solvents, chelating agents and polymer modifiers
NL7408784A NL7408784A (en) 1973-06-28 1974-06-28

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7340573A JPS5624664B2 (en) 1973-06-28 1973-06-28

Publications (2)

Publication Number Publication Date
JPS5024216A JPS5024216A (en) 1975-03-15
JPS5624664B2 true JPS5624664B2 (en) 1981-06-08

Family

ID=13517239

Family Applications (1)

Application Number Title Priority Date Filing Date
JP7340573A Expired JPS5624664B2 (en) 1973-06-28 1973-06-28

Country Status (5)

Country Link
JP (1) JPS5624664B2 (en)
DE (1) DE2430998A1 (en)
FR (1) FR2235112A1 (en)
IT (1) IT1015418B (en)
NL (1) NL7408784A (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5524563A (en) * 1978-08-09 1980-02-21 Nitto Electric Ind Co Ltd Tubular membrane separating module
EP1912679A4 (en) * 2005-06-15 2009-07-29 Massachusetts Inst Technology LIPIDS CONTAINING AMINES AND USES
MX353900B (en) 2008-11-07 2018-02-01 Massachusetts Inst Technology Aminoalcohol lipidoids and uses thereof.
ES2666559T3 (en) 2009-12-01 2018-05-07 Translate Bio, Inc. Delivery of mrna for the augmentation of proteins and enzymes in human genetic diseases
DK2691443T3 (en) 2011-03-28 2021-05-03 Massachusetts Inst Technology CONJUGIATED LIPOMERS AND USES OF THESE
BR112013031553A2 (en) 2011-06-08 2020-11-10 Shire Human Genetic Therapies, Inc. compositions, mrna encoding a gland and its use, use of at least one mrna molecule and a vehicle for transfer and use of an mrna encoding for exogenous protein
EP2859102A4 (en) 2012-06-08 2016-05-11 Shire Human Genetic Therapies Nuclease resistant polynucleotides and uses thereof
CA2884870C (en) 2012-08-13 2022-03-29 Massachusetts Institute Of Technology Amine-containing lipidoids and uses thereof
EP4446413A3 (en) 2013-03-14 2024-12-18 Translate Bio, Inc. Methods for purification of messenger rna
WO2014153052A2 (en) 2013-03-14 2014-09-25 Shire Human Genetic Therapies, Inc. Cftr mrna compositions and related methods and uses
WO2014179562A1 (en) 2013-05-01 2014-11-06 Massachusetts Institute Of Technology 1,3,5-triazinane-2,4,6-trione derivatives and uses thereof
AU2014340155B2 (en) 2013-10-22 2018-11-01 Massachusetts Institute Of Technology Lipid formulations for delivery of messenger RNA
ES2707966T3 (en) 2013-10-22 2019-04-08 Translate Bio Inc MRNA therapy for the deficiency in argininosuccinate synthesis
CN105658242A (en) 2013-10-22 2016-06-08 夏尔人类遗传性治疗公司 MRNA therapy for phenylketonuria
CN106164248B (en) 2014-04-25 2019-10-15 川斯勒佰尔公司 Purification of messenger RNA
CN106659731A (en) 2014-05-30 2017-05-10 夏尔人类遗传性治疗公司 Topical compositions and methods for treating wounds
JP6599373B2 (en) 2014-06-24 2019-10-30 シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド Stereochemically enriched compositions for delivery of nucleic acids
US9840479B2 (en) 2014-07-02 2017-12-12 Massachusetts Institute Of Technology Polyamine-fatty acid derived lipidoids and uses thereof
MX2019010155A (en) 2017-02-27 2020-12-10 Translate Bio Inc Novel codon-optimized cftr mrna.
WO2018213476A1 (en) 2017-05-16 2018-11-22 Translate Bio, Inc. Treatment of cystic fibrosis by delivery of codon-optimized mrna encoding cftr
KR20210060480A (en) 2018-08-24 2021-05-26 트랜슬레이트 바이오 인코포레이티드 Method for purifying messenger RNA
CA3120647A1 (en) 2018-11-21 2020-05-28 Translate Bio, Inc. Treatment of cystic fibrosis by delivery of nebulized mrna encoding cftr

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2372808A (en) * 1941-07-30 1945-04-03 Resinous Prod & Chemical Co Esters of poly-beta-carboxyalkyl ethers of polyhydric alcohols

Also Published As

Publication number Publication date
NL7408784A (en) 1974-12-31
JPS5024216A (en) 1975-03-15
FR2235112A1 (en) 1975-01-24
DE2430998A1 (en) 1975-01-09
IT1015418B (en) 1977-05-10

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